Advanced Sensor Research最新文献

Cortisol Dynamics at High Temporal Resolution For Wearable Biosensor Research 可穿戴生物传感器研究中高时间分辨率的皮质醇动态

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Advanced Sensor Research Pub Date : 2026-10-14 DOI: 10.1002/adsr.70212

Munia Ferdoushi, Tess Billings, Wenxin Cai, Yasser Khan

{"title":"Cortisol Dynamics at High Temporal Resolution For Wearable Biosensor Research","authors":"Munia Ferdoushi, Tess Billings, Wenxin Cai, Yasser Khan","doi":"10.1002/adsr.70212","DOIUrl":"https://doi.org/10.1002/adsr.70212","url":null,"abstract":"Cortisol is a dynamic endocrine biomarker regulated by hypothalamic–pituitary–adrenal (HPA) axis activity, and plays a central role in circadian regulation and physiological stress responsiveness. This review summarizes key aspects of cortisol dynamics, including circadian rhythms, modulatory factors, dysregulation, and acute and chronic stress responses. We further examine commonly used laboratory stress-induction paradigms, such as the Trier Social Stress Test, Cold Pressor Test, Maastricht Acute Stress Test, cognitive stressors, and multicomponent stress protocols, with an emphasis on their applicability to wearable cortisol sensor development. Particular attention is given to experimental design considerations, including the choice of sampling matrix, sensor-influenced temporal resolution, and acquisition frequency, as these parameters critically influence the interpretation of cortisol fluctuations and define the performance requirements of sensing platforms. To complement the literature review, we additionally report preliminary observations from a pilot study involving three healthy adult participants. The pilot experiments explore the feasibility of selected stress-induction protocols for eliciting measurable stress responses using a dense temporal sampling protocol. By integrating insights from prior studies with our pilot observations, we highlight methodological considerations for capturing physiologically meaningful cortisol responses to stress, with a specific focus on stress-induced dynamics and the temporal resolution necessary for continuous or near-continuous monitoring.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 10","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70212","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149205611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Detection Range Setting via Electropolymerization of Molecularly Imprinted Polymers With Plasmonic Optical Fiber Probes – The Case Study of Caffeine as a Small Molecule 等离子体光纤探针在分子印迹聚合物电聚合中的检测范围设置——以小分子咖啡因为例

IF 5

Advanced Sensor Research Pub Date : 2026-10-09 DOI: 10.1002/adsr.70181

Rosalba Pitruzzella, Alessandra Cutaia, Chiara Marzano, Luigi Zeni, Giancarla Alberti, Nunzio Cennamo

{"title":"Detection Range Setting via Electropolymerization of Molecularly Imprinted Polymers With Plasmonic Optical Fiber Probes – The Case Study of Caffeine as a Small Molecule","authors":"Rosalba Pitruzzella, Alessandra Cutaia, Chiara Marzano, Luigi Zeni, Giancarla Alberti, Nunzio Cennamo","doi":"10.1002/adsr.70181","DOIUrl":"https://doi.org/10.1002/adsr.70181","url":null,"abstract":"In this work, by exploiting in situ electropolymerization of molecularly imprinted polymer (eMIP) layers over surface plasmon resonance (SPR) optical fiber probes, the capability to extend the analyte detection concentration range by tuning eMIP layer thickness is demonstrated. More specifically, in this proof-of-concept sensing strategy, the caffeine was used as a template in order to evaluate the responses of the sensors in the detection of a small molecule. Two sensor configurations are designed, developed, and tested exploiting two eMIP layers with different thicknesses combined with the same SPR plastic optical fiber (POF) platform. The experimental results demonstrated that two detection ranges, in the femtomolar and picomolar ranges, were achieved using the developed sensor configurations. Moreover, the developed SPR-POF-eMIP sensors offer several advantages, including high selectivity, a fast response time (about 10 min), the intrinsic versatility of eMIP coding, small-size and low-cost sensor chips, and a portable and simple setup (reader).","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 10","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70181","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149146333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gold-Leaf-Based Plant-Wearable Electronic Tattoos for Temperature Monitoring in Smart Agriculture 基于金叶的植物可穿戴电子纹身在智能农业中的温度监测

