临床检验杂志 Pub Date : 2020-09-30 DOI: 10.15324/KJCLS.2020.52.3.202

H. You, Y. Ok, Song Hee Lee, S. Lee, Young Ju Lee, Min Ho Lee, S. Hyun

引用次数: 0

Study on the Professionalism of Medical Technologists’ Work in Health Examination Centers: Focusing on the General Health Examination 健康检查中心医疗技术人员工作专业性研究——以健康体检为中心

临床检验杂志 Pub Date : 2020-09-30 DOI: 10.15324/KJCLS.2020.52.3.271

H. Sung

{"title":"Study on the Professionalism of Medical Technologists’ Work in Health Examination Centers: Focusing on the General Health Examination","authors":"H. Sung","doi":"10.15324/KJCLS.2020.52.3.271","DOIUrl":"https://doi.org/10.15324/KJCLS.2020.52.3.271","url":null,"abstract":"Received July 26, 2020 Revised August 15, 2020 Accepted August 20, 2020 “Health examinations” means medical examinations conducted by health examination institutions, including a physical examination, consultation, physical measurement, diagnostic laboratory test (also known as clinical laboratory test, clinical pathology test), pathology test, and Imaging test for checking the health condition and the prevention and early detection of diseases. The types of health examinations include general health examinations, comprehensive health examinations, special health examinations, and other health examinations. The proportion of the general health examination work of medical technologists working at health examination centers has been estimated to comprise more than 50% of the total work. The cost aspect of suspicious diseases can be estimated to be more than 25%. The cost of diagnostic laboratory test has been estimated to be approximately 5%, and the proportion of medical diagnosis use is 70%. The results show that it is time to revisit whether medical technologists are receiving appropriate social, economic, and reasonable policy treatment in health examination work. The future of medical technologists will further expand their professionalism in diagnostic laboratory test and quality control in precision medicine and telemedicine in the future. Therefore, medical technologists will need to participate proactively in government policy decisions related to national health examinations and make efforts to improve treatment. Copyright C 2020 The Korean Society for Clinical Laboratory Science. All rights reserved.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"16 1","pages":"271-277"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85671099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Calculation of the Quality Additional Rate of Clinical Laboratory Test and Review of Application Criteria 临床化验质量附加率的计算及申请标准的检讨

临床检验杂志 Pub Date : 2020-09-30 DOI: 10.15324/KJCLS.2020.52.3.261

B. Yang, Sang-Muk Park, H. Bae, Won Shik Kim, Hun Hee Park, Yong Lim, Y. Kim, S. Choi, Do Hee Bae, J. A. Park

引用次数: 0

Molecular Analysis of Pathogenic Molds Isolated from Clinical Specimen 临床分离病原菌的分子分析

临床检验杂志 Pub Date : 2020-09-30 DOI: 10.15324/KJCLS.2020.52.3.229

J. Lee, K. Kwon, S. Koo

{"title":"Molecular Analysis of Pathogenic Molds Isolated from Clinical Specimen","authors":"J. Lee, K. Kwon, S. Koo","doi":"10.15324/KJCLS.2020.52.3.229","DOIUrl":"https://doi.org/10.15324/KJCLS.2020.52.3.229","url":null,"abstract":"Received September 2, 2020 Revised September 6, 2020 Accepted September 6, 2020 Sixty-five molds isolated from clinical specimens were included in this study. All the isolates were molds that could be identified morphologically, strains that are difficult to identify because of morphological similarities, and strains that require species-level identification. PCR and direct sequencing were performed to target the internal transcribed spacer (ITS) region, the D1/D2 region, and the β-tubulin gene. Comparative sequence analysis using the GenBank database was performed using the basic local alignment search tool (BLAST) algorithm. The fungi identified morphologically to the genus level were 67%. Sequencing analysis was performed on 62 genera and species level of the 65 strains. Discrepancies were 14 (21.5%) of the 65 strains between the results of phenotypic and molecular identification. B. dermatitidis, T. marneffei, and G. argillacea were identified for the first time in Korea using the DNA sequencing method. Morphological identification is a very useful method in terms of the reporting time and costs in cases of frequently isolated and rapid growth, such as Aspergillus. When molecular methods are employed, the cost and clinical significance should be considered. On the other hand, the molecular identification of molds can provide fast and accurate results. Copyright C 2020 The Korean Society for Clinical Laboratory Science. All rights reserved.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"8 1","pages":"229-236"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88940130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age-Related Fecal Calprotectin Concentrations in Healthy Adults 健康成人年龄相关性粪便钙保护蛋白浓度

