Advanced Chinese Medicine最新文献

{"title":"An updated review on the phytochemistry and pharmacological activity of black cumin (Nigella sativa L.)","authors":"Raghvendra Pandey,&nbsp;Brijesh Pandey,&nbsp;Atul Bhargava","doi":"10.1002/acm4.33","DOIUrl":"https://doi.org/10.1002/acm4.33","url":null,"abstract":"<p>In this review, a comprehensive and systematic evaluation of the phytochemical constituents, traditional medicinal applications, current pharmacological research, toxicity, and nanobiotechnology of black cumin has been undertaken. An exhaustive database retrieval was conducted to collect scientific information about <i>Nigella sativa</i> L. from 1956 to 2025 using PubMed, Scopus, ISI Web of Science, SciFinder, and CABI. Search was carried out using the keywords “<i>Nigella sativa</i>,” “<i>Nigella</i> oil,” “Ethnobotany,” “Phytochemistry,” “Pharmacological activity,” “Toxicity,” and “Nanotechnology.” Several important phytochemicals are found in the seeds of <i>N</i>. <i>sativa</i> L., and many of which seem to have a good impact on human health and are put to important use in the Ayurvedic, Unani, and Siddha systems of medicine. Among the active compounds, thymoquinone is the most important, forming about 30%–48% of the oil fraction. Besides thymoquinone, a wide range of phytochemicals such as thymohydroquinone, dithymoquinone, <i>p</i>-cymene, sabinene, carvacrol, 4-terpineol, kaempferol (glucoside) <i>t</i>-anethol, longifolene (sesquiterpene), <i>α</i>-pinene, <i>α</i>-hederin (pentacyclic triterpene), and thymol have also been reported. Current research has provided scientific evidence for the traditional uses of black cumin, especially antioxidant, anti-inflammatory, antibacterial, antifungal, antiviral, anticancer, antidiabetic, neuroprotective, gastroprotective, and antiarthritic effects. The review provides an in-depth analysis of the phytochemistry, traditional uses as well as potential pharmacological properties of <i>N</i>. <i>sativa</i> L. Since the plant is being extensively investigated for its medicinal properties, this review provides valuable up-to-date information on the current research status and will act as a reference for future research and applications of this important medicinal plant.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"2 1","pages":"13-29"},"PeriodicalIF":0.0,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.33","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143698825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilizing data mining and network pharmacology to analyze the formulation rule and function of enhancing immunity of Acanthopanax Radix et Rhizoma-containing health products","authors":"Meiyue Li,&nbsp;Pei Ma,&nbsp;Xue Li,&nbsp;Lijia Xu,&nbsp;Lifeng Yue","doi":"10.1002/acm4.31","DOIUrl":"https://doi.org/10.1002/acm4.31","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aims to analyze the formulation rules of Ciwujia (<i>Acanthopanax Radix et Rhizoma</i>)-containing health products and investigate the potential mechanisms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>By searching the Ciwujia-containing health products from the special food information inquiry platform of the State Administration for Market Regulation and MedSciNet, the basic information, including efficacy, tropism of taste, dosage form, health function etc., was analyzed using R language software packages and Excel. The formulation rules and core drug combinations were analyzed using the Apriori algorithm of IBM SPSS Modeler 18.0. By searching TCMID and other databases and reviewing relevant literature, the chemical components and potential targets database of Ciwujia was constructed. The protein–protein interaction network was analyzed using R package, String database, and Cytoscape software to screen for key components and targets related to health functions. Gene ontology functional annotation and Kyoto encyclopedia of genes and genomes pathway enrichment analysis were performed. Finally, molecular docking was used to verify the binding affinity of core targets and key components.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 315 cases of Ciwujia-containing health products were collected. The major health functions were to relieve physical fatigue and immune enhancement. A total of 205 effective components and 775 targets related to Ciwujia were obtained. By intersecting the genes related to Ciwujia and immune enhancement, 212 key target genes were identified. Ciwujia has an effect on immune enhancement through signaling pathways such as C-type lectin receptor, toll-like receptor, and NOD-like receptor. Molecular docking results also indicated a spontaneous and stable binding between the key components of Ciwujia and the core targets.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Through data mining, network pharmacology, and molecular docking research, this study analyzed the relevant information of Ciwujia-containing health products, preliminarily revealing its potential targets and mechanism pathways of immune enhancement and providing a theoretical basis for the development of future health products.