Elsevier最新文献

{"title":"Fluorination of Fe, Sn, N atoms doped carbon enables the balance of activity and stability for oxygen reduction.","authors":"Yimin Chen, Jiayi Niu, Chaozhong Guo, Chenyang Shu, Jianglin Chen, Jinyan Wu, Rong Jin, Yao Liu, Hao Wang, Yujun Si, Xiaoyu Dong","doi":"10.1016/j.jcis.2025.138619","DOIUrl":"10.1016/j.jcis.2025.138619","url":null,"abstract":"<p><p>The development of highly active and durable carbon-based electrocatalysts for the oxygen reduction reaction (ORR) is of critical importance. In this study, a heteroatom-doped carbon catalyst (FeSn-NFC) was synthesized through the chelation of Fe³⁺ and dopamine hydrochloride, followed by Sn/F co-doping and carbonization. The resulting FeSn-NFC catalyst exhibits an ultrahigh specific surface area of 2387.9 m² g^-1, with micropores accounting for 79 % of its structure. The incorporation of Sn enhances the pyridinic nitrogen content and facilitates the elimination of reactive oxygen species (ROS). Electrochemical evaluations reveal exceptional ORR performance, with a half-wave potential (E_1/2) of 0.857 V and a minimal degradation (ΔE_1/2 = 11 mV) after accelerated aging tests. When integrated into a zinc-air battery, the FeSn-NFC catalyst delivers a peak power density of 217 mW cm^-2 and an energy density of 880 Wh kg^-1 (Zn), maintaining 93.2 % of its initial energy density after ∼115 h of continuous operation. This work offers a novel strategy for fabricating efficient, stable, and cost-effective ORR electrocatalysts, advancing the field of energy conversion technologies.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138619"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144797784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction of S-scheme Sb₂O₃/g-C₃N₄ heterojunctions for photocatalytic CO₂ and Cr(VI) reduction.","authors":"Penghui Yang, Jiaqi Yang, Xinyu Zen, Yuyang Gong, Junbo Zhong","doi":"10.1016/j.jcis.2025.138648","DOIUrl":"10.1016/j.jcis.2025.138648","url":null,"abstract":"<p><p>Photocatalytic CO₂ reduction is a promising strategy to address excessive CO₂ emissions. g-C₃N₄ photocatalyst has attracted widespread attention due to its appropriate bandgap and low toxicity. However, the rapid recombination of electron-hole pairs and the limited number of active sites severely restrict its practical application. In this study, we reported S-scheme Sb₂O₃/g-C₃N₄ heterojunctions. Introducing Sb₂O₃ onto g-C₃N₄ enhances active sites and adsorption capacity, and improves photogenerated carriers separation efficiency via heterojunction formation. Under simulated solar light irradiation, the Sb₂O₃/g-C₃N₄ heterojunctions exhibits superior photocatalytic CO₂ reduction performance relative to the reference Sb₂O₃ and g-C₃N₄. In-situ X-ray photoelectron spectroscopy (In-situ XPS), surface photovoltage spectroscopy (SPS), electron paramagnetic resonance (EPR) and ultraviolet photoelectron spectroscopy (UPS) further reveal the electron transfer mechanism in heterojunctions. In-situ diffuse reflectance Fourier transform infrared (DRIFTS) spectroscopy provides insight into the dynamic behavior of CO₂ into CO and CH₄. This work offers a feasible strategy for developing high-performance g-C₃N₄ photocatalysts to address environmental challenges.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138648"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144811471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revealing the dynamic arrangement mechanism of SiCw under combined AC-DC electric fields for composite performance enhancement: Modeling, analysis, and experiments.","authors":"Huanmin Yao, Haibao Mu, Maoqun Shen, Wenrui Tian, Wendong Li, Daning Zhang, Haoxiang Zhao, Andrea Cavallini, Guanjun Zhang","doi":"10.1016/j.jcis.2025.138632","DOIUrl":"10.1016/j.jcis.2025.138632","url":null,"abstract":"<p><p>Employing electric fields to induce directional arrangement of one-dimensional nanofillers within specific regions is a powerful strategy for enhancing the performance of composites. However, conventional single-mode electric fields (AC or DC) exhibit inherent \"orientation-distribution\" contradiction. Specifically, AC fields are effective for orientation but lack spatial control, while DC fields promote filler enrichment but fail to optimize orientation state. This study presents an innovative approach by establishing a theoretical framework that integrates both AC and DC electric fields along with a corresponding microscale dynamic model. This approach enables the precise and flexible manipulation of complex filler arrangements, thereby expanding opportunities for advanced material design. The model refines classical dielectrophoresis theory, incorporating interfacial charge and local electric field effects, elucidating