Journal of Future Foods最新文献

{"title":"Tetramethylpyrazine and paeoniflorin combination (TMP-PF) inhibits angiogenesis in atherosclerosis via miR-126/VEGF/VEGFR2 signaling pathway","authors":"Yahui Yuan ,&nbsp;Rong Yuan ,&nbsp;Qiqi Xin ,&nbsp;Yu Miao ,&nbsp;Ying Chen ,&nbsp;Rui Gao ,&nbsp;Weihong Cong","doi":"10.1016/j.jfutfo.2023.07.010","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.07.010","url":null,"abstract":"<div><p>Angiogenesis in atherosclerosis (AS) promotes plaque destabilization. miR-126 has a significant role in angiogenesis. Tetramethylpyrazine (TMP) and paeoniflorin (PF) have anti-atherosclerotic effects. However, the miR-126-related mechanisms of TMP and PF combination (TMP-PF) on angiogenesis in AS have not been understood. To explore the mechanism of TMP-PF on angiogenesis in AS targeting miR-126. Human umbilical vein endothelial cells (HUVECs) were assigned into the control, model, TMP-PF, TMP-PF + miR-126 inhibitor, and simvastatin groups. HUVECs were transfected with miR-126 inhibitor or negative control, incubated with oxidized low-density lipoprotein (ox-LDL) to establish AS model, and then treated with TMP-PF or simvastatin. Cell proliferation, migration, and tube formation assays are conducted, and the expression of angiogenesis-related factors were detected by enzyme-linked immunosorbent assay (ELISA) and Western blotting. The expression level of miR-126 was confirmed by polymerase chain reaction (PCR).</p><p>ox-LDL promoted HUVECs proliferation, migration, and tube formation, downregulated miR-126 expression, and increased the expression of VEGF, VEGFR2, bFGF, and FGFR1. TMP-PF inhibited proliferation, migration, and tube formation, upregulated miR-126 expression and decreased the expression of VEGF, VEGFR2, bFGF, and FGFR1 in ox-LDL-induced HUVECs. However, the effects of TMP-PF on angiogenesis and the expression of miR-126, VEGF, VEGFR2, and FGFR1 were abolished by miR-126 inhibitor. TMP-PF suppressed angiogenesis in AS by regulating miR-126/VEGF/VEGFR2 pathway, which might elucidate the underlying mechanism of TMP-PF in alleviating AS.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"4 3","pages":"Pages 280-287"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49891709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influences of Lactiplantibacillus plantarum and Saccharomyces cerevisiae fermentation on the nutritional components, flavor property and lipid-lowering effect of highland barley","authors":"Juan Bai,&nbsp;Linzhao He,&nbsp;Jinfu Zhang,&nbsp;Xiangyue Gu,&nbsp;Beiqi Wu,&nbsp;Anlin Wang,&nbsp;Ying Zhu,&nbsp;Jiayan Zhang,&nbsp;Yansheng Zhao,&nbsp;Jie Yuan,&nbsp;Xiang Xiao","doi":"10.1016/j.jfutfo.2023.07.008","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.07.008","url":null,"abstract":"<div><p>Highland barley is a well-known cereal in Qinghai-Tibet Plateau area with high nutritional value, which has been reported to be a health-promoting grain for the obesity and the diabetes. Fermentation by certain microbiota can improve the flavor property and nutritional characteristics. In the present study, <em>Lactiplantibacillus plantarum</em> and <em>Saccharomyces cerevisiae</em> were singly or jointly applied to ferment highland barley, and the profile of volatile substances and lipid-lowering effects of the respective extracts were analyzed. Results indicated that either <em>L. plantarum</em> or <em>S. cerevisiae</em> or co-fermentation could consume the polysaccharides of highland barley to provide energy, and dramatically increase the contents of total protein and polyphenol. Gas chromatography-mass spectrometry (GC-MS) analysis revealed that the presence of <em>S. cerevisiae</em> was critical for production of the pleasant flavors, especially for the ethyl ester substances including hexadecanoic acid ethyl, hexanoic acid ethyl ester and so on. Meanwhile, we found that fermented highland barley extracts by <em>L. plantarum</em> exhibited stronger lipid-lowering effects in <em>Caenorhabditis elegans</em> than that by <em>S. cerevisiae</em>, while the co-fermentation not only emitted pleasant odors but also exerted high hypolipidemic function. In all, co-fermentation by <em>L. plantarum</em> and <em>S. cerevisiae</em> was proposed to be a promising processing to improve the flavor and functional properties of highland barley.