Advanced Sensor Research最新文献

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High-Resolution Printed Ethylene Vinyl Acetate Based Strain Sensor for Impact Sensing 基于乙烯-醋酸乙烯酯的高分辨率印刷型应变传感器用于冲击感应
Advanced Sensor Research Pub Date : 2024-03-11 DOI: 10.1002/adsr.202300189
Pariya Nazari, Johannes Zimmermann, Christian Melzer, Wolfgang Kowalsky, Jasmin Aghassi-Hagmann, Gerardo Hernandez-Sosa, Uli Lemmer
{"title":"High-Resolution Printed Ethylene Vinyl Acetate Based Strain Sensor for Impact Sensing","authors":"Pariya Nazari,&nbsp;Johannes Zimmermann,&nbsp;Christian Melzer,&nbsp;Wolfgang Kowalsky,&nbsp;Jasmin Aghassi-Hagmann,&nbsp;Gerardo Hernandez-Sosa,&nbsp;Uli Lemmer","doi":"10.1002/adsr.202300189","DOIUrl":"10.1002/adsr.202300189","url":null,"abstract":"<p>The strongly growing interest in digitalizing society requires simple and reliable strain-sensing concepts. In this work, a highly sensitive stretchable sensor is presented using a straightforward and scalable printing method. The piezoresistive sensor consists of conductive core–shell microspheres embedded in an elastomer. As the elastomer, ethylene vinyl acetate (EVA) is employed as an efficient and cost-effective alternative compared to polydimethylsiloxane (PDMS). EVA allows for a significantly lower percolation threshold and low hysteresis compared with PDMS. Using 35 µm microspheres, a detection limit of 0.01% is achieved. When using 4 µm microspheres, the sensor shows a detection limit of 0.015% and electromechanical robustness against 1000 cycles of 0–1% strain. The stretchable strain sensor is successfully implemented as an impact sensor and a diaphragm expansion monitoring sensor. Fast (20 ms) and high-resolution response as well as mechanical robustness to strain values greater than the linear working range of the sensor are demonstrated. The results of this research indicate the promising potential of employing conductive microspheres embedded in the EVA matrix for fast and precise strain detection applications.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300189","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cutting-Edge Technology for Early Intervention in Myocardial Infarction: Portable Fingertips-Based Immunobiosensor 用于心肌梗塞早期干预的尖端技术:基于指尖的便携式免疫生物传感器
Advanced Sensor Research Pub Date : 2024-03-10 DOI: 10.1002/adsr.202300204
Zhichao Yu, Di Wu, Yuan Gao, Yunsen Wang, Yongyi Zeng, Dianping Tang, Xiaolong Liu
{"title":"Cutting-Edge Technology for Early Intervention in Myocardial Infarction: Portable Fingertips-Based Immunobiosensor","authors":"Zhichao Yu,&nbsp;Di Wu,&nbsp;Yuan Gao,&nbsp;Yunsen Wang,&nbsp;Yongyi Zeng,&nbsp;Dianping Tang,&nbsp;Xiaolong Liu","doi":"10.1002/adsr.202300204","DOIUrl":"10.1002/adsr.202300204","url":null,"abstract":"<p>Early intervention in acute myocardial infarction can minimize myocardial damage and improve patient survival. Herein, a low-cost device-free portable immunobiosensing platform for flexible monitoring of immediate myocardial infarction is reported. CuS-Pt nanofragments (CuS-Pt NFs) with high photothermal conversion efficiency (≈26.41%) are synthesized by liquid-phase polarity-mediated synthesis. The CuS NFs are loaded in situ with platinum (Pt) nanoreactors using a solvothermal reduction strategy, which is employed to enhance the efficiency of gas production. The resulting CuS-Pt nanocatalysts are encapsulated within liposomes for signal cascade amplification. Specifically, cardiac troponin I (cTn I), a target biomarker in serum, is captured on pre-modified microtiter plates and formed into a classical sandwich model. The thermo-chemically kinetically enhanced CuS-Pt reactor is released through a one-step chemical treatment and transferred to a closed gas generator. Under the excitation of a near-infrared laser emitter, the internal pressure in the gas generator device increases with time and drives the carbon quantum dot solution in the connected hose. The moving distance shows a correlation with the target concentration. This work provides a new implementation for the development of low-cost, efficient pressure immunosensors without the requirement of a readout device.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sensor Technologies for Hydraulic Valve and System Performance Monitoring: Challenges and Perspectives 用于液压阀和系统性能监控的传感器技术:挑战与展望
Advanced Sensor Research Pub Date : 2024-03-10 DOI: 10.1002/adsr.202300130
Jingqi Liu, Chenggang Yuan, Lukas Matias, Chris Bowen, Vimal Dhokia, Min Pan, James Roscow