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Advanced Sensor Research Pub Date : 2026-10-06 DOI: 10.1002/adsr.70206

Snezana M. Djuric, Damir Krkljes, Georges Dubourg, Nikola M. Djuric

{"title":"Gold-Leaf-Based Plant-Wearable Electronic Tattoos for Temperature Monitoring in Smart Agriculture","authors":"Snezana M. Djuric, Damir Krkljes, Georges Dubourg, Nikola M. Djuric","doi":"10.1002/adsr.70206","DOIUrl":"https://doi.org/10.1002/adsr.70206","url":null,"abstract":"In this work, substrate-free resistive electronic tattoo temperature sensors are introduced, consisting of a laser-patterned gold leaf electrode transferred directly onto the leaf surface using removable commercial tattoo paper. Three sensor geometries are fabricated and evaluated, all showing a linear resistance–temperature response, good signal stability during continuous measurements, and repeatable behavior under cyclic heating and cooling. One selected geometry is integrated into a low-cost measurement platform combining an Arduino MKR WiFi 1010 microcontroller, Bluetooth communication, and a dedicated Android application. Measurements in an environmental chamber show excellent agreement between the electronic tattoo sensor and a reference thermocouple, with a standard deviation of less than 0.5°C on tattoo paper. The sensor is then transferred onto a living Clusia leaf and demonstrates accurate real-time temperature monitoring, with a standard deviation of the reading difference of less than 0.1°C during 8 h of operation. Robustness testing under mechanical and environmental stress conditions demonstrates that the selected tattoo sensor maintains electrical continuity and attachment during repeated deformation, high-humidity exposure, and accelerated thermal dehydration. The substrate-free sensor configuration and wireless smartphone-based readout demonstrate the potential of gold-leaf-based electronic tattoos for minimally intrusive plant monitoring and smart agriculture.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 10","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70206","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Extended-Gate-Type Organic Field-Effect Transistors for Label-Free Immunosensing 用于无标签免疫传感的扩展栅型有机场效应晶体管

IF 5

Advanced Sensor Research Pub Date : 2026-10-06 DOI: 10.1002/adsr.70207

Yui Sasaki, Tsuyoshi Minami

{"title":"Extended-Gate-Type Organic Field-Effect Transistors for Label-Free Immunosensing","authors":"Yui Sasaki, Tsuyoshi Minami","doi":"10.1002/adsr.70207","DOIUrl":"https://doi.org/10.1002/adsr.70207","url":null,"abstract":"Organic field-effect transistors (OFETs) are electronic devices that exhibit switching behavior upon application of a gate voltage, and their device characteristics make them attractive platforms for bio/chemical sensing in analytical chemistry. However, the limited operational stability of many organic semiconductor layers in aqueous environments poses challenges for sensing applications, including those involving body fluids. To address this bottleneck, this Perspective focuses on the extended-gate architecture, which physically separates the aqueous sensing interface from the organic semiconductor and can thereby improve operational stability. The extended-gate surface can be chemically functionalized with recognition materials, such as antibodies, to introduce molecular recognition toward target analytes. The reported devices have demonstrated label-free electrical responses to target biomarkers under their respective experimental conditions. Herein, representative extended-gate architectures, including separated, semi-integrated, and pseudo-reference-integrated configurations, are introduced. Representative surface-engineering strategies for label-free immunosensing are also described. Finally, the remaining challenges for translation to biomarker analysis are discussed.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 10","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front Cover: Extended-Gate-Type Organic Field-Effect Transistors for Label-Free Immunosensing (Adv. Sensor Res. 10/2026) 前盖：用于无标签免疫传感的扩展栅型有机场效应晶体管（ad . Sensor Res. 10/2026）

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Advanced Sensor Research Pub Date : 2026-10-02 DOI: 10.1002/adsr.70215

