JOS Case Reports最新文献_第2页

Long-term efficacy of eribulin in patients with advanced myxoid liposarcoma resistant to trabectedin: A case report 伊瑞布林治疗耐药晚期黏液样脂肪肉瘤的长期疗效：1例报告

JOS Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.joscr.2024.06.002

Kazuma Arai , Koichi Okajima , Yuki Ishibashi , Yusuke Tsuda , Shinji Kohsaka , Yoichi Yasunaga , Kohichi Takada , Makoto Emori , Tetsuo Ushiku , Katsutoshi Oda , Kiyoshi Miyagawa , Hiroyuki Aburatani , Hiroyuki Mano , Sakae Tanaka , Hiroshi Kobayashi

{"title":"Long-term efficacy of eribulin in patients with advanced myxoid liposarcoma resistant to trabectedin: A case report","authors":"Kazuma Arai , Koichi Okajima , Yuki Ishibashi , Yusuke Tsuda , Shinji Kohsaka , Yoichi Yasunaga , Kohichi Takada , Makoto Emori , Tetsuo Ushiku , Katsutoshi Oda , Kiyoshi Miyagawa , Hiroyuki Aburatani , Hiroyuki Mano , Sakae Tanaka , Hiroshi Kobayashi","doi":"10.1016/j.joscr.2024.06.002","DOIUrl":"10.1016/j.joscr.2024.06.002","url":null,"abstract":"<div><h3>Background</h3><div>Myxoid liposarcoma is sensitive to trabectedin, but less sensitive to eribulin.</div></div><div><h3>Case presentation</h3><div>A 47-year-old man presented to our hospital with a right leg mass, biopsy of which revealed myxoid liposarcoma. Surgical resection was performed and perioperative chemotherapy was administered. Eighteen years postoperatively, the patient developed pericardial metastasis causing cardiac tamponade, and radiotherapy was administered. One year later, mesenteric metastasis occurred and the tumor was resected. One year later to this, multiple metastases, including recurrent mesenteric metastases, occurred. As the metastases progressed after two cycles of trabectedin treatment, eribulin was initiated, resulting in a partial response. Eribulin was continued for 18 months without severe adverse events. Genetic testing of the resected mesenteric tumor revealed a <em>PIK3CA</em> (p.H1047R) mutation, and immunohistochemistry for phosphorylated AKT was negative.</div></div><div><h3>Conclusions</h3><div>This report of long-term successful treatment of trabectedin-resistant myxoid liposarcoma with eribulin suggests sensitivity mechanism to eribulin in myxoid liposarcoma with <em>PIK3CA</em> mutation.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"3 4","pages":"Pages 209-213"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143152399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chipping corrective osteotomy and autologous bone graft for malrotation with nonunion of a subtrochanteric femoral fracture: A case report 削骨矫正截骨术和自体骨移植治疗股骨转子下骨折旋转不良伴不愈合：病例报告

JOS Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.joscr.2024.06.001

Masaki Takahashi, Juji Ito, Takeshi Sameshima, Michiaki Takagi, Yuya Takakubo

{"title":"Chipping corrective osteotomy and autologous bone graft for malrotation with nonunion of a subtrochanteric femoral fracture: A case report","authors":"Masaki Takahashi, Juji Ito, Takeshi Sameshima, Michiaki Takagi, Yuya Takakubo","doi":"10.1016/j.joscr.2024.06.001","DOIUrl":"10.1016/j.joscr.2024.06.001","url":null,"abstract":"<div><h3>Background</h3><div>With subtrochanteric femoral fractures, it is often difficult to achieve appropriate positioning after reduction, and these fractures have a high risk of nonunion and malrotation. We report a case in which chipping corrective (CCO)was performed for nonunion and malrotation after subtrochanteric femoral fracture repair.</div></div><div><h3>Case presentation</h3><div>A 61-year-old man sustained a left femoral subtrochanteric fracture. Bone union was not achieved 2 years after the initial surgery. Additional surgery with CCO was performed 2 years and 9 months after the initial surgery. One year after CCO, bone union had been achieved circumferentially, and the difference in anteversion of the femoral neck from the opposite side had decreased from 49.3° preoperatively to 2.4° postoperatively.</div></div><div><h3>Conclusions</h3><div>CCO is useful for nonunion of subtrochanteric femoral fractures with malrotation. To our knowledge, there are no previous reports of CCO for postoperative nonunion of subtrochanteric femoral fractures.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"3 4","pages":"Pages 205-208"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Retroperitoneal continuous local antibiotic perfusion for surgical site infection after lumbar lateral interbody fusion: A case report 腹膜后持续局部抗生素灌注治疗腰椎外侧椎体间融合术后手术部位感染1例