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"4 3","pages":"Pages 258-266"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49891711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of novel targets and mechanisms of wogonin on lung cancer, bladder cancer, and colon cancer","authors":"Lin Zhou ,&nbsp;Yunran Hu ,&nbsp;Changxing Gao ,&nbsp;Congci Yu ,&nbsp;Zhiting Sun ,&nbsp;Weihong Ge ,&nbsp;Hui Yang","doi":"10.1016/j.jfutfo.2023.07.009","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.07.009","url":null,"abstract":"<div><p>Wogonin (WOG) has been demonstrated to have anti-cancer activity, but the mechanisms remain unclear. In this study, new targets of WOG were predicted for lung cancer, bladder cancer, and colon cancer by using bioinformatics methods. WOG might primarily suppress cancers via regulating arachidonic acid, Ras, MAPK, linoleic acid, PI3K-Akt, and folate biosynthesis pathways. 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxymethoxyphenyl)-2-(4-sulfophenyl)-2<em>H</em>-tetrazolium (MTS) assay showed that WOG inhibited the proliferation of A549 cells. Real-time quantitative reverse transcription PCR (RT-qPCR) results indicated that anti-lung cancer effect of WOG was achieved by regulating the expression of 18 target genes, including <em>AKR1B10, AKR1C3, BDNF, CAV1, CXCL2, CYP2B6, CYP4F3, DAO, EGF, ENO3, IL6, PLA2G1B, PLA2G2F, PLA2G4A, PTGES, SLCO1B1, SLCO1B3</em>, and <em>TFAP2A</em>. The Kaplan-Meier survival curves further confirmed that <em>DAO, PLA2G1B, SLCO1B3</em> and <em>TFAP2A</em> were essential targets via which WOG affected lung cancer survival. Moreover, <em>BDNF, FGF2</em>, and <em>PTGS1</em> were predicted to be the targets via which WOG alleviated cancer proliferation and invasion in bladder cancer. As for colon cancer, WOG might induce autophagy and inhibit proliferation by down-regulating <em>NTF4</em> and <em>TH</em>. The study will provide clue for using WOG as a promising antineoplastic agent in basic and translational research, and bring light to the application of herbs containing WOG as food supplements.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"4 3","pages":"Pages 267-279"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49891712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review: the mechanism of plant-derived polysaccharides on osteoblasts and osteoclasts","authors":"Mengjie Ren ,&nbsp;Adel F. Ahmed ,&nbsp;Meng Li ,&nbsp;Menghan Li ,&nbsp;Zhiruo Yan ,&nbsp;Jinmei Wang","doi":"10.1016/j.jfutfo.2023.07.001","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.07.001","url":null,"abstract":"<div><p>Bone loss and deterioration of bone microarchitecture would increase the bone fragility and fracture risk, leading to the osteoporosis. More and more evidences proved that plant-derived polysaccharides could have a remarkable influence on osteoblasts and osteoclasts, exerting anti-osteoporosis effects. According to the previous research, the extract of <em>Cibotium barumoz, Achyranthes bidentata, Curculigo orchioides, Epimedium brevicornum, Angelica sinensis, Polygonatum sibiricum, Dendrobium officinale, Morinda officinalis, Nelumbo nucifera, Diospyros kaki, Hordeum vulgare, Cistanche deserticola, Commiphora Myrrha</em> and other plant-derived polysaccharides could benefit to the osteoblasts and osteoclasts. The essential mechanisms are mainly related to the activation or inhibition of many factors, including runt-related transcription factor 2 (Runx2), <em>β</em>-catenin, osterix (Osx), activator protein-1 (AP-1), osteocalcin (OCN/BGP), alkaline phosphatase (ALP), osteopontin (OPN), bone morphogenetic protein (BMP), phosphatidylinositol 3-kinase (PI3K)/C-Jun N-terminal kinase (JNK)/extracellular regulated protein kinase (ERK), osteoprotegerin (OPG), receptor activator of nuclear factor-κB (RANK), monocyte/macrophage colony-stimulating factor (M-CSF), tumor necrosis factor receptor-associated factor 6 (TRAF-6), receptor activator of