Yui Sasaki, Tsuyoshi Minami

引用次数: 0

Recent Advances in Chemosensors Bearing Pyrazole and Imidazole Rings: An Approach Toward the Detection of Metal Ions Based on these Diazoles 含吡唑环和咪唑环的化学传感器研究进展：基于这些重唑环的金属离子检测方法

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Advanced Sensor Research Pub Date : 2026-10-02 DOI: 10.1002/adsr.70204

Alexander Ladino-Bejarano, Carlos Cifuentes, Néstor Bravo, Jaime Portilla

{"title":"Recent Advances in Chemosensors Bearing Pyrazole and Imidazole Rings: An Approach Toward the Detection of Metal Ions Based on these Diazoles","authors":"Alexander Ladino-Bejarano, Carlos Cifuentes, Néstor Bravo, Jaime Portilla","doi":"10.1002/adsr.70204","DOIUrl":"https://doi.org/10.1002/adsr.70204","url":null,"abstract":"The optical detection of metal ions via ligand-metal interactions has attracted attention in recent years, driven by advances in organic dyes and the crucial role of metals in nature and industry. Aza-heterocyclic compounds (AHCs) are promising dyes for this purpose due to their tunable electronic properties and metal-coordinating ability. Among these, pyrazole and imidazole rings have been explored as recognition and signaling units in fluorescent and colorimetric probes. They offer coordination capacity, stability, and notable synthetic accessibility, making them particularly attractive for developing efficient chemosensors. Metals are common analytes in biological, environmental, and materials sciences; for example, excess metal ions can cause serious ecological and health problems, underscoring the need for efficient and selective recognition methods. In general, pyrazole and imidazole derivatives are promising scaffolds for developing more efficient and selective probes for sensing metal ions; this contribution focuses on representative probe examples with these two ring types reported in the last 5 years.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 10","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70204","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149099290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Issue Information (Adv. Sensor Res. 10/2026) 发布信息（ad . Sensor Res. 10/2026）

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Advanced Sensor Research Pub Date : 2026-10-02 DOI: 10.1002/adsr.70216

引用次数: 0

Three-Dimensional Water Flow Vector Sensor using an Absolute Pressure Sensor Array on a Dodecahedral Origami Substrate 基于绝对压力传感器阵列的十二面体折纸基板三维水流矢量传感器

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Advanced Sensor Research Pub Date : 2026-09-27 DOI: 10.1002/adsr.70211

Ryusei Ando, Takuto Kishimoto, Kyota Shimada, Hidetoshi Takahashi

{"title":"Three-Dimensional Water Flow Vector Sensor using an Absolute Pressure Sensor Array on a Dodecahedral Origami Substrate","authors":"Ryusei Ando, Takuto Kishimoto, Kyota Shimada, Hidetoshi Takahashi","doi":"10.1002/adsr.70211","DOIUrl":"https://doi.org/10.1002/adsr.70211","url":null,"abstract":"Recent marine applications, including aquaculture monitoring and underwater drones, demand compact, energy-efficient sensors for three-dimensional (3D) water flow measurement. However, conventional 3D water flow sensors are typically bulky and energy-intensive, limiting their use in such systems. This study proposes a lightweight, low-power 3D water flow vector sensor that integrates multiple absolute pressure elements on a spherical housing. The surface pressure pattern, which varies with flow speed and angle, is analyzed using a neural network regression model to estimate 3D flow vectors. The use of absolute pressure sensors simplifies fabrication, while a dodecahedral Kiri-origami substrate enables a compact and symmetric arrangement of the sensor elements. This simple sensor design, combining the Kiri-origami substrate and low-power pressure sensors, results in a total weight of approximately 0.1 kg and a power consumption of approximately 55 mW. Simulation-based evaluation confirms high estimation accuracy with low angular dependence, and water-tunnel experiments demonstrate the sensor's sensitivity to flow variations. The trained model achieves a speed error of 0.03 m/s and an angular error of 5° for flow speeds of 0.4 m/s or above. These results demonstrate the proposed sensor's potential as a compact and energy-efficient solution for 3D marine flow measurements.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70211","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149146532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurofluid Biomarker Sensors: Integrated Design Strategies From Molecular Recognition to Precision Neurological Diagnosis 神经流体生物标记传感器：从分子识别到精确神经诊断的集成设计策略