临床检验杂志 Pub Date : 2020-09-30 DOI: 10.15324/KJCLS.2020.52.3.181

S. Park

{"title":"Age-Related Fecal Calprotectin Concentrations in Healthy Adults","authors":"S. Park","doi":"10.15324/KJCLS.2020.52.3.181","DOIUrl":"https://doi.org/10.15324/KJCLS.2020.52.3.181","url":null,"abstract":"Received August 24, 2020 Revised 1 August 30, 2020 Revised 2 August 30, 2020 Accepted August 31, 2020 Fecal calprotectin (FC) is a marker used for the differential diagnosis of inflammatory bowel disease (IBD). FC is also used to determine the effects of treatment and recurrence prediction because of its non-decomposition by bacteria, relative week stability at room temperature, and its uniform distribution within feces. Healthy male and female adults between the age of 30 and 80 living in Jeju were selected for this study. The FC concentration in the healthy control group (N=45) was distributed widely as 0∼545.9 μg/g and showed a significant difference with age in healthy adults. The FC concentration in adults over 70 years old (80.6 years on average) was 160.3 μg/g. The result is approximately 10 times higher than in adults below 50 years (44 years on average), with FC concentrations at 15.88 μg/g. Moreover, adults over 50 years, with an average age of 59.6, had FC concentrations of 35.46 μg/g, which were two times higher than the below 50-year-old group, confirming the significant correlation between age and FC concentration. As the FC test is a non-invasive and cost-effective objective marker in IBD tests, a suitable cut-off value is required for different ages. This study provides the baseline data for differential diagnoses. Copyright C 2020 The Korean Society for Clinical Laboratory Science. All rights reserved.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"12 1","pages":"181-187"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80659118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Effective Identification of Ochrobactrum anthropi Isolated from Clinical Specimens 临床标本中人类赭杆菌的有效鉴定

临床检验杂志 Pub Date : 2020-09-30 DOI: 10.15324/KJCLS.2020.52.3.221

H. Ko, J. Jo, Hae-Gyeong Baek

{"title":"Effective Identification of Ochrobactrum anthropi Isolated from Clinical Specimens","authors":"H. Ko, J. Jo, Hae-Gyeong Baek","doi":"10.15324/KJCLS.2020.52.3.221","DOIUrl":"https://doi.org/10.15324/KJCLS.2020.52.3.221","url":null,"abstract":"Received July 29, 2020 Revised 1 August 10, 2020 Revised 2 September 3, 2020 Accepted September 3, 2020 Ochrobactrum anthropi is a non-fermentative oxidative gram-negative bacillus that produces oxidase. Distinguishing a mixed culture with non-fermenting bacteria having a similar appearance and oxidase-positive is difficult, and there is a limit to accurate identification with a biochemical identification system. This paper proposes that the Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry Platform (MALDI-TOF) method is useful for classifying bacteria that are difficult to identify using biochemical testing methods. As a result of analyzing five cases of O. anthropi examined using MicroScan, it took 6.5 days to the final report, which was 3.5 days more than the 3.0 days of E. coli. The pus sample in patient 5 was a mixed infection with Achromobacter xylosoxidans, and it took 11.3 days because of multiple subculture and retests. Four patients were over 60 years old with an underlying disease, and the possibility of opportunistic and nosocomial infections could not be excluded. Among them, samples collected after 92 days of hospitalization were resistant to imipenem and meropenem. Therefore, an examination using the MALDI-TOF method will be useful for the rapid and adequate treatment of patients with difficult identification, such as O. anthropi. Copyright C 2020 The Korean Society for Clinical Laboratory Science. All rights reserved.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"36 1","pages":"221-228"},"PeriodicalIF":0.0,"publicationDate":"2020-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81693446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Molecular Subtyping of Methicillin-Resistant Staphylococcus aureus Isolated from Patients’ Nasal Cavity 患者鼻腔耐甲氧西林金黄色葡萄球菌分子分型研究

临床检验杂志 Pub Date : 2020-06-30 DOI: 10.15324/kjcls.2020.52.2.128

Sang-Ha Kim, Sung-Bae Park, Heechul Park, Jun Seong Kim, Jungho Kim, Jiyoung Lee, Jaewon Lim, Young Kwon Kim, Sunghyun Kim

