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Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides最新文献

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An X-ray diffraction study of calcium chondroitin sulfate A 硫酸软骨素钙A的x射线衍射研究
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90014-X
Frederick A. Bettelheim
{"title":"An X-ray diffraction study of calcium chondroitin sulfate A","authors":"Frederick A. Bettelheim","doi":"10.1016/0926-6526(64)90014-X","DOIUrl":"10.1016/0926-6526(64)90014-X","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 350-352"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90014-X","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Acid mucopolysaccharides in rat kidneys 大鼠肾脏中的酸性粘多糖
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90005-9
D. Allalouf , A. Ber , N. Sharon
{"title":"Acid mucopolysaccharides in rat kidneys","authors":"D. Allalouf ,&nbsp;A. Ber ,&nbsp;N. Sharon","doi":"10.1016/0926-6526(64)90005-9","DOIUrl":"10.1016/0926-6526(64)90005-9","url":null,"abstract":"<div><p>An acid mucopolysaccharide preparation was isolated from rat kidneys. Its major amino sugar component was glucosamine, with only minor amounts of galactosamine. It contained sulphate, gave a positive carbazole reaction for uronic acids with a high carbazole: orcinol ratio, and possessed anticoagulant activity. The preparation could be further fractionated with the aid of cetyl pyridinium chloride, and by chromatography on columns of Ecteolal-cellulose and DEAE-Sephadex. From these studies it was concluded that the major component of the mucopolysaccharide preparation was a heparin-like substance, and that hyaluronic acid was present as a minor component. Since mucopolysaccharides containing galactosamine were found only in small quantities, it appears that rat kidneys do not contain significant amounts of chondroitin sulphates.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 278-287"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90005-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
Properties of electroplax protein part III 电火花蛋白的性质第三部分
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90007-2
Eberhard G. Trams, Carl J. Lauter
{"title":"Properties of electroplax protein part III","authors":"Eberhard G. Trams,&nbsp;Carl J. Lauter","doi":"10.1016/0926-6526(64)90007-2","DOIUrl":"10.1016/0926-6526(64)90007-2","url":null,"abstract":"<div><p></p><ul><li><span>1.</span><span><p>1. The isolation and characterization of a protein fraction from the electric organ of <em>Electrophorus electricus</em> is described. The protein was a material of relatively low molecular weight. It was soluble in water, dilute base and dilute acid and had many of the characteristics of mucoproteins.</p></span></li><li><span>2.</span><span><p>2. Analytical studies revealed the presence of galactose, <em>N</em>-acetylgalactosamine, glucuronic acid and of <em>N</em>-acetylneuraminic acid. Evidence is presented which indicated, however, that the carbohydrate constituents did not occur as a single polysaccharide moiety. The protein or polypeptide moiety apparently does not contain any of the aromatic amino acids.</p></span></li><li><span>3.</span><span><p>3. Physical studies of the isolated sialoprotein reveal marked polyanionic characteristics. Dye-binding and dye-displacement studies as measured by fluorescence quenching demonstrated that “receptor-like” function was simulated by this materiall. It was concluded, however, that this particular sialoprotein, in the form isolated, merely showed ion-exchange capabilities and lacked the high degree of specificity postulated for biological receptors.</p></span></li></ul></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 296-304"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90007-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Studies of casein VII. The carbohydrate constitution of glycopeptidic material isolated from enzymic hydrolysates of κ-casein 酪蛋白的研究7。从κ-酪蛋白酶解物中分离的糖肽类物质的碳水化合物构成
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90011-4
F.Y-Y. Huang, G.O. Henneberry, B.E. Baker
{"title":"Studies of casein VII. The carbohydrate constitution of glycopeptidic material isolated from enzymic hydrolysates of κ-casein","authors":"F.Y-Y. Huang,&nbsp;G.O. Henneberry,&nbsp;B.E. Baker","doi":"10.1016/0926-6526(64)90011-4","DOIUrl":"10.1016/0926-6526(64)90011-4","url":null,"abstract":"<div><p>κ-Casein was hydrolyzed with either crystalline papain (EC 3.4.4.10) or Pronase P. The products of hydrolysis were fractionated by means of ion exchange and Sephadex G-25. A carbohydrate-rich macropeptide isolated from the papain digest contained 4–5 times the quantities of hexose, hexosamine and sialic acid that were present in κ-casein. The concentrations of the three saccharides bore approximately the same ratio to each other in κ-casein as they did in the macropeptide fraction. These results suggested that the carbohydrate part of κ-casein may be a prosthetic group containing hexose, hexosamine and sialic acid in the ratio of 1:1:1. The macropeptide fraction isolated from the Pronase-P hydrolyate contained approximately double the quantity of carbohydrate that was present in the macropeptide isolated from the papain digest.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 333-338"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90011-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Isolation of chondroitin from squid skin 鱿鱼皮中软骨素的分离
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90013-8
