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Asymmetric Intramolecular O-Hydroximation of Alkynes 炔烃的不对称分子内 O-羟肟化反应
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-27 DOI: 10.31635/ccschem.024.202404296
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引用次数: 0
Cu-Catalyzed Asymmetric Hydrogermylation Towards C- and Ge-Stereogenic Germanes 铜催化不对称氢锗化作用生成 C 和 Ge-Stereogenic Germanes
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-27 DOI: 10.31635/ccschem.024.202404335
{"title":"Cu-Catalyzed Asymmetric Hydrogermylation Towards C- and Ge-Stereogenic Germanes","authors":"","doi":"10.31635/ccschem.024.202404335","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404335","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"87 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141462378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Radical Solution to Nucleophilic Substitution: Photocatalyzed Phosphinylation of Alkyl Halides at Room Temperature 亲核置换的激进解决方案：室温下烷基卤化物的光催化膦化反应
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-27 DOI: 10.31635/ccschem.024.202404368
{"title":"A Radical Solution to Nucleophilic Substitution: Photocatalyzed Phosphinylation of Alkyl Halides at Room Temperature","authors":"","doi":"10.31635/ccschem.024.202404368","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404368","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"27 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141462651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Supramolecular Bifunctional Hydrogel with Zero-Order Release Kinetics to Resist Bacterial Infection and Foreign Body Response of Implants 具有零阶释放动力学的超分子双功能水凝胶可抵抗植入物的细菌感染和异物反应
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-26 DOI: 10.31635/ccschem.024.202404276
Sijia Chen, Lin Li, Yunqing Gu, Fang Luo, Kunyu Chen, Yan Lou, Quan Huang, Jingjing Hu, Yiyun Cheng
{"title":"A Supramolecular Bifunctional Hydrogel with Zero-Order Release Kinetics to Resist Bacterial Infection and Foreign Body Response of Implants","authors":"Sijia Chen, Lin Li, Yunqing Gu, Fang Luo, Kunyu Chen, Yan Lou, Quan Huang, Jingjing Hu, Yiyun Cheng","doi":"10.31635/ccschem.024.202404276","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404276","url":null,"abstract":"<p>Supramolecular hydrogels demonstrate considerable potential in drug delivery owing to their distinctive features, including bio-adhesiveness, self-healing behaviors, biodegradability, and biocompatibility. Nevertheless, the fabrication of supramolecular hydrogels utilizing exclusively clinically approved drugs remain challenging, typically necessitating chemical modifications of the drugs to facilitate the gelation process. In this study, we report a novel type of supramolecular hydrogel through the direct assembly of two clinically approved drugs, tobramycin and mycophenolic acid, via combined electrostatic and hydrophobic interactions. The hydrogel shows adjustable bio-adhesiveness, zero-order release kinetics, good biocompatibility, and maintained antibacterial and immunosuppressive activities. It efficiently inhibits bacterial infections and foreign body responses, and accelerates tissue healing in several subcutaneous/intraosseous implantation models accompanied by bacteria infections. This work provides a facile and promising strategy to fabricate supramolecular hydrogels with stable drug release kinetics using clinically approved drugs.</p>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"32 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142198475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cobalt-Catalyzed Asymmetric Synthesis of Planar Chiral Ferrocene Derivatives via C(sp2)–C(sp3) Bond Formation 通过 C（sp2）-C（sp3）键形成钴催化不对称合成平面手性二茂铁衍生物
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-25 DOI: 10.31635/ccschem.024.202404231
{"title":"Cobalt-Catalyzed Asymmetric Synthesis of Planar Chiral Ferrocene Derivatives via C(sp2)–C(sp3) Bond Formation","authors":"","doi":"10.31635/ccschem.024.202404231","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404231","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"10 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141453172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Amyloid-Like Protein Coating as a Barrier Against Plasticizer Leaching 淀粉样蛋白涂层是防止增塑剂浸出的屏障
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-12 DOI: 10.31635/ccschem.024.202404046
{"title":"Amyloid-Like Protein Coating as a Barrier Against Plasticizer Leaching","authors":"","doi":"10.31635/ccschem.024.202404046","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404046","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"28 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141315651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Author Spotlight 作者聚焦
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-06-03 DOI: 10.31635/ccschem.024.202400510ed2
{"title":"Author Spotlight","authors":"","doi":"10.31635/ccschem.024.202400510ed2","DOIUrl":"https://doi.org/10.31635/ccschem.024.202400510ed2","url":null,"abstract":"CCS Chemistry, Volume 6, Issue 6, Page 1356-1359, June 2024.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"43 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141246327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-Mode Reversible Imaging of the Hypoxia Status of Acute and Chronic Hepatic Injury 急性和慢性肝损伤缺氧状态的双模式可逆成像
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-05-29 DOI: 10.31635/ccschem.024.202404092
{"title":"Dual-Mode Reversible Imaging of the Hypoxia Status of Acute and Chronic Hepatic Injury","authors":"","doi":"10.31635/ccschem.024.202404092","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404092","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"28 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141182669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Poly(N-Heterocyclic Carbene)-Derived Organometallic Cylinders and Barrels 聚(N-杂环羰基)衍生有机金属圆筒和圆桶
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-05-23 DOI: 10.31635/ccschem.024.202404269
{"title":"Poly(N-Heterocyclic Carbene)-Derived Organometallic Cylinders and Barrels","authors":"","doi":"10.31635/ccschem.024.202404269","DOIUrl":"https://doi.org/10.31635/ccschem.024.202404269","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"213 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141092016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Porous Nanocarbons with Polynuclear Aromatic Cores 具有多核芳香族内核的多孔纳米碳化物
IF 11.2 1区 化学
CCS Chemistry Pub Date : 2024-05-21 DOI: 10.31635/ccschem.024.202403889
{"title":"The Porous Nanocarbons with Polynuclear Aromatic Cores","authors":"","doi":"10.31635/ccschem.024.202403889","DOIUrl":"https://doi.org/10.31635/ccschem.024.202403889","url":null,"abstract":"CCS Chemistry, Ahead of Print.<br/>","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"32 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2024-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141079322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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