Chemical record最新文献

5'-O-P-N Linkages of Phosphoramidate Nucleotides: Chemical Construction and Biological Impact. 磷酰胺核苷酸的5'-O-P-N键：化学结构和生物学影响。

IF 7 2区化学

Chemical record Pub Date : 2025-05-29 DOI: 10.1002/tcr.202500056

Arka Das, Rana Saha, Kaushal Naithani, Krutika Sonar, Christine Jonathan, Subhendu Bhowmik

{"title":"5'-O-P-N Linkages of Phosphoramidate Nucleotides: Chemical Construction and Biological Impact.","authors":"Arka Das, Rana Saha, Kaushal Naithani, Krutika Sonar, Christine Jonathan, Subhendu Bhowmik","doi":"10.1002/tcr.202500056","DOIUrl":"https://doi.org/10.1002/tcr.202500056","url":null,"abstract":"The development of chemically modified nucleotides has been a transformative area of research, driving innovations in medicinal chemistry, prebiotic chemistry, and nucleic acid-based therapeutics. Among these modifications, 5'-O-P-N phosphoramide nucleotides represent an emerging class of nucleotide analogs featuring a phosphoramidate (P-N) linkage at the 5'-hydroxyl position. This structural alteration significantly influences their chemical reactivity, enzymatic stability, and biological function, making them valuable tools for drug design, nucleotide-based enzymatic studies, and synthetic biology applications. In this review, we explore the synthetic methodologies employed for constructing 5'-O-P-N linkages, including phosphoramidation strategies, catalytic approaches, and emerging green chemistry techniques. Additionally, this study discusses the biological implications of these modifications, focusing on their role in nucleotide metabolism, enzyme interactions, and potential as antiviral and anticancer agents. Finally, it highlights current challenges, future directions, and the expanding scope of phosphoramide nucleotides in medicinal chemistry and biotechnology.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e2500056"},"PeriodicalIF":7.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Innovative Electrochemical Sensors for Pesticide Residue Detection: Nanomaterials, Miniaturization, and Intelligent Data Analysis. 用于农药残留检测的创新电化学传感器：纳米材料、小型化和智能数据分析。

IF 7 2区化学

Chemical record Pub Date : 2025-05-29 DOI: 10.1002/tcr.202500070

Yu Han, Lin Zhu, Ruiming Wen, Jianjun Liao, Bei Li, Long Wu

{"title":"Innovative Electrochemical Sensors for Pesticide Residue Detection: Nanomaterials, Miniaturization, and Intelligent Data Analysis.","authors":"Yu Han, Lin Zhu, Ruiming Wen, Jianjun Liao, Bei Li, Long Wu","doi":"10.1002/tcr.202500070","DOIUrl":"https://doi.org/10.1002/tcr.202500070","url":null,"abstract":"The increasing use of pesticides in agriculture has raised concerns over their residues in food products, necessitating the development of effective detection methods to ensure consumer safety and environmental sustainability. This review covers cutting- edge advances in electrochemical sensors for pesticide residue detection, emphasizing their significance in addressing the limitations of traditional methods. The authors summarize recent progress in sensor materials for enhancing detection sensitivity and selectivity, including metal-organic frameworks, single-atom materials, MXene-based materials, and conductive polymers and so on. The review highlights the progress in sensor miniaturization and portability, enabling on-site and real-time monitoring through the integration with microfluidic devices and wearable technology. It discusses the challenges and strategies for simultaneous detection of multiple pesticide residues to enhance efficiency. The influence of environmental factors on sensor performance is analyzed, and adaptive technologies are proposed to stabilize sensor performance under varying conditions. Moreover, the integration of big data and artificial intelligence in electrochemical sensing is examined, showing its potential in intelligent data analysis and automation. The review concludes by identifying the current challenges and future directions in electrochemical sensing for pesticide residues, suggesting that innovative sensor technologies hold the promise of transforming food safety monitoring and environmental protection.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e2500070"},"PeriodicalIF":7.0,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179862","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Catalytic Enantioselective Access to Planar-Chiral Macrocyclophanes. 平面手性大环烷的催化对映选择性制备。

IF 7 2区化学

Chemical record Pub Date : 2025-05-29 DOI: 10.1002/tcr.202500085

Lei Yang, Yan-Ping Zhang, Yong You, Zhen-Hua Wang, Wei-Cheng Yuan, Jian-Qiang Zhao

引用次数: 0

Cover Picture: Advances in the Synthetic Utility of Difluorocarbene Generated from TMSCF3 (Ruppert-Prakash Reagent) and Its Derivatives (Chem. Rec. 5/2025) 封面图：TMSCF3 （Ruppert-Prakash试剂）及其衍生物合成二氟烃的研究进展。Rec。5/2025)

IF 7 2区化学

Chemical record Pub Date : 2025-05-12 DOI: 10.1002/tcr.202580501

Dr. Jagadeesh Krishnan, Mr. Kaja Sahib, Ms. Keerthana G. Nair, Mr. Arshad Jouhar T, Dr. Rony Rajan Paul

