Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects最新文献_第7页

Effects of thioacetamide on labeling of ribonucleic acid of isolated nucleoli in vitro 硫代乙酰胺对离体核仁核糖核酸标记的影响

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90246-4

Jose G. Villalobos Jr. , William J. Steele, Harris Busch

引用次数: 26

Effect of actinomycin and insulin on the metabolism of isolated rat diaphragm 放线菌素和胰岛素对离体大鼠膈肌代谢的影响

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90248-8

Ira G. Wool, Arthur N. Moyer

引用次数: 42

Phosphodiesterase specific for denaturated DNA 磷酸二酯酶专为变性DNA

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90268-3

I.I. Nikolskaya, N.M. Shalina , T.I. Tikhonenko

引用次数: 5

On the mode of action by which the carcinogen dimethylnitrosamine inhibits protein synthesis in the liver 致癌物质二甲基亚硝胺抑制肝脏蛋白质合成的作用方式

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90271-3

I.J. Mizrahi, P. Emmelot

引用次数: 33

Metabolic studies on the sugars of nucleic acids III. 14C-labelling of ribose and deoxyribose in rat tissues in vivo 核酸糖的代谢研究III。大鼠体内组织中核糖和脱氧核糖的14c标记

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90241-5

S. Itzhaki, Elizabeth D. Whittle

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引用次数: 2

Studies on the nucleotide arrangement in deoxyribonucleic acids VIII. A comparison of procedures for the determination of the frequency of pyrimidine nucleotide runs 脱氧核糖核酸中核苷酸排列的研究。嘧啶核苷酸运行频率测定方法的比较

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90250-6

Herman S. Shapiro, Erwin Chargaff

引用次数: 54

Biosynthesis of 3-deoxyribosylxanthine using thymidine phosphorylase 胸苷磷酸化酶生物合成3-脱氧核糖基黄嘌呤

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90257-9

M. Zimmerman , D. Hatfield

引用次数: 7

Retention of transforming activity on filtration of DNA solutions DNA溶液过滤时转化活性的保留

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90265-8

Alvin I. Krasna

引用次数: 3

Cortisol-induced increase of tyrosine-α-ketoglutarate transaminase in the isolated perfused rat liver and its relation to ribonucleic acid synthesis 皮质醇诱导离体灌注大鼠肝脏酪氨酸-α-酮戊二酸转氨酶升高及其与核糖核酸合成的关系

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90247-6

Ottavio Barnabei , Fabio Sereni

{"title":"Cortisol-induced increase of tyrosine-α-ketoglutarate transaminase in the isolated perfused rat liver and its relation to ribonucleic acid synthesis","authors":"Ottavio Barnabei , Fabio Sereni","doi":"10.1016/0926-6550(64)90247-6","DOIUrl":"10.1016/0926-6550(64)90247-6","url":null,"abstract":"<div>It was shown that cortisol increases the level of tyrosine-α-ketoglutarate transaminase (l-tyrosine: 2-oxoglutarate aminotransferase, EC 2.6.1.5) of the isolated rat liver, when perfused with diluted rat blood containing an amino acid mixture; a more striking increase was obtained in the presence of a supplementary amount of tyrosine. This enhancement of activity was blocked by inhibitors both of protein synthesis (chloramphenicol, puromycin, ethionine) and of ribonucleic acid synthesis (actinomycin D and mitomycin C).Adding [6-14C]orotate to the perfusing blood, caused a rapid incorporation of radioactivity into nuclear ribonucleic acid to take place; cytoplasmic ribonucleic acid was poorly labelled after 30 min, but its radioactivity rose thereafter. Cortisol stimulated the labelling of both the nuclear and the cytoplasmic ribonucleic acid; moreover it induced the increase of tyrosine transaminase after a lag of about 30 min. In both cases, the effect of the hormone was prevented by actinomycin D, or by mitomycin C.It was finally found that livers perfused with cortisol have a higher nuclear ribonucleic acid polymerase (nucleosidetriphosphate: RNA nucleotidyltransferase, EC 2.7.7.6) activity than control ones.The facts that the synthesis of nuclear ribonucleic acids precedes the increase of tyrosine transaminase and also that cortisol stimulates ribonucleic acid polymerase strongly suggest that the action of the hormone can be related to an increase in the synthesis of messenger ribonucleic acid molecules for the synthesis of the enzyme.</div>","PeriodicalId":100173,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects","volume":"91 2","pages":"Pages 239-247"},"PeriodicalIF":0.0,"publicationDate":"1964-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6550(64)90247-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23795081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 52

An artifact associated with the use of bentonite clay in the assay for ribonucleic acid polymerization in peanut cotyledons 用膨润土进行花生子叶核糖核酸聚合试验的人工制品

Biochimica et Biophysica Acta (BBA) - Specialized Section on Nucleic Acids and Related Subjects Pub Date : 1964-10-16 DOI: 10.1016/0926-6550(64)90259-2

Amos E. Richmond, Joe H. Cherry

引用次数: 3