Journal of Cartilage & Joint Preservation最新文献

{"title":"Guest editorial: special edition on ski and snowboarding injuries and related conditions","authors":"Alexander Golant , Michael Alaia , Brian Waterman","doi":"10.1016/j.jcjp.2023.100145","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100145","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 3","pages":"Article 100145"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49880136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracing burnout during adolescence to past sports experiences: a retrospective analysis of sport-specific antecedents among alpine ski racers","authors":"Bradley Fawver ,&nbsp;Sarah Taylor ,&nbsp;Brady S. DeCouto ,&nbsp;Rhiannon L. Cowan ,&nbsp;Keith R. Lohse ,&nbsp;A. Mark Williams ,&nbsp;Les Podlog","doi":"10.1016/j.jcjp.2023.100142","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100142","url":null,"abstract":"<div><h3>Introduction</h3><p>Previous theoretical frameworks focusing on burnout have identified numerous antecedents and psychosocial risk factors; however, the influence of early sport-specific experiences on burnout in developmental athlete populations remains less understood.</p></div><div><h3>Objectives</h3><p>We explored the associations between burnout and prior sports engagement (ie, milestones, practice time, performance, injury history) in a sample of subelite academy alpine ski racers in the United States (N = 169, M age = 15.82 ± 1.80).</p></div><div><h3>Methods</h3><p>Participants completed retrospective practice history profiles (milestones, practice time, injury), while their respective performance data were collected using an online national ranking registry. Simple and mixed-effect regressions were implemented to assess the associations between these measures and subscales of the Athlete Burnout Questionnaire.</p></div><div><h3>Results</h3><p>The results indicated that greater participation in the coach-led group and individual practice during adolescence mitigated burnout responses (ie, greater sense of accomplishment, less sport devaluation), whereas more play earlier in development was associated with greater devaluation. Furthermore, poorer performance and more injury incidences were associated with increased burnout (ie, reduced sense of accomplishment).</p></div><div><h3>Conclusions</h3><p>The structure of training and past experiences during early career years appear to influence burnout among alpine ski racing during their adolescent years, the implications of which are discussed in relation to sport developmental pipelines.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 3","pages":"Article 100142"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49880133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of orthobiologic augmentation for meniscal repairs: current concepts and future perspectives","authors":"Kazunori Shimomura ,&nbsp;George Jacob ,&nbsp;Hiroto Hanai ,&nbsp;Norimasa Nakamura","doi":"10.1016/j.jcjp.2022.100090","DOIUrl":"https://doi.org/10.1016/j.jcjp.2022.100090","url":null,"abstract":"<div><h3>Introduction</h3><p>Meniscal tissue is a complex structure and performs a vital role in the normal biomechanical functioning of the knee joint. Unfortunately, meniscal tissue lacks vascularity and therefore demonstrates poor healing potential. To improve meniscal healing biological therapies have been used to enhance meniscal repairs and improve repair outcomes. Newer therapies incorporate growth factors and mesenchymal stem cells (MSCs) to improve the probability of healing and patient treatment outcomes under the term orthobiologics.</p></div><div><h3>Objective</h3><p>To give a narrative review of orthobiologics utilized in meniscal repair therapies and determine their effectiveness and role in treating meniscal tears.</p></div><div><h3>Methods</h3><p>A literature search was conducted using the PubMed (MEDLINE) and EMBASE databases in April 2021 without any date restrictions. Any relevant literature describing orthobiologic therapies utilized in meniscal repair was identified from the clinical databases and a narrative review was undertaken.</p></div><div><h3>Results</h3><p>Currently, orthobiologics used in clinical settings are autologous platelet-rich plasma (PRP) and MSC-based therapies. These demonstrate clinical benefit and enhanced meniscal repair. Standardizing PRP remains challenging and is essential to provide uniformity in treatment. Both therapies appear safe with no significant adverse effects, and MSC-based therapies do not show any increased risk of tumorgenicity.