Hybrid Advances最新文献

{"title":"Development of targeted nanocapsules using pomegranate peel extract with enhanced bioavailability and anti-inflammatory activity for ulcerative colitis: In vitro studies","authors":"P. Monika ,&nbsp;M.N. Chandraprabha ,&nbsp;R. Hari Krishna ,&nbsp;Vittal Maanya ,&nbsp;C. Likhitha ,&nbsp;N. Pooja","doi":"10.1016/j.hybadv.2024.100334","DOIUrl":"10.1016/j.hybadv.2024.100334","url":null,"abstract":"<div><div>The study aimed to establish an accurate drug delivery system with a tailored mechanism for the efficient management of Ulcerative Colitis (UC). Using the solvent evaporation technique, nanoencapsulation of pomegranate peel extract (PPE) in biodegradable enteric polymer methacrylic acid-ethyl acrylate copolymer (Eudragit L-100) was prepared. <em>In vitro</em> drug release investigations indicated a greater percentage of drug released at 6.8 pH in contrast to 7.4 pH (96.98 ± 0.80 % vs. 93.97 ± 0.711 %), indicating its applicability in the region of the human intestine. The mechanism of drug release from the nanoformulations (NFR) exhibited a process controlled by Fickian diffusion. The results suggest efficient encapsulation of PPE within Eudragit L100 and may be used for targeted drug release in the intestinal region. Anti-inflammatory studies on the HIEC-6 cell line showed that tumour necrosis factor-α (TNF-α) expression was significantly (p &lt; 0.001) decreased in all NFRs. Additionally, NFRs exhibited antioxidant activity and enhanced <em>in vitro</em> bioavailability (in intestinal pH compared to gastric pH).</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"7 ","pages":"Article 100334"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142757524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case study on the potential benefits of using expanded polystyrene geofoam to mitigate seismic impact on structures","authors":"Hasan Muhommed Ashiq ,&nbsp;Shadman Rahman Sabab ,&nbsp;Mozaher Ul Kabir ,&nbsp;Chowdhury Zubayer Bin Zahid ,&nbsp;Md Rahat Hassan","doi":"10.1016/j.hybadv.2024.100336","DOIUrl":"10.1016/j.hybadv.2024.100336","url":null,"abstract":"<div><div>Expanded Polystyrene (EPS) geofoam has been utilized in construction in a wide range of countries for years. EPS serves as a compressible buffer between the soil and the structure itself. It absorbs a significant percentage of the static and dynamic stresses induced by earthquake-loaded soil. Because Bangladesh is prone to earthquakes and Chittagong is a high seismic risk zone, the use of EPS in buildings could be a great solution for decreasing seismic damage. In this study, the impact of implementing EPS as a compressible buffer around the substructure on Chittagong soil against seismic load was investigated using Plaxis3D software to generate a finite element model. The study compared two scenarios, one with and one without EPS 15 put around the structure's basement, to examine the impact of an earthquake on a five-story building. The wave oscillation graphs that were generated were used to build the energy (J) vs time (s) graphs to compare the findings. The results reveal that applying EPS 15 allows for better energy dissipation over time than without it, indicating that EPS has the potential to decrease seismic damage to a structure.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"7 ","pages":"Article 100336"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142747684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced microstructural properties and biocompatibility of Zinc oxide nanoparticles by biogenic synthesis protocol for antibacterial applications","authors":"Henrietta Onyinye Uzoeto ,&nbsp;Anthonia Nkiru ,&nbsp;Samson O. Aisida ,&nbsp;Fabian I. Ezema","doi":"10.1016/j.hybadv.2024.100332","DOIUrl":"10.1016/j.hybadv.2024.100332","url":null,"abstract":"<div><div>Green synthesis of functional oxides such as zinc oxide has been trending recently owing to their biomedical applications. This work involves a biosynthesis protocol using GONGROLEMA LATIFOLIUM (GL) aqueous extract as a stabilizing agent for the first time. The physicochemical properties of the obtained samples were determined using different techniques. X-ray diffraction (XRD) was employed to estimate the structural properties, while, the morphology structure was obtained using scanning electron microscopy (SEM). The absorbance was obtained using UV–visible spectroscopy while the functional group was obtained using the Fourier transform infrared (FT-IR) Spectroscopy. The GL in the sample enhanced their biocompatibility, making it more suitable for biomedical applications. Some selected drug-resistant pathogens were used to evaluate the biomedical activities of the samples. <em>Staphylococcus aureus</em> showed higher activities compared with <em>Escherichia coli, Enterobacter coliform and</em> Ciprofloxacin. Hence, the formulated material is promising as a potential antimicrobial agent.