临床检验杂志 Pub Date : 2017-01-01 DOI: 10.15324/KJCLS.2017.49.1.48

Jung-Kyu So, Kim Jung Suk, Young-Hee Lee, Dae-Jung Kim, Chang-Eun Park

引用次数: 0

게르마늄 농도를 증가 시킨 동충하초 균사체 열수 추출액의 항암효과 增加锗浓度的冬虫夏草菌丝体热水提取液具有抗癌效果

临床检验杂志 Pub Date : 2017-01-01 DOI: 10.15324/KJCLS.2017.49.2.69

Jeong Su Choi, Ji Hye Heo, Dae-jin Kim, Sumin Namkung, Lee Taebok, Min Woo Lee, Suhng Wook Kim

引用次数: 0

갑상선기능이상 환자에서 크레아티닌과 시스타틴을 이용한 사구체여과율 검사결과의 상관성 연구 甲状腺功能异常患者肾小球滤过率利用肌氨酸与视他汀的相关性研究

临床检验杂志 Pub Date : 2017-01-01 DOI: 10.15324/KJCLS.2017.49.3.203

Gun-Woong Lim, Park , Hyung Doo, H. Sung

引用次数: 0

The Sensitivity Comparison of Immunodiagnostic Assays for Diagnosing Dengue Fever 几种免疫诊断方法诊断登革热的敏感性比较

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.275

M. Zahoor, Haji Bahadar, Salah Uddin, S. Naz

引用次数: 1

A Review of the Characteristics of Early Apparatus and Methods for Hemoglobin Estimation 早期血红蛋白测定仪器及方法的特点综述

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.401

Young-Il Kwon

引用次数: 1

Building the Data Mart on Antibiotic Usage for Infection Control 感染控制中抗生素使用数据集市的建立

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.348

I. Rheem

{"title":"Building the Data Mart on Antibiotic Usage for Infection Control","authors":"I. Rheem","doi":"10.15324/KJCLS.2016.48.4.348","DOIUrl":"https://doi.org/10.15324/KJCLS.2016.48.4.348","url":null,"abstract":"Data stored in hospital information systems has a great potential to improve adequacy assessment and quality management. Moreover, an establishment of a data warehouse has been known to improve quality management and to offer help to clinicians. This study constructed a data mart that can be used to analyze antibiotic usage as a part of systematic and effective data analysis of infection control information. Metadata was designed by using the XML DTD method after selecting components and evaluation measures for infection control. OLAP — a multidimensional analysis tool — for antibiotic usage analysis was developed by building a data mart through modeling. Experimental data were obtained from data on antibiotic usage at a university hospital in Cheonan area for one month in July of 1997. The major components of infection control metadata were antibiotic resistance information, antibiotic usage information, infection information, laboratory test information, patient information, and infection related costs. Among them, a data mart was constructed by designing a database to apply antibiotic usage information to a star schema. In addition, OLAP was demonstrated by calculating the statistics of antibiotic usage for one month. This study reports the development of a data mart on antibiotic usage for infection control through the implementation of XML and OLAP techniques. Building a conceptual, structured data mart would allow for a rapid delivery and diverse analysis of infection control information.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"22 1","pages":"348-354"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81194621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Analysis of the Effects of Bone Marrow Biopsy Decalcification Methods on Histopathological Examination 骨髓活检脱钙方法对组织病理学检查的影响分析

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.371

J. Park, K. Han

{"title":"Analysis of the Effects of Bone Marrow Biopsy Decalcification Methods on Histopathological Examination","authors":"J. Park, K. Han","doi":"10.15324/KJCLS.2016.48.4.371","DOIUrl":"https://doi.org/10.15324/KJCLS.2016.48.4.371","url":null,"abstract":"Decalcification is routinely performed to obtain a pathological diagnosis using bone marrow biopsy. During the decalcification process using a conventional acidic solution, such as HCl, the antigenicity of tissue is damaged. Especially DNA and RNA in the bone marrow are impaired. Hence, there is the need for a standardized decalcification protocol that preserves the antigenicity of tissue. To this end, we compared the effects of two commonly used decalcifiers: Commercial decalcifier (Calcl-Clear Rapid, HCl) and the EDTA (12.5%, pH 7.0). Bone marrow biopsies sampled from 71 patients were decalcified in accordance with the protocols of respective groups—HCI versus EDTA. The differences of decalcification protocols were analyzed with respect to Hematoxylin & Eosin staining, Gomori’sreticulum staining, and immunohistochemical staining and molecular analysis. Immunohistochemical staining used Ki-67, CD20 and CD138 as primary antibodies and molecular analysis was conducted through the DNA concentration analysis, in situ hybridization (ISH) and immunoglobulin heavy chain (IGH) gene rearrangement. On the routine histopathology analysis, there was no difference between HCl and EDTA. Moreover, in case of immunohistochemical staining, the cytoplasmic membrane or cytoplasmic CD markers was well preserved. However, nuclear proteins, such as Ki-67, were stained with low quality. Conversely, according to the molecular analysis, the EDTA protocol preserved the DNA and RNA compared with the HCI. The differences of DNA quantity and quality were statistically significant between protocols of HCl and EDTA. We used 38 cases in HCl and 12 cases in EDTA. Consequently, the EDTA protocol maintains the antigenicity of the protein on tissue and is acceptable for examination with molecular base analysis. Decalcification of bone marrow biopsy by EDTA is highly recommended for the examination of immunohistochemical staining and molecular analysis.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"9 1","pages":"371-377"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90717175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study on Changes in Antimicrobial Resistant Staphylococcus aureus from Wound Isolates in a South Korean University Hospital for the Past 10 Years (2006, 2016) 韩国某大学医院近10年伤口分离株耐药金黄色葡萄球菌变化研究(2006,2016)

