Chemical record最新文献_第2页

Preparation of Hydrophilic Polysilsesquioxanes and Their Applications as Water Separation and Antifogging Coating Materials 亲水性聚硅氧烷的制备及其在水分离和防雾涂料中的应用。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-23 DOI: 10.1002/tcr.70218

Takashi Hamada, Yohei Adachi, Joji Ohshita

{"title":"Preparation of Hydrophilic Polysilsesquioxanes and Their Applications as Water Separation and Antifogging Coating Materials","authors":"Takashi Hamada, Yohei Adachi, Joji Ohshita","doi":"10.1002/tcr.70218","DOIUrl":"10.1002/tcr.70218","url":null,"abstract":"Polysilsesquioxanes (PSQs) have been extensively studied as typical organic–inorganic hybrid materials that exhibit functionality and processability owing to organic substituents on silicon atoms, while also thermal and mechanical stability attributable to the inorganic siloxane (Si–O–Si) network structure. We describe herein the introduction of hydrophilic substituents into random PSQs to improve properties, such as water permeability and absorption capability, for developing reverse osmosis (RO) membranes for water separation and antifogging coating materials. Previously studied PSQ-based RO membranes generally exhibited low water permeability, although they showed excellent heat and chlorine resistance. Recently, we introduced hydroxy-containing substituents onto the silicon atoms of PSQs, enhancing the water permeability of PSQ-based RO membranes. Scratch-resistant antifogging coating materials are obtained by introducing amino, ammonium, and hydroxy units onto PSQ silicon atoms. The low durability of the initially studied materials was improved through chemical modification of the PSQ structures.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/tcr.70218","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148560908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Chemical Record of Carbon Quantum Dots: Charting the Course From Mechanistic Insights to Sustainable Technologies 碳量子点的化学记录：绘制从机械洞察到可持续技术的过程。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-08-13 DOI: 10.1002/tcr.70228

Arpit Sharma, Shruti S. Raut, Alok Shukla, Amit Singh, Abha Mishra

{"title":"The Chemical Record of Carbon Quantum Dots: Charting the Course From Mechanistic Insights to Sustainable Technologies","authors":"Arpit Sharma, Shruti S. Raut, Alok Shukla, Amit Singh, Abha Mishra","doi":"10.1002/tcr.70228","DOIUrl":"10.1002/tcr.70228","url":null,"abstract":"Nanotechnology has revolutionized scientific innovation through precise nanoscale manipulation of matter. Among carbon-based nanomaterials, carbon quantum dots (CQDs), carbon nanodots (CNDs), and graphene quantum dots (GQDs) have emerged as next-generation multifunctional nanostructures distinguished by exceptional optical tunability, superior biocompatibility, high aqueous solubility, and excellent chemical stability. These properties enable diverse biomedical applications, including bioimaging, targeted drug and gene delivery, biosensing, and photothermal therapy. Beyond biomedicine, CNDs demonstrate significant potential in optoelectronics and analytical applications as essential components in solar cells, light-emitting diodes (LEDs), and perovskite devices while enabling sensitive detection of heavy metals, hazardous chemicals, and biomolecules. Their intrinsic catalytic activity supports critical environmental and industrial processes such as CO2 reduction, water splitting, and pollutant degradation. Unlike conventional semiconductor QDs containing toxic metals, carbon-based QDs offer a nontoxic, sustainable, and cost-effective alternative with comparable or superior optical and electronic functionalities. This review critically examines synthesis strategies including top-down, bottom-up, and green approaches structural characteristics, photophysical mechanisms, and multifunctional applications. Current challenges, emerging trends, and future directions are outlined, highlighting the promise of carbon-based QDs as sustainable nanoplatforms for advanced biomedical, environmental, and energy technologies.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148758442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanomaterial-Decorated Biomass-Derived Carbon for Electrochemical Sensing: Design Principles, Interfacial Mechanisms, and Practical Applications 纳米材料修饰的生物质衍生碳电化学传感：设计原理、界面机制和实际应用。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-07 DOI: 10.1002/tcr.70209

Md. Rakib Khan, Paricha Jebin, Md. Mehedi Hasan, Somnath Khaladkar, Bong-Joong Kim, A. J. Saleh Ahammad