{"title":"Sensor Technologies for Hydraulic Valve and System Performance Monitoring: Challenges and Perspectives","authors":"Jingqi Liu,&nbsp;Chenggang Yuan,&nbsp;Lukas Matias,&nbsp;Chris Bowen,&nbsp;Vimal Dhokia,&nbsp;Min Pan,&nbsp;James Roscow","doi":"10.1002/adsr.202300130","DOIUrl":"10.1002/adsr.202300130","url":null,"abstract":"<p>Hydraulic fluid power systems are essential for a range of engineering applications such as transportation, heavy industry, and robotics. The scale of the industry is such that hydraulic pumps are estimated to account for 15% of all the energy consumption in the European Union and yet the average efficiency of fluid power systems is only 22%. The digitalization of hydraulic systems offers significant advantages in terms of energy efficiency, performance, reduced maintenance, and automation. However, this requires advances in the integration of smart sensing technologies to provide real-time feedback on the operation and health of hydraulic components. This review details developing trends in hydraulic fluid power research and provides an overview of progress related to the digitalization of these systems and their integration within an Industry 4.0 framework. The fundamentals of relevant sensor technologies and innovative approaches for integrating sensors into hydraulics systems are discussed. Methods to deliver power to the sensors and associated electronics through harvested pressure ripples are also reviewed. An outlook with respect to future directions in this field is given, including an assessment of the potential for exploiting advanced manufacturing technologies, in particular additive manufacturing, to facilitate successful sensor integration into hydraulic fluid power systems.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300130","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140254803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Novel Fluorogenic Probe Reveals Lipid Droplet Dynamics in ME/CFS Fibroblasts 新型荧光探针揭示了 ME/CFS 成纤维细胞中脂滴的动态变化
Advanced Sensor Research Pub Date : 2024-03-10 DOI: 10.1002/adsr.202300178
Siyang Ding, Oana Sanislav, Daniel Missailidis, Claire Yvonne Allan, Tze Cin Owyong, Ming-Yu Wu, Sijie Chen, Paul Robert Fisher, Sarah Jane Annesley, Yuning Hong
{"title":"A Novel Fluorogenic Probe Reveals Lipid Droplet Dynamics in ME/CFS Fibroblasts","authors":"Siyang Ding,&nbsp;Oana Sanislav,&nbsp;Daniel Missailidis,&nbsp;Claire Yvonne Allan,&nbsp;Tze Cin Owyong,&nbsp;Ming-Yu Wu,&nbsp;Sijie Chen,&nbsp;Paul Robert Fisher,&nbsp;Sarah Jane Annesley,&nbsp;Yuning Hong","doi":"10.1002/adsr.202300178","DOIUrl":"10.1002/adsr.202300178","url":null,"abstract":"<p>Lipid droplets (LDs) are dynamic cellular organelles that play an essential role in lipid metabolism and storage. LD dysregulation has been implicated in various diseases. However, investigations into the cellular LD dynamics under disease conditions have been rarely reported, possibly due to the absence of high performing LD imaging agents. Here a novel fluorogenic probe, AM-QTPA, is reported for specific LD imaging. AM-QTPA demonstrates viscosity sensitivity and aggregation-induced emission enhancement characteristics. It is live cell permeable and can specifically light up LDs in cells, with low background noise and superior signals that can be quantified. After validation in cell model with LD accumulation induced by oleic acid treatment, AM-QTPA is applied in a small proof-of-concept number of human fibroblast samples derived from people diagnosed with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), a complex and debilitating disease with unknown cause. The results indicate the presence of larger but fewer LDs in ME/CFS fibroblasts compared to the healthy counterparts, accompanying with frequent LD-mitochondria contacts, suggesting potential upregulation of lipolysis in ME/CFS connective tissue like fibroblasts. Overall, AM-QTPA provides new understanding of the anomalous LD dynamics in disease status, which, potentially, will facilitate in-depth investigation of the pathogenesis of ME/CFS.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300178","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140255133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Resistive Self-Sensing Controllable Fabric-Based Actuator: A Novel Approach to Creating Anisotropy 电阻式自感应可控织物致动器:创造各向异性的新方法
Advanced Sensor Research Pub Date : 2024-03-08 DOI: 10.1002/adsr.202300108
Ayse Feyza Yilmaz, Kadir Ozlem, Fidan Khalilbayli, Mehmet Fatih Celebi, Fatma Kalaoglu, Asli Tuncay Atalay, Gökhan Ince, Ozgur Atalay