the dynamic mechanisms of fillers under combined AC-DC electric fields. Numerical simulations reveal that AC fields primarily control orientation through dielectrophoresis, while DC fields regulate spatial distribution via electrophoresis. The synergistic combination of these two electric fields yields a pronounced \"orientation-enrichment\" effect, enabling the controlled and orderly arrangement of fillers within targeted areas. Moreover, high-aspect-ratio fillers promote chain formation but restrict rotation and migration, and frequencies above 1 kHz suppress alignment and interparticle attraction. Preliminary material design and preparation for enhanced electrical properties of renewable energy transmission device further indicate that this method is effective and flexible for complex application scenarios. This work advances our understanding of complex filler behavior in hybrid electric fields and offers a novel strategy for designing high-performance composites, paving the way for future innovations in material design.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138632"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144820187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation and clinical application of an LC-MS/MS method designed to simultaneously measure seven second-line TB drugs and two metabolites in human lung tissue.","authors":"Katie Kriegler Foster, Anil Pooran, Marthinus van der Merwe, Sandra Castel, Anton Joubert, Edda Zangenberg, Keertan Dheda, Lubbe Wiesner","doi":"10.1016/j.jpba.2025.117093","DOIUrl":"10.1016/j.jpba.2025.117093","url":null,"abstract":"<p><p>We developed and validated a novel bioanalytical method for the simultaneous quantification of levofloxacin, linezolid, moxifloxacin, delamanid, bedaquiline, clofazimine, and pretomanid, along with the metabolites of delamanid (DM-6705) and bedaquiline (N-desmethyl-bedaquiline, M2), in human lung tissue samples. Following homogenization by bead beating and extraction by protein precipitation, the analytes were separated on an Agilent 1260 Infinity II HPLC system using a Poroshell 120 C18 EC (2.1 mm×50 mm, 2.7 µm) column with gradient elution, applying a mobile phase consisting of 0.1 % formic acid in water and 0.1 % formic acid in a mixture of acetonitrile and methanol. Detection and quantification of the analytes and their stable isotope labelled internal standards were performed on a Sciex API 5500 QTrap mass spectrometer using positive electrospray ionization and multiple reaction monitoring. Validation according to the guidelines of the FDA and EMA proved the method to be precise, accurate, and robust with no significant influence of matrix components. The application of the method to the analysis of clinical samples demonstrated the feasibility of quantifying the second-line anti-tuberculosis drugs in human lung tissue and the potential to provide insights into the drug distribution across the infection sites in the lung.</p>","PeriodicalId":16685,"journal":{"name":"Journal of pharmaceutical and biomedical analysis","volume":"266 ","pages":"117093"},"PeriodicalIF":3.1,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144812162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The single-particle dynamics of square platelets on an inner spherical surface.","authors":"Yue Shi, Fuzhou Liu, Yanran Li, Jianan Zhu, Mingcheng Yang, Kun Zhao, Yiwu Zong","doi":"10.1016/j.jcis.2025.138513","DOIUrl":"10.1016/j.jcis.2025.138513","url":null,"abstract":"<p><strong>Hypothesis: </strong>The diffusion of colloidal particles on curved surfaces is crucial for understanding mass transport in a wide range of biological and physical systems. To date, most experimental studies on colloid diffusion on curved surfaces have focused on the behavior of isotropic colloids diffusing on soft oil-water interfaces. However, there has been no experimental work reported on how anisotropic colloids diffuse on hard spherical surfaces.</p><p><strong>Experiments: </strong>Herein, we report a first experimental study of the single-particle dynamics of micro-sized Brownian square platelets on solid spherical surfaces with four different curvatures. Utilizing video microscopy and particle-tracking techniques, we investigated both the translational and rotational motion of the square platelets. An analytical model based on Smoluchowski equations was developed to explain the observed diffusion behaviors.