</p></div><div><h3>Conclusion</h3><p>Orthobiologics in meniscal tears have shown mild to moderate clinical benefit, as demonstrated in a small series of clinical studies. However, literature on clinical results is scarce, and preclinical data remains the justification for these therapies. Larger, well-designed trials will determine their true benefit, and combining them with tissue engineering techniques may improve results in the future.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100090"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term results of particulated juvenile allograft cartilage implantation: a case report with eleven-year second-look arthroscopy and review of literature","authors":"Jarod A. Richards,&nbsp;Lauren M. Nelson,&nbsp;David N.M. Caborn","doi":"10.1016/j.jcjp.2023.100113","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100113","url":null,"abstract":"<div><p>High-grade osteochondral lesions cause pain, functional limitations, and oftentimes require surgical treatment. Described operative interventions include microfracture, osteochondral autograft transfers, osteochondral allograft transplantation, autologous chondrocyte implantation, and matrix assisted autologous chondrocyte implantation. Another option for recalcitrant cartilaginous defects is particulated juvenile allograft cartilage (PJAC) implantation. Short-term studies into PJAC have yielded promising results in its capacity for hyaline or hyaline-like cartilage regeneration though the long-term outcomes of this procedure are not well understood. We present a case of PJAC implementation to the medial femoral condyle in a 15-year-old female competitive soccer player with 11-year magnetic resonance imaging and arthroscopic second-look follow-up. In addition, we performed a literature review to summarize prior published PJAC outcomes data.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100113"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49883930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum biomarkers in healthy, injured, and osteoarthritic knees: a critical review","authors":"Julie P. Burland ,&nbsp;Emily R. Hunt ,&nbsp;Christian Lattermann","doi":"10.1016/j.jcjp.2022.100091","DOIUrl":"https://doi.org/10.1016/j.jcjp.2022.100091","url":null,"abstract":"<div><h3>Introduction</h3><p>Osteoarthritis (OA) can have deleterious effects on the joint. Many targeted strategies have been proposed to identify OA onset and progression prior to presentation of clinical symptoms and radiographic changes. Emerging research has focused on the utility of certain biochemical markers (biomarkers) as potential precursors of OA. Serum biomarkers have been widely studied across disease spectrums for their ability to classify the following characteristics: cartilage damage during early preradiographic stages, disease activity, severity or burden of disease, prognosis prediction, and response to certain treatment approaches. These classifications may be useful for understanding the evaluation and the qualification of biomarkers related to OA.</p></div><div><h3>Objectives</h3><p>The purpose of this critical review is to summarize and evaluate the existing serum biomarkers currently proposed for the identification and evaluation of osteoarthritis onset and progression in 3 populations: healthy-, anterior cruciate ligament reconstructed-, and osteoarthritic knees using the BIPED (burden of disease, investigative, prognostic, efficacy of intervention and diagnostic) classification.</p></div><div><h3>Methods</h3><p>Articles that reported on serum biomarkers in individuals with healthy, anterior cruciate ligament reconstructed and osteoarthritic knees were collected from peer-reviewed sources available on Medline (January 1, 2000 through March 31, 2020). Search terms included the following: serum AND biomarker AND knee AND osteoarthritis AND healthy AND (“anterior cruciate ligament” OR “anterior cruciate ligament reconstruction” OR “ACLR”). Articles were limited to studies in humans, written in English, and full text accessible. All serum biomarkers evaluated in the gathered articles were classified according to the BIPED classification.</p></div><div><h3>Results</h3><p>A total of 164 unique serum biomarkers were identified across healthy individuals, 18 reported on patients after knee injury (commonly anterior cruciate ligament reconstruction), 71 reported on patients with diagnosed osteoarthritis and 5 reported mixed populations. Biomarkers studied most frequently include serum COMP, interleukin-6, C2C, CPII, hyaluronic acid, tumor necrosis factor- alpha, c-reactive protein, MMP-3, high sensitivity-CRP, IL-8 and IL-1B, CS846, YKL-40, and C1,2C.</p></div><div><h3>Conclusions</h3><p>The results highlight large variations in how these biomarkers respond to different stimuli across multiple populations. The most frequently studied biomarkers were those categorized under the BIPED criteria as <em>diagnostic, burden of disease</em> and <em>prognostic</em> biomarkers. More robust and longitudinal research on serum biomarkers needs to be conducted in these 3 populations.