Boletín Médico Del Hospital Infantil de México (English Edition)最新文献

{"title":"Pontine glioma. Pediatric gliomas and the new World Health Organization classification of tumors of the central nervous system","authors":"Fernando Chico-Ponce de León , Mario Perezpeña-Diazconti","doi":"10.1016/j.bmhime.2017.11.018","DOIUrl":"10.1016/j.bmhime.2017.11.018","url":null,"abstract":"","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 2","pages":"Pages 147-153"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.018","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49559079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical-epidemiological study in children with cleft lip palate in a secondary-level hospital","authors":"Alicia Pons-Bonals ,&nbsp;Leticia Pons-Bonals ,&nbsp;Sandra Margarita Hidalgo-Martínez ,&nbsp;Carlos Francisco Sosa-Ferreyra","doi":"10.1016/j.bmhime.2017.11.019","DOIUrl":"https://doi.org/10.1016/j.bmhime.2017.11.019","url":null,"abstract":"<div><h3>Background</h3><p>One of the most common congenital disorders that affect the face structures is the cleft lip palate (CLP). The aim of this study was to obtain the clinical-epidemiological profile of CLP patients from Hospital de Especialidades del Niño y la Mujer (HENM) Dr. Felipe Nuñez Lara, at Queretaro, Mexico, from 2011 to 2014. To provide interdisciplinary treatments for CLP patients based on the information from the pediatric records registered in that period.</p></div><div><h3>Methods</h3><p>Retrospective, cross-sectional, observational study using univariate analysis frequencies for qualitative variables; central statistical and dispersion for quantitative variables and clinical profile. One hundred records were reviewed, from which 15 were excluded for being syndromic cases. Epidemiological, clinical, and socio-demographic variables were studied.</p></div><div><h3>Results</h3><p>The epidemiological profile (variables associated with pregnancy, patient's health at birth, nutritional and psychomotor development, family medical records, and socioeconomic factors) and the clinical profile (disease classified by sex, structure, and affected side, surgeries classified and order in which they took place) of the treated population are presented.</p></div><div><h3>Conclusions</h3><p>The results showed the need to standardize data registration on medical records for improved monitoring and treatment of patients and emphasize actions to maintain a low incidence of CLP in Queretaro.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 2","pages":"Pages 107-121"},"PeriodicalIF":0.0,"publicationDate":"2017-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.019","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"137289015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Telangiectatic osteosarcoma in an infant","authors":"María de los Ángeles Cepeda,&nbsp;Ana Julia Sosa,&nbsp;Glenda Mora","doi":"10.1016/j.bmhime.2017.11.011","DOIUrl":"10.1016/j.bmhime.2017.11.011","url":null,"abstract":"<div><h3>Background</h3><p>Osteosarcoma is one of the most common types of cancer in school age and adolescence being the most common malignant bone tumor in this age group. Osteosarcoma is frequently found in long bones of the extremities. There are very few cases described in children under five years of age. Moreover, according to our revision none in infants. The telangiectatic variant is uncommon, and there are no reports before preschool age.</p></div><div><h3>Case report</h3><p>A 10-month-old female infant that presented a lithic tumor of the ninth right rib, which was classified after resection as a telangiectatic osteosarcoma, is presented.</p></div><div><h3>Conclusions</h3><p>Telangiectatic osteosarcoma in the pediatric age is very uncommon. To date, the patient presented a good response to treatment, although the prognosis and survival of this condition are unknown.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 60-64"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54312039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tuberculosis: the tip of the iceberg","authors":"María Fernanda Castilla-Peón","doi":"10.1016/j.bmhime.2017.11.012","DOIUrl":"https://doi.org/10.1016/j.bmhime.2017.11.012","url":null,"abstract":"","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 3-4"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.012","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136554758","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acute lymphoblastic leukemia: a genomic perspective","authors":"Silvia Jiménez-Morales ,&nbsp;Alfredo Hidalgo-Miranda ,&nbsp;Julián Ramírez-Bello","doi":"10.1016/j.bmhime.2017.11.013","DOIUrl":"10.1016/j.bmhime.2017.11.013","url":null,"abstract":"<div><p>In parallel to the human genome sequencing project, several technological platforms have been developed that let us gain insight into the human genome structure, as well as evaluate their usefulness in the clinical approach of patients. Thus, in acute lymphoblastic leukemia (ALL), the most common pediatric malignancy, genomic tools promise to be useful for detecting patients at high risk of relapse, either at diagnosis or during treatment (minimal residual disease), and they also increase the possibility to identify cases at risk of adverse reactions to chemotherapy. Therefore, the physician could offer patient-tailored therapeutic schemes. A clear example of the useful genomic tools is the identification of single nucleotide polymorphisms (SNPs) in the thiomethyl-purine transferase (<em>TPMT</em>) gene, where the presence of two null alleles (homozygous or compound heterozygous) indicates the need to reduce the dose of mercaptopurine by up to 90% to avoid toxic effects which could lead to the death of the patient.