Chemical record最新文献

{"title":"Advancements in Desilylation Reactions for the Synthesis of Valuable Organic Molecules","authors":"Chuang Liu,&nbsp;Dr. Le Zhang,&nbsp;Qingqing You,&nbsp;Prof. Huangdi Feng,&nbsp;Prof. Junhai Huang","doi":"10.1002/tcr.202400120","DOIUrl":"10.1002/tcr.202400120","url":null,"abstract":"<p>Silicon, due to its abundance, non-toxicity, and cost-effectiveness, is a critical element in the earth's crust with significant industrial applications. In organic chemistry, main group elements, and in particular silicon, are extensively utilized as versatile synthetic intermediates. Despite the current challenges associated with harsh reaction conditions and unsustainable practices in synthesizing crucial organic structural molecules, desilylation reactions have emerged as a facilitative method, offering milder conditions and operational simplicity. This review provides a comprehensive analysis of recent advancements in the synthesis of valuable organic molecules through two distinct desilylation reactions. It systematically presents the synthesis of a variety of derivatives, such as furan, alcohol, N-heterocyclic, and ketone, highlighting the broad substrate tolerance of these reactions. This broad functional group compatibility suggests a promising future for the synthesis of a wide range of bioactive molecules, underscoring the significant potential of desilylation in contemporary organic synthesis.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 11","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Progress on NHC-Catalyzed 1,6-Conjugate Addition Reactions","authors":"Prof. Jun Sun,&nbsp;Prof. Shichun Jiang,&nbsp;Prof. Yonggui Liu,&nbsp;Ling Pan,&nbsp;Prof. Ying-Guo Liu,&nbsp;Prof. Bing Zeng","doi":"10.1002/tcr.202400125","DOIUrl":"10.1002/tcr.202400125","url":null,"abstract":"<p>As a significant variant of the Michael reaction, the 1,6-addition reaction has undergone considerable development over the past decade. This effective strategy enables the synthesis of a variety of novel and potentially bioactive functional molecules. In this review, we summarize the recent progress in NHC-catalyzed 1,6-addition reactions, highlighting their efficiency in the rapid synthesis of complex functional molecules. We also provide our perspectives on the future development of this dynamic and highly active research area.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 11","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Review on the Synthesis of [1,2,3]Triazolo[1,5-a]Quinolines","authors":"Gabriel P. Da Costa,&nbsp;Manoela Sacramento,&nbsp;Prof. Angelita M. Barcellos,&nbsp;Prof. Dr. Diego Alves","doi":"10.1002/tcr.202400107","DOIUrl":"10.1002/tcr.202400107","url":null,"abstract":"<p>This report outlines the evolution and recent progress about the different protocols to synthesize the <i>N</i>-heterocycles fused hybrids, specifically [1,2,3]triazolo[1,5-<i>a</i>]quinoline. This review encompasses a broad range of approaches, describing several reactions for obtaining this since, such as dehydrogenative cyclization, oxidative <i>N</i>−<i>N</i> coupling, Dieckmann condensation, intramolecular Heck, (3+2)-cycloaddition, Ullman-type coupling and direct intramolecular arylation reactions. We divided this review in three section based in the starting materials to synthesize the target [1,2,3]triazolo[1,5-<i>a</i>]quinolines. Starting materials containing quinoline or triazole units previously formed, as well as starting materials which both quinoline and triazole units are formed in situ. Different methods of obtaining are described, such as metal-free or catalyzed conditions, azide-free, using conventional heating or alternative energy sources, such as electrochemical and photochemical methods. Mechanistic insights underlying the reported reactions were also described in this comprehensive review.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 11","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142459334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Stimuli-Responsive Transformable Supramolecular Nanotubes","authors":"","doi":"10.1002/tcr.202400189","DOIUrl":"10.1002/tcr.202400189","url":null,"abstract":"<p>N. Kameta, “Stimuli-Responsive Transformable Supramolecular Nanotubes,” <i>The Chemical Record</i> 22, no. 6 (2022): e202200025, https://doi.org/10.1002/tcr.202200025.</p><p>The above article, published online on 04 March 2022 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the author, Naohiro Kameta; the journal Editor-in-Chief, Keiji Maruoka; The Chemical Society of Japan; and Wiley-VCH GmbH, Weinheim. The retraction has been agreed upon following an investigation into concerns raised by National Institute of Advanced Industrial Science and Technology (AIST), and also requested by the author due to image falsification in electron microscopy images. In Figures 7e, and 11c, where the author falsified incorrect scale bars and inappropriately manipulated the image content; in Figures 2c, 5c, 6c, 6d, 8d, and 8e, where the author carelessly placed incorrect scale bars; all affecting the interpretation of the data and research results presented.