{"title":"Molecular Subtyping of Methicillin-Resistant Staphylococcus aureus Isolated from Patients’ Nasal Cavity","authors":"Sang-Ha Kim, Sung-Bae Park, Heechul Park, Jun Seong Kim, Jungho Kim, Jiyoung Lee, Jaewon Lim, Young Kwon Kim, Sunghyun Kim","doi":"10.15324/kjcls.2020.52.2.128","DOIUrl":"https://doi.org/10.15324/kjcls.2020.52.2.128","url":null,"abstract":"본 연구에서는 환자의 비강으로부터 분리 배양된 총 39건의 MRSA 분리 배양 균주를 이용해 mecA 유전자 검출, SCCmec typing과 mec complex typing을 분석해 보고자 하였다. 임상 환자의 비강으로부터 분리 배양된 MRSA 총 39주 중 SCCmec type-II가 24건, type-II/IVa가 2건, type-II/V가 1건, type-IVa가 1건, not-typeable이 11건으로 분석되었으며, mec complex type A가 29건, not-typeable이 10건이었으며, type B는 없는 것으로 분석 되었다. 결론적으로, 환자의 비강으로부터 분리된 MRSA 분리 배양 균주 중 SCCmec type-II와 mec complex type A 아형이 가장 많이 분포하고 있었으며, 이 결과는 의료기관 획득 MRSA에 관한 다른 연구결과와 유사한 결과를 나타냈다. 이후 환자의 비강으로부터 분리배양된 not-typeable 아형의 MRSA 균주를 대상으로 국내에서 발견되는 새로운 MRSA 아형 규명에 관한 추가 연구가 필요할 뿐만 아니라, MRSA 분리 배양 균주의 아형을 분석함으로써 그 분자적 특성을 분석한 결과를 바탕으로 병원 감염관리를 위한 기초자료를 제공할 수 것으로 사료된다.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"16 1","pages":"128-135"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84556758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protective Effect ofCelastrus orbiculatusThunb Extract on Cultured Neuroglial Cells Damaged by Manganese Dioxide, a Parkinsonism Inducer 红萝卜提取物对诱导帕金森病的二氧化锰损伤的神经胶质细胞的保护作用

临床检验杂志 Pub Date : 2020-06-30 DOI: 10.15324/kjcls.2020.52.2.150

Y. Seo

引用次数: 0

Calculation of Human Resources for Medical Technologist in Diagnostic Testing 诊断检测中医疗技术人员人力资源的计算

临床检验杂志 Pub Date : 2020-06-30 DOI: 10.15324/kjcls.2020.52.2.158

B. Yang, Yong Lim, Y. Kim, Yeon Suk Oh, Do Hee Bae, S. Choi

{"title":"Calculation of Human Resources for Medical Technologist in Diagnostic Testing","authors":"B. Yang, Yong Lim, Y. Kim, Yeon Suk Oh, Do Hee Bae, S. Choi","doi":"10.15324/kjcls.2020.52.2.158","DOIUrl":"https://doi.org/10.15324/kjcls.2020.52.2.158","url":null,"abstract":"본 연구는 상대가치점수제도의 운영 및 개정연구의 합리적인 개선방안과 의료기사 업무 행위의 근거를 도출하였다. 연구에 참여한 7개 기관의 규모를 분석한 결과, 상근 진단검사의학과 전문의 평균 5명, 임상병리사는 평균 53명으로 전문의 1명당 10.6명으로 나타났다. 전문인력영역점수 평균은 18점, 기관별 합계점수의 평균은 78점이었다. 등급 및 가산율(%)은 2∼3등급과 질가산율은 2∼3%으로 큰 편차는 나타나지 않았다. 병리검사 및 생리기능검사를 제외한 건강보험청구 평균 진단검사건수는 9,618,062건에 상대가치점수 총합의 5%는 4,378,146점이었다. 자료포락분석(DEA)분석결과 임상병리사의 적정인력은 상대가치 점수 49,974점당 1명으로 나타났다. 결론적으로 본 연구의 분석결과 임상병리사의 적정인력은 상대가치 점수 총합 5만점당 1명으로 설정하는 것이 바람직할 것으로 판단되며, 인력의 생산성 제고 및 보건 의료 자원의 균형 배분을 위한 근거로 활용될 수 있을 것으로 사료된다.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"51 1","pages":"158-163"},"PeriodicalIF":0.0,"publicationDate":"2020-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77591022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

自组装核酸适配子探针在深部真菌感染可视化检测中的应用自组装核酸适配子探针在深部真菌感染可视化检测中的应用

临床检验杂志 Pub Date : 2020-01-28 DOI: 10.13602/j.cnki.jcls.2020.01.01

孟伟 | 王雯 | 章宏祥 | 周发友 | 唐晓磊

引用次数: 0

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