{"title":"Resistive Self-Sensing Controllable Fabric-Based Actuator: A Novel Approach to Creating Anisotropy","authors":"Ayse Feyza Yilmaz,&nbsp;Kadir Ozlem,&nbsp;Fidan Khalilbayli,&nbsp;Mehmet Fatih Celebi,&nbsp;Fatma Kalaoglu,&nbsp;Asli Tuncay Atalay,&nbsp;Gökhan Ince,&nbsp;Ozgur Atalay","doi":"10.1002/adsr.202300108","DOIUrl":"10.1002/adsr.202300108","url":null,"abstract":"<p>Designing advanced soft robots with soft sensing capabilities for real-world applications remains challenging due to the intricate integration of actuation and sensor capabilities, which require diverse materials and complex procedures. This paper introduces a fabric-based robotic technology featuring an “all textile-based self-sensing pneumatic actuator” and a low-cost resistive strain sensor created through simple sewing techniques. The novel approach eliminates the need for additional strain-limiting woven fabric, simplifying the manufacturing process. It also enables the development of bioinspired motions such as bending, twisting, and snake-like movements. The electromechanical behaviors of the sensor and bending actuator are tested for their performance under positive air pressure. Through mathematical modeling, the actuator's sensing capacity is estimated accurately, providing precise feedback for pressure and position control. Different closed-loop controller types, including On–Off and Proportional Integral Derivative (PID) control, are evaluated for their effectiveness. Furthermore, the practical application of the sensing actuator is demonstrated by integrating it into a wearable glove, showcasing its enhanced sensing capabilities for finger-like soft wearable robotic applications. This research tackles the challenges associated with designing advanced soft robots with integrated sensing capabilities, offering a promising fabric-based solution that can drive significant advancements in real-world applications.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140257360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Masthead (Adv. Sensor Res. 3/2024) 桅顶(传感器推进决议 3/2024)
Advanced Sensor Research Pub Date : 2024-03-07 DOI: 10.1002/adsr.202470011
{"title":"Masthead (Adv. Sensor Res. 3/2024)","authors":"","doi":"10.1002/adsr.202470011","DOIUrl":"https://doi.org/10.1002/adsr.202470011","url":null,"abstract":"","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202470011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140063761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring (Adv. Sensor Res. 3/2024) 可穿戴传感器的新兴添加剂制造方法:扩大获得个性化健康监测的机会(传感器研究进展 3/2024)
Advanced Sensor Research Pub Date : 2024-03-07 DOI: 10.1002/adsr.202470010
Ziyu Yin, Kaylee M. Clark, Tyler R. Ray
{"title":"Emerging Additive Manufacturing Methods for Wearable Sensors: Opportunities to Expand Access to Personalized Health Monitoring (Adv. Sensor Res. 3/2024)","authors":"Ziyu Yin,&nbsp;Kaylee M. Clark,&nbsp;Tyler R. Ray","doi":"10.1002/adsr.202470010","DOIUrl":"https://doi.org/10.1002/adsr.202470010","url":null,"abstract":"<p><b>3D-Printed Wearable Sensors</b></p><p>In article 2300137, Tyler R. Ray and co-workers review the latest advancements in the additive manufacture of wearable devices for physiological health monitoring to highlight the transformative potential of 3D printing to address some of the persistent disparities in healthcare that disproportionately affect underserved and vulnerable populations by expanding access to state-of-the-art sensing technology.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202470010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140063760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication and Characterization of Electrically Conductive 3D Printable TPU/MWCNT Filaments for Strain Sensing in Large Deformation Conditions 用于大变形条件下应变传感的导电三维打印热塑性聚氨酯/MWCNT 纤维的制作与表征
Advanced Sensor Research Pub Date : 2024-03-04 DOI: 10.1002/adsr.202300198
Behrad Koohbor, Wei Xue, Kazi Z. Uddin, George Youssef, Daniel Nerbetski, Bradley Steiger, Joseph Kenney, Dana Yarem
{"title":"Fabrication and Characterization of Electrically Conductive 3D Printable TPU/MWCNT Filaments for Strain Sensing in Large Deformation Conditions","authors":"Behrad Koohbor,&nbsp;Wei Xue,&nbsp;Kazi Z. Uddin,&nbsp;George Youssef,&nbsp;Daniel Nerbetski,&nbsp;Bradley Steiger,&nbsp;Joseph Kenney,&nbsp;Dana Yarem","doi":"10.1002/adsr.202300198","DOIUrl":"10.1002/adsr.202300198","url":null,"abstract":"<p>This study investigates the development of thermoplastic polyurethane (TPU) filaments incorporating multi-walled carbon nanotubes (MWCNT) to enhance strain-sensing capabilities. Various MWCNT reinforcement ratios are used to produce customized feedstock for fused filament fabrication (FFF) 3D printing. Mechanical properties and the piezoresistive response of samples printed with these multifunctional filaments are concurrently evaluated. Surface morphology and microstructural observations reveal that higher MWCNT weight percentages increase filament surface roughness and rigidity. The microstructural modifications directly influence the tensile strength and strain energy of the printed samples. The study identifies an apparent percolation threshold within the 10–12 wt.