Journal of Cartilage & Joint Preservation最新文献

{"title":"Platelet-rich plasma induced healing of a chronic osteochondral defect of the knee","authors":"Michael R. Baria ,&nbsp;Ryan Barnes ,&nbsp;David Flanigan ,&nbsp;Christopher Kaeding","doi":"10.1016/j.jcjp.2023.100132","DOIUrl":"10.1016/j.jcjp.2023.100132","url":null,"abstract":"<div><h3>Introduction</h3><p>Platelet-rich plasma (PRP) has increasingly been used in sports medicine to promote tissue healing. No previous study has demonstrated the effect of PRP alone for treatment of osteochondral defects of the knee.</p></div><div><h3>Case presentation</h3><p>We describe the case of a 37-year-old male who was diagnosed with osteochondritis dissecans of the medial femoral condyle in 2000. At that time, he underwent arthroscopic repair. In 2018, he presented for increased medial knee pain and catching. He elected to proceed with an initial PRP injection in 2018 and returned for 3 more injections through 2021. After the 4 injections, magnetic resonance imaging (MRI) demonstrated interval healing of the osteochondral defect with markedly smaller dimensions than the original 2018 MRI [0.7 cm × 0.5 cm].</p></div><div><h3>Conclusion</h3><p>To our knowledge, this is the first case of MRI-proven healing of an osteochondral defect with PRP (without accompanying cartilage restoration surgery). Ongoing treatment with an anabolic therapy like PRP may facilitate symptom improvement and structural healing.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100132"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000379/pdfft?md5=b58d595182e70ded7deca747607594f3&pid=1-s2.0-S2667254523000379-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123828638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A gap-filling, regenerative implant for open-wedge osteotomy","authors":"Margot Rikkers ,&nbsp;H. Chien Nguyen ,&nbsp;Nasim Golafshan ,&nbsp;Mylène de Ruijter ,&nbsp;Riccardo Levato ,&nbsp;Lucienne A. Vonk ,&nbsp;Nienke van Egmond ,&nbsp;Miguel Castilho ,&nbsp;Roel J.H. Custers ,&nbsp;Jos Malda","doi":"10.1016/j.jcjp.2023.100117","DOIUrl":"10.1016/j.jcjp.2023.100117","url":null,"abstract":"<div><h3>Introduction</h3><p>In patients suffering from unilateral osteoarthritis in the knee, an osteotomy can provide symptomatic relief and postpone the need for replacement of the joint. Nevertheless, open-wedge osteotomies (OWOs) around the knee joint face several challenges like postoperative pain and bone nonunion.</p></div><div><h3>Objectives</h3><p>In this study, the aim was to design, fabricate, and evaluate a gap-filling implant for OWO using an osteoinductive and degradable biomaterial.</p></div><div><h3>Methods</h3><p>Design of porous wedge-shaped implants was based on computed tomography scans of cadaveric legs. Implants were 3-dimensionally printed using a magnesium strontium phosphate-polycaprolactone (MgPSr-PCL) biomaterial ink. Standardized scaffolds with different inter-fiber spacing (IFS) were mechanically characterized and osteoinductive properties of the biomaterial were assessed in vitro. Finally, human-sized implants with different heights (5 mm, 10 mm, 15 mm) were designed and fabricated for ex vivo implantation during 3 OWO procedures in human cadaveric legs.</p></div><div><h3>Results</h3><p>Implants printed with an interior of IFS-1.0 resulted in scaffolds that maintained top and bottom porosity, while the interior of the implant exhibited significant mechanical stability. Bone marrow concentrate and culture expanded mesenchymal stromal cells attached to the MgPSr-PCL material and proliferated over 21 days in culture. The production of osteogenic markers alkaline phosphatase activity, calcium, and osteocalcin was promoted in all culture conditions, independent of osteogenic induction medium. Finally, 3 OWO procedures were planned and fabricated wedges were implanted ex vivo during the procedures. A small fraction of one side of the wedges was resected to assure fit into the proximal biplanar osteotomy gap. Preplanned wedge heights were maintained after implantation as measured by micro-computed tomography.</p></div><div><h3>Conclusion</h3><p>To conclude, personalized implants for implantation in OWOs were successfully designed and manufactured. The implant material supported osteogenesis of mesenchymal stromal cells and bone marrow concentrate in vitro and full-size implants were successfully implemented into the surgical procedure without compromising preplanned wedge height.