</p><p><strong>Findings: </strong>The translational motion of the square platelets was found to be sub-diffusive at time scales comparable to their relaxation time, with the power-law exponent of the mean square displacement (MSD) decreasing as the curvature increased. In contrast, the rotational diffusion of the platelets exhibited minimal variation with changes in curvature. The developed analytical model based on Smoluchowski equations could explain the observations in both translational and rotational diffusion, highlighting the crucial role of surface geometry in determining the diffusion dynamics. This research provides new insights into the diffusion of anisotropic particles on hard spherical curved surfaces, which will pave the way for understanding mass transport problems on curved surfaces in various fields.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138513"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enrichment of γ-NiOOH in ultrathin metal-organic framework nanosheet arrays by linker engineering for urea-assisted natural seawater electrolysis.","authors":"Nguyen Duy Hai, Nhat Duy Tran, Thuy Tien Nguyen Tran, Jianmin Yu, Lishan Peng, Thi Anh Le, Phuong Dung Ngoc Tran, Nhu Hoa Thi Tran, Thang Bach Phan, Ngoc Quang Tran","doi":"10.1016/j.jcis.2025.138618","DOIUrl":"10.1016/j.jcis.2025.138618","url":null,"abstract":"<p><p>Metal-organic frameworks have been widely considered a potential alternative for noble metal catalysts for green hydrogen from seawater electrolysis, yet their performance is often limited by low activity and poor stability. Here, we propose a linker engineering strategy to optimize the phase composition of ultrathin Ni-MOF nanosheet arrays, aiming to enhance both activity and stability. We found that partial substitution of terephthalic acid (BDC) with electron-withdrawing tetrafluoroterephthalate (TFBDC) ligand alters the electronic structure and significantly promotes the formation of the catalytically active γ-NiOOH phase in Ni-TFBDC-2. This results in a 90 mV reduction in the overpotential for the oxygen evolution reaction at 50 mA cm^-2, surpassing the performance of a state-of-the-art RuO₂ catalyst, and is accompanied by an increased corrosion potential in seawater. Furthermore, the enrichment of the γ-NiOOH phase in Ni-TFBDC-2 effectively suppresses the passivation during urea oxidation reaction (UOR) in a seawater electrolyte, enabling the achievement of an industrially relevant current density of 0.8 A cm^-2. Operando characterizations reveal that Ni-TFBDC-2 undergoes an electrooxidation process to form Ni³⁺ species, which subsequently act as the active catalytic sites for the OER. Additionally, the urea-assisted natural seawater electrolyzer assembled with Ni-TFBDC-2 requires a low voltage of 1.76 V at 400 mA cm^-2 and demonstrates excellent durability over 170 h of continuous operation. This work offers a novel strategy to enrich the catalytically active phase in MOF-based electrocatalysts, aiming to achieve high activity and long-term stability during urea-assisted natural seawater electrolysis. It is noteworthy that different notable aspects, such as the durability of the materials after prolonged reaction, should be more thoroughly considered for practical applications on larger scales.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138618"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rapid detection of plasma exosomal LncRNA CASC9 for HCC using RT-RPA-CRISPR/Cas12a assay.","authors":"Jie Wu, Xi Li, Xiangbao Yin, Junwen Hu, Pengcheng Zhou, Xiaofeng Zhong, Mingming Wu","doi":"10.1016/j.jpba.2025.117085","DOIUrl":"10.1016/j.jpba.2025.117085","url":null,"abstract":"<p><p>Hepatocellular carcinoma (HCC) is a leading cause of cancer-related mortality worldwide. Early detection is essential for improving patient outcomes. Long non-coding RNAs (lncRNAs) in plasma exosomes have emerged as promising non-invasive biomarkers. However, sensitive detection methods remain limited. Plasma exosomes were isolated and validated using transmission electron microscopy (TEM), nanoparticle tracking analysis (NTA), and Western blot (WB). RNA sequencing identified CASC9 as the most significantly upregulated exosomal lncRNA in HCC patients. Its diagnostic value was evaluated using real-time quantitative PCR (RT-qPCR) and a novel RT-RPA-CRISPR/Cas12a fluorescence assay. Diagnostic performance was assessed through receiver operating characteristic (ROC) curve analysis and compared with alpha-fetoprotein (AFP). Exosomal CASC9 levels were significantly elevated in HCC patients and correlated with tumor size, stage, and number (P < 0.001). ROC analysis demonstrated that CASC9 had superior diagnostic accuracy (area under the curve [AUC] = 0.822) compared to AFP (AUC = 0.795), with further improvement when combined (AUC = 0.875). The RT-RPA-CRISPR/Cas12a assay achieved a detection limit of 0.1 copies/μL, outperforming RT-qPCR. When combined with RT-qPCR and AFP, the method achieved an AUC of 0.987 against normal controls and 0.975 against benign cases. Plasma exosomal CASC9 is a promising diagnostic biomarker for HCC. The RT-RPA-CRISPR/Cas12a assay offers a rapid, ultra-sensitive, and clinically feasible detection strategy.