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"2 1","pages":"30-44"},"PeriodicalIF":0.0,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.31","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143698928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional Chinese medicine for the treatment of chronic inflammatory diseases: A review of inhibitors for NLRP3 inflammasome","authors":"Yucen Zou,&nbsp;Pei Ma,&nbsp;Bin Li,&nbsp;Jiushi Liu,&nbsp;Lifeng Yue,&nbsp;Bengang Zhang,&nbsp;Haitao Liu","doi":"10.1002/acm4.32","DOIUrl":"https://doi.org/10.1002/acm4.32","url":null,"abstract":"<p>The NLR family pyrin domain-containing 3 (NLRP3) inflammasome is a vital part of the innate immune response, whilst its aberrant activation drives the progression of several noncommunicable diseases. It induces caspase-1 activation and the downstream substrates involved with the processing and secretion of the pro-inflammatory cytokines IL-1β and IL-18 and TNF-α. Activation of this complex often involves the adapter ASC and upstream sensors including NLRP1, NLRP3, NLRC4, AIM2, and pyrin, which are activated by different stimuli including infectious agents and changes in cell homeostasis, and play key roles in inflammation, development, and related cell death. However, the molecular mechanisms that integrate multiple inflammasome sensors to facilitate optimal host defense remain unknown; therefore, treatment is challenging. Natural medicine and small molecule-based therapies have been well-documented for their effectiveness in modulating inflammatory pathways and reestablishing the lost proteostasis inside the cells to combat several chronic diseases related to inflammation. Traditional Chinese medicines (TCMs) have potent clinical effects against NLRP3 inflammasome activation and could be used as complementary therapy. Therefore, this review summarizes various similar reports and highlights the important effects of nutraceuticals and bioactive compounds derived from medicinal plants on NLRP3 inflammasome activation and their possible mechanisms of action. Thus, TCM prescriptions, herbs, and bioactive compounds can be considered novel, practical, and accessible agents in chronic inflammatory diseases by inhibiting NLRP3 inflammasome activation.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"2 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.32","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143698819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatment of primary cutaneous CD30-positive anaplastic large cell lymphoma with Wenyang Shengji decoction and Huanglian ointment: A case report","authors":"Kai Li,&nbsp;Tingting Bao,&nbsp;Ruonan Wei,&nbsp;Yingying Yang,&nbsp;Mengjiao Kang,&nbsp;Wei Zhang,&nbsp;Xianyu Zeng,&nbsp;Yiqun Duan,&nbsp;Liuqing Chen,&nbsp;Linhua Zhao","doi":"10.1002/acm4.27","DOIUrl":"https://doi.org/10.1002/acm4.27","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <p>Primary cutaneous CD30 positive anaplastic large cell lymphoma (PC-ALCL) is a rare non-Hodgkin's lymphoma. Combined chemotherapy regimens such as CHOP (cyclophosphamide, doxorubicin, vincristine, and prednisone), MACOP-B (methotrexate, doxorubicin, cyclophosphamide, vincristine, prednisone, and bleomycin), or F-MACHOP (5-fluorouracil, methotrexate, cytosine-arabinoside, cyclophosphamide, doxorubicin, vincristine, and prednisone) are often used for its clinical treatment. In this study, we reported a new treatment method using a traditional Chinese therapy involving oral <i>Wenyang Shengji decoction</i> (WSD) combined with <i>Huanglian ointment</i> applied externally in a 32-year-old female patient with PC-ALCL. Introduction: A 32-year-old woman who complained of an ulcer on the forehead accompanied by significant pain. PC-ALCL was diagnosed by histopathological examination and immunohistochemical analysis. Treatment plan: WSD was prepared in 300 mL water and administered orally as a 150 mL decoction twice daily, and <i>Huanglian ointment</i> was applied to the ulcer three times daily. After 8 weeks of treatment with WSD combined with <i>Huanglian ointment</i>, the lesion healed completely. Immunohistochemical analysis revealed the presence of scattered CD3+++, CD4++, CD8++, CD20++, and CD30-positive cells. After 12 weeks of treatment, the ulcer healed completely, leaving only a marked pale red-pitted scar. The patient was followed up for 3 years without recurrence and no adverse events. Conclusion: oral WSD combined with <i>Huanglian ointment</i> applied to the ulcer for PC-ALCL can promote the healing of ulcers, reduce or alleviate the formation of scar, and eliminate CD30-positive cells. This case report provides a reference for the clinical treatment of PC-ALCL using traditional Chinese medicine.