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 12","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tcr.202400189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142399564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catalysts for Liquid Organic Hydrogen Carriers (LOHCs): Efficient Storage and Transport for Renewable Energy","authors":"Huda S. Alghamdi,&nbsp;Ahsan Ali,&nbsp;Afnan M. Ajeebi,&nbsp;Abdesslem Jedidi,&nbsp;Mohammed Sanhoob,&nbsp;Mahbuba Aktary,&nbsp;A. H. Shabi,&nbsp;Mohammad Usman,&nbsp;Wasan Alghamdi,&nbsp;Shahad Alzahrani,&nbsp;Md. Abdul Aziz,&nbsp;Dr. M. Nasiruzzaman Shaikh","doi":"10.1002/tcr.202400082","DOIUrl":"10.1002/tcr.202400082","url":null,"abstract":"<p>Restructuring the current energy industry towards sustainability requires transitioning from carbon based to renewable energy sources, reducing CO₂ emissions. Hydrogen, is considered a significant clean energy carrier. However, it faces challenges in transportation and storage due to its high reactivity, flammability, and low density under ambient conditions. Liquid organic hydrogen carriers offer a solution for storing hydrogen because they allow for the economical and practical storage of organic compounds in regular vessels through hydrogenation and dehydrogenation. This review evaluates several hydrogen technologies aimed at addressing the challenges associated with hydrogen transportation and its economic viablity. The discussion delves into exploring the catalysts and their activity in the context of catalysts′ development. This review highlights the pivotal role of various catalyst materials in enhancing the hydrogenation and dehydrogenation activities of multiple LOHC systems, including benzene/cyclohexane, toluene/methylcyclohexane (MCH), N-ethylcarbazole (NEC)/dodecahydro-N-ethylcarbazole (H12-NEC), and dibenzyltoluene (DBT)/perhydrodibenzyltoluene (H18-DBT). By exploring the catalytic properties of noble metals, transition metals, and multimetallic catalysts, the review provides valuable insights into their design and optimization. Also, the discussion revolved around the implementation of a hydrogen economy on a global scale, with a particular focus on the plans pertaining to Saudi Arabia and the GCC (Gulf Cooperation Council) countries. The review lays out the challenges this technology will face, including the need to increase its H₂ capacity, reduce energy consumption by providing solutions, and guarantee the thermal stability of the materials.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 11","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fundamental and Practical Aspects of Break-In/Conditioning of Proton Exchange Membrane Fuel Cells","authors":"Mitja Kostelec,&nbsp;Matija Gatalo,&nbsp;Nejc Hodnik","doi":"10.1002/tcr.202400114","DOIUrl":"10.1002/tcr.202400114","url":null,"abstract":"<p>Proton exchange membrane fuel cells (PEMFCs) have proven to be a promising power source for various applications ranging from portable devices to automotive and stationary power systems. The production of PEMFC involves numerous stages in the value chain, with each stage presenting unique challenges and opportunities to improve the overall performance and durability of the PEMFC stack. These include steps such as manufacturing the key components such as the platinum-based catalyst, processing these components into the membrane electrode assemblies (MEAs), and stacking the MEAs to ultimately produce a PEMFC stack. However, it is also known that the break-in or conditioning phase of the stack plays a crucial role in the final performance as well as durability. It involves several key phenomena such as hydration of the membrane, swelling of the ionomer, redistribution of the catalyst and the creation of suitable electrochemical interfaces – establishment of the triple phase boundary. These improve the proton conductivity, the mass transport of reactants and products, the catalytic activity of the electrode and thus the overall efficiency of the FC. The cruciality of break-in is demonstrated by the improvement in performance, which can even be over 50 % compared to the initial state. The state-of-the-art approach for the break-in of MEAs involves an electrochemical protocol, such as voltage cycling, using a PEMFC testing station. This method is time-consuming, equipment-intensive, and costly. Therefore, new, elegant, and cost-effective solutions are needed. Nevertheless, the primary aim is to achieve maximum/optimal performance so that it is fully operational and ready for the market. It is therefore essential to better understand and deconvolute these complex mechanisms taking place during break-in/conditioning. Strategies include controlled humidity and temperature cycling, novel electrode materials and other advanced break-in methods such as air braking, vacuum activation or steaming. In addition, it is critical to address the challenges associated with standardisation and quantification of protocols to enable interlaboratory comparisons to further advance the field.