Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides最新文献

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The biosynthesis of mucopolysaccharides and glycoproteins in pigment epithelial cells of bovine retina 牛视网膜色素上皮细胞中粘多糖和糖蛋白的生物合成
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90022-9
E.R. Berman
{"title":"The biosynthesis of mucopolysaccharides and glycoproteins in pigment epithelial cells of bovine retina","authors":"E.R. Berman","doi":"10.1016/0926-6526(64)90022-9","DOIUrl":"10.1016/0926-6526(64)90022-9","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 371-373"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90022-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 49
Isolation of a mannose-containing glycopeptide from soybean hemagglutinin 大豆血凝素中含甘露糖糖肽的分离
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90024-2
Halina Lis, Nathan Sharon, Ephraim Katchalski
{"title":"Isolation of a mannose-containing glycopeptide from soybean hemagglutinin","authors":"Halina Lis, Nathan Sharon, Ephraim Katchalski","doi":"10.1016/0926-6526(64)90024-2","DOIUrl":"10.1016/0926-6526(64)90024-2","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 376-378"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90024-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Sulfate incorporation by embryonic chick bone the essentiality of sodium, of potassium, and of protein synthesis 鸡胚骨中硫酸盐的掺入对钠、钾和蛋白质合成的重要性
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90003-5
Lucile Adamson, Sammy Gleason, Constantine Anast
{"title":"Sulfate incorporation by embryonic chick bone the essentiality of sodium, of potassium, and of protein synthesis","authors":"Lucile Adamson,&nbsp;Sammy Gleason,&nbsp;Constantine Anast","doi":"10.1016/0926-6526(64)90003-5","DOIUrl":"10.1016/0926-6526(64)90003-5","url":null,"abstract":"<div><p>Sulfate incorporation by emryonic chick pelvic rudiments requires protein synthesis.</p><p>The incorporation is also dependent on the presence in the incubation medium of both Na<sup>+</sup> and K<sup>+</sup>, and is inhibitable by ouabain.</p><p>In the presence of Na<sup>+</sup> and K<sup>+</sup>, the addition of amino acids to the incubation medium stimulates sulfate incorporation. If other monovalent cations are substituted for either Na<sup>+</sup> or K<sup>+</sup>, sulfate incorporation in the absence of amino acids is decreased and stimulation by addition of amino acids is greatly reduced or eliminated.</p><p>The possibilities that the Na<sup>+</sup> and K<sup>+</sup> requirements are due to the participation by these ions in protein synthesis and in transport into the cell of amino acids, sulfate and glucose are discussed.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 262-271"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90003-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 19
The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrate for lysozyme 浓盐酸水解几丁质,制备低分子量溶菌酶底物
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90001-1
J.A. Rupley
{"title":"The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrate for lysozyme","authors":"J.A. Rupley","doi":"10.1016/0926-6526(64)90001-1","DOIUrl":"10.1016/0926-6526(64)90001-1","url":null,"abstract":"<div><p>The hydrolysis of chitin in solution in strong HCl was studied over a range of acid concentration and temperature. The data suggest that the rate of hydrolysis governed by the structure of the chitin. A simple procedure for the isolation of the oligosaccharides obtained from chitin was developed, for use in the preparation of low-molecular-weight substrates for lysozyme (<em>N</em>-acetylmuramide glycanohydrolase, EC 3.2.1.17). Experiments studying the lysozyme-catalyzed hydrolysis of these oligosaccharides showed a large effect of chain length upon the rate of hydrolysis, and no effect of ionic strength.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 245-255"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90001-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 414
Chemical synthesis of N-acetylhexosamine 6-sulfates 6-硫酸盐n -乙酰己糖胺的化学合成
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90002-3
E. Meezan, A.H. Olavesen, E.A. Davidson
{"title":"Chemical synthesis of N-acetylhexosamine 6-sulfates","authors":"E. Meezan,&nbsp;A.H. Olavesen,&nbsp;E.A. Davidson","doi":"10.1016/0926-6526(64)90002-3","DOIUrl":"10.1016/0926-6526(64)90002-3","url":null,"abstract":"<div><p>The 6-sulfates of <em>N</em>-acetylglucosamine and <em>N</em>-acetylgalactosamine were synthesized using triethylamine-<em>N</em>-sulfonic acids as the sulfating agent. The products of the reaction were purified by fractionation on an anion-exchange column, desalted by means of an ion-retardation resin and converted to the barium salts by passage through the barium form of a cation-exchange resin. Evidence for the homogeneity of the 6-sulfates was provided by chemical analysis, paper chromatography. electrophoresis, colorimetric assay and infrared spectra. Proof for the position of the sulfate group on the primary hydroxyl of the <em>N</em>-acetylhexosamines was provided by periodate consumption studies, the detection of glycolaldehyde sulfate as an end product of periodate oxidation and comparison with a sample of <em>N</em>-acetylglucosamine 6-sulfate synthesized by an unambiguous route. The latter product was prepared via the 6-trityl intermediate as described in the text.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 256-261"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90002-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
