JOS Case Reports最新文献_第3页

Spinal meningeal melanocytoma with extensive dura mater pigmentation: Review of meningeal melanocytic tumors with GNAQ mutations 伴有广泛硬脑膜色素沉着的脊膜黑素细胞瘤：伴有GNAQ突变的脊膜黑素细胞瘤的研究综述

JOS Case Reports Pub Date : 2025-06-01 Epub Date: 2024-11-06 DOI: 10.1016/j.joscr.2024.10.001

Kazumichi Yagura , Shu Takahashi , Kazuyuki Segami , Yusuke Oshita , Genshu Tate , Koji Kanzaki , Tomoaki Toyone , Yoshifumi Kudo

{"title":"Spinal meningeal melanocytoma with extensive dura mater pigmentation: Review of meningeal melanocytic tumors with GNAQ mutations","authors":"Kazumichi Yagura , Shu Takahashi , Kazuyuki Segami , Yusuke Oshita , Genshu Tate , Koji Kanzaki , Tomoaki Toyone , Yoshifumi Kudo","doi":"10.1016/j.joscr.2024.10.001","DOIUrl":"10.1016/j.joscr.2024.10.001","url":null,"abstract":"<div><h3>Background</h3><div>Meningeal melanocytoma is an extremely rare benign tumor. Although gross total resection of the tumor is the most effective therapy, consensus regarding the management of adjacent pigmented dura mater is lacking. Here, we present a case of meningeal melanocytoma with extensive dura mater pigmentation and discuss the importance of <em>GNAQ</em> mutations in making the diagnosis.</div></div><div><h3>Case presentation</h3><div>A 37-year-old woman presented with bilateral leg weakness. Magnetic resonance imaging revealed a thoracic intradural extramedullary mass. A solid blackish tumor wrapped in dark-pigmented dura mater was excised. No neoplasms were detected in the dura mater or on cerebrospinal fluid analysis. Genetic analysis revealed a <em>GNAQ</em> mutation. The mass was diagnosed as a meningeal melanocytoma. No recurrence was observed during 2 years of follow-up.</div></div><div><h3>Conclusions</h3><div>Histopathological analysis of the dura mater and cytological analysis of the cerebrospinal fluid is useful for deciding whether to administer adjuvant therapy.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 2","pages":"Pages 48-52"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteochondral fragment fixation for Freiberg's disease: A report of three cases 骨软骨碎片固定治疗Freiberg病3例报告

JOS Case Reports Pub Date : 2025-06-01 Epub Date: 2024-11-25 DOI: 10.1016/j.joscr.2024.11.001

Ryo Fukagawa , Ichiro Yoshimura , Tomonobu Hagio , Tetsuro Ishimatsu , Yuki Sugino , Seiya Tomonaga , Yoshimasa Taniguchi , Takuaki Yamamoto

{"title":"Osteochondral fragment fixation for Freiberg's disease: A report of three cases","authors":"Ryo Fukagawa , Ichiro Yoshimura , Tomonobu Hagio , Tetsuro Ishimatsu , Yuki Sugino , Seiya Tomonaga , Yoshimasa Taniguchi , Takuaki Yamamoto","doi":"10.1016/j.joscr.2024.11.001","DOIUrl":"10.1016/j.joscr.2024.11.001","url":null,"abstract":"<div><h3>Background</h3><div>Freiberg's disease is characterized by osteonecrosis of the metatarsal head and is most common in teenage girls who play sports. Various treatment options are selected depending on the disease progression. When conservative measures fail, dorsiflexion osteotomy or osteochondral grafting are often performed. However, each approach has its drawbacks. Herein, we present three cases in which Freiberg's disease was effectively managed with osteochondral fragment fixation, circumventing the limitations associated with traditional treatment methods.</div></div><div><h3>Case presentation</h3><div>We describe three teenagers with Frieberg's disease who failed to respond to conservative treatment. The osteochondral fragment was stabilized using absorbable pins, thereby preserving the articular cartilage and maintaining the joint congruity. All three patients achieved substantial pain relief and functional improvement postoperatively.</div></div><div><h3>Conclusion</h3><div>Osteochondral fragment fixation is a promising alternative for the management of Freiberg's disease. This approach offers a valuable addition to the treatment armamentarium, providing patients with a minimally invasive yet effective solution for their condition.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 2","pages":"Pages 53-57"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two cases of treatment of the seymour fracture complicated by pyogenic arthritis with antibiotic-impregnated calcium phosphate paste granules 浸渍磷酸钙糊粒治疗西摩骨折合并化脓性关节炎2例

JOS Case Reports Pub Date : 2025-06-01 Epub Date: 2025-01-04 DOI: 10.1016/j.joscr.2024.12.001

Koki Hosozawa , Ryoichi Shibuya , Satoshi Miyamura , Toru Iwahashi , Takeshi Fuji