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 3","pages":"172-178"},"PeriodicalIF":0.0,"publicationDate":"2024-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.27","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancements in the application of cardiopulmonary exercise testing for overweight and obese populations","authors":"Tingshuai Fu,&nbsp;Mingzhong Xiao,&nbsp;Jiajia Ding,&nbsp;Chenxia Lu,&nbsp;Peiran Wang,&nbsp;Jingjing Yang,&nbsp;Qing Zhang","doi":"10.1002/acm4.26","DOIUrl":"https://doi.org/10.1002/acm4.26","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate the advancements in cardiopulmonary exercise testing (CPET) among overweight or obese patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Reviewed the recent studies on clinical trials of CPET in overweight and obese patients, thought about the CPET advantage in obesity, while CPET equipment use for elucidating the principles underlying obesity and using CPET kinematic scheme to explore fat metabolism.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The exercise program developed by CPET is scientific, sustainable and advantageous. With this trial, we can develop a relatively effective, fast and measurable amount of exercise, on the basis of the exercise test in obese people, CPET can provide scientific and digital motion reducing weight for overweight patients. At the same time, the trial has become widely applied in research into drug and surgical treatments for overweight patients. It is possible to quantify the efficacy of a trial and ultimately assess the merits of CPET.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>CPET is considered as a fundamental criterion for designing motion schemes. Despite limitations of equipment errors and patient endurance, the benefits of CPET in program formulation have been gradually recognized, which made it a promising tool in the field of obesity management.</p>\u0000 </section>\u0000 </div>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 3","pages":"162-171"},"PeriodicalIF":0.0,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.26","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Updates of surgical treatment in hemorrhoidal disease","authors":"Jianan Li,&nbsp;Huangfu Ma,&nbsp;Yue Wang,&nbsp;Lixia Lai,&nbsp;Xuecheng Zhang,&nbsp;Yanmei Wang","doi":"10.1002/acm4.25","DOIUrl":"https://doi.org/10.1002/acm4.25","url":null,"abstract":"<p>Hemorrhoidal disease is one of the most prevalent and frequently occurring conditions worldwide. Treatment modalities for hemorrhoids are multifaceted and tailored according to the severity of the condition. Various surgical procedures and modified approaches had been invented since 1937. Here we review the workflow, advantages, and disadvantages of different types of hemorrhoid surgery (conventional excisional hemorrhoidectomy, modified excisional surgery, stapled/partial stapled hemorrhoidopexy, and Doppler-guided hemorrhoidal artery ligation). There is no single treatment that fits all hemorrhoid patients. Surgeons should make the operation plan based on patients' conditions and wills.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 3","pages":"156-161"},"PeriodicalIF":0.0,"publicationDate":"2024-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.25","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert consensus on quality control indicators for integrative medicine in ankylosing spondylitis (2023 version)","authors":"Qingwen Tao,&nbsp;Liubo Zhang,&nbsp;Zeran Yan,&nbsp;Weiping Kong,&nbsp;Yuan Xu,&nbsp;Nan Zhang","doi":"10.1002/acm4.24","DOIUrl":"https://doi.org/10.1002/acm4.24","url":null,"abstract":"<p>The integrated treatment with Chinese and Western medicine plays an important role in the treatment of ankylosing spondylitis (AS), which can significantly relieve the patient's symptoms and improve quality of life. However, as a result of the lack of standardization of clinical management in some regions, the quality of AS treatment in China remains unoptimistic. In 2021, initiated by the Center for Integrative Medicine of China-Japan Friendship Hospital, led by the traditional Chinese medicine department of rheumatology of China-Japan Friendship Hospital, relying on the rheumatology branch of the Beijing Association of the integrating of traditional and Western medicine, and using the Delphi method, an expert consensus on “Quality Control Indicators for Integrative Medicine in Ankylosing Spondylitis” was established (Beijing Association of the Integrating of Traditional and Western Medicine Standardization Expert Consensus Filing Number: 2021Z031A2). The consensus revision updates the 2021 version by adding four items, which will provide a reference for the quality control of integrated traditional Chinese and Western medicine for AS in China and help improve the current diagnosis and treatment status of AS.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 3","pages":"149-155"},"PeriodicalIF":0.0,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.24","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142714678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical application of traditional Chinese medicine in the treatment of neuroendocrine neoplasms","authors":"Ying-Ying Chen,&nbsp;Shao-Bo Hu,&nbsp;Fei Su,&nbsp;Fu-Huan Yu,&nbsp;Ru-Ao Chen,&nbsp;Zi-Xuan Cheng,&nbsp;Huang-Ying Tan","doi":"10.1002/acm4.23","DOIUrl":"10.1002/acm4.23","url":null,"abstract":"<p>Neuroendocrine neoplasms (NENs) are a group of rare tumors with strong heterogeneity. Among these tumors, well-differentiated tumors can have a relatively good survival prognosis, while some tumors can have strong