{"title":"Synthesis of a novel core-shell magnetic covalent organic framework for the enrichment and detection of AFM1 and AFM2 in milk and dairy products using HPLC-MS/MS","authors":"Dongyue Zhao , Xiuli Xu , Wei Wu , Xiujuan Wang , Feng Zhang","doi":"10.1016/j.jfutfo.2025.04.009","DOIUrl":"10.1016/j.jfutfo.2025.04.009","url":null,"abstract":"<div><div>Magnetic covalent organic framework nanocomposite denoted as Fe<sub>3</sub>O<sub>4</sub>@TPBD-BTA with core-shell structure was fabricated via a simple template-mediated precipitation polymerization method at mild conditions. The polyimine network shell was created through the polymerization of N,N,N′,N′-tetrakis(p-aminophenyl)-p-phenylenediamine (TPBD) and biphenyl-3,3′,5,5′-tetracarbaldehyde (BTA) in tetrahydrofuran (THF) by the Schiff-base reaction. Featuring with large good solution dispersibility, and high stability, the obtained Fe<sub>3</sub>O<sub>4</sub>@TPBD-BTA exhibited high adsorption capacities and fast adsorption for zearalenone and its Aflatoxin (AFT). The adsorption isotherms showed multilayer adsorption dominated at low concentration and monolayer adsorption at high concentration between the interface of AFs and Fe<sub>3</sub>O<sub>4</sub>@TPBD-BTA. With the Fe<sub>3</sub>O<sub>4</sub>@TPBD-BTA as sorbent, a magnetic solid-phase extraction-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method was established for simultaneous adsorption and detection of five ZEAs in complex samples. The proposed method displayed favorable linearity, low limits of detection (0.006 5 − 0.008 2 μg/kg). The developed method has been applied for real sample analysis, with recoveries of 81.0%−109.6%. These results showed that Fe<sub>3</sub>O<sub>4</sub>@TPBD-BTA has a good application potential for the adsorption of AFs in milk and dairy products.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 3","pages":"Pages 413-420"},"PeriodicalIF":7.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Future FoodsPub Date : 2026-05-01Epub Date: 2025-05-06DOI: 10.1016/j.jfutfo.2024.08.015
Nashi K. Alqahtani
{"title":"Bioactive compounds and nutritional composition of butternut pumpkins (Cucurbita moschata) cultivated in Saudi Arabia","authors":"Nashi K. Alqahtani","doi":"10.1016/j.jfutfo.2024.08.015","DOIUrl":"10.1016/j.jfutfo.2024.08.015","url":null,"abstract":"<div><div>This study analyzed the bioactive compound content and nutritional composition of Hassawi Popper (<em>Cucurbita moschata</em>), a local landrace of pumpkin cultivated in Saudi Arabia, and compared it with other pumpkin cultivars from different regions imported to Saudi Arabia. The chemical composition, pH, color parameters, amino acid profile, mineral composition, carotenoid profile, vitamin content, phenolic acid and flavonoid content, and antioxidant activity of Hassawi Popper and two other pumpkin varieties (<em>Cucurbita maxima</em> and <em>Cucurbita pepo</em>) were determined using various analytical methods. The results showed that Hassawi Popper had higher levels of protein, ash, total dietary fiber, calcium, magnesium, phosphorus, manganese, iron, zinc, copper, lysine, isoleucine, phenylalanine, aspartic acid, serine, glutamic acid, glycine, alanine, proline, cysteine, beta-carotene, alpha-carotene, vitamin C, vitamin B1, vitamin B2, vitamin B3, vitamin B5, vitamin B6, vitamin B9, total phenolic content (TPC), total flavonoid content (TFC), condensed tannin content (CTC), and antioxidant activity than the other two varieties. These findings suggest that Hassawi Popper is a valuable source of bioactive compounds and nutrients that can provide health benefits for consumers. The study also provides useful information for further research on the genetic diversity and phytochemical properties of Cucurbita moschata cultivars from different regions.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 3","pages":"Pages 446-459"},"PeriodicalIF":7.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Future FoodsPub Date : 2026-05-01Epub Date: 2025-05-19DOI: 10.1016/j.jfutfo.2025.04.011