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100091"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49883932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trochlear morphology in healthy people: implications for osteochondral allograft transplantation","authors":"Mitchell S. Mologne ,&nbsp;Matthew T. Provencher ,&nbsp;Annalise M. Peebles ,&nbsp;Timothy S. Mologne","doi":"10.1016/j.jcjp.2022.100097","DOIUrl":"https://doi.org/10.1016/j.jcjp.2022.100097","url":null,"abstract":"<div><h3>Introduction</h3><p>The unique anatomy of the trochlea makes osteochondral allograft (OCA) grafting of femoral trochlear lesions challenging but could be improved with better understanding of trochlear morphology.</p></div><div><h3>Objectives</h3><p>To assess trochlear width, depth, and sulcus angle via magnetic resonance imaging (MRI) in patients without patellofemoral problems and determine whether bench measurements of donor femurs can better match donors and patients.</p></div><div><h3>Methods</h3><p>An analysis was performed on 209 deidentified MRIs (average age: 25.8 years, ages 12-57). Trochlear width and depth were measured 15 mm and 20 mm distal to the most proximal articular surface. MRIs were classified into groups based on trochlear depth (Group 1: 0-4.0 mm; Group 2: 4.1-6.0 mm; Group 3: &gt;6.0 mm). Difference in depth at the 2 distances was calculated. The same protocol was performed on 23 cadaveric knees.</p></div><div><h3>Results</h3><p>Mean trochlear depths at 15 mm and 20 mm were significantly different between groups. Group 3 had significantly larger trochlear widths than Groups 1 and 2. All MRIs showed an increase in trochlear depth between 15 and 20 mm (mean increase: 1.31 ± 0.78 mm). There was no significant difference in trochlear depths between MRI and cadaveric groups. For MRI groups at 15 mm, the resultant apex decreased 10° between Groups 1 and 2 and 7.4° between Groups 2 and 3.</p></div><div><h3>Conclusions</h3><p>Assuming trochleae are perfect isosceles triangles, one can measure trochlear width and cartilage sulcus angle via MRI to assess trochlear depth. Consideration of trochlear depth and its distribution may enable more accurate matching of OCAs.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100097"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does the tidemark location matter in osteochondral allograft transplantation? A finite element analysis","authors":"Amit K. Manjunath,&nbsp;Martin Pendola,&nbsp;Eoghan T. Hurley,&nbsp;Charles C. Lin,&nbsp;Laith M. Jazrawi,&nbsp;Michael J. Alaia,&nbsp;Eric J. Strauss","doi":"10.1016/j.jcjp.2022.100092","DOIUrl":"https://doi.org/10.1016/j.jcjp.2022.100092","url":null,"abstract":"<div><h3>Introduction</h3><p>While OCA has been shown to result in good long-term outcomes, there is still a considerable failure rate present with room for improvement.</p></div><div><h3>Objectives</h3><p>The purpose of this study is to evaluate the impact that osteochondral allograft cartilage thickness has on contact pressures, and to simulate whether a mismatch of the subchondral bony interface relative to the host-recipient site results in altered biomechanics.</p></div><div><h3>Methods</h3><p>Properties of articular cartilage and bone were incorporated into a finite element model to create a simulated osteochondral lesion (diameter: 10 mm, height: 10 mm, cartilage thickness: 2 mm, subchondral bone thickness: 8 mm). Five osteochondral plugs were constructed to fill the defect, with cartilage-to-bone ratios between 1:9 and 1:1. The plugs were inserted and given a static downward force of 5000 N. Resultant stresses and displacements were measured.</p></div><div><h3>Results</h3><p>The 2:8 cartilage-to-bone ratio plug, matched with the recipient site, was deemed optimal based on its resultant stress and displacement. The 1:9 plug displaced less than the 2:8 match and endured greater stress per unit of cartilage volume, whereas the 3:7 plug also displayed similar displacement to the 1:9 plug but had greater cartilage volume and was able to distribute less stress per unit of cartilage volume. The 4:6 plug displaced to a similar extent as the 3:7 plug but displayed a unique pattern of strain. The 5:5 plug was considered nonfunctional, as the majority of displacement was seen in the cartilage of the recipient site rather than in the plug itself.</p></div><div><h3>Conclusions</h3><p>The relationship between the cartilage-to-bone ratio in osteochondral allografts and that of their surroundings significantly impacts the distribution of stresses and predilection for micromotion at the repair site.