</p><p>In this review, we provide an overview of the genomic perspective of ALL, describing some strategies that contribute to the identification of biomarkers with potential clinical application.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 13-26"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54312217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systematic review of the current status of programs and general knowledge of diagnosis and management of retinoblastoma","authors":"Marco A. Ramírez-Ortiz ,&nbsp;Van C. Lansingh ,&nbsp;Kristen A. Eckert ,&nbsp;Barrett G. Haik ,&nbsp;Blanca X. Phillips ,&nbsp;Vanessa Bosch-Canto ,&nbsp;Graciela González-Pérez ,&nbsp;Astrid Villavicencio-Torres ,&nbsp;Alejandra Etulain-González","doi":"10.1016/j.bmhime.2017.12.001","DOIUrl":"https://doi.org/10.1016/j.bmhime.2017.12.001","url":null,"abstract":"<div><h3>Background</h3><p>This systematic review aims to report the current knowledge of retinoblastoma (Rb) and its implications in Mexico. We analyzed clinical and demographic data of patients with Rb at select hospitals with Rb programs or that treat and refer patients with Rb, and identified the gaps in practice. We propose solutions to improve diagnosis, provide adequate treatment, and improve patient uptake.</p></div><div><h3>Methods</h3><p>A general review was conducted on PubMed of peer-reviewed literature on Rb in Mexico. Ophthalmology Department Heads or Directors of Rb programs at seven hospitals in Mexico were contacted for data available on their patients with Rb.</p></div><div><h3>Results</h3><p>Five hospitals provided clinical data on 777 patients with Rb in a period spanning 2000-2015. Of the 122 patients with treatment, 83.4% underwent enucleation. From 33 to 45.3% of Rb tumors in Mexico reach an advanced intraocular stage of development. Knowledge of the disease is limited, despite the fact that the Mexican Retinoblastoma Group has elaborated Rb treatment guidelines and is developing a national Rb registry. Especially in the Southern states, prevalence and outcomes are comparable to African and Asian countries, and only few patients are referred to national treatment centers. Only three institutions have comprehensive Rb programs.</p></div><div><h3>Conclusions</h3><p>There is an immediate need in Mexico to expand primary care providers’ knowledge of Rb and to expand and upgrade current Rb programs to meet the needs of the population adequately. Diagnosis and care of Rb patients in Mexico can also be improved by the establishment of a national Rb registry and a national early detection program, and by increased use of the national treatment protocol.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 41-54"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.12.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136554760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous closure of ductus arteriosus through an arteriovenous loop in a patient with scimitar syndrome","authors":"Luis Alexis Arévalo Salas,&nbsp;Liborio Solano Fiesco,&nbsp;Jorge Luis Villatoro Fernández","doi":"10.1016/j.bmhime.2017.11.014","DOIUrl":"10.1016/j.bmhime.2017.11.014","url":null,"abstract":"<div><h3>Background</h3><p>Scimitar syndrome consists in a rare malformation characterized by a partial abnormal connection in one or both right pulmonary veins to the inferior vena cava, right lung hypoplasia, and systemic circulation from the descending aorta. Scimitar syndrome is occasionally associated with other congenital malformations, such as patent ductus arteriosus (PDA).</p></div><div><h3>Case report</h3><p>We report a 4-year-old patient with an “adult” variety of scimitar syndrome associated with symptomatic PDA, which was successfully occluded using a retrograde guidewire-established femoral arteriovenous loop with an Amplatzer® PDA occluder, without complications.</p></div><div><h3>Conclusions</h3><p>Scimitar syndrome is complex and requires a complete hemodynamic study for the determination of the appropriate treatment. Pulmonary arterial hypertension is a factor associated with poor prognosis.