{"title":"Nanomaterial-Decorated Biomass-Derived Carbon for Electrochemical Sensing: Design Principles, Interfacial Mechanisms, and Practical Applications","authors":"Md. Rakib Khan, Paricha Jebin, Md. Mehedi Hasan, Somnath Khaladkar, Bong-Joong Kim, A. J. Saleh Ahammad","doi":"10.1002/tcr.70209","DOIUrl":"10.1002/tcr.70209","url":null,"abstract":"The increasing demand for highly sensitive and reliable electrochemical sensors (ESs) has driven the development of advanced electrode materials with enhanced catalytic activity and structural tunability. Biomass-derived carbon (BDC) has emerged as a promising platform owing to its natural abundance, low cost, hierarchical porosity, and sustainable synthesis routes. However, pristine BDC often suffers from limited electrical conductivity and insufficient active sites, which can restrict electron-transfer kinetics and compromise sensing performance. Integrating functional nanomaterials with BDC frameworks offers an effective strategy to overcome these limitations and significantly improve electrochemical sensing efficiency. This review presents an overview of nanomaterial-decorated BDC systems for electrochemical sensing applications, including hybrid architectures incorporating metal nanoparticles, metal oxides, hydroxides, sulfides, heteroatom-doped structures, and conducting polymers. We discuss how synthesis strategies, structural characteristics, electronic properties, and defect engineering influence key analytical parameters such as sensitivity, selectivity, detection limit, linear response range, stability, and reproducibility. Particular emphasis is placed on interfacial charge-transfer mechanisms between nanomaterials, BDC frameworks, and target analytes. Current challenges including nanoparticle aggregation and active-site blockage are discussed, and emerging design strategies are highlighted to guide the development of scalable and high-performance BDC-based electrochemical sensing platforms.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148403729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Functional-Group-Engineered Cellulose Separators for Aqueous Zinc-Ion Batteries: Structural Design and Interfacial Regulation Mechanisms 用于锌离子电池的官能团工程纤维素分离器：结构设计和界面调节机制。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-29 DOI: 10.1002/tcr.70226

Shuo Liu, Shaohua Luo, Jun Cong, Rui Huang, Shengxue Yan, Jing Guo, Jun Zhang

{"title":"Functional-Group-Engineered Cellulose Separators for Aqueous Zinc-Ion Batteries: Structural Design and Interfacial Regulation Mechanisms","authors":"Shuo Liu, Shaohua Luo, Jun Cong, Rui Huang, Shengxue Yan, Jing Guo, Jun Zhang","doi":"10.1002/tcr.70226","DOIUrl":"10.1002/tcr.70226","url":null,"abstract":"Aqueous zinc-ion batteries have broad application prospects in large-scale energy storage owing to their high safety, low cost, and environmental compatibility. However, Zn metal anodes still suffer from dendrite growth, hydrogen evolution, corrosion, and interfacial side reactions, which severely limit cycling stability. As a key component connecting the electrolyte and electrode interfaces, the separator has gradually evolved from a conventional physical barrier into a functional layer for regulating Zn2+ transport, water state, and interfacial reactions. Cellulose separators have attracted extensive attention in aqueous zinc-ion batteries because of their abundant resources, renewability, good hydrophilicity, tunable pore structure, and facile chemical modification. This review focuses on functional-group-engineered cellulose separators, highlighting the structural features, advantages, and potential limitations of hydroxyl-rich, carboxylated, sulfonated, and amino-functionalized cellulose separators. The interfacial regulation mechanisms involving Zn2+ coordination and flux homogenization, anion exclusion and selective transport, water-activity regulation, and side-reaction suppression are further discussed. Finally, future directions, including precise functional-group design, fast ion-channel construction, green scalable fabrication, and standardized device-level evaluation, are proposed to provide guidance for the design of highly stable separators for aqueous zinc-ion batteries.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148599743","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Single Atom Catalysis for Furfural Conversion: Recent Advances, Challenges, and Future Perspectives 糠醛转化的单原子催化：最新进展、挑战和未来展望。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-08-12 DOI: 10.1002/tcr.70224

Gargi Dey, Krishnan Ravi, Jacky H. Advani

{"title":"Single Atom Catalysis for Furfural Conversion: Recent Advances, Challenges, and Future Perspectives","authors":"Gargi Dey, Krishnan Ravi, Jacky H. Advani","doi":"10.1002/tcr.70224","DOIUrl":"10.1002/tcr.70224","url":null,"abstract":"Growing global energy demands and the continuous depletion of fossil fuel reserves have intensified interest in renewable alternatives, with biomass emerging as a promising carbon-neutral resource. Furfural (FF), a pivotal platform molecule from lignocellulosic biomass, enables the production of diverse value-added chemicals and fuels. Simultaneously, single-atom catalysts (SACs) have attracted major attention in FF valorization due to their isolated active sites, unique electronic structures, and near-complete atom utilization, enabling high activity and selectivity in complex reaction networks. This review summarizes recent advances in SAC-mediated FF upgrading. Significant progress has been made in thermochemical hydrogenation, yielding furfuryl alcohol, tetrahydrofurfuryl alcohol, and cyclopentanone derivatives. SACs have also shown strong performance in hydrogenolysis to produce high-value products such as 2-methylfuran, 2-methyltetrahydrofuran, and tetrahydrofuran. Rapid developments in reductive amination have enabled the selective synthesis of pharmaceutical-relevant amines, including piperidine, particularly using noble-metal SACs. Although less explored, the selective oxidation of FF to furoic acid and other oxygenates is also highlighted. Emerging electro- and photocatalytic FF transformations demonstrate opportunities for integrating renewable electricity or solar energy. Key challenges include improving SAC scalability and stability, tuning coordination environments, and enabling efficient coupling with green-energy inputs such as electrolytic hydrogen.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148722064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent Advances in the Synthesis of 1,4-Enynes and Their Applications in Organic Synthesis 1,4-烯类化合物的合成及其在有机合成中的应用