引用次数: 0

Transition Metal-Catalyzed Aminocarbonylation Reactions. 过渡金属催化氨基羰基化反应。

IF 7 2区化学

Chemical record Pub Date : 2025-05-08 DOI: 10.1002/tcr.202500029

Fatemeh Doraghi, Mohammad Hossein Morshedsolouk, Niki Raisi, Tolou Hosseinifar, Milad Noori, Bagher Larijani, Mohammad Mahdavi

引用次数: 0

Recent Representative Progress of Surface Coating Technology. 表面涂层技术的代表性进展。

IF 7 2区化学

Chemical record Pub Date : 2025-05-08 DOI: 10.1002/tcr.202500054

Haoran Sun, Bohan Song, Xiaomin Sun, Xinqi Cui, Zexian Liu, Meng Cong, Mingyuan Sun, Zimeng Zhu, Yuchuan Tian, Shuyu Liu, Ping Xu, Bing Dai, Lei Wang

{"title":"Recent Representative Progress of Surface Coating Technology.","authors":"Haoran Sun, Bohan Song, Xiaomin Sun, Xinqi Cui, Zexian Liu, Meng Cong, Mingyuan Sun, Zimeng Zhu, Yuchuan Tian, Shuyu Liu, Ping Xu, Bing Dai, Lei Wang","doi":"10.1002/tcr.202500054","DOIUrl":"https://doi.org/10.1002/tcr.202500054","url":null,"abstract":"Surface coating technologies have become fundamental in modern industrial development, offering effective methods to enhance material surface properties while maintaining bulk characteristics. These technologies span from traditional methods like electroplating to advanced techniques such as physical vapor deposition (PVD), chemical vapor deposition (CVD), and atomic layer deposition (ALD), serving crucial functions in corrosion protection, wear resistance, and various specialized applications across industries. The field has witnessed significant advancement in both process sophistication and application scope, driven by increasing demands for enhanced material performance and environmental sustainability. The integration of nanotechnology and smart materials has led to the development of multifunctional coatings with unprecedented properties, while emerging technologies (such as smart manufacturing and biomedical coatings) like cold spray and biomimetic surface modification continue to expand the possibilities for surface engineering applications. Bearing it in mind, we would like to offer a timely and concisely summary for the recent representative progress of surface coating technology, hoping to provide basic understanding and fundamental guidance for the development of the field.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e202500054"},"PeriodicalIF":7.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143975164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Gold-Maker of Animal Oil and Prussian Blue Fame - The Chemical and Medicinal Science Philosophy of Johann Conrad Dippel. 动物油和普鲁士蓝名声的黄金制造者-约翰·康拉德·迪佩尔的化学和医学科学哲学。

IF 7 2区化学

Chemical record Pub Date : 2025-05-06 DOI: 10.1002/tcr.202500043

Curt Wentrup

{"title":"The Gold-Maker of Animal Oil and Prussian Blue Fame - The Chemical and Medicinal Science Philosophy of Johann Conrad Dippel.","authors":"Curt Wentrup","doi":"10.1002/tcr.202500043","DOIUrl":"https://doi.org/10.1002/tcr.202500043","url":null,"abstract":"Johann Conrad Dippel (1673-1734) was a theologian, a physician, and a (probably autodidactic) chemist. He had no viable scientific theory, dismissed atomism and relentlessly attacked the rational philosophies of Descartes, Spinoza, Hobbes, Leibniz, and Wolff as a radical Pietist, for whom body and mind constitute an inseparable whole. By implication he rejected Newton, but accepted Aristotle partially. He vehemently rejected Descartes' animal (man)-machine and therefore also Boerhaave's nervous machine. His claim of gold-making was the probable reason for his call to Berlin, where he prepared not gold but his animal pyrolysis oil (Dippel's oil) by pyrolysis of blood, leading to the co-discovery of Prussian blue. Later he made impossible promises of gold-making to Denmark's King Frederik IV. His wonder-balm was claimed to heal all wounds, including that caused by a nail hammered into a dog's skull. His phytomedicines were derived from Galen and Dioscorides; his chemical medicines from Paracelsus and Valentine. He denied the possibility of establishing general rules for medicine and did not express an opinion on the leading chemical theory, the phlogiston. In the absence of any plausible chemical and medicinal theories, Dippel relied on the almighty God, to guide him to produce gold and a medicinal arcanum.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e202500043"},"PeriodicalIF":7.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Nickel-Based Catalysts for Alkaline Water Electrolysis: Comprehensive Review of Current Research Direction for HER and OER Applications. 镍基碱性电解催化剂的研究进展：HER和OER应用研究方向综述。