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Advanced Sensor Research Pub Date : 2026-09-25 DOI: 10.1002/adsr.70209

Ting Li, Guoying Pan, Yuheng Wang, Xin Zou, Hui Yang

{"title":"Neurofluid Biomarker Sensors: Integrated Design Strategies From Molecular Recognition to Precision Neurological Diagnosis","authors":"Ting Li, Guoying Pan, Yuheng Wang, Xin Zou, Hui Yang","doi":"10.1002/adsr.70209","DOIUrl":"https://doi.org/10.1002/adsr.70209","url":null,"abstract":"The occurrence, progression, and treatment of neurological diseases are accompanied by complex humoral chemical changes, including ion imbalances, neurotransmitter disturbances, metabolic abnormalities, and abnormally elevated levels of inflammatory factors and pathological proteins. These molecular dynamics often precede the onset of clinical symptoms. Therefore, real-time and accurate monitoring of these neurofluid biomarkers is crucial for early disease diagnosis, efficacy evaluation, and mechanistic research. However, the cerebrospinal fluid, interstitial fluid, and brain tissue microenvironment are complex, including factors such as low target molecule content, rapid changes in the microenvironment, strong background interference, and the risk of tissue damage, making neurofluid monitoring extremely challenging and thus driving the development of various advanced sensing technologies. Unlike previous reviews that primarily focused on single sensor modalities or specific biomarker classes, this review uniquely integrates the transducer-based classifications (electrochemical, optical, mechanical, and multimodal platforms) in neurofluid sensing technologies and design strategies driven by different classes of neurofluid biomarkers (ions, neurotransmitters, metabolites, and inflammatory proteins). Furthermore, this review summarizes the challenges and future development directions of neurofluid sensors, providing a comprehensive and interdisciplinary framework aimed at offering a systematic reference and future development guidance for promoting the development of intelligent, highly sensitive, and clinically translatable neurofluid sensing technologies.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70209","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149048575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Proton-Radiation-Tolerant Silicon Photonic Charge Sensor for Spacecraft Applications 用于航天器的耐质子辐射硅光子电荷传感器

IF 5

Advanced Sensor Research Pub Date : 2026-09-22 DOI: 10.1002/adsr.70208

Wataru Takahama, Kosei Otsuka, Ayumi Ishihara, Rikuto Hojo, Tomofumi Mogami, Kazuhiro Toyoda, Kohtaku Suzuki, Yasushi Takahashi

{"title":"Proton-Radiation-Tolerant Silicon Photonic Charge Sensor for Spacecraft Applications","authors":"Wataru Takahama, Kosei Otsuka, Ayumi Ishihara, Rikuto Hojo, Tomofumi Mogami, Kazuhiro Toyoda, Kohtaku Suzuki, Yasushi Takahashi","doi":"10.1002/adsr.70208","DOIUrl":"https://doi.org/10.1002/adsr.70208","url":null,"abstract":"Silicon waveguides are promising platforms for spacecraft potential sensing owing to their compactness and immunity to electromagnetic interference. However, proton-induced optical absorption in operating silicon waveguides has not been quantitatively clarified, despite their direct exposure to the space radiation environment during spacecraft operation. Here, we present a systematic elucidation of proton-radiation effects on a photonic charge sensor based on silicon photonic crystal waveguides. During proton irradiation at 20 keV, we quantitatively evaluate the increase in optical absorption under device operation and find that a fluence of 1.0 × 1014 cm−2 induces an additional absorption coefficient of approximately 0.41 cm−1. We further demonstrate that the sensor retains its ability to measure spacecraft potential even after exposure to a high proton fluence of 1.0 × 1015 cm−2, confirming its intrinsic radiation tolerance. These results establish the radiation robustness of silicon-waveguide-based sensing mechanisms and provide the first quantitative basis for implementing photonic charge sensors in radiation-rich spacecraft environments.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"5 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70208","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149048352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0