Chemical Engineering Journal Advances最新文献

{"title":"Fabrication of quaternary Ag/BiOBr@Bi2MoO6/ZnO/g-C3N4 composite for direct Red 23 dye removal from water","authors":"Mojtaba Ghorbani,&nbsp;Majid Abdouss","doi":"10.1016/j.ceja.2026.101085","DOIUrl":"10.1016/j.ceja.2026.101085","url":null,"abstract":"<div><div>This study presents the design, synthesis, and performance evaluation of a quaternary Ag/BiOBr@Bi₂MoO₆/ZnO/g-C₃N₄ nanocomposite developed via a hydrothermal-photoassisted route for the near-visible-light-driven removal of Direct Red 23 (DR23) dye from aqueous solutions. Integrating plasmonic Ag nanoparticles with ZnO/g-C₃N₄ and BiOBr@Bi₂MoO₆ heterostructures produced a multi-junction system which is expected to enhanced photon absorption, charge carrier separation, and surface redox reactivity. Comprehensive characterization using FTIR, XRD, SEM, EDS, TEM, XPS, BET, UV-Vis DRS and PL analyses confirmed the formation of a coherent, a well-integrated heterostructured architecture with a narrowed optical band gap (2.64 eV) and significantly reduced recombination rates. The composite achieved 80.8 % degradation of DR23 within 110 min under UV-visible (near-visible) irradiation, showing improved performance compared with the corresponding binary systems.</div><div>Molecular dynamics (MD) simulations performed with Materials Studio and LAMMPS demonstrated strong dye-surface interactions and high thermodynamic stability (adsorption energy = -57.302 kcal.mol⁻¹.atom⁻¹), corroborating experimental efficiency. The simulations also revealed an optimal adsorption temperature of 340 K and an 88.15 % atomic removal rate of DR23 molecules. The proposed S-scheme charge transfer mechanism, facilitated by the plasmonic effect of Ag nanoparticles and favorable band alignment among the four semiconductors, enables efficient generation of reactive oxygen species (<strong>^.</strong>OH, <strong>^.</strong>O₂⁻ and ¹O₂). These reactive oxygen species initiate DR23 degradation primarily via cleavage of the azo (-N=N-) bond, followed by sequential deamination, desulfonation, aromatic ring opening and further oxidation into low-molecular-weight intermediates, as confirmed by LC-ESI-MS/MS analysis.</div><div>Overall, the enhanced photocatalytic performance of the Ag/BiOBr@Bi₂MoO₆/ZnO/g-C₃N₄ composite originates from the synergistic effects of heterojunction-induced charge separation, plasmonic enhancement by Ag nanoparticles and efficient generation of reactive oxygen species.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101085"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilization of silver-modified ostrich eggshell membrane in pervaporation for liquid fuel desulfurization","authors":"Atefeh Yari,&nbsp;Amir Abdolmaleki","doi":"10.1016/j.ceja.2026.101074","DOIUrl":"10.1016/j.ceja.2026.101074","url":null,"abstract":"<div><div>Sulfur compounds in crude oil cause significant corrosion and environmental pollution, driving the need for effective desulfurization. This study introduces, for the first time, a novel bio-membrane derived from the natural, protein-rich inner membrane of an ostrich eggshell (OESM) for pervaporative desulfurization. The pristine OESM demonstrated an inherent benzothiophene (BT) removal efficiency of 84.7% from a 500 ppm model fuel. To enhance performance, the membrane was modified with silver nanoparticles (AgNPs) via in-situ reduction by the membrane's hydroxyl groups. Comprehensive characterization by Raman spectroscopy, SEM-EDX, and XRD confirmed successful AgNP deposition with uniform distribution. The AgNP-modified membrane (Ag@OESM) achieved a remarkable 100% BT removal with an infinite enrichment factor and a permeation flux of 33.67 kg m⁻² h⁻¹ at room temperature. This exceptional performance is attributed to enhanced π-complexation between the AgNPs and the aromatic sulfur compound, facilitated by the membrane's preserved fibrous structure. In contrast, modifications with polydopamine reduced efficiency due to pore blockage. The Ag@OESM membrane combines high efficiency, operational simplicity, and a sustainable origin from waste material, presenting a pioneering advance in green separation technology.