{"title":"Two cases of treatment of the seymour fracture complicated by pyogenic arthritis with antibiotic-impregnated calcium phosphate paste granules","authors":"Koki Hosozawa , Ryoichi Shibuya , Satoshi Miyamura , Toru Iwahashi , Takeshi Fuji","doi":"10.1016/j.joscr.2024.12.001","DOIUrl":"10.1016/j.joscr.2024.12.001","url":null,"abstract":"<div><h3>Background</h3><div>Seymour fractures are physeal fractures of the distal phalanx in children. These fractures are difficult to treat because they frequently lead to infections. We report two cases of Seymour fractures complicated by pyogenic arthritis, treated with vancomycin-impregnated paste granules of calcium phosphate cement, that showed good outcomes.</div></div><div><h3>Case presentation</h3><div>Two teenagers injured their fingers during rugby. They visited the outpatient clinic several days after the injury, presenting with purulent material discharge from the nail bed detachment. X-ray and MRI showed physeal fractures with associated inflammation, resulting in the diagnosis of Seymour fractures complicated by pyogenic arthritis and osteomyelitis. The wounds were irrigated and debrided, and the bone defect was filled with vancomycin-impregnated paste granules of calcium phosphate cement. While the growth plates closed prematurely, no recurrence of infection occurred.</div></div><div><h3>Conclusion</h3><div>In Seymour fractures complicated by pyogenic arthritis, vancomycin-impregnated paste granules of calcium phosphate cement are effective in controlling infection.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 2","pages":"Pages 63-66"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipoma arborescens and synovial chondromatosis with subacromial bursal effusion 树状脂肪瘤和伴肩峰下囊积液的滑膜软骨瘤病

JOS Case Reports Pub Date : 2025-06-01 Epub Date: 2024-09-10 DOI: 10.1016/j.joscr.2024.08.002

Shu Yoshizawa, Hiroyasu Ikegami, Takanori Shintaku, Misato Sakamoto, Takahiro Maeda, Tomoyasu Honma, Yoshiro Musha, Hideaki Ishii

引用次数: 0

Single-cell RNA profiling of the primary tumor and metastatic lymph node lesions in a patient with clear cell sarcoma of soft tissue: A case report 对一名软组织透明细胞肉瘤患者的原发肿瘤和转移淋巴结病灶进行单细胞 RNA 分析：病例报告

JOS Case Reports Pub Date : 2025-03-01 Epub Date: 2024-07-24 DOI: 10.1016/j.joscr.2024.07.003

Yusuke Tsuda , Hiroyuki Okada , Kotoe Katayama , Toshihide Hirai , Jyunya Miyahara , Liuzhe Zhang , Yasunori Omata , Kasumi Abe , Yutaka Suzuki , Sakae Tanaka , Hiroshi Kobayashi

{"title":"Single-cell RNA profiling of the primary tumor and metastatic lymph node lesions in a patient with clear cell sarcoma of soft tissue: A case report","authors":"Yusuke Tsuda , Hiroyuki Okada , Kotoe Katayama , Toshihide Hirai , Jyunya Miyahara , Liuzhe Zhang , Yasunori Omata , Kasumi Abe , Yutaka Suzuki , Sakae Tanaka , Hiroshi Kobayashi","doi":"10.1016/j.joscr.2024.07.003","DOIUrl":"10.1016/j.joscr.2024.07.003","url":null,"abstract":"<div><h3>Background</h3><div>There was no report which evaluated the cellular constitution and cell–cell interactions in clear cell sarcoma of soft tissue.</div></div><div><h3>Case presentation</h3><div>A 47-year-old woman underwent surgical excision of clear cell sarcoma in right knee and inguinal lymph node metastasis after neo-adjuvant chemotherapy. However, she died due to liver and para-aortic lymph node metastasis. Single-cell RNA sequencing of the primary tumor and metastatic lymph node samples revealed the accumulation of <em>CTLA4</em><sup><em>+</em></sup><em>/CD4</em><sup><em>+</em></sup> regulatory and <em>LAG3</em><sup>+</sup>/<em>CD8</em><sup>+</sup> exhausted T cells particularly in the metastatic lymph node. NicheNet analysis indicated that these T cell states were induced by the interplay of T cells with tumor cells, macrophages, B cells, fibroblasts, and endothelial cell.</div></div><div><h3>Conclusions</h3><div>The cellular constitution of immune and stromal cell types and their properties suggested the presence of T cell immunosuppression in the clear cell sarcoma microenvironment.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 1","pages":"Pages 24-33"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141850463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Atlantoaxial subluxation correction using the magerl and brooks techniques in patients with metatropic dysplasia: A report on a case involving siblings 异萎缩性发育不良患者应用magerl和brooks技术矫正寰枢半脱位：一个涉及兄弟姐妹的病例报告

JOS Case Reports Pub Date : 2025-03-01 Epub Date: 2024-06-25 DOI: 10.1016/j.joscr.2024.06.004

Toshiyuki Ogata , Satoshi Suzuki , Yohei Takahashi , Satoshi Nori , Osahiko Tsuji , Narihito Nagoshi , Mitsuru Yagi , Kota Watanabe , Masaya Nakamura , Morio Matsumoto