JOS Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.joscr.2024.05.002

Yawara Eguchi , Noritaka Suzuki , Sumihisa Orita , Kazuhide Inage , Miyako Narita , Yasuhiro Shiga , Masahiro Inoue , Soichiro Tokeshi , Kohei Okuyama , Shuhei Ohyama , Yasuchika Aoki , Junichi Nakamura , Shigeo Hagiwara , Yuya Kawarai , Tsutomu Akazawa , Masao Koda , Hiroshi Takahashi , Seiji Ohtori

{"title":"Retroperitoneal continuous local antibiotic perfusion for surgical site infection after lumbar lateral interbody fusion: A case report","authors":"Yawara Eguchi , Noritaka Suzuki , Sumihisa Orita , Kazuhide Inage , Miyako Narita , Yasuhiro Shiga , Masahiro Inoue , Soichiro Tokeshi , Kohei Okuyama , Shuhei Ohyama , Yasuchika Aoki , Junichi Nakamura , Shigeo Hagiwara , Yuya Kawarai , Tsutomu Akazawa , Masao Koda , Hiroshi Takahashi , Seiji Ohtori","doi":"10.1016/j.joscr.2024.05.002","DOIUrl":"10.1016/j.joscr.2024.05.002","url":null,"abstract":"<div><h3>Background</h3><div>Surgical site infection (SSI) after instrumented spinal surgery (ISS) is one of the most serious surgical complications. Treatment is often difficult, with many cases requiring removal of the implant.</div></div><div><h3>Case presentation</h3><div>An 80-year-old man developed refractory MRSA SSI after L4-5 Oblique Lateral Interbody Fusion surgery for a multiply operated back. Local debridement and retroperitoneal continuous local antibiotic perfusion (CLAP) were performed to preserve the implant. One month later, a second CLAP was performed for T6-7 suppurative spondylitis that had disseminated remotely to the thoracic spine. Following this, the lumbar spine and thoracic spine abscess, inflammatory response, and low back pain were reduced dramatically, and the implant was saved.</div></div><div><h3>Conclusion</h3><div>Even in the case of SSI after refractory anterior ISS, CLAP is a procedure worth trying first, as it is easy to install and manage, and will possibly control infection to preserve the implant.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"3 4","pages":"Pages 190-195"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143152741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pediatric gymnast with type 1 manubriosternal joint dislocation recovered by remodeling with conservative treatment: A case report 患 1 型胸肋关节脱位的小儿体操运动员通过重塑和保守治疗康复：病例报告

JOS Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.joscr.2024.05.001

Hideki Hiraiwa , Tadahiro Sakai , Shinya Ishizuka , Hiroki Oba , Takafumi Mizuno , Takashi Tsukahara , Shiro Imagama

引用次数: 0

Guided growth for angular correction in valgus knee deformity following subtotal meniscectomy of the discoid lateral meniscus in a juvenile knee: A case report 青少年膝关节盘状外侧半月板次全切除术后膝外翻畸形的角度矫正引导生长：病例报告

JOS Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.joscr.2024.04.002

Keisuke Maeda, Tomoharu Mochizuki, Reiko Murakami, Osamu Tanifuji, Hiroyuki Kawashima

{"title":"Guided growth for angular correction in valgus knee deformity following subtotal meniscectomy of the discoid lateral meniscus in a juvenile knee: A case report","authors":"Keisuke Maeda, Tomoharu Mochizuki, Reiko Murakami, Osamu Tanifuji, Hiroyuki Kawashima","doi":"10.1016/j.joscr.2024.04.002","DOIUrl":"10.1016/j.joscr.2024.04.002","url":null,"abstract":"<div><h3>Introduction</h3><div>Few studies have reported the development of severe knee deformities after total or subtotal meniscectomy for juvenile discoid lateral menisci (DLM). We report a juvenile case of valgus knee deformity and severe chondral lesions after subtotal meniscectomy.</div></div><div><h3>Case presentation</h3><div>A 6-year-old girl with DLM underwent subtotal meniscectomy of the anterior and middle menisci. At the age of 11 years, imaging showed severe valgus knee deformity with morphological deformities and severe chondral lesions. An Eight-Plate hemiepiphysiodesis-guided growth method was used to gradually correct the lower leg alignment. Currently, the desired alignment with improvement of the bony deformity and cartilage has been achieved.</div></div><div><h3>Conclusions</h3><div>In a juvenile knee with valgus bony deformity and severe chondral lesions, the gradual correction of valgus deformity through temporary hemiepiphysiodesis resulted in an improvement in bone deformity and cartilage defect.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"3 4","pages":"Pages 181-186"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141033534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An alternative goal of conservative treatment in elite pediatric athletes with lumbar spondylolysis: A case report and literature review 腰椎溶解症儿科精英运动员保守治疗的另一个目标：病例报告和文献综述