IF 7 2区化学

Chemical record Pub Date : 2025-04-29 DOI: 10.1002/tcr.202500049

Ivana M Perović, Stefan D Mitrović, Snežana M Brković, Igor A Pašti

{"title":"Advances in Nickel-Based Catalysts for Alkaline Water Electrolysis: Comprehensive Review of Current Research Direction for HER and OER Applications.","authors":"Ivana M Perović, Stefan D Mitrović, Snežana M Brković, Igor A Pašti","doi":"10.1002/tcr.202500049","DOIUrl":"https://doi.org/10.1002/tcr.202500049","url":null,"abstract":"Nickel-based catalysts are among the most promising materials for electrocatalytic water splitting, particularly for the hydrogen evolution reaction (HER) and oxygen evolution reaction (OER) in alkaline media. Their abundance, cost-effectiveness, and tunable electrochemical properties make them attractive alternatives to precious metal catalysts. This review provides a comprehensive analysis of the advancements in nickel-based catalysts, including pure nickel, alloys, oxides, hydroxides, and spinels, emphasizing their synthesis methods, structural properties, and electrocatalytic performance. Recent nanostructuring, doping, and hybridization innovations with conductive supports have significantly enhanced catalytic activity, stability, and efficiency. Despite notable progress, challenges remain in improving long-term durability, minimizing surface degradation, and scaling up production for industrial applications. Addressing these limitations through advanced catalyst design, in situ characterization, and integration with renewable energy sources will be crucial for widely adopting nickel-based catalysts in sustainable hydrogen production. This review highlights the key developments and future directions in the field, underscoring the role of nickel-based materials in enabling the hydrogen economy and global decarbonization efforts.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e202500049"},"PeriodicalIF":7.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transition Metal-Catalyzed Direct Functionalization of Carbazoles. 过渡金属催化咔唑的直接功能化。

IF 7 2区化学

Chemical record Pub Date : 2025-04-29 DOI: 10.1002/tcr.202500042

Vikash Kumar, Sivakumar Sudharsan, Lusina Mantry, Rajaram Maayuri, Malati Das, Parthasarathy Gandeepan

{"title":"Transition Metal-Catalyzed Direct Functionalization of Carbazoles.","authors":"Vikash Kumar, Sivakumar Sudharsan, Lusina Mantry, Rajaram Maayuri, Malati Das, Parthasarathy Gandeepan","doi":"10.1002/tcr.202500042","DOIUrl":"https://doi.org/10.1002/tcr.202500042","url":null,"abstract":"Carbazoles are an important class of nitrogen-containing heterocycles found in diverse natural products, bioactive molecules, and functional materials. Their broader applications have driven extensive research into their synthesis and functionalization. Among various approaches, transition metal-catalyzed C-H activation has emerged as a powerful tool for direct functionalization, offering regioselectivity, efficiency, and sustainability. This review comprehensively summarizes advancements in transition metal-catalyzed C-H functionalization of carbazoles. Various catalytic systems employing palladium, ruthenium, rhodium, nickel, cobalt, copper, and iron have enabled alkylation, alkenylation, acylation, arylation, alkynylation, and heteroatom incorporation in carbazoles. These methodologies enabled late-stage diversification and have opened avenues for accessing structurally complex carbazole derivatives with tailored properties. The review aims to provide a comprehensive guide for researchers exploring carbazole functionalization via C-H activation, highlighting key mechanistic insights, scope, and emerging trends in this field.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e202500042"},"PeriodicalIF":7.0,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143978607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Electrocatalyzed Water Oxidation by Molecular Complexes of First Row Transition Metals. 第一行过渡金属分子配合物电催化水氧化研究进展。

IF 7 2区化学

Chemical record Pub Date : 2025-04-24 DOI: 10.1002/tcr.202400266

Chiara Lenzi, Andrea Masetti, Isacco Gualandi, Erika Scavetta, Luca Rigamonti, Rita Mazzoni

{"title":"Advances in Electrocatalyzed Water Oxidation by Molecular Complexes of First Row Transition Metals.","authors":"Chiara Lenzi, Andrea Masetti, Isacco Gualandi, Erika Scavetta, Luca Rigamonti, Rita Mazzoni","doi":"10.1002/tcr.202400266","DOIUrl":"https://doi.org/10.1002/tcr.202400266","url":null,"abstract":"Energy transition toward sustainable, alternative, and affordable solutions is likely to be one of the major challenges of the anthropocene era. The oxygen evolution reaction (OER) is a pivotal electrocatalytic process essential for advancing renewable energy conversion and storage technologies, including water splitting, artificial photosynthesis, metal-air batteries, and fuel cells. Electrocatalytic pathways can significantly reduce the overall energy requirements of these devices, particularly focusing on the energy demands associated with water splitting for hydrogen production. This review, after introducing the state of the art in heterogeneous catalysis, will be devoted to the description of molecular water oxidation electrocatalysts (MWOCs), focusing on the recent advancements on catalysts composed of various metals, including Mn, Co, Cu, Ni, and Fe, in combination with a range of mono- and multidentate ligands. Critical insights are presented and discussed to provide readers with suggestions for ligand design in assisted catalysis. These observations aim to identify synergistic solutions that could enhance technological maturity by reducing energy absorption while improving stability and efficiency.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":" ","pages":"e202400266"},"PeriodicalIF":7.0,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0