Gastroenterology & Endoscopy最新文献

{"title":"Efficacy and safety of EUS-guided cholecystolithotomy: A meta-analysis","authors":"Qian Yue ,&nbsp;Changqing Zhong ,&nbsp;Xin Huang ,&nbsp;Qiang Cai ,&nbsp;Lianyong Li","doi":"10.1016/j.gande.2023.05.003","DOIUrl":"https://doi.org/10.1016/j.gande.2023.05.003","url":null,"abstract":"<div><h3>Background</h3><p>The recurrence rate and readmission rate of patients with gallbladder stones and cholecystitis are high. Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is a new method for the treatment of cholecystitis in patients with high surgical risk. The acute symptoms can be relieved by drainage of bile, and cholecystolithotomy or polyp resection can be performed through a stent or fistula.</p></div><div><h3>Aims</h3><p>This article introduced the technique of EUS-guided cholecystolithotomy and conducted a meta-analysis evaluating its feasibility and safety.</p></div><div><h3>Methods</h3><p>Four electronic databases including SinoMed, CNKI, Wanfang Data, and PubMed were researched from inception to June 2022. Two researchers independently carried out literature screening and the data relevant to success rate and safety of per-oral cholecystoscopy were extracted for further meta-analysis by R Programming Language.</p></div><div><h3>Results</h3><p>A total of 7 studies with 129 patients were included in the present analysis. The results showed that the technical success rate of endoscopic ultrasonography-guided cholecystolithotomy was 97% [95%CI (92%-99%)], the clinical success rate was 93% [95%CI (87%–96%)]. The total adverse event rates were 34% [95% CI (14%–63%)]. Subgroup analysis of four major individual adverse events was fever 11.91% [95% CI (2.05%–46.62%)], peritonitis 2.33% [95% CI (0.75%–6.96%)], bleeding 4.37% [95% CI (0.72%–22.34%)], and abdominal pain 0.91% [95% CI (0.02%–26.38%)]. The adverse events were mild and recovered after conservative treatment.</p></div><div><h3>Conclusion</h3><p>EUS-guided cholecystolithotomy is a safe and alternative treatment modality for patients with symptomatic cholecystolithiasis, with acceptable procedure related complications. However, due to the limited data, further well-designed studies are warranted prior to confident adoption of the novel method into clinical practice.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 3","pages":"Pages 125-129"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49884737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential applications of ChatGPT in endoscopy: Opportunities and limitations","authors":"Weifeng Li ,&nbsp;Jing Wang ,&nbsp;Yan Yan ,&nbsp;Peng Yuan ,&nbsp;Changqi Cao ,&nbsp;Shijie Li ,&nbsp;Qi Wu","doi":"10.1016/j.gande.2023.06.001","DOIUrl":"https://doi.org/10.1016/j.gande.2023.06.001","url":null,"abstract":"<div><p>ChatGPT is an artificial intelligence model that has the potential to revolutionize the field of endoscopy. It can rapidly summarize medical records, assist with diagnosis, provide patient communication support, and even understand endoscopic images. However, there are limitations, including the risk of inaccurate or inappropriate responses, privacy and security issues, and the potential to limit doctors' thinking. Further research and improvements are needed to ensure ChatGPT's safe use in the medical field. Overall, the potential benefits of ChatGPT in endoscopy are vast, and it has the ability to greatly improve the efficiency of diagnosis and treatment.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 3","pages":"Pages 152-154"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49884824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The application of chatbot in gastroenterology nursing","authors":"Yang Zhao ,&nbsp;Chao Gao ,&nbsp;Lu Zhang ,&nbsp;Xiaopei Gao ,&nbsp;Zheng Zhang","doi":"10.1016/j.gande.2023.07.003","DOIUrl":"https://doi.org/10.1016/j.gande.2023.07.003","url":null,"abstract":"<div><h3>Objective</h3><p>The advent of large language models has triggered a wave of technological advancements in the global AI dialogue system, which has been widely adopted in various fields including medical care. This research aims to investigate the potential of chatbots in the field of gastroenterology nursing.</p></div><div><h3>Methods</h3><p>Two nurses compiled and categorized 20 relevant questions related to gastroenterology nursing, grouping them into four modules. Two chatbot-based AI language models were selected to answer all the questions. The satisfaction levels and satisfaction rates for each module were analyzed to evaluate the performance of the two chatbots.</p></div><div><h3>Results</h3><p>Chatbot A received an overall satisfaction rate of 85% (with 9 very satisfied, 8 satisfied, and 3 dissatisfied responses), while chatbot B had a lower satisfaction rate of 45% (with 0 very satisfied, 9 satisfied, and 11 dissatisfied responses). The satisfaction rates for module 1 (pre-hospital care) were 60% for chatbot A and 20% for chatbot B. In module 2 (health education during hospitalization), chatbot A's satisfaction rate was 100%, while chatbot B's satisfaction was only 60%. For module 3 (continuing care after discharge), chatbot A's satisfaction rate was 100%, while chatbot B's was 40%. Finally, in module 4 (nursing management), chatbot A received an 80% satisfaction rate, compared to chatbot B's 60% satisfaction rate.