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100117"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000197/pdfft?md5=a5e4085339c07797afaa60e8703f80de&pid=1-s2.0-S2667254523000197-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133335155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osteochondral allograft and xenograft immunogenicity decrease following ex vivo tissue culture","authors":"Kate E. Birdwhistell ,&nbsp;Samuel P. Franklin ,&nbsp;David J. Hurley ,&nbsp;Bradley D. Heins ,&nbsp;John F. Peroni","doi":"10.1016/j.jcjp.2023.100115","DOIUrl":"10.1016/j.jcjp.2023.100115","url":null,"abstract":"<div><h3>Introduction/Objective</h3><p>Osteochondral allografting can be an effective option for the treatment of focal cartilage injuries. However, wide scale applicability of this technique is limited by availability of donor tissue. To overcome this limitation, osteochondral xenografting has been proposed as a potential alternative, but immune-mediated rejection precludes its clinical application at this time. We hypothesized that removing much of the marrow cell content through tissue culture would result in a decrease in xenograft immunogenicity. We believed this could be tested in a preclinical animal model.</p></div><div><h3>Methods</h3><p>Fresh porcine femoral condyles were harvested and cultured for 0, 14, or 28 days before coculture with either allogeneic enriched porcine T-cells or xenogeneic enriched equine T-cells for 5 days. After 5 days, these cocultures were pulsed with 5-ethynyl-2′deoxyuridine then analyzed by flow cytometry to assess the level of cell proliferation. Coculture supernatant samples were also collected to evaluate the levels of prostaglandin-E2 and monocyte chemotactic protein-1 (MCP-1) as markers of inflammation.</p></div><div><h3>Results</h3><p>The osteochondral tissue induced significantly less T-cell proliferation, prostaglandin-E2, and MCP-1 production when the tissue had been cultured for either 14 or 28 days prior to the coculture assay (<em>P</em> &lt; .0001).</p></div><div><h3>Conclusions</h3><p>We conclude that T-cell responses to either allogeneic or xenogeneic osteochondral tissues were significantly reduced by 14 days of preculture prior to exposure to T-cells.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100115"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000173/pdfft?md5=08e4533d0f9ff6b3ca8661fb07facc17&pid=1-s2.0-S2667254523000173-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123805830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Noninferiority meta-analysis of autologous vs allogeneic osteochondral transplantation for the treatment of osteochondral defects of the knee confounded by defect size differences","authors":"Dexter Seow ,&nbsp;Jin Hean Koh ,&nbsp;Hannah L.X. Cheang ,&nbsp;Gin Way Law ,&nbsp;Glenys Poon ,&nbsp;Li Yi Tammy Chan ,&nbsp;Keng Lin Wong ,&nbsp;James Hui","doi":"10.1016/j.jcjp.2023.100130","DOIUrl":"10.1016/j.jcjp.2023.100130","url":null,"abstract":"<div><h3>Background</h3><p>Autologous and allogeneic osteochondral transplantations are widely employed for knee osteochondral defects (OCDs). However, there has been a lack of consensus on the efficacy of autografts vs allografts.</p></div><div><h3>Objectives</h3><p>To evaluate the complication profile following autologous vs allogeneic osteochondral transplantation for knee OCDs.</p></div><div><h3>Data sources</h3><p>PubMed and Embase.</p></div><div><h3>Study eligibility criteria, participants, and interventions</h3><p>Clinical studies that reported complication rates following autologous or allogeneic osteochondral transplantation for knee OCDs.</p></div><div><h3>Study appraisal and synthesis methods</h3><p>Meta-analysis of proportions using the restricted maximum-likelihood method after the Freeman-Tukey double-arcsine transformation.</p></div><div><h3>Results</h3><p>There were 35 studies with 2647 and 2569 OCDs included before and after lost to follow-up, respectively. Graft failure rates were not significantly lower in autografts vs allografts in all analyses: as reported (6.23% vs 10.81%, respectively; <em>P = .</em>63), best-case (6.00% vs 10.24%, respectively; <em>P = .</em>66) and worst-case analyses (7.46% vs 14.43%, respectively; <em>P = .</em>42). In the subgroup of mean follow-up time &lt;36 months, graft failure rates were significantly lower in autografts vs allografts in all analyses.</p></div><div><h3>Limitations</h3><p>The meta-analysis was confounded by the inherent differences in mean defect sizes of the autograft and allograft arms.