Yuying Han , Hongyi Liu , Jun Chen , Ruihong Liang , Taotao Dai , Chengmei Liu , Chengliang Lv , Ping Huang , Xiaohong Liang , Lizhen Deng
{"title":"Whole chicken powder produced by industry-scale microfluidizer system: Improvement on physicochemical properties, protein digestibility and volatile flavor","authors":"Yuying Han , Hongyi Liu , Jun Chen , Ruihong Liang , Taotao Dai , Chengmei Liu , Chengliang Lv , Ping Huang , Xiaohong Liang , Lizhen Deng","doi":"10.1016/j.jfutfo.2025.04.011","DOIUrl":"10.1016/j.jfutfo.2025.04.011","url":null,"abstract":"<div><div>This work examined the performance of an innovative industry-scale microfluidizer system (ISMS) at various pressures (0, 30, 60, 90 and 120 MPa) on processing chicken powder (CP). Results indicated that ISMS considerably destroyed the tissue structure of sample. With the treatment intensity of ISMS increased from 0 to 120 MPa, the particle size (D90) of CP significantly decreased from 153.00 to 50.21 μm, which was much lower than those of commercial samples (124.00 and 99.70 μm). Increasing the ISMS pressure also greatly improved the quality of CP, such as the bulk density, tapped density, and <em>L*</em> values increased. ISMS treatment well preserved the nutrients, the contents and <em>in vitro</em> digestibility of protein were significantly higher than those of commercial samples. Moreover, the content of main flavor components increased after ISMS treatment. Therefore, the ISMS would be a potential technique to process CP with high quality and efficiency.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 3","pages":"Pages 470-478"},"PeriodicalIF":7.2,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jingyi Huang, Jieling Chen, Xinyu Li, Ying Wei, Y Liu, Qing Zhu, Lei Wang
{"title":"Cafestol alleviated hyperuricemia by inhibiting uric acid synthesis through the regulation of PPARγ/PPARα/XOD pathway","authors":"Jingyi Huang, Jieling Chen, Xinyu Li, Ying Wei, Y Liu, Qing Zhu, Lei Wang","doi":"10.1016/j.jfutfo.2026.04.004","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2026.04.004","url":null,"abstract":"• Network pharmacology combining molecular docking analysis suggests that cafestol may alleviate hyperuricemia (HUA) through interaction with PPARγ. • In human hepatocyte HepG2 cells, cafestol activated PPARγ, enhanced the formation of the PPARγ–RXRα heterodimer and suppressed PPARα-mediated XOD expression, leading to reduced endogenous uric acid (UA) synthesis. • In HUA mice, cafestol alleviated HUA by activating PPARγ to decrease endogenous UA production. It also inhibited liver injury, improved cholesterol metabolism and kidney function, as well as promoted urinary UA excretion. Cafestol, a natural diterpenoid found in coffee, exhibits various bioactive properties, such as regulation of lipid metabolism, antioxidant activity, and anti-inflammation. Nevertheless, its potential role in managing hyperuricemia (HUA) has not been well studied. This study aimed to investigate the beneficial effects of cafestol on HUA and to clarify its underlying molecular mechanism. Potential targets of cafestol were predicted using network pharmacology and molecular docking. Its effects on uric acid (UA) production were further verified in vitro and in vivo . Integrated analyses identified peroxisome proliferator-activated receptor gamma (PPARγ) as a key target of cafestol. In human hepatocytes HepG2, cafestol upregulated PPARγ expression, promoted its heterodimer formation with retinoid X receptor alpha (RXRα), and suppressed UA synthesis along with the expression of PPARα and xanthine oxidase (XOD). Knockdown of PPARγ abolished the reduction in UA and the downregulation of PPARα and XOD by cafestol, whereas PPARα knockdown had no effect on PPARγ expression but still decreased UA production. In a mouse model of HUA, cafestol significantly reduced serum levels of UA, AST, ALT, total cholesterol, and LDL-cholesterol, while increasing HDL-cholesterol. It also elevated 24-h urine volume and urinary UA excretion and improved kidney