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"7 ","pages":"Article 100332"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thermal conductivity & thermal diffusivity of hybrid materials: State of the art and perspectives","authors":"Claudio Tosto,&nbsp;Ljubiša Balanović","doi":"10.1016/j.hybadv.2024.100323","DOIUrl":"10.1016/j.hybadv.2024.100323","url":null,"abstract":"","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"7 ","pages":"Article 100323"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143178622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An effect of waste discharge concentration and electromagnetic field on chemically reactive Bingham fluid flow with the analysis entropy generation and mass transfer","authors":"S.M. Sachhin ,&nbsp;U.S. Mahabaleshwar ,&nbsp;N. Swaminathan ,&nbsp;David Laroze ,&nbsp;Liliana Pedraja-Rejas","doi":"10.1016/j.hybadv.2024.100344","DOIUrl":"10.1016/j.hybadv.2024.100344","url":null,"abstract":"<div><div>In modern days, proper waste fluid disposal is important in different industries and ecological systems. The present article aims to prevent and resolve pollution in the fluids supply. Implementing advanced treatment processes, such as filtration, sedimentation, and chemical treatment, can help in reducing the concentration of pollutants in waste discharge, and we can use Bingham fluids in industries to manage the flow of waste materials, ensuring that pollutants are contained and treated effectively before discharge. The article investigates the impact of pollutant discharge concentration on the movement of non-Newtonian Bingham hybrid nanofluids across permeable expanding surfaces, taking into account the influence of electromagnetic field, Joule heating, and chemical reaction effects. There is a lack of study on electromagnetic and Joule heating effects on chemically reactive hybrid nanofluids with energy and mass transfer, authors utilized the research gap. Heat source/sink effects were added to the temperature equation, to understand the irreversibility of processes functionality authors studied the entropy generation analysis, partial differential equations are calculated into ordinary differential solutions by similarity variables after that, they are calculated by using the shooting method. Outcomes reveal that increasing the magnetic field decreases the velocity, increasing the external source difference factor and external pollutant term increases the concentration of the fluid movement, upsurging the thermal radiation parameter upsurges the temperature and entropy generation, increasing the porosity parameter decreases the velocity of the fluid flow, increasing the Bingham parameter decreases the velocity of the fluid flow which are used in processes involving slurries, pastes, and other materials that require controlled flow under specific stress conditions.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"8 ","pages":"Article 100344"},"PeriodicalIF":0.0,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and characterization of sterculia gum-zwitterionic sulfobetaine-PVP based network hydrogels for biomedical application","authors":"Ankita Kumari,&nbsp;Diwanshi Sharma,&nbsp;Vikrant Sharma,&nbsp;Baljit Singh","doi":"10.1016/j.hybadv.2024.100341","DOIUrl":"10.1016/j.hybadv.2024.100341","url":null,"abstract":"<div><div>Recently, various attempts are being made to design functional material from bioactive polysaccharide to explore their potential for clinical applications. Herein, zwitterionic sulfobetaine and polyvinylpyrrolidone (PVP) functional material was incorporated into bioactive sterculia gum (SG) for developing material in form of network structure hydrogel for use in biomedical applications. Copolymeric films were characterized by FESEM, EDS, AFM, FTIR, ¹³C NMR, XRD, DSC, mechanical properties &amp; biomedical assay. Antibiotic drug was impregnated into hydrogel to enhance their healing potential for wound. Various biomedical results assessed from biomedical assays revealed their biocompatible &amp; antioxidant nature. Hydrogel material revealed 34.80 ± 0.15 % scavenging ability of DPPH radicals. These dressing demonstrated bioadhesive characteristics and revealed their permeable nature to H₂O &amp; O₂. Hydrogel dressing demonstrated 0.63 ± 0.02 N mm⁻² tensile strength for dressing; 27.58 ± 2.84 N burst strength of materials along with elastic &amp; resilience features were also analyzed. Dressing material revealed antimicrobial property against <em>P. aeruginosa, E.coli.