JOS Case Reports Pub Date : 2024-12-01 DOI: 10.1016/j.joscr.2024.05.004

Shutaro Fujimoto , Shunsuke Tamaki , Kosuke Sugiura , Makoto Takeuchi , Masatoshi Morimoto , Fumitake Tezuka , Kazuta Yamashita , Koichi Sairyo

{"title":"An alternative goal of conservative treatment in elite pediatric athletes with lumbar spondylolysis: A case report and literature review","authors":"Shutaro Fujimoto , Shunsuke Tamaki , Kosuke Sugiura , Makoto Takeuchi , Masatoshi Morimoto , Fumitake Tezuka , Kazuta Yamashita , Koichi Sairyo","doi":"10.1016/j.joscr.2024.05.004","DOIUrl":"10.1016/j.joscr.2024.05.004","url":null,"abstract":"<div><h3>Background</h3><div>The main conservative treatment strategies for lumbar spondylolysis are bone healing and pain management. Bone healing requires cessation of sports, which may be difficult for pediatric athletes.</div></div><div><h3>Case presentation</h3><div>A 15-year-old female athlete had bilateral L2 spondylolysis (right: very-early stage; left: progressive). Radiographs suggested vertebral maturity. Although bone healing could be expected on both sides, we aimed for continuation of play because she was a candidate for a national-level team attending an international competition. We implemented strenuous athletic rehabilitation based on joint-by-joint theory to reduce lumbar spine loading. A pars fracture led to pseudoarthrosis, but she continued playing and participated in the competition without problem.</div></div><div><h3>Conclusions</h3><div>In pediatric patients with spondylolysis and low risk of slippage, treatment aimed at continuation of play and pain management rather than bone healing may be considered, particularly in elite athletes. Strenuous athletic rehabilitation, including thoracic spine mobilization, is essential in such cases.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"3 4","pages":"Pages 201-204"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141411807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Osteochondral fragment fixation for Freiberg's disease: A report of three cases 骨软骨碎片固定治疗Freiberg病3例报告

JOS Case Reports Pub Date : 2024-11-25 DOI: 10.1016/j.joscr.2024.11.001

Ryo Fukagawa , Ichiro Yoshimura , Tomonobu Hagio , Tetsuro Ishimatsu , Yuki Sugino , Seiya Tomonaga , Yoshimasa Taniguchi , Takuaki Yamamoto

{"title":"Osteochondral fragment fixation for Freiberg's disease: A report of three cases","authors":"Ryo Fukagawa , Ichiro Yoshimura , Tomonobu Hagio , Tetsuro Ishimatsu , Yuki Sugino , Seiya Tomonaga , Yoshimasa Taniguchi , Takuaki Yamamoto","doi":"10.1016/j.joscr.2024.11.001","DOIUrl":"10.1016/j.joscr.2024.11.001","url":null,"abstract":"<div><h3>Background</h3><div>Freiberg's disease is characterized by osteonecrosis of the metatarsal head and is most common in teenage girls who play sports. Various treatment options are selected depending on the disease progression. When conservative measures fail, dorsiflexion osteotomy or osteochondral grafting are often performed. However, each approach has its drawbacks. Herein, we present three cases in which Freiberg's disease was effectively managed with osteochondral fragment fixation, circumventing the limitations associated with traditional treatment methods.</div></div><div><h3>Case presentation</h3><div>We describe three teenagers with Frieberg's disease who failed to respond to conservative treatment. The osteochondral fragment was stabilized using absorbable pins, thereby preserving the articular cartilage and maintaining the joint congruity. All three patients achieved substantial pain relief and functional improvement postoperatively.</div></div><div><h3>Conclusion</h3><div>Osteochondral fragment fixation is a promising alternative for the management of Freiberg's disease. This approach offers a valuable addition to the treatment armamentarium, providing patients with a minimally invasive yet effective solution for their condition.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 2","pages":"Pages 53-57"},"PeriodicalIF":0.0,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spinal meningeal melanocytoma with extensive dura mater pigmentation: Review of meningeal melanocytic tumors with GNAQ mutations 伴有广泛硬脑膜色素沉着的脊膜黑素细胞瘤：伴有GNAQ突变的脊膜黑素细胞瘤的研究综述