function. Moreover, cafestol activated hepatic PPARγ, enhanced PPARγ–RXRα heterodimerization, and suppressed PPARα/XOD expression in HUA mice. This study demonstrates that cafestol alleviates HUA by activating PPARγ, which subsequently decreases UA production through inhibiting PPARα-mediated XOD expression. These results highlight the potential of cafestol as a promising functional food component for the prevention or management of HUA.","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147878439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metagenomic and Volatilomic Analysis of Fermented Sausages Inoculated with Lactobacillus plantarum CD101 and Staphylococcus simulans NJ201","authors":"Meiqin Feng, Pengfei Shi, Jingyang Liu, Jian Sun","doi":"10.1016/j.jfutfo.2026.04.002","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2026.04.002","url":null,"abstract":"• Lactobacillus plantarum CD101 and simulated Staphylococcus simulans NJ201 improve the color and flavor of fermented sausage. • Inoculation with mixed starter cultures inhibited the growth of spoilage and pathogenic bacteria, resulting in reduced biogenic amine content. • The mixed starter culture affected eight metabolic pathways, promoted the conversion of protein and fat to volatile flavor compounds, and discovered the key genes and enzymes of metabolic pathway of volatile flavor substances. This study explored the effects of Staphylococcus simulans NJ201 and Lactobacillus plantarum CD101 , used individually or in combination, on the quality and flavor characteristics of fermented sausages. The results showed that the pH value of sausages inoculated with the mixed starter culture was significantly lower than that of the control group with p <0.05. Color analysis indicated that bacterial inoculation increased the a*/b* value and L* value of the sausages with p <0.05. The mixed starter culture also significantly changed the composition of volatile compounds in the sausages, increasing the contents of alcohols and esters while decreasing the contents of acids and aldehydes. Metagenomic analysis showed inoculated strains suppressed spoilage/pathogenic bacteria and reduced biogenic amines; KEGG analysis indicated mixed strains modulated 8 metabolic pathways to promote flavor compound formation. The above research results indicate that the combination of Lactobacillus plantarum CD101 and Staphylococcus simulans NJ201 as a mixed starter culture significantly enhances the flavor and color of sausages. At the same time, the results of metagenomics and bioamines also ensured its safety.","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147877878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Future FoodsPub Date : 2026-03-01Epub Date: 2025-06-30DOI: 10.1016/j.jfutfo.2024.04.009
Shubhangi Sharma , Khalid Mehmood Wani , Shaik Mahammad Mujahid, Laksmi S. Jayan, Sneha Soundara Rajan
{"title":"Review on Pectin: Sources, Properties, Health Benefits and Its Applications in Food Industry","authors":"Shubhangi Sharma , Khalid Mehmood Wani , Shaik Mahammad Mujahid, Laksmi S. Jayan, Sneha Soundara Rajan","doi":"10.1016/j.jfutfo.2024.04.009","DOIUrl":"10.1016/j.jfutfo.2024.04.009","url":null,"abstract":"<div><div>Agricultural lignocellulose wastes are an excellent substrate for the production of value-added products (such as pectin). Natural macromolecules have gained popularity due to their biocompatibility, low toxicity, and biodegradability. Pectin is the most intricate polysaccharide found in the cell walls of plants, both in terms of structure and function. Pectin plays a crucial role in various aspects of plant biological processes, including growth, morphology, development, and defense. Additionally, it functions as a gelling and stabilizing agent in a wide range of food and speciality products. Moreover, pectin contributes to the texture and rheological properties of various food systems. Additionally, it exerts positive effects on human health and possesses a multitude of biomedical applications. Furthermore, as a biopolymer, pectin has garnered attention for its potential applications in active packaging systems. Pectin can be utilized alongside with an extensive variety of biopolymers with distinct characteristics and functionalities. In this context, this review presents an in-depth investigation of pectin, including its structure, sources, properties, and wide-ranging applications in the fields of biomedicine and food industry.