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-06 DOI: 10.1002/tcr.70213

Han Cheng, Yakun Li, Heping Li, Linlin Shi, Er-Qing Li, Xin-Qi Hao

{"title":"Recent Advances in the Synthesis of 1,4-Enynes and Their Applications in Organic Synthesis","authors":"Han Cheng, Yakun Li, Heping Li, Linlin Shi, Er-Qing Li, Xin-Qi Hao","doi":"10.1002/tcr.70213","DOIUrl":"10.1002/tcr.70213","url":null,"abstract":"The chemistry of 1,n-enynes, especially 1,4-enynes, represents a privileged scaffold in organic synthesis, constituting both the core structural units of numerous natural products and bioactive molecules and serving as a versatile substrate for diverse transition metal-catalyzed cyclization transformations. Over the past few decades, the synthesis of 1,4-enynes and their application in constructing fused and spirocyclic frameworks have attracted considerable research attention. These synthetic methods offer great promise for the assembly of diverse complex molecules, including pharmaceuticals, natural products, agrochemicals, and functional materials. In this review, recent advances in the synthesis of 1,4-enynes and their chemical transformations with diverse coupling reagents are summarized. Meanwhile, mechanistic studies, supported by experimental investigations, are discussed to illuminate the synergistic interactions governing bond formation. The practical utility of these methodologies is further demonstrated through their application in the synthesis of complex natural products and pharmaceutical intermediates, highlighting their potential for scalable and sustainable chemical manufacturing.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemical Synthesis of Calcium Hydroxide for Low-Carbon Cement Production: A Mini Review 电化学合成氢氧化钙制备低碳水泥的研究进展。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-13 DOI: 10.1002/tcr.70215

Yuzhuo Luo, Guo-Ming Weng

{"title":"Electrochemical Synthesis of Calcium Hydroxide for Low-Carbon Cement Production: A Mini Review","authors":"Yuzhuo Luo, Guo-Ming Weng","doi":"10.1002/tcr.70215","DOIUrl":"10.1002/tcr.70215","url":null,"abstract":"The cement industry is responsible for approximately 8% of global anthropogenic CO2 emissions, largely due to the high-temperature calcination of limestone during clinker production. Electrochemical synthesis of calcium hydroxide (Ca(OH)2) has recently emerged as a promising low-carbon alternative that enables limestone decarbonation under near-ambient conditions. This mini review summarizes most recent progress in electrochemical Ca(OH)2 production for low-carbon cement manufacturing. We first outline the foundational electrochemical principles enabling pH-gradient-driven CaCO3 dissolution and Ca(OH)2 precipitation. We then review major technological advances in reactor architecture, electrode and reaction engineering, membrane design, and feedstock diversification, highlighting strategies that significantly reduce cell voltage, mitigate membrane fouling, and enable continuous operation. Representative electrochemical systems and process configurations are systematically compared. Key technical barriers, including Ca(OH)2 production efficiency, membrane stability, energy consumption, and feedstock impurity tolerance, are also analyzed, together with future research priorities such as advanced membrane materials, integrated process design, and AI-assisted optimization. Continued innovation in electrochemical reactor engineering and system integration could enable scalable low-carbon cement production and contribute significantly to industrial decarbonization.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148435381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visible-Light-Induced Decarboxylative Cross-Coupling Reactions: Transition-Metal and Metal-Free Approaches 可见光诱导脱羧交叉偶联反应：过渡金属和无金属方法。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-28 DOI: 10.1002/tcr.70222