</em> &amp; <em>S. aureus.</em> Diffusion mechanism of cefuroxime was non-Fickian &amp; followed Higuchi kinetic model. In ¹³C NMR confirmed inclusion of PMEDSAH-PVP onto SG by revealing of peaks around 62.11 ppm on an account of CH₂–<u>C</u>H–SO₃^- of PMEDSAH, and peak at 43.34 ppm is due to carbon of pyrrolidone ring of PVP indicating integration of PVP into copolymeric film. Where in FTIR presence of bands at 1290 cm⁻¹ attributed to <em>C</em>–N vibration of PVP, 1144 cm⁻¹ due to SO₃⁻ asymmetric stretching along with band 1651 cm⁻¹ by virtue C<img>O stretching of amide of PVP. Overall these properties revealed that drug encapsulated materials could be utilize for biomedical applications including drug delivery.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"8 ","pages":"Article 100341"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Solid-State lithium-ion battery electrolytes: Revolutionizing energy density and safety","authors":"P.U. Nzereogu ,&nbsp;A. Oyesanya ,&nbsp;S.N. Ogba ,&nbsp;S.O. Ayanwunmi ,&nbsp;M.S. Sobajo ,&nbsp;V.C. Chimsunum ,&nbsp;V.O. Ayanwunmi ,&nbsp;M.O. Amoo ,&nbsp;O.T. Adefemi ,&nbsp;C.C. Chukwudi","doi":"10.1016/j.hybadv.2024.100339","DOIUrl":"10.1016/j.hybadv.2024.100339","url":null,"abstract":"<div><div>Solid-state lithium-ion batteries (SSLIBs) are poised to revolutionize energy storage, offering substantial improvements in energy density, safety, and environmental sustainability. This review provides an in-depth examination of solid-state electrolytes (SSEs), a critical component enabling SSLIBs to surpass the limitations of traditional lithium-ion batteries (LIBs) with liquid electrolytes. Conventional LIBs face significant challenges such as thermal instability, flammability, leakage, limited electrochemical windows, and environmental concerns. SSLIBs, however, eliminate these risks by utilizing solid electrolytes, which exhibit higher ionic conductivities, increased electrochemical stability, and reduced safety hazards. This review explores a variety of solid electrolytes, including oxide, sulfide, perovskite, anti-perovskite, NASICON, and LISICON-based materials, each with unique structural and electrochemical properties that enhance lithium-ion mobility and battery performance. Additionally, advancements in interfacial engineering, cathode and anode material optimization, and manufacturing techniques are discussed. The potential of SSLIBs in transforming applications across industries—from electric vehicles to large-scale energy storage systems—is underscored, highlighting the path toward more efficient, safer, and sustainable battery technologies.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"8 ","pages":"Article 100339"},"PeriodicalIF":0.0,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Research progress on green adsorption process for water pollution control applications","authors":"Opeyemi A. Oyewo ,&nbsp;Anthony M. Muliwa ,&nbsp;Seshibe S. Makgato ,&nbsp;Damian C. Onwudiwe","doi":"10.1016/j.hybadv.2024.100338","DOIUrl":"10.1016/j.hybadv.2024.100338","url":null,"abstract":"<div><div>Anthropogenic activities, such as domestic, agricultural, and industrial activities, are responsible for the increased water resource scarcity and pollution. However, existing water treatment techniques such as adsorption have been used successfully to control water pollution. This process is commonly employed in water treatment and among it is one of the water treatment technologies. Additionally, an increase in the hazardous chemicals in processed water due to the introduction of some chemically synthesized or commercial adsorbents suggests the need for research extension to green adsorption process. The unique properties of green adsorbent, such as adjustable particle size, excessive active sites, high chemical stability, cost-effectiveness, efficiency, bioavailability, and environmentally friendliness promote its usage. Subsequently, this study elucidated the types of green adsorbents, the advantages and limitations of the existing synthesis routes and their performances in water treatment applications. The limitation in the large-scale production of green adsorbents for real industrial applications and their reusability of spent adsorbent is also highlighted. Overall, the future development of green-based adsorbents for real industrial applications is discussed.