</p>","PeriodicalId":16685,"journal":{"name":"Journal of pharmaceutical and biomedical analysis","volume":"266 ","pages":"117085"},"PeriodicalIF":3.1,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assembling graphene quantum dots on NiFe-LDH provokes ligand effect for electrocatalytic oxygen evolution reaction at industrial-level current density.","authors":"Longcheng Xu, Sheng Qian, Jingying Wei, Tengfei Jiang, Hua Zhang, Jingqi Tian","doi":"10.1016/j.jcis.2025.138659","DOIUrl":"10.1016/j.jcis.2025.138659","url":null,"abstract":"<p><p>Electrocatalytic oxygen evolution reaction (OER) plays a key role in water splitting owing to the kinetically more difficult multi-electron transfer process, but the performance is still limited at industrial scale ampere-level current densities. Herein, we develop a surface modification strategy to assemble amino-functionalized graphene quantum dots on NiFe LDH (NiFe LDH/NGQDs) via the coordination between metallic centers with the amino groups in NGQDs. As a nanosized ligand, surface-assembled NGQDs feature sp² conjugation to induce electron redistribution in the coordinated metallic centers, which optimizes OO coupling as a rate-determining step (RDS) in OER. Moreover, edge-aligned NGQDs electrostatically repel from each other to enlarge the interlayered space, allowing abundant OH^- diffusion to facilitate OER kinetics. Such NiFe LDH/NGQDs exhibit an outstanding OER performance with an overpotential of 336mV to achieve a current density of 1.0 A cm^-2 with long-term stability. This work proposes a surface assembly-based catalyst design concept to achieve industrial-level current density in water splitting.</p>","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138659"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144815487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Batchwise data analysis with inter-batch feature alignment in large scale platelet lipidomics study using UHPLC-ESI-QTOF-MS/MS by data-independent SWATH acquisition.","authors":"Kristina Dittrich, Xiaoqing Fu, Adrian Brun, Madhumita Chatterjee, Meinrad Gawaz, Michael Lämmerhofer","doi":"10.1016/j.jpba.2025.117088","DOIUrl":"10.1016/j.jpba.2025.117088","url":null,"abstract":"<p><p>Untargeted lipidomics by ultra-high-performance liquid chromatography (UHPLC) hyphenated with tandem mass spectrometry using data-independent acquisition (DIA) is a technique with increasing popularity for generating new hypotheses in support of clinical research. Its strength is its data comprehensiveness on both MS and MS/MS level. However, especially when applying SWATH acquisition for large-scale analysis, e.g. clinical studies with over 1000 s to 10,000 s of samples, simultaneous processing of acquired data in multiple batches over longer period of time may be challenging due to retention time and mass shifts as well as huge bulk of data, particularly when computer power is limited. This problem can be alleviated by a batchwise data processing strategy by inter-batch feature alignment of separately processed sample batches. After batchwise automated data processing in MS-DIAL, feature lists can be combined by aligning identical features from different batches attributed to similarity in precursor m/z and retention time, with the intention to generate a representative reference peak list for targeted data extraction. The workflow was established with detected features from three batches of platelet lipid extracts of coronary artery disease (CAD) patients (n = 120) and then applied on a clinical cohort with 1057 CAD patients measured in 22 batches. As a result, the lipidome coverage was significantly increased when several batches were used to create the target feature list compared to a single batch and the increase of annotated features levelled off with 7-8 batches. Further, the lipid identification was improved in terms of number of structurally annotated features.</p>","PeriodicalId":16685,"journal":{"name":"Journal of pharmaceutical and biomedical analysis","volume":"266 ","pages":"117088"},"PeriodicalIF":3.1,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Redox homeostasis disruptors enhanced cuproptosis effect for synergistic photothermal/chemodynamic therapy\" [J. Colloid. Interface Sci. 678 (2025) 1060-1074].","authors":"Zhen Liu, Junhong Ling, Nan Wang, Xiao-Kun Ouyang","doi":"10.1016/j.jcis.2025.138608","DOIUrl":"10.1016/j.jcis.2025.138608","url":null,"abstract":"","PeriodicalId":351,"journal":{"name":"Journal of Colloid and Interface Science","volume":"700 Pt 3","pages":"138608"},"PeriodicalIF":9.7,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}