</p></div><div><h3>Conclusions and implications of key findings</h3><p>Overall graft failure and revision rates were lower in autograft vs allograft for the treatment of knee OCDs but this may have been confounded by the inherent differences in mean defect sizes between the groups. Further studies on autografts for larger-sized knee OCDs and allografts for smaller-sized knee OCDs are warranted to better complete the noninferiority analysis.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100130"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000355/pdfft?md5=d2c4758f20fadca93f223a29858e8078&pid=1-s2.0-S2667254523000355-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121672449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Welcome to the final issue of the Journal of Cartilage & Joint Preservation in 2023","authors":"Miranda Manfre,&nbsp;Rachel M. Frank","doi":"10.1016/j.jcjp.2023.100156","DOIUrl":"10.1016/j.jcjp.2023.100156","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100156"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000628/pdfft?md5=a4fac3f17d314cdb3396ba6ffead50b3&pid=1-s2.0-S2667254523000628-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135663638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Destabilization of the medial meniscus to induce post-traumatic osteoarthritis in domestic pigs","authors":"Jacqueline M. Chevalier ,&nbsp;Garett B. Pearson ,&nbsp;Nicole Nixon ,&nbsp;Carl R. Flannery ,&nbsp;Luis Campoy ,&nbsp;Lisa A. Fortier","doi":"10.1016/j.jcjp.2023.100139","DOIUrl":"10.1016/j.jcjp.2023.100139","url":null,"abstract":"<div><h3>Introduction</h3><p>Post-traumatic osteoarthritis (PTOA) develops following traumatic articular insult. One model system used to study the progression and treatment of PTOA is the destabilization of the medial meniscus (DMM) as first described by Glasson et al performed in mini-pigs. Miniature pigs are less available, more expensive, and have synovial fluid sampling limitations, limiting the availability of osteoarthritis biomarkers compared to domestic pigs.</p></div><div><h3>Objectives</h3><p>The following technical note details stepwise procedures and animal welfare strategies for the use of Yorkshire pigs as a large animal PTOA model.</p></div><div><h3>Methods</h3><p>The following technical note details stepwise procedures to perform peroperative saphenous nerve block, DMM, and subsequent postoperative management in Yorkshire pigs as a large animal PTOA model.</p></div><div><h3>Results</h3><p>At 4 weeks post-operatively, all pigs develop mild-moderate PTOA based on postmortem joint dissections.</p></div><div><h3>Conclusions</h3><p>This technical note provides further details on the arthrotomy approach to destabilize the medial meniscus of domestic pigs as a model of PTOA.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100139"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000458/pdfft?md5=ea8f7ca097b21496005ddfbe36c38f6f&pid=1-s2.0-S2667254523000458-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129909528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complement system dysregulation in synovial fluid from patients with persistent inflammation following anterior cruciate ligament reconstruction surgery","authors":"Laura E. Keller ,&nbsp;Lisa A. Fortier ,&nbsp;Christian Lattermann ,&nbsp;Emily R. Hunt ,&nbsp;Sheng Zhang ,&nbsp;Qin Fu ,&nbsp;Cale A. Jacobs","doi":"10.1016/j.jcjp.2023.100114","DOIUrl":"10.1016/j.jcjp.2023.100114","url":null,"abstract":"<div><h3>Introduction</h3><p>Patients with anterior cruciate ligament injury are at high risk of posttraumatic osteoarthritis and their response to reconstructive surgery and rehabilitation vary. Proteins identified in the orchestration of the acute inflammatory response may be predictive of patient outcomes.</p></div><div><h3>Objective</h3><p>An unbiased, bottom-up proteomics approach was used to discover novel targets for therapeutics in relation to dysregulation in the orchestration of inflammatory pathways implicated in persistent joint inflammation subsequent to joint trauma.</p></div><div><h3>Methods</h3><p>Synovial fluid was aspirated from patients at 1 week and 4 weeks after anterior cruciate ligament reconstruction (ACLR) and interleukin 6 (IL-6) concentrations were quantified by enzyme-linked immunosorbent assay. Patients were segregated into IL-6^low and IL-6^high groups based on IL-6 concentrations in synovial fluid at 4-weeks postoperation and proteins in synovial fluid were analyzed using qualitative, bottom-up proteomics. Abundance ratios were calculated for IL-6^high and IL-6^low groups as 4 weeks postoperation:1 week postoperation.