CCS Chemistry最新文献

{"title":"Ligand-Directed, Palladium-Catalyzed Chemo- and Regiodivergent Ring-Opening/Cross-Coupling Reactions of gem-Difluorocyclopropanes with Enamides","authors":"Wenhao Liu, Charlotte V. Purcell, Annika S. Waples, Junqi Su, Leiyang Lv, Shuming Chen, Chao-Jun Li","doi":"10.31635/ccschem.026.202607846","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607846","url":null,"abstract":"Divergent synthesis of functionalized molecules from the same starting materials represents a challenging yet highly appealing goal in modern synthetic chemistry. Herein, we disclose a ligand-controlled, Pd-catalyzed chemo- and regiodivergent ring-opening/cross-coupling reaction of <i>gem</i>-difluorocyclopropanes with enamides. This transformation achieved the unique C–N coupling to afford fluorinated enamides when bis(diphenylphosphino)ethane (EPhos) was used as the ligand, while the highly electron-rich, bis(1-adamantyl)-butylphosphane) (cataCXium) A delivered C–C coupling via 3,3′-reductive elimination exclusively, which was followed by intramolecular annulation to afford nonsymmetrical trisubstituted <i>N</i>–H pyrrole derivatives. This divergent protocol exhibited a broad substrate scope and good functional group tolerance, with its synthetic utility demonstrated <i>via</i> diversified downstream derivatizations. Density functional theory (DFT) calculations shed light on the reaction mechanism, lending support to a switch between inner- and outer-sphere bond formations depending on the ligand employed.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"451 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148595744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formal Aldehyde Insertion into C-S Bonds of Sulfones Enables Modular Synthesis of Tetrasubstituted gem-Bis(trifluoromethyl) Alkenes","authors":"Feng Zhao, Kaidi Zhu, Yunlong Zhao, Lin Xiao, Fu Chen, Yu He, Xiu Wang, Mingyou Hu, Chuanfa Ni, Jinbo Hu","doi":"10.31635/ccschem.026.202608038","DOIUrl":"https://doi.org/10.31635/ccschem.026.202608038","url":null,"abstract":"Nucleophile-triggered activation of fluoroalkyl sulfones offers a potential entry to fluorinated building blocks, yet formal carbonyl insertion into C-S bonds of sulfones remains largely unexplored due to stringent structural and electronic constraints. Herein, we report that heptafluoroisopropyl 2-pyridyl sulfone (HFIPS) uniquely enables efficient formal insertion of aldehyde into C-S bonds of sulfones under mild fluoride catalysis. Mechanistic investigations, supported by stoichiometric experiments and DFT analysis, identify the nucleophilic addition to aldehyde as the rate-determining step and establish HFIPS as the predominant sulfonylating species under turnover conditions. The resulting sulfonate intermediates are converted through a mechanistically indispensable bromination-elimination sequence, providing streamlined access to tetrasubstituted bromo-<i>gem</i>-bis(trifluoromethyl) alkenes. The bromo substituent serves as a versatile handle for modular downstream functionalization. Structural and photophysical studies reveal that geminal CF₃ groups impose steric restriction and suppress intramolecular rotation, thus enhancing the aggregation-induced emission behavior in TPE-derived systems. This unified platform integrates formal C-S insertion chemistry with fluorinated alkene synthesis and functional materials design.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"4 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148582246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis of Abietane Dimers through Oxidative Coupling of p-quinones","authors":"Jinyang Liu, Yiming Ding, Tao Zhang, Tianle Chang, Peng Wang, Yin Yang, Jun Deng","doi":"10.31635/ccschem.026.202607988","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607988","url":null,"abstract":"Oxidative homo-coupling of phenols has been widely utilized in the synthesis of natural products and pharmaceuticals. In contrast, the direct oxidative homo-coupling of quinones has remained a longstanding challenge because of their electron-deficient character and intrinsic redox reactivity. Herein, we report a facile FeCl₃-catalyzed homo-coupling of <i>p</i>-quinones that provides direct access to highly oxidized biquinones without the need for prefunctionalized coupling partners. The reaction exhibits good functional-group tolerance and can be applied to a range of alkyl-, aryl-, and heteroaryl-substituted <i>p</i>-quinones. Preliminary mechanistic experiments, including radical inhibition studies, oxidant-dependence experiments, and EPR analysis, support the involvement of quinone-derived radical intermediates in the coupling process. Application of this method enabled the enantiospecific synthesis of grandidone D (<b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><b>4</b></b>), 7-<i>epi</i>-grandidone D (<b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><b>9</b></b>), and the proposed structure of 7,7′-bistaxodione (<b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"><b>10</b></b>) through a late-stage dimerization strategy from commercially available dehydroabietic acid.