Advanced Sensor Research最新文献_第3页

In Situ Growth of The Interpenetrating Structure UiO-66-NH2/MWCNTs-OH for The Detection of Phosphoproteins in Human Sweat UiO-66-NH2/MWCNTs-OH互穿结构原位生长检测人体汗液中磷酸化蛋白

Advanced Sensor Research Pub Date : 2025-02-15 DOI: 10.1002/adsr.202400130

Zhiye Ying, Ce Bian, Lijuan Qiao, Bingxin Liu, Li Gao

{"title":"In Situ Growth of The Interpenetrating Structure UiO-66-NH2/MWCNTs-OH for The Detection of Phosphoproteins in Human Sweat","authors":"Zhiye Ying, Ce Bian, Lijuan Qiao, Bingxin Liu, Li Gao","doi":"10.1002/adsr.202400130","DOIUrl":"https://doi.org/10.1002/adsr.202400130","url":null,"abstract":"Phosphorylated proteins in human sweat are found to be closely associated with neurodegenerative diseases, including Alzheimer's disease. Real-time, non-invasive detection of changes in the types and levels of phosphorylated proteins in sweat is of significant clinical value for the prevention and diagnosis of these diseases. This research introduces an electrochemical sensor based on an in situ-grown interpenetrating network structure of UiO-66-NH2/MWCNTs-OH, specifically designed for detecting phosphorylated proteins in sweat. The sensor is tested with common phosphorylated and non-phosphorylated proteins, demonstrating excellent selectivity, repeatability, reproducibility, and stability, with a limit of detection as low as 0.28 µmol L−1. Additionally, biotoxicity experiments conducted on SD rats and volunteers show that UiO-66-NH2/MWCNTs-OH is biologically safe, making it suitable for use as a biosensor. Finally, the fabrication of the electrochemical sensing module provides a foundation for the development of subsequent wearable sensors.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400130","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computer-Aided Design of Integrated Digital Strain Sensors for Hardware-Based Recognition and Quantification of Human Movements 基于硬件识别和量化人体运动的集成数字应变传感器的计算机辅助设计

Advanced Sensor Research Pub Date : 2025-02-14 DOI: 10.1002/adsr.202400146

Hudson Gasvoda, Mengchu Li, Andrea Pader, Rana Altay, Nick Cmager, Tripti Pandey, Tsun-Ming Tseng, Ismail Emre Araci

{"title":"Computer-Aided Design of Integrated Digital Strain Sensors for Hardware-Based Recognition and Quantification of Human Movements","authors":"Hudson Gasvoda, Mengchu Li, Andrea Pader, Rana Altay, Nick Cmager, Tripti Pandey, Tsun-Ming Tseng, Ismail Emre Araci","doi":"10.1002/adsr.202400146","DOIUrl":"https://doi.org/10.1002/adsr.202400146","url":null,"abstract":"An integrated strain sensor system that has a unique response to a specific (set of) human movement(s) has the potential to impact various musculoskeletal health tracking applications akin to the step counter's impact on physical activity tracking. It is determined that an open circuit state of a sensor can be used as such a unique response. With this consideration, a digital strain sensor (DigSS) that exhibits a binary (i.e., ON/OFF) response when a threshold strain level is exceeded is developed. The channel geometry dependence of the corner flow in capillaric strain sensors (CSS) resulting in an electrofluidic switch is used. It is demonstrated that through the coalescence and breakup of a liquid meniscus, DigSS operates for hundreds of cycles with a strain limit of detection of 0.0026. To facilitate integration, a linear optimization-based computer-aided design tool for the integrated DigSS (iDigSS) is created. Experimental validation shows that the iDigSS distinguishes a target strain-field profile from 35 of 36 theoretically distinguishable profiles without requiring signal processing. Human subject trials demonstrate the system's ability to differentiate a specific shoulder movement from five others and to wirelessly record wrist extension counts and durations.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Portable and Low-Cost Single Board Computer-Based Spectrophotometric Platform for Optical Analysis in the UV and Visible Range 一种便携式、低成本的基于单片机的紫外和可见光光谱分析平台

Advanced Sensor Research Pub Date : 2025-02-14 DOI: 10.1002/adsr.202400163

Alessandro Tonelli, Anna Tortone, Alessandro Grazioli, Francesco Pasquali, Michele Sozzi, Alessandro Candiani, Luca Capelli, Alessandro Bertucci

