Ryan A. Williams, Grace A. R. Rohaley, Ashwathanarayana Gowda, Gisele Pegorin, Andrea Oprandi, Denis Motovilov, Anthony Schneider, Elda Hegmann, Marianne E. Prévôt, Torsten Hegmann
{"title":"Zero-Power, Optical Toxic Gas and Vapor Sensors Utilizing Printed Nematic Liquid Crystal Patterns on Selectively Reactive Substrates (Adv. Sensor Res. 6/2025)","authors":"Ryan A. Williams, Grace A. R. Rohaley, Ashwathanarayana Gowda, Gisele Pegorin, Andrea Oprandi, Denis Motovilov, Anthony Schneider, Elda Hegmann, Marianne E. Prévôt, Torsten Hegmann","doi":"10.1002/adsr.70023","DOIUrl":"https://doi.org/10.1002/adsr.70023","url":null,"abstract":"<p><b>Toxic Gas Sensors for Firefighters</b></p><p>Toxic gas sensors for the detection of chlorine and phosgene are reported utilizing inkjet printed nematic liquid crystal patterns on reactive substrates. The zero-power sensors are characterized by high sensitivity at relevant ppm and ppb levels, fast response times on the order of seconds, and a design that is highly customizable by the potential end user. More details can be found in article 2400166 by Marianne E. Prévôt, Torsten Hegmann, and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70023","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stefano Lai, Roberto Cusano, Alessandra Scano, Giorgio Fotia, Annalisa Bonfiglio
{"title":"Organic Transistor-Based Biosensors for Viral RNA Detection and Variant Monitoring: From SARS-CoV-2 to Effective Management of Future Pandemics","authors":"Stefano Lai, Roberto Cusano, Alessandra Scano, Giorgio Fotia, Annalisa Bonfiglio","doi":"10.1002/adsr.70000","DOIUrl":"https://doi.org/10.1002/adsr.70000","url":null,"abstract":"<p>The COVID-19 crisis has defined the need of novel approaches for a straightforward management of pandemic and epidemic conditions. Here, an approach based on electronic sensing of viral RNA is proposed for both virus detection and variant tracking. The sensing strategy of the Organic Charge-Modulated Field-Effect Transistor (OCMFET) is employed for the development of a multi-sensing platform, capable of parallel evaluation of control references and investigated samples. PCR-free detection of viral genomic RNA is demonstrated at different target concentrations, with optimal discrimination with respect to negative control. Moreover, the same approach is feasible for virus variant tracking, as a screening strategy for mutation detection in PCR-amplified samples: the approach can be used for a rationalization of RNA sequencing procedures, which are difficult to perform in the acute phases of pandemics, but are fundamental for an effective pandemic management. The results pave the way for novel strategies to enhance cost-effectiveness, easiness-of-use in combination with selectivity and sensitivity in virus detection during severe pandemic conditions, and a more effective variant tracking by optimizing the access to sequencing resources even during the acute phases of pandemic.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70000","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A High-Performance Miniaturized Frequency Shift Detection System for QCM-Based Gravimetric Sensing (Adv. Sensor Res. 5/2025)","authors":"Chenyang Gao, Shuyu Fan, Wei Li, Yongbing Wang, Qianwen Xia, Dibo Hou, Yunqi Cao","doi":"10.1002/adsr.70006","DOIUrl":"https://doi.org/10.1002/adsr.70006","url":null,"abstract":"<p><b>Quartz Crystal Microbalance</b></p><p>A miniaturized frequency shift detection system based on a phase-locked loop (PLL) circuit is proposed for simplifying quartz crystal microbalance (QCM) measurement, possessing excellent performance of high sensitivity, resolution, linearity, and accuracy compared with a commercial frequency analyzer. The proposed system has the potential for enabling long-term, in-situ detection, and promoting large-scale applications of QCM. More details can be found in article 2400148 by Yunqi Cao and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143919827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives (Adv. Sensor Res. 5/2025)","authors":"Lili Liang, Fei Xie, Li Jin, Bowen Yang, Li-Peng Sun, Bai-Ou Guan","doi":"10.1002/adsr.70005","DOIUrl":"https://doi.org/10.1002/adsr.70005","url":null,"abstract":"<p><b>Optical Microfiber Biomedical Sensors</b></p><p>Optical microfiber biosensors, a revolutionary biomedical technology, offer high sensitivity, specificity, and versatility for biomarker detection, health monitoring, and treatment. This review highlights their significance, examines recent advancements, challenges, and outlines future developments. More details can be found in article 2400185 by Li-Peng Sun and co-workers.\u0000\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70005","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143919826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haosen Miao, Gririraj Manoharan, Ahran Lim, Peter Mirau, Jorge L. Chávez, Chang-Seuk Lee, Matteo Palma