{"title":"Atlantoaxial subluxation correction using the magerl and brooks techniques in patients with metatropic dysplasia: A report on a case involving siblings","authors":"Toshiyuki Ogata , Satoshi Suzuki , Yohei Takahashi , Satoshi Nori , Osahiko Tsuji , Narihito Nagoshi , Mitsuru Yagi , Kota Watanabe , Masaya Nakamura , Morio Matsumoto","doi":"10.1016/j.joscr.2024.06.004","DOIUrl":"10.1016/j.joscr.2024.06.004","url":null,"abstract":"<div><h3>Background</h3><div>Metatropic dysplasia (MD) is a form of skeletal dysplasia characterized by short limbs, stature, and kyphoscoliosis. Cervical instability and odontoid hypoplasia are reported as relatively common symptoms; however, surgical treatment is rarely reported. Although upper cervical spine surgery in pediatric patients is challenging because of their peculiar tissue biology, few studies have demonstrated the use of Magerl screws.</div></div><div><h3>Case presentation</h3><div>We describe two sibling cases that were successfully treated for atlantoaxial subluxation of MD using Magerl and Brooks techniques in which bone union of the vertebrae was achieved. C1–C2 fusion surgery for treating atlantoaxial subluxation in pediatric patients with MD is rare.</div></div><div><h3>Conclusions</h3><div>The present report is doubly remarkable by the unprecedented use of the Magerl and Brooks techniques and because the patients were siblings. The use of the Magerl and Brooks techniques achieved good efficacy, but careful consideration is required in the insertion of transarticular screws.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 1","pages":"Pages 5-9"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143487689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tibial fracture arising from bone amyloidosis: A case study 骨淀粉样变性引起的胫骨骨折：病例研究

JOS Case Reports Pub Date : 2025-03-01 Epub Date: 2024-07-25 DOI: 10.1016/j.joscr.2024.07.002

Akane Yamamoto , Tomoaki Fukui , Takahiro Niikura , Kenichi Sawauchi , Masato Komatsu , Ryosuke Kuroda , Keisuke Oe

引用次数: 0

Anterior intraosseous arthroscopic treatment of talar chondroblastoma: A case report 前路骨内关节镜治疗距骨成软骨细胞瘤1例

JOS Case Reports Pub Date : 2025-03-01 Epub Date: 2024-06-29 DOI: 10.1016/j.joscr.2024.06.003

Myongsu Ha , Kenjiro Wakabayashi , Hikotaro Umemura , Yukie Yakita , Masaki Hasegawa , Hiroki Yonezu , Yoshiaki Tsuboi , Hideki Murakami

引用次数: 0

Pediatric epithelioid haemangioma with intra- and exra-articular involvement around the hip joint: A case report 小儿上皮样血管瘤累及髋关节周围的关节内和关节外：病例报告

JOS Case Reports Pub Date : 2025-03-01 Epub Date: 2024-07-19 DOI: 10.1016/j.joscr.2024.06.005

Masayuki Morishita , Makiko Yoshida , Shinichi Satsuma , Hitomi Kitamura , Azusa Yoneda , Izumi Komoto , Maki Kinugasa , Ryosuke Sakata , Daisuke Kobayashi

{"title":"Pediatric epithelioid haemangioma with intra- and exra-articular involvement around the hip joint: A case report","authors":"Masayuki Morishita , Makiko Yoshida , Shinichi Satsuma , Hitomi Kitamura , Azusa Yoneda , Izumi Komoto , Maki Kinugasa , Ryosuke Sakata , Daisuke Kobayashi","doi":"10.1016/j.joscr.2024.06.005","DOIUrl":"10.1016/j.joscr.2024.06.005","url":null,"abstract":"<div><h3>Background</h3><div>Intra-articular tumors of the hip are rare in pediatric patients, often leading to delayed diagnosis and mismanagement. Improved imaging techniques have enhanced detection. However, differentiating benign from malignant tumors remains challenging. Additionally, managing these tumors in children require considering the impact on growth and long-term functions.</div></div><div><h3>Case presentation</h3><div>A 6-year-old boy presented with right lower extremity pain that worsened after a fall. Radiographs revealed cortical irregularities in the greater trochanter and the medial calcar of the femur. Magnetic resonance imaging showed irregular masses, and an incisional biopsy confirmed epithelioid haemangioma (EH). Post-biopsy, the patient's hip pain improved despite residual limping, avoiding further surgery.</div></div><div><h3>Conclusion</h3><div>This pediatric EH case emphasizes the importance of accurate diagnosis and tailored treatment in rare cases. Although partial resection improved symptoms, continued monitoring is vital due to the unpredictability of pediatric EH. Genetic analysis can potentially enhance diagnostic accuracy in future cases.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 1","pages":"Pages 14-18"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141851159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Treatment for congenital unilateral hip dislocation with ipsilateral below-knee hemimelia: A case report 先天性单侧髋关节脱位伴同侧膝下半畸形的治疗方法：病例报告

JOS Case Reports Pub Date : 2025-03-01 Epub Date: 2024-07-14 DOI: 10.1016/j.joscr.2024.07.001

Hiroki Fujita , Toshiya Nosaka , Atsushi Teramoto

引用次数: 0