{"title":"A Portable and Low-Cost Single Board Computer-Based Spectrophotometric Platform for Optical Analysis in the UV and Visible Range","authors":"Alessandro Tonelli, Anna Tortone, Alessandro Grazioli, Francesco Pasquali, Michele Sozzi, Alessandro Candiani, Luca Capelli, Alessandro Bertucci","doi":"10.1002/adsr.202400163","DOIUrl":"https://doi.org/10.1002/adsr.202400163","url":null,"abstract":"The growing ability of high-performance consumer electronics is fostering innovation in prototyping and research. Although the Raspberry Pi single-board computer (SBC) is widely used across various fields, including diagnostics, applications involving UV-based reading remain underexplored. In this study, a simple, low-cost (less than 100 euros), and portable device for UV–vis measurements based on Raspberry Pi is presented. The system integrates the AS7341 multi-channel multispectral digital sensor, offering analytical performance comparable to two commercial spectrophotometers – one benchtop and one portable – in terms of linearity, limit of detection, quantitation, and repeatability. Furthermore, the device demonstrates reliable performance both in analyzing real wine samples using two different commercial enzymatic kits and in quantifying different concentrations of synthetic DNA oligonucleotides. By providing a ready-to-use, portable, and affordable platform for UV–vis diagnostics, this prototype is well-suited for resource-limited settings, educational environments, and IoT applications where numerous distributed sensors are required for specific diagnostic tasks.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143818706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Complementary Cost-Effective Electrochemical Platforms for Point-Of-Use Biosensing (Adv. Sensor Res. 2/2025) 用于点生物传感的互补的具有成本效益的电化学平台（ad . Sensor Res. 2/2025）

Advanced Sensor Research Pub Date : 2025-02-10 DOI: 10.1002/adsr.202570004

Mason Monaco, Marjon Zamani, Ava Sarram, Chao-Chi Kuo, Chathurika Abeyrathne, Miaosi Li, Ariel L. Furst

引用次数: 0

Issue Information (Adv. Sensor Res. 2/2025) 发布信息（Adv. Sensor Res. 2/2025）

Advanced Sensor Research Pub Date : 2025-02-10 DOI: 10.1002/adsr.202570005

引用次数: 0

Sensor-enabled Orthopedic Implants for Musculoskeletal Monitoring 用于肌肉骨骼监测的传感器骨科植入物

Advanced Sensor Research Pub Date : 2025-02-09 DOI: 10.1002/adsr.202400138

Jincai Huang, Hanqing Dong, Wanmei Zhang, Jixin Cui, Qingang Li, Junqiang Wang, Zhe Zhao, Xining Zang

引用次数: 0

A Standalone and Quantitative Point-of-Need Testing Platform with Manual Readout Capability Based on Smart Hydrogel Strands 基于智能水凝胶链的手动读出能力的独立定量点需求测试平台

Advanced Sensor Research Pub Date : 2025-02-09 DOI: 10.1002/adsr.202400134

Saeed Boroomand, Navid Farhoudi, Christopher F. Reiche, Jules J. Magda, Florian Solzbacher, Lars B. Laurentius

{"title":"A Standalone and Quantitative Point-of-Need Testing Platform with Manual Readout Capability Based on Smart Hydrogel Strands","authors":"Saeed Boroomand, Navid Farhoudi, Christopher F. Reiche, Jules J. Magda, Florian Solzbacher, Lars B. Laurentius","doi":"10.1002/adsr.202400134","DOIUrl":"https://doi.org/10.1002/adsr.202400134","url":null,"abstract":"Smart hydrogels hold great promise as sensing elements that can be tailored to respond to a wide array of biomarkers and can be integrated with different readout modalities. However, a major challenge with these sensors is response time, which depends on the hydrogel swelling behavior and is limited by diffusion. While geometrical miniaturization can accelerate response time, it often requires complex readout systems to detect volume changes, which is detrimental for use in point-of-need (PoN) applications. This study introduces a novel approach for hydrogel-based platforms that realizes important PoN requirements such as sensitivity, cost-effectiveness, instrument-free, and fast response time. The proposed sensing mechanism involves constraining a hydrogel strand at both ends and utilizing a visually observable buckling behavior instead of directly measuring a volume change. The sensing principle is validated by measuring glucose, an important biological analyte, and examines measurement repeatability, response time, sensitivity, and dynamic range. The performance is also demonstrated in blood and serum. The effects of design parameters such as strand length and diameter on sensor performance are also investigated. This new sensor offers a straightforward visual readout without requiring complex instrumentation, paving the way for more accessible and affordable PoN devices.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrocrystallization of Copper 7,7,8,8-Tetracyanoquinodimethane Charge-Transfer Complex on Flexible Substrates for Real-Time Ammonia Gas Sensing 铜7,7,8,8-四氰喹诺二甲烷电荷转移配合物在柔性衬底上的电结晶用于实时氨气传感