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"39 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148552186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficient, versatile and sustainable electrocatalytic valorization of biomass-derived feedstocks via coupling with alcohols under ambient conditions","authors":"Miao Wang, Shuaikang Yang, Xinrui Tang, Pengbo Zhang, Huaizhu Wang, Fu Liu, Mingzheng Shao, Yuecheng Xiong, Fangren Qian, Fengkun Hao, Liang Guo, Guozhi Wang, Xiang Meng, Yunhao Wang, Juan Wang, Hanxiao Du, Chaohui Wang, Rundong Zhao, Tao Peng, Guoqiang Wang, Zhong Jin, Zhanxi Fan","doi":"10.31635/ccschem.026.202608130","DOIUrl":"https://doi.org/10.31635/ccschem.026.202608130","url":null,"abstract":"Oxygen-containing heterocyclic compounds hold significant importance in pharmaceuticals, biologics, cosmetics, and energy storage industry. However, developing innovative synthetic methods for strained O-heterocycles remains challenging. Unlike conventional thermo-catalytic methods that require harsh reaction conditions, the mild conditions of electrosynthesis route can mitigate the degradation of carbon skeletons in organic cyclic molecules. Herein, we report an efficient, sustainable, and atom-economical electrochemical oxidative coupling strategy for the synthesis of diverse, highly strained eight-membered O-heterocycles featuring significant transannular interactions. This approach utilizes biomass-derived monomers under ambient conditions. Mechanistic investigations highlight the essential role of Lewis acid mediation and hydrogen bonding in stabilizing key intermediate configurations. Moreover, by using methanol-d₄ with biomass-based hydrocinnamaldehyde, we realize high-yield electrosynthesis of a deuterated product. Scale-up experiments and techno-economic analysis further confirm the practical economic feasibility of acetal electrosynthesis route. This work not only establishes a versatile platform for constructing eight-membered heterocyclic systems, but also showcases the transformative capacity of electrocatalysis in addressing long-standing synthetic challenges associated with high-strain molecules.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"44 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148589038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A catalytic system with high activity, reaction rate and rapid degradation capability for 4-Chlorophenol","authors":"Siyi Chen, Xuchen Zheng, Han Wu, Yang Gao, Xinyu Ping, Siao Chen, Yurui Xue, Yuliang Li","doi":"10.31635/ccschem.026.202607840","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607840","url":null,"abstract":"We report a catalytic system combined physics and chemical effects in which independent molybdenum atoms successfully anchor on the surface of GDY, forming a complex functional system of Mo-CoO_x/GDY, and achieving precise control on the anchoring position and metal valence states. Comprehensive characterization reveals that the atomic Mo doping has caused significant tensile strain, lattice distortion and other physical effects in this system, as well as reversible dynamic effects of non-integer charge transfer between metal atoms and GDY. These effects generate the chemical and physical evolution of the catalytic system structure, resulting in continuous high activity, selectivity, and stability at the catalyst interface. The Mo-CoO_x/GDY catalyst exhibits a high-speed degradation effect in the removal of 4-chlorophenol (4-CP) to achieve complete degradation (100%) within 5 minutes. During this degradation process, the catalytic system of Mo-CoO_x/GDY demonstrates high intrinsic activity, extremely remarkable properties and performance with a value for TOF = 0.057 s⁻¹, mass activity = 56.9 mmol g^-1 min⁻¹ and fast kinetics (<i>k</i>_{<i>obs</i> =} 0.59 min⁻¹). This catalyst, as a new degradation mechanism, is significantly different from the traditional mechanism description. Its inherent characteristics are driven by these numerous effects, generating high concentrations of active •OH groups with high selectivity.