nuclear factor (NF)-κB ligand (RANKL), nuclear factor of activated T cells 1 (NFATc1), c-Fos, matrix metallopeptidase-9 (MMP-9), glycogen synthase kinase 3β (GSK3β)/<em>β</em>-catenin, nuclear factor E2-related factor 2 (Nrf2), as well as these related pathways, such as Wnt/β-catenin, BMP-2/SMAD1/5/8, PI3K/AKT, OPG/RANKL/RANK, NF-κB, MAPKs, etc. These plant-derived polysaccharides could improve the dynamic balance of bone formation and resorption through promoting the differentiation and maturation of osteoblast or inhibiting its formation. The reviewed plant-derived polysaccharides and their regulating mechanisms on the osteoclasts and osteoblasts provide the evidences for the development of osteoporosis therapeutics.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"4 3","pages":"Pages 183-192"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49891705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review of the interaction between diet composition and gut microbiota and its impact on associated disease","authors":"Zhaoxi Liu ,&nbsp;Meihua Liu ,&nbsp;Jing Meng ,&nbsp;Lushan Wang ,&nbsp;Min Chen","doi":"10.1016/j.jfutfo.2023.07.004","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.07.004","url":null,"abstract":"<div><p>Dietary intake has an impact on the development of gut microbiota. Humans require carbohydrates, protein, fat, and other nutrients on a daily basis to provide energy for the growth, maintenance, and repair of body tissues. These nutrition-induced changes in gut microbiota may be used to alter host physiology, including disease development and progression, such as obesity and diabetes. More research is needed to fully understand how diet influences microbiota and how microbiota influence host health. The pathways of carbohydrate, protein, and fat metabolism, as well as their interactions and regulatory mechanisms, are described in this review, as well as how diet shapes the microbiota, how dietary-microbiome crosstalk may affect disease development and progression, and how this information could be used to maintain intestinal health.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"4 3","pages":"Pages 221-232"},"PeriodicalIF":0.0,"publicationDate":"2023-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49891714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional food, modern food and nutritional value of Sea buckthorn (Hippophae rhamnoides L.): a review","authors":"Aruhan Chen ,&nbsp;Xiaowei Feng ,&nbsp;Byambasuren Dorjsuren ,&nbsp;Chimedragchaa Chimedtseren ,&nbsp;Tsend-Ayush Damda ,&nbsp;Chunhong Zhang","doi":"10.1016/j.jfutfo.2023.02.001","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.02.001","url":null,"abstract":"<div><p>Sea buckthorn (<em>Hippophae rhamnoides</em> L.) is a deciduous shrub with high nutritional and therapeutic value belonging to the family sea buckthorn, rich in oleic acid, protein, amino acids and potassium and other nutrients. Sea buckthorn can also treat heart diseases, lung diseases and other diseases. This review aims to sort out the traditional sea buckthorn food and modern sea buckthorn food, and provide important reference value for manufacturers to develop and utilize sea buckthorn. In addition, it also clarifies the nutritional value of sea buckthorn, so as to provide strong support for the comprehensive utilization of sea buckthorn fruit food and the production direction of health care industry.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"3 3","pages":"Pages 191-205"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49865408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The hypoglycemic effect of Lagerstroemia indica L. and Lagerstroemia indica L. f. alba (Nichols.) Rehd. in vitro and in vivo","authors":"Meifang Chang ,&nbsp;Adel F. Ahmed ,&nbsp;Lili Cui","doi":"10.1016/j.jfutfo.2023.02.008","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.02.008","url":null,"abstract":"<div><p><em>Lagerstroemia indica</em> L. has a high medicinal value, its bark, leaves and flowers can be used as medicine. Its flowers are reddish, purple, or white, thereinto, the white one is called <em>L. indica</em> Linn. f. <em>alba</em> (Nichols.) Rehd., which is a forma of <em>L. indica</em>. In this paper, the hypoglycemic effects of different extracts from flowers of <em>L. indica</em> (LIF) and <em>L. indica</em> L. f. <em>alba</em> (Nichols.) Rehd. (LIAF) were investigated by <em>α</em>-glucosidase inhibitory method <em>in vitro</em> and alloxan-induced diabetic mice model <em>in vivo</em>, respectively. The results <em>in vitro</em> showed that ethyl acetate extracts (EA) of LIF and LIAF (IC₅₀ = 4.45 and 4.09 µg/mL, resepectively) had the highest inhibitory activity of <em>α</em>-glucosidase, and followed by <em>n-</em>butyl alcohol extracts (BU) (IC₅₀ = 17.01 and 14.58 µg/mL, respectively), and the last was petroleum ether extracts (PE) (IC₅₀ = 103.29 and 112.47 µg/mL, respectively), the activities of all extracts were higher than that of the positive control (acarbose, IC₅₀ = 1 278.83 µg/mL). The results <em>in vivo</em> showed that compared with the model control group, each dose group of LIF could significantly (<em>P</em> &lt; 0.05, <em>P</em> &lt; 0.01 or <em>P</em> &lt; 0.001) decrease fasting blood glucose, total cholesterol (TC) level and malondialdehyde (MDA) content in diabetic mice and increase superoxide dismutase (SOD) level (<em>P</em> &lt; 0.05) in serum. Partial dose groups of LIF could significantly (<em>P</em> &lt; 0.05) decrease postprandial blood glucose, triglyceride (TG) and increase liver glycogen content. Each dose group of LIAF could significantly (<em>P</em> &lt; 0.05, <em>P</em> &lt; 0.01 or <em>P</em> &lt; 0.001) decrease fasting blood glucose, TC level and increase SOD level in serum. Partial dose groups of LIAF could significantly (<em>P</em> &lt; 0.05) decrease TG, MDA level and increase liver glycogen content. These results indicate that LIF and LIAF had effective prevention and treatment effects on the development for diabetes.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"3 3","pages":"Pages 273-277"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49866121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring phytochemicals of Withania somnifera from different vicinity for functional foods","authors":"Pooja Dhama ,&nbsp;Xianting Ding ,&nbsp;Alok Sharma","doi":"10.1016/j.jfutfo.2023.02.010","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.02.010","url":null,"abstract":"<div><p>The well-known relation between food and bioactives explores the great prospective of innovative and novel food to maintain or improve health, increasing the demand investigating advance products with medicinal effect. <em>Withania somnifera</em> also known as ‘Ashwagandha’ in India, is one of the most utilized plants in different ancient medicine systems. The present work is an effort to develop a knowledge-based concept and a quality control approach for the development of functional foods. The study took into account the standardization criteria and examined how different geographies or different field sites (of India) would influence the phytoconstituents and their distribution in the different samples of <em>W. somnifera</em>. Phytoconstituents level were strongly influenced by soil quality, cultivar, and growing season. An increase in phenolic content, flavonoid content, antioxidants and the quality yield, were all correlated with increased phytoconstituent concentrations. The highest hydro-methanolic extract yield (by reflux (Soxhlet), sonication (20 min) and maceration (16 h) was from the sample collected from Rajasthan (18.61%, <em>m</em>/<em>m</em>) followed by West Bengal (11.21%) and Madhya Pradesh (12.67%) respectively. The methanolic extract of Rajasthan sample (produced by the reflux (Soxhlet) extraction method) had the highest concentrations of flavonoids (65.32 mg quercetin equivalent (QE)/g) and the total phenols (60.35 mg gallic acid equivalent (GAE)/g), while Madhya Pradesh sample (distilled water reflux (Soxhlet)) extract had the highest antioxidant content (74.13 %). High performance thin layer chromatography (HPTLC) method was also utilized for identification of withanolides A. Chromatographic separations were carried out using <em>V</em>(ethyl acetate):<em>V</em>(toluene): <em>V</em>(acetic acid) = 9.1:1:0.6 as the mobile phase. The gas chromatograph-mass spectrometer (GC-MS) study of hydro-methanolic Soxhlet extract of <em>W. somnifera</em> from 3 different regions of India was done and the total phytochemical substances identified were 132 in sample from Rajasthan, 107 in sample from West Bengal, and 164 in sample from Madhya Pradesh respectively. To conclude, the present study demonstrates how, within a framework of integrated agricultural practices, yield and phytochemicals merge into a new paradigm of functional foods.