K. Anno, Y. Kawai, N. Seno
{"title":"Isolation of chondroitin from squid skin","authors":"K. Anno,&nbsp;Y. Kawai,&nbsp;N. Seno","doi":"10.1016/0926-6526(64)90013-8","DOIUrl":"10.1016/0926-6526(64)90013-8","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 348-349"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90013-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 30
Heterogeneity of sialomucopolysaccharides prepared from whole rat brain 大鼠全脑唾液多聚糖的异质性研究
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90017-5
Eric G. Brunngraber, Barbara D. Brown
{"title":"Heterogeneity of sialomucopolysaccharides prepared from whole rat brain","authors":"Eric G. Brunngraber,&nbsp;Barbara D. Brown","doi":"10.1016/0926-6526(64)90017-5","DOIUrl":"10.1016/0926-6526(64)90017-5","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 357-360"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90017-5","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
Correlation of adjuvant activity and chemical structure of mycobacterial wax D fractions: The importance of amino sugars 分枝杆菌蜡D组分的佐剂活性与化学结构的相关性:氨基糖的重要性
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90018-7
Pierre Jollès, Danièle Samour-Migliore, Hermine De Wijs, Edgar Lederer
{"title":"Correlation of adjuvant activity and chemical structure of mycobacterial wax D fractions: The importance of amino sugars","authors":"Pierre Jollès,&nbsp;Danièle Samour-Migliore,&nbsp;Hermine De Wijs,&nbsp;Edgar Lederer","doi":"10.1016/0926-6526(64)90018-7","DOIUrl":"10.1016/0926-6526(64)90018-7","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 361-363"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90018-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 18
Production of a new acidic polysaccharide containing succinic acid by a soil bacterium 土壤细菌生产一种含琥珀酸的新型酸性多糖
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90023-0
Tokuya Harada, Tadashi Yoshimura
{"title":"Production of a new acidic polysaccharide containing succinic acid by a soil bacterium","authors":"Tokuya Harada,&nbsp;Tadashi Yoshimura","doi":"10.1016/0926-6526(64)90023-0","DOIUrl":"10.1016/0926-6526(64)90023-0","url":null,"abstract":"","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 374-376"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90023-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23789293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrate for lysozyme 浓盐酸水解几丁质，制备低分子量溶菌酶底物
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90001-1
J.A. Rupley
{"title":"The hydrolysis of chitin by concentrated hydrochloric acid, and the preparation of low-molecular-weight substrate for lysozyme","authors":"J.A. Rupley","doi":"10.1016/0926-6526(64)90001-1","DOIUrl":"10.1016/0926-6526(64)90001-1","url":null,"abstract":"<div><p>The hydrolysis of chitin in solution in strong HCl was studied over a range of acid concentration and temperature. The data suggest that the rate of hydrolysis governed by the structure of the chitin. A simple procedure for the isolation of the oligosaccharides obtained from chitin was developed, for use in the preparation of low-molecular-weight substrates for lysozyme (<em>N</em>-acetylmuramide glycanohydrolase, EC 3.2.1.17). Experiments studying the lysozyme-catalyzed hydrolysis of these oligosaccharides showed a large effect of chain length upon the rate of hydrolysis, and no effect of ionic strength.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 245-255"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90001-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785822","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 414
Chemical synthesis of N-acetylhexosamine 6-sulfates 6-硫酸盐n -乙酰己糖胺的化学合成
Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides Pub Date : 1964-11-01 DOI: 10.1016/0926-6526(64)90002-3
E. Meezan, A.H. Olavesen, E.A. Davidson
{"title":"Chemical synthesis of N-acetylhexosamine 6-sulfates","authors":"E. Meezan,&nbsp;A.H. Olavesen,&nbsp;E.A. Davidson","doi":"10.1016/0926-6526(64)90002-3","DOIUrl":"10.1016/0926-6526(64)90002-3","url":null,"abstract":"<div><p>The 6-sulfates of <em>N</em>-acetylglucosamine and <em>N</em>-acetylgalactosamine were synthesized using triethylamine-<em>N</em>-sulfonic acids as the sulfating agent. The products of the reaction were purified by fractionation on an anion-exchange column, desalted by means of an ion-retardation resin and converted to the barium salts by passage through the barium form of a cation-exchange resin. Evidence for the homogeneity of the 6-sulfates was provided by chemical analysis, paper chromatography. electrophoresis, colorimetric assay and infrared spectra. Proof for the position of the sulfate group on the primary hydroxyl of the <em>N</em>-acetylhexosamines was provided by periodate consumption studies, the detection of glycolaldehyde sulfate as an end product of periodate oxidation and comparison with a sample of <em>N</em>-acetylglucosamine 6-sulfate synthesized by an unambiguous route. The latter product was prepared via the 6-trityl intermediate as described in the text.</p></div>","PeriodicalId":100172,"journal":{"name":"Biochimica et Biophysica Acta (BBA) - Specialized Section on Mucoproteins and Mucopolysaccharides","volume":"83 3","pages":"Pages 256-261"},"PeriodicalIF":0.0,"publicationDate":"1964-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0926-6526(64)90002-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"23785823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
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