</p></div><div><h3>Results</h3><p>A total of 291 proteins were detected in synovial fluid, 34 of which were significantly (<em>P</em> &lt; .05) differentially regulated between groups. Proteins associated with the classical and alternative complement cascade pathways were increased in the IL-6^high compared to IL-6^low group. Insulin-like growth factor-binding protein 6 (IGFBP-6) was increased by nearly 60-fold in the IL-6^low group.</p></div><div><h3>Conclusions</h3><p>Patients segregated by IL-6 concentration in synovial fluid at 4 weeks post-ACLR demonstrated differential regulation of multiple pathways, providing opportunities to investigate novel targets, such as IGFBP-6, and to take advantage of therapeutics already approved for clinical use in other diseases that target inflammatory pathways, including the complement system.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 4","pages":"Article 100114"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2667254523000161/pdfft?md5=4a1cd353ab3f882cecab891d47eee8b1&pid=1-s2.0-S2667254523000161-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114652860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Force plate testing is correlated with jumping performance in elite Nordic skiers","authors":"Kinjal D. Vasavada ,&nbsp;Dhruv S. Shankar ,&nbsp;Charles C. Lin ,&nbsp;Nicole D. Rynecki ,&nbsp;Amanda Avila ,&nbsp;Scott Buzin ,&nbsp;Andrew L. Chen ,&nbsp;Cordelia W. Carter ,&nbsp;Lauren E. Borowski ,&nbsp;Heather A. Milton ,&nbsp;Guillem Gonzalez-Lomas","doi":"10.1016/j.jcjp.2023.100144","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100144","url":null,"abstract":"<div><h3>Introduction</h3><p>Ski jumping (SJ) and Nordic combined (NC) athletes are at higher risk for femoroacetabular impingement (FAI) compared to the general population.</p></div><div><h3>Objectives</h3><p>The purpose of this study was to determine the relationship between force plate testing metrics, Functional Movement Screen (FMS) scores, and radiographic signs of FAI and SJ performance.</p></div><div><h3>Methods</h3><p>Elite SJ and NC athletes were prospectively recruited. FMS testing was performed to assess muscular imbalance, instability, and immobility. Vertical jump testing was performed using a commercially available force plate device. Ski jump score and distance score were measured on a single jump for each athlete.</p></div><div><h3>Results</h3><p>Twenty-one athletes (10 SJ, 11 NC) with competition scores were included. On FMS testing, most SJ (67%) and NC (73%) athletes demonstrated core instability. There were higher rates of hip instability and ankle stiffness among SJ athletes, although not statistically significant (<em>P</em> &gt; .05). Ski jump distance score was significantly positively correlated with force plate vertical jump height, maximum acceleration, maximum velocity, concentric impulse, counter-movement depth, and flight time (<em>P</em> &lt; .05). FMS testing results and radiographic FAI were not significantly associated with competition scores.</p></div><div><h3>Conclusions</h3><p>Our results show significant positive correlations between competition scores and force plate jump testing performance as measured by jump height, acceleration, maximum velocity, counter-movement depth, and concentric impulse in elite SJ and NC athletes. Our findings suggest that ski jumpers may benefit from training that emphasizes stretch-shortening cycles and eccentric-to-concentric contraction transition, which may optimize their performance and promote joint stability.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 3","pages":"Article 100144"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49880132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concurrent meniscus and chondral injuries after anterior cruciate ligament injury are more common in elite versus recreational alpine skiers: a systematic review","authors":"Joseph Featherall ,&nbsp;Reece Rosenthal ,&nbsp;Daniel Song ,&nbsp;Natalya McNamara ,&nbsp;Travis Maak ,&nbsp;Stephen Aoki ,&nbsp;Justin Ernat","doi":"10.1016/j.jcjp.2023.100141","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100141","url":null,"abstract":"<div><h3>Background</h3><p>The anterior cruciate ligament (ACL) has been extensively studied in those with alpine skiing injuries; however, less focus has been given to meniscal/chondral injuries in this population.