JOS Case Reports Pub Date : 2024-11-06 DOI: 10.1016/j.joscr.2024.10.001

Kazumichi Yagura , Shu Takahashi , Kazuyuki Segami , Yusuke Oshita , Genshu Tate , Koji Kanzaki , Tomoaki Toyone , Yoshifumi Kudo

{"title":"Spinal meningeal melanocytoma with extensive dura mater pigmentation: Review of meningeal melanocytic tumors with GNAQ mutations","authors":"Kazumichi Yagura , Shu Takahashi , Kazuyuki Segami , Yusuke Oshita , Genshu Tate , Koji Kanzaki , Tomoaki Toyone , Yoshifumi Kudo","doi":"10.1016/j.joscr.2024.10.001","DOIUrl":"10.1016/j.joscr.2024.10.001","url":null,"abstract":"<div><h3>Background</h3><div>Meningeal melanocytoma is an extremely rare benign tumor. Although gross total resection of the tumor is the most effective therapy, consensus regarding the management of adjacent pigmented dura mater is lacking. Here, we present a case of meningeal melanocytoma with extensive dura mater pigmentation and discuss the importance of <em>GNAQ</em> mutations in making the diagnosis.</div></div><div><h3>Case presentation</h3><div>A 37-year-old woman presented with bilateral leg weakness. Magnetic resonance imaging revealed a thoracic intradural extramedullary mass. A solid blackish tumor wrapped in dark-pigmented dura mater was excised. No neoplasms were detected in the dura mater or on cerebrospinal fluid analysis. Genetic analysis revealed a <em>GNAQ</em> mutation. The mass was diagnosed as a meningeal melanocytoma. No recurrence was observed during 2 years of follow-up.</div></div><div><h3>Conclusions</h3><div>Histopathological analysis of the dura mater and cytological analysis of the cerebrospinal fluid is useful for deciding whether to administer adjuvant therapy.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 2","pages":"Pages 48-52"},"PeriodicalIF":0.0,"publicationDate":"2024-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lipoma arborescens and synovial chondromatosis with subacromial bursal effusion 树状脂肪瘤和伴肩峰下囊积液的滑膜软骨瘤病

JOS Case Reports Pub Date : 2024-09-10 DOI: 10.1016/j.joscr.2024.08.002

Shu Yoshizawa, Hiroyasu Ikegami, Takanori Shintaku, Misato Sakamoto, Takahiro Maeda, Tomoyasu Honma, Yoshiro Musha, Hideaki Ishii

引用次数: 0

Nonunion of fourth metatarsal base stress fracture in athletes treated with locking plate fixation and iliac bone grafting: A three-case report 锁定钢板固定联合髂骨移植治疗运动员第四跖骨基底应力性骨折不愈合3例报告

JOS Case Reports Pub Date : 2024-09-02 DOI: 10.1016/j.joscr.2024.08.003

Shota Morimoto, Futoshi Morio, Toshiya Tachibana, Tomoya Iseki

{"title":"Nonunion of fourth metatarsal base stress fracture in athletes treated with locking plate fixation and iliac bone grafting: A three-case report","authors":"Shota Morimoto, Futoshi Morio, Toshiya Tachibana, Tomoya Iseki","doi":"10.1016/j.joscr.2024.08.003","DOIUrl":"10.1016/j.joscr.2024.08.003","url":null,"abstract":"<div><h3>Background</h3><div>Fourth metatarsal base stress fractures have been reported to cause complications, such as a substantial rate of delayed union and nonunion when treated nonoperatively. This report details three cases of nonunion of basal stress fractures of the fourth metatarsal in athletes who were successfully treated with a combination of locking plate fixation and iliac bone grafting.</div></div><div><h3>Case presentation</h3><div>Three male athletes presented with nonunion of fourth metatarsal base stress fracture and underwent surgical treatment. In all cases, the nonunion site was decorticated, and iliac cancellous bone was grafted to the nonunion site. The bone fragments were reduced in a correct bone alignment and fixed using a locking plate. All the athletes obtained bone union and returned to the original sport at 12 weeks postoperatively.</div></div><div><h3>Conclusions</h3><div>Surgical treatment combining locking plate fixation and iliac bone grafting for nonunion of a fourth metatarsal base stress fracture in athletes produced satisfactory results.</div></div>","PeriodicalId":100743,"journal":{"name":"JOS Case Reports","volume":"4 2","pages":"Pages 44-47"},"PeriodicalIF":0.0,"publicationDate":"2024-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144169677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0