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 55-59"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54312239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Origins of institutional Pediatrics: Maternity and Childhood Hospital of Mexico City in the nineteenth century","authors":"Manuel Antonio Baeza Bacab","doi":"10.1016/j.bmhime.2017.11.015","DOIUrl":"10.1016/j.bmhime.2017.11.015","url":null,"abstract":"<div><p>In June of 1866, the Empress Carlota founded the Maternity House in the Department of Secret Births at the Hospice of the Poor. Upon the reinstatement of a republican government, Dr. Ramon Pacheco was appointed as director of the Maternity House. Shortly after, in February of 1868, Dr. Luis Fernandez Gallardo established a pavilion for sick children in the Hospital of San Andres. After realizing this pavilion did not have the adequate conditions to operate properly, and in the need of a children's hospital in Mexico City, Dr. Pacheco merged both institutions on April 2, 1869—with the help of Ms. Luciana Arrazola—and founded the Maternity and Childhood Hospital, the first institution for the care of ill children in the independent Mexico. Ever since it was founded, Dr. Eduardo Liceaga was in charge of the children's health. Later, with the help of the presidents Juarez, Lerdo de Tejada, and Díaz, he was able to consolidate the hospital in academic and health services aspects. This noble institution closed its doors on February 5, 1905, upon its incorporation to the General Hospital of Mexico, after 36 years of working for the welfare of Mexican children.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 70-78"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2017.11.015","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54312308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ages and Stages Questionnaire: a global screening scale","authors":"Ajay Singh ,&nbsp;Chia Jung Yeh ,&nbsp;Sheresa Boone Blanchard","doi":"10.1016/j.bmhime.2016.07.001","DOIUrl":"https://doi.org/10.1016/j.bmhime.2016.07.001","url":null,"abstract":"<div><p>With standardized screening tools, research studies have shown that developmental disabilities can be detected reliably and with validity in children as young as 4 months of age by using the instruments such as the Ages and Stages Questionnaire.</p><p>In this review, we will focus on one tool, the Ages and Stages Questionnaire, to illustrate the usefulness of developmental screening across the globe.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 5-12"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2016.07.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136554726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary tract infection caused by Enterobacteriaceae and its relationship with vesicoureteral reflux","authors":"Manuel Díaz Álvarez ,&nbsp;Bárbara Acosta Batista ,&nbsp;Rodolfo Pérez Córdova ,&nbsp;Ernesto Hernández Robledo","doi":"10.1016/j.bmhime.2016.10.001","DOIUrl":"10.1016/j.bmhime.2016.10.001","url":null,"abstract":"<div><h3>Background</h3><p>The first urinary tract infection can be a marker of a urinary tract anomaly, mainly vesicoureteral reflux. The aim of this work was to determine the association between isolated <em>Enterobacteriaceae</em> with the presence and grade of vesicoureteral reflux in neonatal patients at their first urinary tract infection.</p></div><div><h3>Methods</h3><p>A retrospective, observational and analytic study of newborns, who were admitted to the Neonatal Department, of the University Pediatric Hospital Juan Manuel Márquez, in Havana, Cuba, from 1992 to 2013, was conducted. The causal microorganism of urinary tract infection was from the <em>Enterobacteriaceae</em> family. They were evaluated by radio imaging. The association between the presence and grade of vesicoureteral reflux with the causal microorganism of the urinary tract infection was analyzed.</p></div><div><h3>Results</h3><p>Newborn infants with urinary tract infection (450) were studied. Bacterial isolations in the urine cultures corresponded to <em>E. coli</em> in 316 cases (70.2%). The prevalence of vesicoureteral reflux was 18.2%. The presence of bacteria corresponding to the <em>Enterobacteriaceae</em> family (other than <em>E. coli</em>) had a significant risk association with vesicoureteral reflux (OR: 2.02; <em>p</em> &lt; 0.01) and vesicoureteral reflux classification (for higher grades, <em>p</em> &lt; 0.01).</p></div><div><h3>Conclusions</h3><p><em>E. coli</em> is the most common causal microorganism in neonatal urinary tract infection. However, an association between the isolation of a microorganism of the <em>Enterobacteriaceae</em> family different to <em>E. coli</em> with the presence of vesicoureteral reflux and mainly with higher grades of vesicoureteral reflux exists.</p></div>","PeriodicalId":100195,"journal":{"name":"Boletín Médico Del Hospital Infantil de México (English Edition)","volume":"74 1","pages":"Pages 34-40"},"PeriodicalIF":0.0,"publicationDate":"2017-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.bmhime.2016.10.001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"54311137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}