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100092"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel method for the preparation and frozen storage of growth factors and cytokines obtained from platelet-rich plasma","authors":"Irina Brokhman,&nbsp;Anthony M. Galea","doi":"10.1016/j.jcjp.2022.100089","DOIUrl":"https://doi.org/10.1016/j.jcjp.2022.100089","url":null,"abstract":"<div><p>Platelet-rich plasma (PRP) therapy is employed to treat damaged connective tissues and osteoarthritis. PRP is collected in the presence of an anticoagulant to avoid premature activation. The PRP is then activated by various activation methods that all have regulatory or cost drawbacks. Additionally, activated PRP can only be stored for a limited time. The purpose of this study was to assess the biological stability of a PRP composition obtained from platelets of healthy volunteers using a mechanical activation by passing PRP through a 0.22 µm filter and stored for up to 9 months. The PRP fraction was isolated and then activated using either mechanical or thrombin techniques: 9 samples were evaluated in each experiment. The concentrations of interleukin (IL)-4, IL-10, IL-13, platelet-derived growth factor, transforming growth factor beta 1, insulin-like growth factor 1, and vascular endothelial growth factor were compared in samples that were freshly collected and samples that were previously stored at −80 °C for 9 months. Protein concentration analysis showed no statistically significant differences in the composition of the PRP when the platelets were activated by thrombin or mechanical activation. There was also no statistically significant difference in the concentration of cytokines and growth factors in the PRP autologous composition after storage for 9 months at −80 °C. Mechanical activation is an efficient method to activate PRP, and the PRP-derived autologous composition is capable of being stored for up to 9 months without affecting the concentration of the analyzed proteins.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100089"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transtibial single-tunnel all-inside technique for repair of a complete radial meniscal tear","authors":"Amar S. Vadhera ,&nbsp;Suhas P. Dasari ,&nbsp;Hasani W. Swindell ,&nbsp;Kevin C. Parvaresh ,&nbsp;Nikhil N. Verma ,&nbsp;Robert F. LaPrade ,&nbsp;Jorge Chahla","doi":"10.1016/j.jcjp.2022.100075","DOIUrl":"https://doi.org/10.1016/j.jcjp.2022.100075","url":null,"abstract":"<div><h3>Introduction</h3><p>Radial meniscus tears significantly compromise knee biomechanics due to loss of the circumferential fiber connections and have been shown to be biomechanically equivalent to a total meniscectomy. There is a paucity of data regarding the biomechanical performance of radial meniscal repairs and numerous technical challenges associated with surgical repair. Further, current repair methods have been shown to lead to high rates of incomplete, nonanatomical healing of the meniscus and can potentially cause progressive joint degeneration and osteoarthritis. This is particularly true for the avascular portions of the meniscus. As a result, such injuries have been historically treated with a partial meniscectomy. There has been a growing interest in transtibial repair mechanisms as a potential solution to this challenging pathology.</p></div><div><h3>Objectives</h3><p>The purpose of this technical note is to detail a method for repairing a complete radial tear of the medial meniscus using a single-tunnel transtibial technique.</p></div><div><h3>Methods</h3><p>After a thorough history and clinical examination, and imaging, the patient was diagnosed with a complex medial meniscal tear with a primary radial tear component. A single tunnel transtibial meniscal repair was indicated and performed.</p></div><div><h3>Results</h3><p>An anatomic repair was achieved with tension across the defect. The patient successfully returned to activities.</p></div><div><h3>Conclusions</h3><p>Single-tunnel transtibial repairs of radial tears in the meniscus may provide increased stability by anchoring the meniscal leaflets to the tibia as well as a potential biological benefit by releasing growth factors and progenitor cells from the bone marrow.</p></div>","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100075"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49883931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Welcome to the second JCJP issue of 2023","authors":"Rachel M. Frank","doi":"10.1016/j.jcjp.2023.100131","DOIUrl":"https://doi.org/10.1016/j.jcjp.2023.100131","url":null,"abstract":"","PeriodicalId":100760,"journal":{"name":"Journal of Cartilage & Joint Preservation","volume":"3 2","pages":"Article 100131"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}