Acide sialique dans les larmes humaines 人类眼泪中的唾液酸
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90009-6
J.A Cabezas, J.V Porto, M.D Frois, C Marino, J Arzúa
{"title":"Acide sialique dans les larmes humaines","authors":"J.A Cabezas,&nbsp;J.V Porto,&nbsp;M.D Frois,&nbsp;C Marino,&nbsp;J Arzúa","doi":"10.1016/0926-6526(64)90009-6","DOIUrl":"10.1016/0926-6526(64)90009-6","url":null,"abstract":"<div><p><em>N</em>-Acetylneuraminic acid has been identified in human tears; other accompanying sialic acids have not been found. <em>N</em>-Acetylneuraminic acid has not been found free, but found. A remarkable release is easily produced by hydrolysis with 0.1 N HCl or 0.1 N H<sub>2</sub>SO<sub>4</sub> at 80° and with neuraminidase (sialidase) (<em>N</em>-acetylneuraminate glycohydrolase, EC 3.2.1.18) at pH 5.5 and 37°, after about 45 min.</p><p>Paper electrophoresis shows its main distribution in a fraction of the pherogram with a mobility of −3.8·10<sup>−5</sup> cm<sup>2</sup> sec<sup>−1</sup> V<sup>−1</sup> which would correspond to the α-seroglobulins.</p><p>The mean concentration in tears is determined, as well as that of hexoses and hexosamines, and a discussion is made about its biochemical signification.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 318-325"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90009-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91068623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 27
The use of Sephadex G-25 for the isolation of nucleotide sugar derivatives from Micrococcus lysodeikticus 用Sephadex G-25分离溶改微球菌的核苷酸糖衍生物
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90025-4
Spencer Rosenthal, Nathan Sharon
{"title":"The use of Sephadex G-25 for the isolation of nucleotide sugar derivatives from Micrococcus lysodeikticus","authors":"Spencer Rosenthal,&nbsp;Nathan Sharon","doi":"10.1016/0926-6526(64)90025-4","DOIUrl":"10.1016/0926-6526(64)90025-4","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 378-380"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90025-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 15
Dissociation of M- and N-group mucoproteins in subunits in detergen solutions 洗涤剂溶液中亚基中M-和n -基团黏蛋白的解离
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90012-6
A Morawiecki
{"title":"Dissociation of M- and N-group mucoproteins in subunits in detergen solutions","authors":"A Morawiecki","doi":"10.1016/0926-6526(64)90012-6","DOIUrl":"10.1016/0926-6526(64)90012-6","url":null,"abstract":"<div><p>In alkyl sulfate detergents the M- and N-group antigen mucoproteins having a molecular weight of about 10<sup>6</sup> Daltons dissociate into subunits. Their molecular weight at infinite dilution was determined as 3·10<sup>4</sup> Daltons. At finite mucoprotein concentrations a dynamic association-dissociation equilibrium between the subunits was observed. On dissolving in dimethylformamide-formic acid mixture (9:1 v/v), the M and N mucoprotein macromolecules disintegrated into fragments with a molecular weight of about 9·10<sup>4</sup> Daltons. Removal of the detergent from the dissociated mucoprotein resulted in reaggregation of the subunits, and the material exhibited unchanged serological activity. The observations suggest that in water solutions the subunits are kept in aggressive forms by hydrophobic bonds. This may be caused by asymmetric distribution of hydrophilic residues (sugars, amino sugars, and sialic acid) along the polypeptide backbone of the subunits.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 339-347"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90012-6","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 91
Enzymatic synthesis of uridine diphosphate glucosaminuronic acid 酶法合成尿苷二磷酸葡萄糖氨基醛酸
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90016-3
Jeremiah E. Slivert , Edward F.X. Hughes
{"title":"Enzymatic synthesis of uridine diphosphate glucosaminuronic acid","authors":"Jeremiah E. Slivert ,&nbsp;Edward F.X. Hughes","doi":"10.1016/0926-6526(64)90016-3","DOIUrl":"10.1016/0926-6526(64)90016-3","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 355-357"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90016-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
A biological chemical and physical comparison of heparin from differential mammalian species 不同哺乳动物种类肝素的生物化学和物理比较
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 Epub Date: 2003-02-05 DOI: 10.1016/0926-6526(64)90004-7
Grant H. Barlow, Lyle J. Coen, Milton M. Mozen
{"title":"A biological chemical and physical comparison of heparin from differential mammalian species","authors":"Grant H. Barlow,&nbsp;Lyle J. Coen,&nbsp;Milton M. Mozen","doi":"10.1016/0926-6526(64)90004-7","DOIUrl":"10.1016/0926-6526(64)90004-7","url":null,"abstract":"<div><p>Since improvements in the isolation procedure have resulted in heparin of high biological activity, the question of species difference has been reexamined. We have isolated heparin from dog, beef, hog, sheep and human tissue by selective fractionation with quaternary ammonium compounds. Based on our results we would suggest that heparins isolated from various mammalian species are biologically, chemically and physically similar. The biological variations previously observed may well be a result of different degree of purity in the heparin isolated.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 272-277"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90004-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
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