</p></div><div><h3>Conclusion</h3><p>The performance of chatbot in terms of health education and nursing management for patients during hospitalization is acceptable; Further optimization is needed in terms of pre hospitalization nursing interventions and post discharge continuity care. The performance of different chatbots varies, and intelligent large models need to be tailored to the medical or nursing fields to better apply in the field of digestive disease care.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 3","pages":"Pages 136-138"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49884831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of chatbots on gastroenterology: Let's chat about the future","authors":"Lianyong Li","doi":"10.1016/j.gande.2023.06.002","DOIUrl":"https://doi.org/10.1016/j.gande.2023.06.002","url":null,"abstract":"<div><p>New chatbot models, built on the transformer architecture and trained on large amounts of data, have the potential to transform healthcare, including gastroenterology. In this paper, we synthesized current literature reports on the roles of chatbots, and evaluated their potential applications in various areas such as clinical diagnosis and treatment plans, patient triage, scientific research, and academic writing. We believe that chatbots can improve efficiency and patient outcomes in these fields. However, it is important to acknowledge some challenges that need to be addressed, such as privacy concerns and emotional considerations. Overall, chatbots are expected to have a significant influence on gastroenterology and require more research to comprehensively examine their capabilities.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 3","pages":"Pages 144-149"},"PeriodicalIF":0.0,"publicationDate":"2023-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49884826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chinese consensus on multidisciplinary diagnosis and treatment of gastroesophageal reflux disease 2022","authors":"Zhiwei Hu ,&nbsp;Jimin Wu ,&nbsp;Zhonggao Wang ,&nbsp;The Consensus Committee ,&nbsp;Members of the Expert Group of the Consensus (ordered alphabetically by the pinyin of surnames),&nbsp;Xinghua Bai ,&nbsp;Yu Lan ,&nbsp;Kefang Lai ,&nbsp;Abudureyimu Kelimu ,&nbsp;Feng Ji ,&nbsp;Zhenling Ji ,&nbsp;Diyu Huang ,&nbsp;Zhiwei Hu ,&nbsp;Xiaohua Hou ,&nbsp;Jianyu Hao ,&nbsp;Zhining Fan ,&nbsp;Xiaoping Chen ,&nbsp;Dong Chen ,&nbsp;Shengliang Chen ,&nbsp;Jinrang Li ,&nbsp;Duowu Zou","doi":"10.1016/j.gande.2023.01.001","DOIUrl":"https://doi.org/10.1016/j.gande.2023.01.001","url":null,"abstract":"","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 2","pages":"Pages 33-86"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of therapeutic targets and prognostic biomarkers among CC chemokines in the pancreatic adenocarcinoma microenvironment","authors":"Xinyuan Liu,&nbsp;Qi Zhang,&nbsp;Tao Mao,&nbsp;Congcong Min,&nbsp;Jing Guo,&nbsp;Cuiping Zhang,&nbsp;Zibin Tian,&nbsp;Xiaoyu Li","doi":"10.1016/j.gande.2022.11.006","DOIUrl":"https://doi.org/10.1016/j.gande.2022.11.006","url":null,"abstract":"<div><p>Pancreatic adenocarcinoma (PAAD), one of the most aggressive and lethal malignant tumors, is correlated with increased morbidity and mortality. CC chemokines can modulate the infiltration of immune cells and affect the clinical outcome of cancer patients. However, the therapeutic potential and prognostic value of CC chemokines in PAAD have not yet been elucidated. To do this, we comprehensively explore and analyze large amounts of data base on ONCOMINE, UALCAN, GEPIA2, LinkedOmics, Kaplan-Meier Plotter, cBioPortal, GeneMANIA, DAVID 6.8, TRRUST, TIMER, TISIDB, DGIdb, and TTD. We found the transcriptional levels of CCL5/7/13/15/18/19/20 in PAAD tissues were remarkably increased, whereas the transcriptional level of CCL17 was decreased. CCL20 expression had significantly been correlated with the tumor stage of PAAD patients. High expressions of CCL5, CCL7, CCL13, CCL18, and CCL20 were notably correlated with the prognosis of patients. Moreover, patients with CCL18 and CCL19 alterations showed a poor prognosis in both overall survival (OS) and disease-specific survival (DSS). Patients with CCL5 and CCL15 alterations also presented a poor prognosis in OS. The key transcription factors for CC chemokines are RELA and NF-κB1. The functions of the differentially expressed CC chemokines were mainly correlated the chemokine signaling pathway, cytokine-cytokine receptor interaction, NF-kappa B signaling pathway, and so forth. We also discovered significant associations between the expression levels of CC chemokines and six infiltrating immune cells including, CD8⁺ T cells, CD4⁺ T cells, B cells, macrophages, neutrophils, and dendritic cells. The drug-gene interactions and related miRNAs of aberrant expression CC chemokines were also explored. Our study indicated the correlation between CC chemokines and PAAD and clarified the value of differentially expressed CC chemokines as potential therapeutic targets and prognostic markers for PAAD.