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"261 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148538237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Singlet Excited State-Dominated Intracellular Unnatural Photocatalytic Reaction","authors":"Wen-Jin An, Jia-Yao Li, Yun-Xi Liu, Dong-Jie Hou, Zhen-Wei Li, Chen-Xu Pei, Qiu-Ting He, Yi Peng, Shun-Xian Yin, Dong-Xue Guo, Rui-Jie Cao, Yun-Rong Li, Le Zeng, Qing-Long Qiao, Dai-Wen Pang, Ling Huang","doi":"10.31635/ccschem.026.202607874","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607874","url":null,"abstract":"Intracellular unnatural photocatalysis has recently emerged as a promising approach for applications including proximity labeling and photobiocatalysis. However, most reported intracellular photocatalytic reactions rely on long-lived triplet excited states, whose sensitization often generates reactive oxygen species (ROS), causing irreversible photodamage and oxidative stress in cells. Herein, we report the use of perylene and its derivatives, which exhibit near-unity fluorescence quantum yields, as photocatalysts for the development of intracellular photocatalytic reactions mediated predominantly by singlet excited states. These compounds efficiently mediate the photoreduction of azides in various media, including organic solvents, cell culture media, and mammalian cells, enabling cascade formation of indole derivatives. Moreover, incorporation of an azide moiety into the perylene scaffold allows light irradiation alone to induce intramolecular azide reduction by the perylene unit, resulting in intramolecular cyclization and formation of a perylene-fused indole structure. Exploiting this transformation, we demonstrate photoactivatable super-resolution fluorescence imaging in living cells. This study establishes a singlet-state-mediated photocatalytic reaction for intracellular unnatural photocatalysis, providing a powerful tool for cellular manipulation with high spatiotemporal precision.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"20 2 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148552183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assembly and Encapsulation Properties of Cages Featuring Cofacial Porphyrins and N-Heterocyclic Carbene‒Metal Bonds","authors":"Jin-Ping Chang, Le Zhang, Chen Zou, F. Ekkehardt Hahn, Ying-Feng Han","doi":"10.31635/ccschem.026.202607676","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607676","url":null,"abstract":"The porphyrin H&lt;sub&gt;4&lt;/sub&gt;-&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"&gt;&lt;b&gt;1&lt;/b&gt;&lt;/b&gt;(PF&lt;sub&gt;6&lt;/sub&gt;)&lt;sub&gt;2&lt;/sub&gt; bearing 5,15-phenyl-10,20-{1,5-imidazo[1,5-&lt;i&gt;a&lt;/i&gt;]pyridinium} substituents has been reacted with Zn(OAc)&lt;sub&gt;2&lt;/sub&gt; to give the porphyrin complex [Zn(H&lt;sub&gt;2&lt;/sub&gt;-&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"&gt;&lt;b&gt;1&lt;/b&gt;&lt;/b&gt;)](PF&lt;sub&gt;6&lt;/sub&gt;)&lt;sub&gt;2&lt;/sub&gt;. The reaction of H&lt;sub&gt;4&lt;/sub&gt;-&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"&gt;&lt;b&gt;1&lt;/b&gt;&lt;/b&gt;(PF&lt;sub&gt;6&lt;/sub&gt;)&lt;sub&gt;2&lt;/sub&gt; with Ag&lt;sub&gt;2&lt;/sub&gt;O yielded the tetranuclear mixed-valence porphyrin/carbene cage-type assembly [Ag&lt;sup&gt;I&lt;/sup&gt;&lt;sub&gt;2&lt;/sub&gt;{Ag&lt;sup&gt;II&lt;/sup&gt;(&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"&gt;&lt;b&gt;1&lt;/b&gt;&lt;/b&gt;)}&lt;sub&gt;2&lt;/sub&gt;](PF&lt;sub&gt;6&lt;/sub&gt;)&lt;sub&gt;2&lt;/sub&gt;. The mononuclear Zn-porphyrin complex [Zn(H&lt;sub&gt;2&lt;/sub&gt;-&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"&gt;&lt;b&gt;1&lt;/b&gt;&lt;/b&gt;)](PF&lt;sub&gt;6&lt;/sub&gt;)&lt;sub&gt;2&lt;/sub&gt; also reacts with Ag&lt;sub&gt;2&lt;/sub&gt;O to give the cage-type heterobimetallic porphyrin/carbene assembly [Ag&lt;sup&gt;I&lt;/sup&gt;&lt;sub&gt;2&lt;/sub&gt;{Zn(&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.org/1999/xlink\"&gt;&lt;b&gt;1&lt;/b&gt;&lt;/b&gt;)}&lt;sub&gt;2&lt;/sub&gt;](PF&lt;sub&gt;6&lt;/sub&gt;)&lt;sub&gt;2&lt;/sub&gt;. Both doubly C&lt;sub&gt;NHC&lt;/sub&gt;‒Ag‒C&lt;sub&gt;NHC&lt;/sub&gt; bridged cages undergo transmetalation with [AuCl(THT)] to give the heterobimetallic assemblies [Au&lt;sup&gt;I&lt;/sup&gt;&lt;sub&gt;2&lt;/sub&gt;{Zn(&lt;b xmlns:bkstg=\"http://www.atypon.com/backstage-ns\" xmlns:fn=\"http://www.w3.org/2005/xpath-functions\" xmlns:pxje=\"java:com.atypon.frontend.services.impl.PassportXslJavaExtentions\" xmlns:urlutil=\"java:com.atypon.literatum.customization.UrlUtil\" xmlns:xlink=\"http://www.w3.