Yuhang Lin, Ruishuang Yuan, Tianshuo Wang, Yuanhao Liu, Lianxi Pu, Mingxuan Jia, Xilong Zhou, Min Zhang, Lijun Ding, Weiran Zhu, Kun Wang
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引用次数: 0
Abstract
Aflatoxin B1 (AFB1) is widely present in food crops and their products, posing significant risks to human health as a contaminant. Therefore, developing reliable, rapid, and convenient detection methods for AFB1 is crucial to ensure food safety. In this study, a MOF-on-MOF strategy was employed to prepare bimetallic MOF, using MIL-101 (Fe) as the host metal-organic framework (MOF) and MIL-125 (Ti), which exhibits excellent peroxidase-like activity and photosensitivity, as the guest. The material was then calcined under a nitrogen atmosphere to promote the carbonization of the framework and the development of a hollow structure, resulting in the fabrication of MIL-125@MIL-101-N2 catalyst. This method utilizes the distinct properties of iron and titanium to lower the reaction barriers in the colorimetric process. The host-guest interaction in the MOF-on-MOF structure prevents the excessive coordination of Fe, which would speed up the recombination of photogenerated electron-hole pairs, thereby broadening the light absorption range and boosting the photogenerated electron capability. Based on the bimetallic MOF-on-MOF strategy, a colorimetric sensor was constructed with MIL-125@MIL-101-N2 material and aptamer as recognition element for detection of AFB1. The results demonstrated a linear relationship between the RGB values and AFB1 concentrations in the range of 1-1380 ng/mL, which can be used for sensitive and visual detection of AFB1.
期刊介绍：
Talanta provides a forum for the publication of original research papers, short communications, and critical reviews in all branches of pure and applied analytical chemistry. Papers are evaluated based on established guidelines, including the fundamental nature of the study, scientific novelty, substantial improvement or advantage over existing technology or methods, and demonstrated analytical applicability. Original research papers on fundamental studies, and on novel sensor and instrumentation developments, are encouraged. Novel or improved applications in areas such as clinical and biological chemistry, environmental analysis, geochemistry, materials science and engineering, and analytical platforms for omics development are welcome.
Analytical performance of methods should be determined, including interference and matrix effects, and methods should be validated by comparison with a standard method, or analysis of a certified reference material. Simple spiking recoveries may not be sufficient. The developed method should especially comprise information on selectivity, sensitivity, detection limits, accuracy, and reliability. However, applying official validation or robustness studies to a routine method or technique does not necessarily constitute novelty. Proper statistical treatment of the data should be provided. Relevant literature should be cited, including related publications by the authors, and authors should discuss how their proposed methodology compares with previously reported methods.
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