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.335

Seong-No Hong, Joon Kim, H. Sung

{"title":"A Study on Changes in Antimicrobial Resistant Staphylococcus aureus from Wound Isolates in a South Korean University Hospital for the Past 10 Years (2006, 2016)","authors":"Seong-No Hong, Joon Kim, H. Sung","doi":"10.15324/KJCLS.2016.48.4.335","DOIUrl":"https://doi.org/10.15324/KJCLS.2016.48.4.335","url":null,"abstract":"Staphylococcus aureus, which is generally susceptible to the involvement route in community, is mostly MSSA. However, CA-MRSA is recently increased. Abuse of antibiotics and glycopeptides may increase VISA and VRSA. This study was conducted to investigate the changes on the antibiotic resistance prevalence and antibiotic susceptibility patterns of Staphylococcus aureus isolated from the wound of patients in a university hospital for the past 10 years. This study showed that antibiotic resistance was higher in males than in females; moreover, the antibiotic resistance rates increased with age. The resistance rate for penicillin, oxacillin, erythromycin, gentamicin, clindamycin, tetracycline, ciprofloxacin, fusidic acid, trimethoprim/sulfamethoxazole, clindamycin, and rifampicin was, respectively, 97.7%, 60.5%, 57.4%, 48.8%, 41.1%, 44.2%, 44.2%, 14.7%, 13.2% and 3.9% in 2006. The resistance rate for penicillin, oxacillin, erythromycin, gentamicin, clindamycin, tetracycline, ciprofloxacin, fusidic acid, trimethoprim/sulfamethoxazole, fusidic acid, clindamycin, and rifampicin was, respectively 95.9%, 62.6%, 55.7%, 28.6%, 50.3%, 34.7%, 38.8%, 34.0%, 2.7% and 8.2% in 2016. Vancomycin, linezolid, quinupristin/dalfopristin, and teicoplanin exhibited 100% in antibiotic susceptibility. In particular, fusidic acid resistance was increased by 19.3% in 2016. Compared with 2006, the decreased point, 12.4% was susceptible and was statistically significant. Therefore, this study suggests that periodic review and understanding of microbial and antibiotic changes should continue to investigate appropriate antibiotic susceptibility.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"219 2 1","pages":"335-342"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90758989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

A Distribution of Keratinophilic Fungi Isolated from the Soil of Haeundae Beach in Korea 韩国海云台海滩土壤中分离的嗜角真菌的分布

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.343

So-Joong Kim, S. Kim

引用次数: 2

Interrelationships and Differences of Brachial-Ankle Pulse Wave Velocity (baPWV), Body Composition and Cardiovascular Variables between Genders Who Have Been Exercised or Not in Elderly 老年人运动与不运动的性别间臂踝脉搏波速度、体成分及心血管变量的相互关系及差异

临床检验杂志 Pub Date : 2016-12-31 DOI: 10.15324/KJCLS.2016.48.4.378

Jong-Woo Lee, Dae-Sik Kim, E. Cho

{"title":"Interrelationships and Differences of Brachial-Ankle Pulse Wave Velocity (baPWV), Body Composition and Cardiovascular Variables between Genders Who Have Been Exercised or Not in Elderly","authors":"Jong-Woo Lee, Dae-Sik Kim, E. Cho","doi":"10.15324/KJCLS.2016.48.4.378","DOIUrl":"https://doi.org/10.15324/KJCLS.2016.48.4.378","url":null,"abstract":"This study sought to investigate interrelationships and differences of brachial-ankle pulse wave velocity (baPWV), body composition and cardiovascular variables between genders who have been exercised or not in elderly. One hundred fifty participants were classified four groups. Especially out of variables, in male elderly group who had participated in exercise program the PWV range were significantly correlated with muscle mass (r=0.357, p=0.026), SBP (r=0.468, p=0.003), right baPWV (r=0.406, p=0.010), and left baPWV (r=0.333, p=0.038). In male elderly group who had not participated in exercise program, the PWV range were significantly correlated with heart rate (r=0.395, p=0.014), right baPWV (r=0.598, p=0.000), and left baPWV (r=0.602, p=0.000). In female elderly group who had participated in exercise program, the PWV range were significantly correlated with name of diagnosis (r=0.321, p=0.044), SBP (r=0.399, p=0.011), DBP (r=0.545, p=0.000), right baPWV (r=0.648, p=0.000), and left baPWV (r=0.676, p=0.000). In female elderly group who had not participated in exercise program, the PWV range were significantly correlated with age (r=0.471, p=0.003), right baPWV (r=0.836, p=0.000), and left baPWV (r=0.801, p=0.000). The PWV among four groups were not significant different after experiment. However, there were significant differences in the waist/hip ratio (F=9.197, p=0.000), muscle mass (F=74.295, p=0.000), and %fat (F=35.045, p=0.000) from body composition. And there were significant differences in the SBP (F=3.525, p=0.017) after experiment. In conclusion, these data show that regular exercise is associated with arterial compliance (PWV range, right or left PWV) and differed from genders. In other words, this paper may support the concept that regular exercise program may exert a protective effect on arterial compliance, body composition and cardiovascular systems.","PeriodicalId":10080,"journal":{"name":"临床检验杂志","volume":"1 1","pages":"378-387"},"PeriodicalIF":0.0,"publicationDate":"2016-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89537500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

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