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 2","pages":"Pages 205-219"},"PeriodicalIF":7.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Future FoodsPub Date : 2026-03-01Epub Date: 2025-07-03DOI: 10.1016/j.jfutfo.2024.05.015
Roma Ehsan , Luciane Barbosa Pessoa , Waqas Younis , Wajiha Manzoor , Muhammad Nasir Hayat Malik , Muhammad Naveed Mushtaq , Tariq G. Alsahli , Muryam Abdul Razzaq , Francislaine Aparecida dos Reis Lívero , Arquimedes Gasparotto Junior
{"title":"The potential of volatile oil farnesol as a new treatment for hypertension and improvement of vascular function in hypertensive rats","authors":"Roma Ehsan , Luciane Barbosa Pessoa , Waqas Younis , Wajiha Manzoor , Muhammad Nasir Hayat Malik , Muhammad Naveed Mushtaq , Tariq G. Alsahli , Muryam Abdul Razzaq , Francislaine Aparecida dos Reis Lívero , Arquimedes Gasparotto Junior","doi":"10.1016/j.jfutfo.2024.05.015","DOIUrl":"10.1016/j.jfutfo.2024.05.015","url":null,"abstract":"<div><div>Farnesol, an acyclic sesquiterpene alcohol derived from medicinal plants, presents possible antioxidant and vasodilator effects. This study thoroughly examines the preventive impact of farnesol on <em>N</em><sup>G</sup>-nitro-<em>L</em>-arginine methyl ester (<em>L</em>-NAME)-induced hypertension and vascular dysfunction in rats, investigating its potential cardioprotective effect. Initially, the acute hypotensive effects of farnesol were evaluated in normotensive rats through intravenous administration, with amlodipine, <em>L</em>-NAME, atropine, and indomethacin used to uncover potential mechanisms. Subsequent research focused on the therapeutic effects of orally administered farnesol on hypertension and vascular dysfunction induced by <em>L</em>-NAME over a 4-week period. Various parameters, including blood pressure, body weight, urine characteristics, oxidative stress markers, lipid profile, serum nitric oxide levels, and gene expression, were analyzed. Farnesol demonstrated hypotensive and diuretic effects in normotensive rats, potentially through calcium channels and the cyclooxygenase pathway. In hypertensive rats, farnesol, similar to captopril, effectively lowered blood pressure and restored various biomarkers, indicating its promising potential as an antihypertensive agent.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 2","pages":"Pages 279-291"},"PeriodicalIF":7.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Future FoodsPub Date : 2026-03-01Epub Date: 2025-06-30DOI: 10.1016/j.jfutfo.2024.04.010
Qinyu Li , Siqi Li , Aruhan Chen , Congying Huang , Jiayin Chang , Na Zhang , Minhui Li
{"title":"Dracocephalum moldavica L. tea alleviates high-fat diet-induced hyperlipidemia in rats via gut microbiota and lipid metabolism","authors":"Qinyu Li , Siqi Li , Aruhan Chen , Congying Huang , Jiayin Chang , Na Zhang , Minhui Li","doi":"10.1016/j.jfutfo.2024.04.010","DOIUrl":"10.1016/j.jfutfo.2024.04.010","url":null,"abstract":"<div><div>Hyperlipidemia is a common metabolic disorder and a major risk factor for cardiovascular diseases. <em>Dracocephalum moldavica</em> L., a species of <em>Dracocephalum</em> in the family Labiatae, has a long history of medicinal use, often as tea (non-<em>Camellia</em> tea) to lower blood sugar and lipid levels. However, its exact mechanism of action remains unknown, hindering its therapeutic effectiveness. In this study, the lipid-regulating mechanism of the ethyl acetate extract of <em>D. moldavica</em> (EAD) was evaluated. The chemical constituents of EAD were preliminarily characterized using ultra-high performance liquid chromatography. A rat model of hyperlipidemia was