</p></div><div><h3>Objectives</h3><p>To perform a systematic review investigating the incidence of meniscal/chondral injuries in alpine skiers who have sustained an ACL injury.</p></div><div><h3>Data sources</h3><p>MEDLINE, Scopus, manual journal searches.</p></div><div><h3>Study eligibility criteria</h3><p>Studies reporting rates of meniscal and/or chondral injuries in alpine skiers with an ACL tear were included. Techniques, revisions, non-alpine skiers, and studies lacking an association between skiing and ACL diagnosis were excluded.</p></div><div><h3>Participants and interventions</h3><p>Alpine skiers with a diagnosis of an ACL tear.</p></div><div><h3>Study appraisal and synthesis methods</h3><p>MINORS criteria.</p></div><div><h3>Results</h3><p>Nine hundred fifty-eight studies were identified. Screening, removal of duplicates, and assessment for inclusion/exclusion criteria resulted in 12 level III/IV studies for review. A total of 1185 skiers with ACL injuries were included (209 elite and 976 recreational). Meniscal tears were present in 47.4% of the skiers, with an increased rate seen in elite versus recreational skiers (61.2% vs 43.2%). Elite skiers were more likely to have a combined medial/lateral meniscal injury and a lateral meniscal tear repair (69.8% vs 19.2% for the latter). There were no differences in medial meniscal tear treatment. Chondral injuries presented at a rate of 11.2% and were more common in elite versus recreational skiers (20.3% vs 5.3%).</p></div><div><h3>Limitations</h3><p>Heterogenous nature of study types included; Did not include larger databases and was limited to alpine skiing studies only; demographics were not part of the analysis.</p></div><div><h3>Conclusions</h3><p>Approximately 47% of the alpine skiers with an ACL injury sustained a concomitant meniscal tear, with 11% having an associated chondral injury. Meniscal/chondral injuries are more common in elite skiers, and they are more likely to have their meniscus repaired.</p></div><div><h3>Implications of key findings</h3><p>Careful consideration of the accompanying pathology is warranted in alpine skiers who present with ACL injury.</p></div><div><h3>Systematic review registration number</h3><p>PROSPERO: CRD42022373207.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 3","pages":"Article 100141"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49880135","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiligament knee injuries in winter sports athletes","authors":"Matthew P. Corsi ,&nbsp;Adam B. Thompson ,&nbsp;Nicholas I. Kennedy ,&nbsp;Robert F. LaPrade ,&nbsp;Gilbert Moatshe","doi":"10.1016/j.jcjp.2023.100143","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100143","url":null,"abstract":"<div><p>Multiligament knee injuries (MLKIs) are severe injuries that involve complete or partial tear to multiple ligaments of the knee, such as the cruciate ligaments, collateral ligaments, as well as structures such as the posteromedial and posterolateral corners. These injuries often occur as a result of high-energy trauma in motor vehicle accidents, but can also occur during sports activities such as a fall or collision while skiing or snowboarding. Diagnosis of an MLKI can be challenging due to the multifaceted nature of these injuries, and a comprehensive evaluation, including a thorough history, physical examination, and imaging studies, is necessary. Imaging methods, such as plain and stress radiographs and magnetic resonance imaging, are often used to confirm the diagnosis and assist in the establishment of a treatment plan. Treatment of MLKIs commonly involves surgical repair or reconstruction of torn ligaments and capsular structures, followed by lengthy rehabilitation focused on mobility, strength, and improving knee function. Return to sport is a concern, especially for those with many ligaments torn and those involving both cruciate ligaments and/or those involving the posterolateral corner. Prevention of MLKIs in skiing and snowboarding is important, and proper technique, equipment, risk awareness, and strengthening exercises can help reduce the risk of injury. While much is known about knee injuries in skiers, further research is needed to better understand MLKIs in ski and snowboard athletes, including the incidence, optimal management, and return to sport rates.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 3","pages":"Article 100143"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49880129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}