Advanced Sensor Research Pub Date : 2025-02-02 DOI: 10.1002/adsr.202400167

Ren Wang, Mohamed Kilani, Jiancheng Lin, Rona Chandrawati, Guangzhao Mao

{"title":"Electrocrystallization of Copper 7,7,8,8-Tetracyanoquinodimethane Charge-Transfer Complex on Flexible Substrates for Real-Time Ammonia Gas Sensing","authors":"Ren Wang, Mohamed Kilani, Jiancheng Lin, Rona Chandrawati, Guangzhao Mao","doi":"10.1002/adsr.202400167","DOIUrl":"https://doi.org/10.1002/adsr.202400167","url":null,"abstract":"Real-time monitoring of public safety, individual health, and environmental conditions relies on accurate continuous data collected by gas sensors, which provide users with cost-effective insights to support informed decision-making. This study presents an innovative approach that simplifies the manufacturing process of nanowire (NW)-based gas sensors by enabling direct electrodeposition of NW crystals on various substrates, such as silicon wafers and polyethylene terephthalate (PET). Copper 7,7,8,8-Tetracyanoquinodimethane (CuTCNQ), a charge-transfer complex, is electrodeposited directly onto photolithographically patterned interdigitated triangle-tip electrodes and functions as a chemiresistive gas sensor that responds to ammonia gas through charge interactions. The sensor's performance can be precisely controlled using electrochemical techniques, allowing for tailored sensitivity across different concentration ranges. To enhance the practical application of this technology, a flexible, near-field communication-based passive tag is developed by integrating the CuTCNQ gas sensor with a flexible printed circuit board. This device enables on-demand ammonia concentration analysis and operates battery-free and wireless through mobile phone scanning. This capability is crucial for wearable or industrial devices and aligns with the increasing demand for robust environmental monitoring solutions. This approach represents a significant step forward in improving both human health and environmental protection through accessible and efficient gas sensing technology.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400167","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ultrathin Screen-Printed Plant Wearable Capacitive Sensors for Environmental Monitoring 用于环境监测的超薄丝网印刷植物可穿戴电容式传感器

Advanced Sensor Research Pub Date : 2025-01-28 DOI: 10.1002/adsr.202400177

Elliot J. Strand, Anupam Gopalakrishnan, Catherine A. Crichton, Mallory J. Palizzi, Owen Lee, Tomoko Borsa, Eloise Bihar, Payton Goodrich, Ana Claudia Arias, Sean E. Shaheen, Robert R. McLeod, Gregory L. Whiting

{"title":"Ultrathin Screen-Printed Plant Wearable Capacitive Sensors for Environmental Monitoring","authors":"Elliot J. Strand, Anupam Gopalakrishnan, Catherine A. Crichton, Mallory J. Palizzi, Owen Lee, Tomoko Borsa, Eloise Bihar, Payton Goodrich, Ana Claudia Arias, Sean E. Shaheen, Robert R. McLeod, Gregory L. Whiting","doi":"10.1002/adsr.202400177","DOIUrl":"https://doi.org/10.1002/adsr.202400177","url":null,"abstract":"Printable and wearable plant sensors offer an approach for collecting critical environmental data at high spatial resolution to understand plant conditions and aid land management practices. Here, screen printed capacitive devices that can measure relative humidity (RH) directly at the plant-environment interface, are demonstrated in an ultra-thin (<6 µm) form factor. Using screen printing and a temporary tattoo transfer process, a simple technique is established to: 1) enclose printed electronic features between two layers of ethyl cellulose (EtC), 2) mount printed microparticle carbon-based electronics onto a variety of plant structures, and 3) dramatically increase the capacitance and sensitivity for humidity sensors when compared to unencapsulated devices. This sandwich tattoo capacitor (STC) platform exhibits an RH sensitivity up to 1000 pF/%RH and stability while mounted to living plant leaves over several days. Electrochemical impedance spectroscopy (EIS) validates the formation of electric double layers within the EtC films that encapsulate the printed electrodes providing tunable capacitance values based on the ionic concentration of the device transfer fluid.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Automated Microfluidic Platform for High-Throughput Biosensor Development 用于高通量生物传感器开发的自动化微流控平台

Advanced Sensor Research Pub Date : 2025-01-23 DOI: 10.1002/adsr.202400116

Shitanshu Devrani, Daniel Tietze, Alesia A. Tietze

{"title":"Automated Microfluidic Platform for High-Throughput Biosensor Development","authors":"Shitanshu Devrani, Daniel Tietze, Alesia A. Tietze","doi":"10.1002/adsr.202400116","DOIUrl":"https://doi.org/10.1002/adsr.202400116","url":null,"abstract":"Biorecognition elements immobilized into nanopores have transformed point-of-care (POC) diagnostics by converting molecular interactions into electrical and fluorescent signals.This study introduces Bio-Sensei, a high-throughput screening (HTS) microfluidic platform based on nanopore biosensing. Integrating a robotic sampler, electrochemical, and fluorescence setup, Bio-Sensei operates as an Internet of Things (IoT) platform with integrated data analysis. The platform's utility is demonstrated on functionalized with an amino terminal Cu(II)- and Ni(II)-binding (ATCUN) peptide ion track-etched membrane. Automated testing achieves a significantly higher F-stat value than the critical threshold, while unsupervised clustering reveals optimal nanopores pore size. The biosensor demonstrates remarkable stability, selectivity, and sensitivity with detection limits of 10−6 using fluorescence and 10−15 M using cyclic voltammetry measurements. Combining these methods enhances machine learning models for Cu2+ concentration prediction, achieving receiver operating characteristic area under the curve values exceeding 95%.","PeriodicalId":100037,"journal":{"name":"Advanced Sensor Research","volume":"4 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/adsr.202400116","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143571200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0