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"37 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Upcycling of Epoxy Resins via An Oxidation–Cope Elimination Pathway Using Organic Solvent","authors":"Beitao Liu, Xiaotong Pan, Cijian Zhang, Leiming Sun, Lei Shi, Francisco Zaera, Xigao Jian, Zhihuan Weng","doi":"10.31635/ccschem.026.202607659","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607659","url":null,"abstract":"The strong cross-linked network structure of fiber-reinforced epoxy composites gives them excellent mechanical properties but also makes them difficult to recycle after disposal. Expensive catalysts or undesirable oxidants are often required to degrade such stable material. In this work, we report a DMSO-dissolution method that can recycle amine-cured epoxy resins as well as commercial composites using dimethyl sulfoxide in air. By selectively breaking C–N bonds via an oxidation-Cope elimination mechanism, fiber recovery and resin matrix upcycling can be achieved. A high products mass recovery (&gt;98%) can be attained from the degradation of resin matrices, which can be used as wood adhesives with adhesive strength comparable to commercial glues. Our results can be easily extended to degradation of other polymers with tertiary amine structures, incentivizing a circular economy for waste plastics.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"255 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148459873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pressure-Induced Lattice Strain Boosting Photocatalytic Hydrogen Evolution with Zeolite-Confined Perovskite Catalysts","authors":"Shiqin Gao, Wenyue Xia, Qingyi Li, Wenli Bao, Tianjun Zhang, Zhuangzhuang Ren, Kuo Bao, Donghai Mei, Bolun Wang, Jihong Yu","doi":"10.31635/ccschem.026.202607929","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607929","url":null,"abstract":"The rational design of high-performance photocatalysts often relies on sophisticated composite strategies to integrate multiple functional components, yet modulating the intrinsic electronic structure to optimize charge-carrier dynamics remains a significant challenge. Herein, we report that external pressure can serve as a powerful tool to precisely tailor the lattice strain of the semiconductor photocatalysts confined in the zeolite scaffold, thereby boosting the photocatalytic performance of the composite catalysts. Utilizing the zeolite-confined CsPbBr₃ perovskite (CsPbBr₃@S-1) as a design system, we demonstrate that the composite catalyst exhibits substantially enhanced photocatalytic performance after decompression. Comprehensive characterizations reveal that the enhancement is attributed to the pressure-induced structural amorphization and optimized band-gap structure of perovskite nanocrystals within the rigid zeolite scaffold, enabling efficient charge separation and transfer dynamics. Remarkably, the zeolite confinement endows the perovskite nanocrystals with exceptional resistance to ultra-high pressure, preserving the structural integrity and luminescent intensity far beyond the threshold pressure of bulk CsPbBr₃. This work not only introduces pressure as a versatile strategy for efficient photocatalyst design but also unveils a robust zeolite-protection mechanism, opening avenues for exploring and applying semiconductor materials under extreme environmental conditions.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"22 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fundamental Questions and Grand Challenges in Advancing Supramolecular Polymer Science","authors":"Zixiang Zhou, Zehuan Huang, Haotian Bai, Quan Chen, Xiaodong Chen, Amar Flood, Alexandra L. Ramos Figueroa, Zhao Gao, Atsushi Goto, Han Han, Feihe Huang, Zhekai Jin, Devika Karolly, Weiheng Lai, Hong Tho Le, Guangfeng Li, Hongbin Li, Yixuan Li, Kai Liu, Ming Liu, Yu Ou, Yunyan Qiu, Md. Mahamudul Hasan Rumon, Oren A. Scherman, Junqi Sun, Wei Tian, Chao Wang, Ruibing Wang, Shu Wang, Yuanyuan Wei, Frank Würthner, Jiang-Fei Xu, Xuehai Yan, Junqi Yi, Hang Yin, Chengqian Yuan, Xi Zhang","doi":"10.31635/ccschem.026.202607756","DOIUrl":"https://doi.org/10.31635/ccschem.026.202607756","url":null,"abstract":"The convergence of supramolecular chemistry and polymer science has stimulated intense interest in the design and development of diverse supramolecular polymeric systems. The dynamic, reversible, and highly tunable nature of noncovalent interactions imparts these materials with unique structure, emergent properties, and adaptive functions, positioning them as a transformative materials paradigm for a more sustainable future. In this review, we highlight recent advances in the field while articulating the fundamental questions and grand challenges that continue to shape its development, spanning polymerization methodologies, mechanistic understanding, materials construction, and impactful applications. By integrating recent advances with unresolved fundamental questions and grand challenges, this review aims to illuminate emerging opportunities and inspire the next generation of innovation in supramolecular polymer science.","PeriodicalId":9810,"journal":{"name":"CCS Chemistry","volume":"77 1","pages":""},"PeriodicalIF":11.2,"publicationDate":"2026-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148440839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}