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"3 3","pages":"Pages 278-287"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49866117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Review on herbal tea as a functional food: classification, active compounds, biological activity, and industrial status","authors":"Yuchao Liu ,&nbsp;Chunyan Guo ,&nbsp;Erhuan Zang ,&nbsp;Ruyu Shi ,&nbsp;Qian Liu ,&nbsp;Min Zhang ,&nbsp;Keyong Zhang ,&nbsp;Minhui Li","doi":"10.1016/j.jfutfo.2023.02.002","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.02.002","url":null,"abstract":"<div><p>Most herbal tea infusions use edible medicinal plants as raw material and are consumed daily. Although herbal tea has a long history of health care applications worldwide, there is a lack of systematic research on the classification and functional nutritional value of various herbal teas. In recent years, the discovery of the rich biological activities and health benefits of herbal tea has become a driving force for researchers interested in its development as a functional food. However, the shortcomings of herbal tea products are not fully known. In particular, the quality evaluation system is not perfect, and there is insufficient data on the mechanism of action of herbal teas in their traditional uses. To better understand the functions and mechanisms of various herbal teas, this article reviews the classification, effective chemical composition, main biological activities, and mechanism of action of herbal teas. Finally, the current advantages, limitations, and direction of future development of herbal tea are determined and discussed.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"3 3","pages":"Pages 206-219"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49866112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on the application, phytochemistry and pharmacology of Polygonatum odoratum, an edible medicinal plant","authors":"Jingyi Bi ,&nbsp;Huiyong Fang ,&nbsp;Jianyun Zhang ,&nbsp;Litao Lu ,&nbsp;Xian Gu ,&nbsp;Yuguang Zheng","doi":"10.1016/j.jfutfo.2023.02.006","DOIUrl":"https://doi.org/10.1016/j.jfutfo.2023.02.006","url":null,"abstract":"<div><p><em>Polygonatum odoratum</em> is distributed in several countries around the world as a medicinal and dual-use plant, and its rhizomes are used in China as a traditional Chinese medicine, also as vegetables, foods, functional foods or tea, with a history of application for more than 2 000 years, with precise efficacy and no toxic side effects. However, few reviews are published on its chemical composition and its pharmacological effects. There are many components of <em>P. odoratum</em>, including steroidal saponins, homoisoflavanones, isoflavones, flavonoids, alkaloids, lignin, volatile oil, polysaccharides and lectins. In this review, recent advances of the history and consumption of <em>P. odoratum</em>, the types of chemical components, and the pharmacological effects manifested in antitumour and anticancer, antioxidant, slowing senescence, relieving fatigue and immune regulation are summarized and discussed. Presumably, the main active ingredients of the plant are homoisoflavanones, polysaccharides, saponins, and lectins. The review provides a reference for its development and utilization in the field of functional food and medicine in the future.</p></div>","PeriodicalId":100784,"journal":{"name":"Journal of Future Foods","volume":"3 3","pages":"Pages 240-251"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49866115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}