induced by a high-fat diet and different doses of EAD were administered. Body weight, liver weight, and kidney weight were measured, along with biochemical indexes related to lipid metabolism. Intestinal content samples were analyzed using 16S rRNA sequencing technology to determine differences in intestinal bacterial composition. Differential metabolites were identified by serum metabolomics. The results showed that EAD reduced the weight of rats on a high-fat diet, along with liver weight and kidney weights, approaching levels similar to those in the normal group. Biochemical indexes related to lipid metabolism in the serum of rats on a high-fat diet were also improved. Furthermore, daily supplementation of EAD induced structural changes in the gut microbiota of rats, particularly by regulating the relative abundance of important microbes. Additionally, enrichment of metabolite metabolic pathways in plasma revealed the regulation of amino acid metabolism and primary bile acid synthesis after EAD administration. These results indicate that EAD alleviates hyperlipidemia in rats by regulating lipid metabolism and gut microbiota, providing insight into dyslipidemia regulation by <em>D. moldavica</em>.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 2","pages":"Pages 220-231"},"PeriodicalIF":7.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Journal of Future FoodsPub Date : 2026-03-01Epub Date: 2025-07-02DOI: 10.1016/j.jfutfo.2024.11.011
Pan Xu , Fan Jia , Yao Xu , Tao Zheng , Hui Zheng , Xinwen Dai , Yong Yang
{"title":"Effect of vacuum microwave drying and steaming treatment on quality of Poria cocos","authors":"Pan Xu , Fan Jia , Yao Xu , Tao Zheng , Hui Zheng , Xinwen Dai , Yong Yang","doi":"10.1016/j.jfutfo.2024.11.011","DOIUrl":"10.1016/j.jfutfo.2024.11.011","url":null,"abstract":"<div><div>Drying is a crucial factor affecting the processing quality of <em>Poria cocos</em>, a renowned medicinal and edible material in China. However, the current process named “hot-air drying (HAD) after steaming” exhibits drawbacks of extended processing time, elevated expenses, and uncontrollable quality. In order to evaluate the effect of vacuum microwave drying (VMD) and steaming on the quality of <em>P. cocos</em>, the physical and chemical quality was investigated among four samples subjected to different drying schemes: direct drying by VMD (PC-VMD), drying by VMD after steaming (SPC-VMD), direct drying by HAD (PC-HAD) and drying by HAD after steaming (SPC-HAD). Results indicate that compared to the HAD samples, the drying time required for the VMD samples is reduced by 2/3, and the alcohol extracts contents increases by 11.54% and 13.73%, while the water/oil-holding capacity have also improved to varying degrees. While steaming results in losses of alcohol extracts of 8.97% and 11.23%, and a loss of water-soluble polysaccharide content of 10.81% and 16.32% comparing with non-steamed schemes. The LC-MS analysis revealed that the triterpenoid composition compounds is similar across the four samples, but the relative amount of pachymic acid in the VMD samples are 9.09% and 18.80% higher than HAD samples, and the VMD also demonstrates varying advantages in retaining 8 other key triterpenoids. Additionally, the relative content of these substances in the non-steamed samples is higher than steaming samples. The GC-MS analysis showed that steaming obviously resulted in the loss of some volatile components. E-tongue and E-nose analysis show the taste patterns in the four samples was similar. Therefore, VMD can improve the drying efficiency and quality of <em>P. cocos</em>, whereas steaming can diminish the quality. In conclusion, steaming is a non-essential process, and direct drying by VMD (PC-VMD) is a high quality and high efficiency drying schemes of <em>P. cocos</em>.</div></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"6 2","pages":"Pages 319-329"},"PeriodicalIF":7.2,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144771551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}