{"title":"Modulating Signal Generation in Aptamer-Based CNT-FET Biosensors by Controlling the Functionalization Route","authors":"Haosen Miao, Gririraj Manoharan, Ahran Lim, Peter Mirau, Jorge L. Chávez, Chang-Seuk Lee, Matteo Palma","doi":"10.1002/adsr.70002","DOIUrl":"https://doi.org/10.1002/adsr.70002","url":null,"abstract":"<p>The identification of biomarkers is key to the early detection of physiological dysfunction. Nanoscale field-effect transistors (FETs) modified with target-specific receptors enable direct target sensing, offering enhanced sensitivity due to nanoscale channel confinement. In this regard, single-walled carbon nanotubes (SWCNTs) have emerged as strong candidates for the development of transistor-based biosensors. Understanding the structural parameters that affect sensing performance in such nanoscale electrical detection platforms is essential for their reliable and controllable use. Here, this is investigated that how different assembly strategies employed in the construction of nanoscale aptamer-based SWCNT-FET biosensors can dramatically affect their signal generation, with conductance increasing or decreasing for the same aptamer-cortisol recognition event. a cortisol-binding DNA aptamer exhibiting well-characterized conformational behavior is employed, as a model receptor to explore the influence of different surface functionalization strategies on SWCNT-based biosensors performance. Through combined electrical and optical characterization, this is elucidated that how aptamer conformation governs local electrostatic changes within the Debye length, which in turn modulates the electrostatic gating of the devices. This work offers insight into effective design strategies for the construction of biosensors functionalized with electrostatically active molecular receptors.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christopher Heuer, Anton Enders, Steffen Winkler, Martin Klaßen, Thorsten Teutenberg, Janina Bahnemann
{"title":"A 3D-Printed Microfluidic Sensor Platform for Online Bioprocess Monitoring","authors":"Christopher Heuer, Anton Enders, Steffen Winkler, Martin Klaßen, Thorsten Teutenberg, Janina Bahnemann","doi":"10.1002/adsr.70001","DOIUrl":"https://doi.org/10.1002/adsr.70001","url":null,"abstract":"<p>In order to screen for optimal bioprocess parameters at higher throughput, researchers developing new biopharmaceuticals are increasingly turning to miniaturized cultivation systems with reduced space and media consumption. However, these systems still face challenges related to the continuous monitoring of critical bioprocess parameters, in particular, because sensor integration is often difficult, and sample volumes for offline measurements are limited. In this work, a novel 3D-printed microfluidic lab-on-a-chip sensor platform is presented, specifically designed to be compatible with a range of cultivation systems (including shake flasks, bioreactors, and custom microbioreactors). The microfluidic system acts as a miniaturized bypass, integrating sensors for real-time monitoring of key bioprocess parameters (such as pH, pO₂, pCO₂, glucose, and lactate) without compromising culture volume. This system has been successfully applied in a proof-of-concept for the cultivation of <i>Escherichia coli</i> and <i>Saccharomyces cerevisiae</i>. In addition, this platform also includes an integrated sampling unit for small-volume collection, thereby potentially enabling the analysis of complex analyte mixtures such as amino acids or recombinant proteins. The presented system thus represents a valuable tool for both real-time online monitoring and offline analysis, contributing to the optimization of biopharmaceutical production processes.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.70001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hankun Yang, Monsur Islam, Vanessa Trouillet, Martin Sommer, Jan G. Korvink, Uli Lemmer, Bharat Sharma
{"title":"Electrospun Vanadium Pentoxide (V2O5) Nanofibers for Enhanced Humidity Sensing","authors":"Hankun Yang, Monsur Islam, Vanessa Trouillet, Martin Sommer, Jan G. Korvink, Uli Lemmer, Bharat Sharma","doi":"10.1002/adsr.202500040","DOIUrl":"https://doi.org/10.1002/adsr.202500040","url":null,"abstract":"<p>Adequate humidity monitoring is crucial for many industrial and consumer applications. Among various moisture-absorbing materials, 2D materials are potential contestants for fabricating humidity sensors owing to their fascinating ultra-high surface-to-volume ratio, abundant active sites, and large carrier mobilities. In this work, vanadium pentoxide (V<sub>2</sub>O<sub>5</sub>) nanofibers (NFs) produced by a facile electrospinning method using VO(acac)2 10% Polyacrylonitrile/Dimethylformamid are showcased for humidity sensing. The annealing temperature-dependent (400–600 °C) variations in morphology and composition of the electrospun V<sub>2</sub>O<sub>5</sub> NFs are studied by structural and physicochemical characterization methods. Subsequently, the V<sub>2</sub>O<sub>5</sub> NFs are effectively used for humidity sensing at room temperature (RT). It is demonstrated that the optimum RT humidity response and sensitivity of the NF sensor are obtained at an annealing temperature of 500 °C with a high surface area of 14.8 m<sup>2</sup>g<sup>−1</sup> containing large porous fibers ranging from 200 to 500 nm diameter. The synthesized V<sub>2</sub>O<sub>5</sub> NF sensor exhibits high sensitivity to water at RT (max. 1.427 at 90 %RH), excellent linearity, wide range (10–90%RH), and quick response and recovery times. This work sets a benchmark for designing novel V<sub>2</sub>O<sub>5</sub>-based RT humidity sensing devices.</p>","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202500040","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144273212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}