Bhaskarjyoti Borah, Sushmita Banerjee, Alexander Efimov, Bharat Kumar Allam

{"title":"Visible-Light-Induced Decarboxylative Cross-Coupling Reactions: Transition-Metal and Metal-Free Approaches","authors":"Bhaskarjyoti Borah, Sushmita Banerjee, Alexander Efimov, Bharat Kumar Allam","doi":"10.1002/tcr.70222","DOIUrl":"10.1002/tcr.70222","url":null,"abstract":"Photocatalysis has emerged as a powerful and sustainable platform for modern organic synthesis, enabling efficient bond-forming reactions under mild visible-light irradiation. Transition-metal complexes play a crucial role in these systems by facilitating electron-transfer and energy-transfer (EnT) processes, thereby enhancing reaction efficiency and selectivity. Among the numerous transformations accessible through photocatalysis, decarboxylative cross-coupling reactions have emerged as a versatile and efficient tool for the construction of carbon–carbon and carbon–heteroatom bonds, utilizing abundant and stable carboxylic acids as readily available coupling partners. In this review, we critically examined recent advances in visible-light-induced decarboxylative cross-coupling reactions from a coordination-chemistry perspective. Key classes of photocatalysts, including ruthenium-, iridium-, copper-, and nickel-based complexes, are discussed alongside cooperative dual-catalytic systems, metallaphotoredox strategies, and metal-free approaches. Emphasis is placed on the mechanistic pathways governing these transformations, including single-electron transfer, ligand-to-metal charge transfer, and EnT processes. Furthermore, current challenges and emerging opportunities in catalyst design, sustainability, efficiency, and reaction scalability are highlighted, underscoring the central role of coordination chemistry in advancing environmentally benign, energy-efficient catalytic methodologies.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148599727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Surface Mounted Metal–Organic Frameworks for Advanced Sensing: Construction Strategies, Recent Applications, and Emerging Opportunities With Artificial Intelligence 用于高级传感的表面安装金属有机框架：构建策略、最新应用和人工智能的新机遇。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-06 DOI: 10.1002/tcr.70210

Hongxia Mo, Qin Zhou, Junjie Zhang, Dongping Zhan, Jinliang Zhuang

{"title":"Surface Mounted Metal–Organic Frameworks for Advanced Sensing: Construction Strategies, Recent Applications, and Emerging Opportunities With Artificial Intelligence","authors":"Hongxia Mo, Qin Zhou, Junjie Zhang, Dongping Zhan, Jinliang Zhuang","doi":"10.1002/tcr.70210","DOIUrl":"10.1002/tcr.70210","url":null,"abstract":"Sensors play a vital role in modern production and daily life, where high sensitivity, selectivity, and device integration are increasingly required. Metal–organic frameworks (MOFs) have emerged as highly promising materials for sensing applications owing to their high porosity, structural diversity, tunable pore architectures, and tailorable host–guest interactions. However, the practical deployment of MOF powders in sensing devices is often limited by poor processability, random particle packing, and insufficient compatibility with device fabrication. In contrast, surface-mounted metal–organic frameworks (SURMOFs), as highly ordered MOF thin films grown directly on substrates, offer unique advantages for constructing advanced sensing platforms, including controlled orientation, tunable thickness, patterned growth, and excellent compatibility with device integration. In this review, we summarize recent progress in SURMOF-based advanced sensing applications, with emphasis on their fabrication strategies and representative applications in various types of sensors. Particular attention is given to the emerging role of artificial intelligence in SURMOFs synthesis optimization and sensing data processing. Finally, the current challenges and future perspectives of SURMOF-based sensing technologies are discussed.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in the Synthesis of Heterocyclic N-Oxide via Inter- and Intramolecular Cyclization Reactions 分子间和分子内环化反应合成杂环n -氧化物的研究进展。

IF 8.9 2区化学

Chemical record Pub Date : 2026-10-15 Epub Date: 2026-07-01 DOI: 10.1002/tcr.70204

Shubhi Singhal, Shivani Singh, Gaurav Singh, Km. Dali Shukla, Pitambar Patel

{"title":"Advancements in the Synthesis of Heterocyclic N-Oxide via Inter- and Intramolecular Cyclization Reactions","authors":"Shubhi Singhal, Shivani Singh, Gaurav Singh, Km. Dali Shukla, Pitambar Patel","doi":"10.1002/tcr.70204","DOIUrl":"10.1002/tcr.70204","url":null,"abstract":"Heterocyclic N-oxides have become indispensable scaffolds in energetic chemistry, pharmaceuticals, and synthetic organic chemistry. This core scaffold is also present in numerous therapeutic agents, with activities ranging from antimycobacterial and anthelmintic to anti-inflammatory, antioxidant, and anticancer. Over the years, tremendous effort has been devoted to developing efficient synthetic methods starting from simple precursors. Both intermolecular and intramolecular strategies have been widely explored for the construction of cyclic N-oxide derivatives. This review briefly discusses synthetic approaches to the construction of aromatic and aliphatic heterocyclic N-oxides and their derivatives via cyclization reactions from 2011 to 2025. Various synthetic approaches, including inter- and intramolecular cyclization strategies, have been discussed, along with their scope, mechanisms, and limitations. This review not only provides updates on synthetic methods for heterocyclic N-oxide derivatives but also draws the attention of researchers from diverse research fields.","PeriodicalId":10046,"journal":{"name":"Chemical record","volume":"26 10","pages":""},"PeriodicalIF":8.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0