% MWCNT range, indicating the formation of a conductive network. At this threshold, higher gauge factors are achieved at lower strains. A newly introduced Electro-Mechanical Sensitivity Ratio (ESR) parameter enables the classification of composite behaviors into two distinct zones, offering the ability to tailor self-sensing structures with on-demand properties. Finally, flexible structures with proven application in soft robotics and shape morphing are fabricated and tested at different loading conditions to demonstrate the potential applicability of the custom filaments produced. The results highlight a pronounced piezoresistive response and superior load-bearing performance in the examined structures.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300198","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140266228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Performance Comparison Between Organic Electrochemical Transistor and Electrode Configurations for Enzymatic Sensing 用于酶传感的有机电化学晶体管和电极配置的性能比较
Advanced Sensor Research Pub Date : 2024-03-03 DOI: 10.1002/adsr.202300188
Abdulelah Saleh, Shofarul Wustoni, Luca Salvigni, Anil Koklu, Victor Druet, Jokubas Surgailis, Prem D. Nayak, Sahika Inal
{"title":"A Performance Comparison Between Organic Electrochemical Transistor and Electrode Configurations for Enzymatic Sensing","authors":"Abdulelah Saleh,&nbsp;Shofarul Wustoni,&nbsp;Luca Salvigni,&nbsp;Anil Koklu,&nbsp;Victor Druet,&nbsp;Jokubas Surgailis,&nbsp;Prem D. Nayak,&nbsp;Sahika Inal","doi":"10.1002/adsr.202300188","DOIUrl":"10.1002/adsr.202300188","url":null,"abstract":"<p>Organic electrochemical transistors (OECTs) excel at biosensing due to their high amplification factor, which allows for detecting low analyte concentrations and picking up weak physiological signals. One prominent use of OECT is in enzymatic metabolite sensing, with the OECT claimed to have a superior low limit of detection and enhanced sensitivity compared to conventional two or three electrode-based setups. However, there has yet to be a direct comparative study on the performance metrics of these sensor configurations under unified conditions. Here, the glucose sensing performance of an enzyme-immobilized electrode is systematically examined in two types of devices that have the same geometrical relations: the first one is a traditional 2- or 3-electrode configuration where the sensing electrode is the working electrode, and in the second one, the enzymatic electrode serves as the gate electrode of an OECT. While benchmarking the performance of OECT technology for enzyme-based metabolite sensing, this study provides insights into the operation mechanism of OECT-based enzymatic sensors. These results can help to design more efficient OECT-based circuits to transduce biological events that involve redox reactions.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202300188","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140080947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An Efficient Low-Cost Device for Sampling Exhaled Breath Condensate EBC 低成本高效率的呼出气体冷凝物采样装置 EBC
Advanced Sensor Research Pub Date : 2024-03-01 DOI: 10.1002/adsr.202400020
Mehran Khorshid, Soroush Bakhshi Sichani, Dimna L. Barbosa Estrada, Werner Neefs, Alexander Clement, Gerhard Pohlmann, Ralph Epaud, Sophie Lanone, Patrick Wagner
{"title":"An Efficient Low-Cost Device for Sampling Exhaled Breath Condensate EBC","authors":"Mehran Khorshid,&nbsp;Soroush Bakhshi Sichani,&nbsp;Dimna L. Barbosa Estrada,&nbsp;Werner Neefs,&nbsp;Alexander Clement,&nbsp;Gerhard Pohlmann,&nbsp;Ralph Epaud,&nbsp;Sophie Lanone,&nbsp;Patrick Wagner","doi":"10.1002/adsr.202400020","DOIUrl":"10.1002/adsr.202400020","url":null,"abstract":"<p>While exhaled breath condensate EBC is not yet used in routine clinical diagnostics and disease monitoring, recent publications indicate that exhaled air and EBC contain a wide range of molecular biomarkers that are characteristic of various medical conditions. This includes evidently lung disorders such as asthma, COPD, and cystic fibrosis, but also diabetes and several types of cancer go along with specific biomarkers exhaled from the airways. In addition, EBC samples can be collected in a non-invasive way and, due to their small volume, they can be easily stored frozen between collection and analysis. Several home-made EBC-collection systems for research purposes are documented in literature while there are also a few systems from commercial suppliers that are not yet certified as medical products. In this work, a novel collection device is presented in which the EBC is condensed and frozen inside stainless steel tubes, tightly surrounded by an aluminum cylinder that is precooled in a kitchen freezer. The device is low cost, easy to use by patients at home or in a clinic, and its collection efficiency of up to 500 µL min<sup>−1</sup> of respiration is on the high side.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"3 7","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140279545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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