malignant potential and lead to increased mortality. Traditional Chinese medicine (TCM), which has a long history of thousands of years, has been widely used to treat tumors due to its unique advantages, such as economy, efficacy and few side effects. In recent years, the role of TCM in the treatment of NENs has gradually emerged. It can not only help prevent tumor recurrence and reduce the side effects of radiotherapy and chemotherapy but also relieve symptoms and improve quality of life. Various clinical studies have indicated that TCM has achieved good curative effects at different stages of treatment. We summarized the last 10 years of research progress on the clinical application of TCM in the treatment of NENs from four points of entry, aiming to provide a reference for the treatment of NENs.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 3","pages":"144-148"},"PeriodicalIF":0.0,"publicationDate":"2024-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.23","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141832080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Expert consensus on quality control indicators for integrative medicine in rheumatoid arthritis (2023 version)","authors":"Qingwen Tao,&nbsp;Jinping Wang,&nbsp;Zihan Wang,&nbsp;Yuan Xu,&nbsp;Jianming Wang,&nbsp;Yingze Zhang","doi":"10.1002/acm4.13","DOIUrl":"https://doi.org/10.1002/acm4.13","url":null,"abstract":"<p>The rising costs of cancer care and subsequent medical financial hardship for cancer survivors and families are well documented in the United States. Less attention has been paid to employment disruptions and loss of household income after a cancer diagnosis and during treatment, potentially resulting in lasting financial hardship, particularly for working-age adults not yet age-eligible for Medicare coverage and their families. In this article, the authors use a composite patient case to illustrate the adverse consequences of cancer diagnosis and treatment for employment, health insurance coverage, household income, and other aspects of financial hardship. They summarize existing research and provide nationally representative estimates of multiple aspects of financial hardship and health insurance coverage, benefit design, and employee benefits, such as paid sick leave, among working-age adults with a history of cancer and compare them with estimates among working-age adults without a history of cancer from the most recently available years of the National Health Interview Survey (2019–2021). Then, the authors identify opportunities for addressing employment and health insurance coverage challenges at multiple levels, including federal, state, and local policies; employers; cancer care delivery organizations; and nonprofit organizations. These efforts, when informed by research to identify best practices, can potentially help mitigate the financial hardship associated with cancer.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 2","pages":"79-86"},"PeriodicalIF":0.0,"publicationDate":"2024-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.13","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141624334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative therapy of traditional Chinese medicine and conventional medicine in the treatment of lupus nephritis from a single-center experience","authors":"Ruihua Liu,&nbsp;Xiao Yang,&nbsp;Jianwen Yu,&nbsp;Qiong Wen,&nbsp;Xueqing Yu,&nbsp;Wei Chen","doi":"10.1002/acm4.22","DOIUrl":"10.1002/acm4.22","url":null,"abstract":"<p>Lupus nephritis (LN) is the most common complication of systemic lupus erythematosus and the leading cause of mortality. The complex pathogenesis and various clinical manifestations of this disease increase the difficulty of the treatments. The current treatments with Western medicine including glucocorticoids, mycophenolate mofetil and other immunosuppressants, and biological agents have greatly improved the patients' survival. However, frequent recurrence occurred and LN remained an important cause of end stage renal disease. The increasing adverse effects with the prolongation of treatment also restrained the efficacy of Western medicine. Increasing evidence has demonstrated the therapeutic efficacy of traditional Chinese medicine (TCM) which provides a theoretical basis for the integrative therapy of TCM and Western medicine for LN. We previously established a unique comprehensive treatment strategy for LN with the combination of TCM and Western medicine based on the TCM theory and achieved good clinical efficacy. This review will summarize the single-center experience that integrative therapy of TCM, represented by Lupus Recipe and artesunate, and Western medicine for LN treatment, and elucidate the potential mechanism, with the purpose to provide reliable evidence for developing more effective personalized treatment strategies in the future.</p>","PeriodicalId":100029,"journal":{"name":"Advanced Chinese Medicine","volume":"1 3","pages":"137-143"},"PeriodicalIF":0.0,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/acm4.22","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141671134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}