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 2","pages":"Pages 91-101"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ischemic colitis after receipt of COVID-19 vaccine: Causative or coincidence?","authors":"Xin Huang ,&nbsp;Jihua Wu ,&nbsp;Changqing Zhong","doi":"10.1016/j.gande.2023.04.001","DOIUrl":"https://doi.org/10.1016/j.gande.2023.04.001","url":null,"abstract":"","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 2","pages":"Pages 118-119"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49860991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-induced liver injury: An overview and update","authors":"Yujie Wang,&nbsp;Wen Xie","doi":"10.1016/j.gande.2022.11.005","DOIUrl":"https://doi.org/10.1016/j.gande.2022.11.005","url":null,"abstract":"<div><p>Drug-induced liver injury (DILI) is a relatively rare but important adverse event for a variety of commonly used drugs, herbal and dietary supplements, illegal drugs and novel agents. The actual epidemiology of DILI is difficult to evaluate and varies between different countries. Many risk factors have been identified for DILI but the exact and detailed mechanisms of DILI still remain largely unknown. DILI has been typically classified as direct or idiosyncratic, but indirect injury has been recognized as the third type of DILI. It is difficult to predict and prevent DILI due to the lack of acute diagnosis tools. Many novel serum biomarkers have been identified for DILI and need further study in the clinic. For management, discontinuation of suspicious drugs is the first and important step. Effective drugs treatment is limited but novel drugs have been explored. Novel drugs, such as immune checkpoint inhibitors and monoclonal antibodies, have emerging as important causative agents of DILI. This paper reviewed the epidemiology, risk factors, pathogenesis, clinical presentation, causative agents, diagnosis and management of DILI.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 2","pages":"Pages 102-109"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of esophageal varices in patients with hepatitis B-associated liver cirrhosis by non-invasive markers","authors":"Lili Gao,&nbsp;Yijin Zhang,&nbsp;Xuesong Gao,&nbsp;Li Xu,&nbsp;Xuefei Duan","doi":"10.1016/j.gande.2023.02.002","DOIUrl":"https://doi.org/10.1016/j.gande.2023.02.002","url":null,"abstract":"<div><h3>Aims</h3><p>To assess the non-invasive markers for diagnosing and grading esophageal varices(EV) in hepatitis B-associated liver cirrhosis by non-invasive method.</p></div><div><h3>Methods</h3><p>A total of 209 treatment-naive patients with hepatitis B-associated liver cirrhosis were included in this study. These patients were divided into no EV, large grade EV and any grade EV groups according to electronic gastroscope (EGD) results. Blood tests, physical examination, and abdominal ultrasound scan (USS) were measured. The non-invasive indexes for predicting esophageal varices were screened, and non conditional logistic regression model was established. Performance was expressed as sensitivity, specificity, positive, and negative predictive values (PPV, NPV), accuracy, and area under the curve (AUC).</p></div><div><h3>Results</h3><p>In the 209 patients, 155 (74.2%) EV and 106(50.7%) large EV were found. There were significant differences in spleen-length (SL), portal vein diameter (PVD), platelet blood cell (PLT) and white blood cell (WBC) between patients with any grade or large and without EV by univariate analysis. The logistic regression model was Y=-2.083-0.011∗PLT+0.101∗PVD+0.013∗SL with any grade EV, the prediction formula is Y= ​0.427-0.013∗PLT -0.861∗WBC+0.008∗SL with large EV.</p></div><div><h3>Conclusions</h3><p>Spleen-length, portal vein diameter, platelet and white blood cell can predict esophageal varices and large esophageal varices in hepatitis B-associated liver cirrhosis.</p></div>","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 2","pages":"Pages 87-90"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49885376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case report: Chronic hepatitis C with anti-HCV positive and serum HCV RNA negative","authors":"Huihui Lu ,&nbsp;Wen Deng ,&nbsp;Yao Lu ,&nbsp;Lu Zhang ,&nbsp;Yao Xie ,&nbsp;Minghui Li","doi":"10.1016/j.gande.2022.11.004","DOIUrl":"https://doi.org/10.1016/j.gande.2022.11.004","url":null,"abstract":"","PeriodicalId":100571,"journal":{"name":"Gastroenterology & Endoscopy","volume":"1 2","pages":"Pages 120-123"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49860257","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}