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"8 ","pages":"Article 100338"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143161345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surface-modified ZnO nanoparticles for enhanced environmental and biomedical performance","authors":"Munisha Mahajan ,&nbsp;Ramandeep Kaur ,&nbsp;Jyoti Gaur ,&nbsp;Sanjeev Kumar ,&nbsp;Sandeep Kaushal ,&nbsp;Harpreet Kaur ,&nbsp;Amardeep Bajwa ,&nbsp;Anil Kumar Nainawat ,&nbsp;Gurjinder Singh","doi":"10.1016/j.hybadv.2024.100342","DOIUrl":"10.1016/j.hybadv.2024.100342","url":null,"abstract":"<div><div>The present study explores the synthesis of <em>cetyltrimethylammonium bromide</em>-modified zinc oxide nanoparticles (CTAB: ZnO NPs) via a precipitation-cum-hydrothermal route, optimizing their multifunctional capabilities for photocatalytic dye degradation and antibacterial applications. The synthesized ZnO NPs exhibit a wurtzite hexagonal structure, as confirmed by X-ray diffraction (XRD), with an average crystallite size of 47.12 nm, refined through Williamson-Hall (107.8 nm) and modified Debye-Scherrer (41 nm) analyses to account for lattice strain effects. UV–visible spectroscopy reveals a sharp absorption peak at 430 nm, with a corresponding band gap of 3.2 eV, indicative of strong quantum confinement effects. High-resolution transmission electron microscopy (HRTEM) and field emission scanning electron microscopy (FESEM) confirm the quasi-spherical morphology with minimal agglomeration, while energy-dispersive X-ray spectroscopy (EDX) validates the purity of the ZnO composition. Photocatalytic investigations demonstrate a remarkable degradation efficiency of 100 % for reactive blue-81 (RB-81) dye under UV irradiation within 1.3 h, with a kinetic reaction rate of 5.71 × 10² μmol g⁻¹ h⁻¹. Quantum yield (QY) and space-time yield (STY) values of 2.53 × 10⁻⁴ molecules photon⁻¹ and 1.27 × 10⁻⁵ molecules photon⁻¹ mg⁻¹, respectively, highlight the superior photonic utilization efficiency compared to conventional TiO₂-based photocatalysts. Antibacterial studies using the agar well diffusion method reveal significant inhibition zones of up to 3.42 cm and 2.14 cm for <em>Staphylococcus aureus</em> and <em>Pseudomonas aeruginosa</em>, respectively, demonstrating potent antibacterial activity. The findings indicate that CTAB: ZnO NPs not only enhance photocatalytic degradation and antibacterial efficacy but also offer scalable potential for environmental remediation and biomedical applications.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"8 ","pages":"Article 100342"},"PeriodicalIF":0.0,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143162022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of air content on rheological behavior and segregation of self-compacting concrete","authors":"Ferdaous Aghziel Sadfa ,&nbsp;Mouhcine Ben Aicha ,&nbsp;Olivier Jalbaud ,&nbsp;Mounir Zaher ,&nbsp;Adil Hafidi Alaoui ,&nbsp;Yves Burtschell","doi":"10.1016/j.hybadv.2024.100337","DOIUrl":"10.1016/j.hybadv.2024.100337","url":null,"abstract":"<div><div>Self-compacting concrete (SCC) offers significant advantages due to its low yield stress and plastic viscosity, yet challenges such as bleeding and segregation can compromise its stability. Maintaining a uniform aggregate distribution is essential to prevent these issues. Air-entraining admixtures (AEA) are often used to introduce air bubbles that enhance SCC's resilience in freeze-thaw conditions and potentially improve stability. This study addresses contradictions in prior research regarding the impact of entrained air on SCC's rheological behavior, experimentally evaluates the effects of varying air content on SCC's workability and segregation resistance, and establishes correlations between rheological characteristics and segregation stability. A comprehensive series of rheological tests, including slump flow diameter, flow time, blocking rate, segregation stability, plastic viscosity, yield stress, and segregation index, was conducted on SCC mixes with different AEA dosages. Regression models revealed significant correlations between air content and both the stability and workability of SCC, with results indicating that optimal AEA levels improve flowability and reduce segregation risks. These findings provide valuable insights into designing stable, high-performance SCC formulations tailored for challenging structural applications.</div></div>","PeriodicalId":100614,"journal":{"name":"Hybrid Advances","volume":"7 ","pages":"Article 100337"},"PeriodicalIF":0.0,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142722848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}