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 10","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tcr.202400114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142388470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Feature: Application of 2-Azabicyclo[2.2.1]Hept-5-En-3-One (Vince Lactam) in Synthetic Organic and Medicinal Chemistry (Chem. Rec. 9/2024)","authors":"Dr. Melinda Nonn,&nbsp;Prof. Santos Fustero,&nbsp;Prof. Loránd Kiss","doi":"10.1002/tcr.202480902","DOIUrl":"https://doi.org/10.1002/tcr.202480902","url":null,"abstract":"<p>The cover picture shows the structure of some three-dimensional small molecular entities, such as highly-functionalized cyclopentanes and saturated azaheterocycles with multiple chiral centers, derived by chemical manipulations of Vince lactam. More details can be found in article number e2024000070 by Melinda Nonn, Santos Fustero, and Loránd Kiss. (DOl: 10.1002/tcr.202400070.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 9","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tcr.202480902","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142324625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cover Picture: Recent Developments in the Fabrication and Application of Superhydrophobic Suraces (Chem. Rec. 9/2024)","authors":"Ting Li,&nbsp;Yi Peng.,&nbsp;Hang You,&nbsp;Xiaoya Guan,&nbsp;Jin Lv,&nbsp;Chong Yang","doi":"10.1002/tcr.202480901","DOIUrl":"https://doi.org/10.1002/tcr.202480901","url":null,"abstract":"<p>Front Cover: The cover shows the application status of superhydrophobic surfaces in combination with micro-nano structure and photodynamic capabilities in the field of antimicrobials. A similar combination of active and passive protection strategies is becoming possible in superhydrophobic surface applications. More details can be found in article number e202400065 by Ting Li, Yi Peng, and co-workers. (DOl: 10.1002/tcr.202400065.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure>\u0000 </p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 9","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tcr.202480901","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142324624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Built-In Electric Field Boost Photocatalytic Degradation of Pollutants in Wastewater","authors":"Yang Yu,&nbsp;Zhiyong Qiao,&nbsp;Changming Ding","doi":"10.1002/tcr.202400106","DOIUrl":"10.1002/tcr.202400106","url":null,"abstract":"<p>The photocatalysis technique shows significant potential for wastewater degradation; however, the rapid recombination of photogenerated holes and electrons severely limits its photocatalytic efficiency. This situation necessitates the development of effective strategies to tackle these challenges. One well-documented approach is built-in electric field engineering in heterojunctions or composites, which has been shown to enhance electron transfer and thereby reduce the recombination of electrons and holes. This strategy has proven highly effective in significantly improving photocatalytic activity for the degradation of pollutants in wastewater. In this context, we summarize recent advancements in built-in electric field engineering in photocatalysts, highlighting the fundamentals and modifications of this approach, as well as its positive impact on photocatalytic performance in the degradation of wastewater pollutants.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 10","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiology, Pathophysiology and Clinical Relevance of D-Amino Acids Dynamics: From Neurochemistry to Pharmacotherapy","authors":"M. Verónica Donoso,&nbsp;Vicente Catalán-Salas,&nbsp;Raúl Pulgar-Sepúlveda,&nbsp;Jaime Eugenín,&nbsp;J. Pablo Huidobro-Toro","doi":"10.1002/tcr.202400013","DOIUrl":"10.1002/tcr.202400013","url":null,"abstract":"<p>Over three decades ago, two independent groups of investigators identified free D-aspartic and later D-serine in specific brain nuclei and endocrine glands. This finding revealed a novel, non-proteinogenic role of these molecules. Moreover, the finding that aged proteins from the human eye crystallin, teeth, bone, blood vessels or the brain incorporate D-aspartic acids to specific primary protein sequences fostered the hypothesis that aging might be related to D-amino acid isomerization of body proteins. The experimental confirmation that schizophrenia and neurodegenerative diseases modify plasma free D-amino acids or tissue levelsnurtured the opportunity of using D-amino acids as therapeutic agents for several disease treatments, a strategy that prompted the successful current application of D-amino acids to human medicine.</p>","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"24 10","pages":""},"PeriodicalIF":7.0,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142342676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}