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101074"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-situ vacuum oxidation of ALD-SnO2 layer enabling highly efficient and stable perovskite solar cells","authors":"Sang Ho Won ,&nbsp;Yeon Woo Seok ,&nbsp;Yuna Choi ,&nbsp;Md.Mahbubur Rahman ,&nbsp;Tae Woong Kim","doi":"10.1016/j.ceja.2026.101072","DOIUrl":"10.1016/j.ceja.2026.101072","url":null,"abstract":"<div><div>Recent advances in perovskite solar cells (PSCs) have highlighted the urgent need for scalable commercialization technologies. Atomic layer deposition (ALD)-based SnO₂ has emerged as a promising electron transport layer (ETL), offering excellent reproducibility and uniformity. However, intrinsic defects such as oxygen vacancies limit further photovoltaic improvement. To address the defect problems, we developed an <em>In-Situ</em> vacuum oxidation (IVO) process that fundamentally enhances the intrinsic material quality of SnO₂ by incorporating controlled oxidation during ALD growth under vacuum conditions. This approach prevents oxygen vacancy formation in situ, improving the structural integrity of the oxide layer without external contamination risks associated with atmospheric exposure. The IVO-treated ALD-SnO₂ ETL achieved a power conversion efficiency of 23.39%, the highest reported value for single-layer ALD-SnO₂ PSCs while retaining 87% of initial performance after 1500 h without encapsulation, demonstrating exceptional long-term stability. This strategy presents a viable pathway toward commercialization of high-performance PSCs.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101072"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A microfluidic spray drying approach for developing lipid nanoparticles dry powder via anti-solvent precipitation","authors":"Yipiao Zhang ,&nbsp;Yang Liu ,&nbsp;Zhu Yang ,&nbsp;Chuanpin Chen ,&nbsp;Xingchen Zhou ,&nbsp;Suhong Chen ,&nbsp;Hongliang Zheng","doi":"10.1016/j.ceja.2026.101073","DOIUrl":"10.1016/j.ceja.2026.101073","url":null,"abstract":"<div><div>The development of novel drug dosage forms with high drug activity and enhanced bioavailability continues to pose a significant challenge in the pharmaceutical industry. Currently, lipid nanoparticles (LNPs) have been widely recognized as safe and efficient nanomedicine delivery systems; however, they exhibit thermodynamic instability. To address these challenges, this study developed a novel microfluidic spray drying (MFSD) platform by integrating the anti-solvent precipitation (ASP) method with gas spray drying, enabling continuous preparation of Rg3-loaded spray-dried lipid nanoparticles (Rg3-SD LNPs) dry powder. Key parameters, including solvent/antisolvent concentration, flow rate ratio, and gas pressure, were optimized to produce monodisperse and stable nanoparticles. The influence of excipient type, concentration, and heating temperature on dry powder was also investigated. Characterization confirmed long-term stability of the dry powder and low organic solvent residue, while <em>in vivo</em> pharmacokinetic study in rats demonstrated significantly enhanced bioavailability. The obtained LNPs dry powder demonstrated enhanced long-term storage stability and oral bioavailability, effectively overcoming the problems of thermodynamic instability of LNPs and low bioavailability of poorly soluble drugs. This study underscores the potential of the MFSD platform as a scalable and efficient approach to enhance the solubility, long-term storage stability, and bioavailability of poorly water-soluble drugs and provides a practical and feasible method for preparing LNPs dry powder.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101073"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced oxidative leaching of copper-iron sulfides using photo-assisted electrochemical advanced oxidation processes","authors":"Juan Pablo Fuentes ,&nbsp;Sapana Jadoun ,&nbsp;Orlando Yepsen ,&nbsp;Ricardo Salazar-González ,&nbsp;Camilo Rivera-Vera ,&nbsp;Lorena Cornejo-Ponce ,&nbsp;David Conteras ,&nbsp;Héctor D. Mansilla ,&nbsp;Jorge Yáñez","doi":"10.1016/j.ceja.2026.101060","DOIUrl":"10.1016/j.ceja.2026.101060","url":null,"abstract":"<div><div>In this work, the effectiveness of electro-Fenton and photoelectro-Fenton processes for enhancing the oxidative leaching of copper-iron sulfide minerals such as chalcopyrite (CuFeS₂) and bornite (Cu₅FeS₄) in aqueous suspension was investigated. Electro-Fenton experiments were conducted in an electrochemical reactor equipped with a boron-doped diamond anode and a carbon-polytetrafluoroethylene gas-diffusion electrode as a cathode. The results show that, after 3 h, CuFeS₂ and Cu₅FeS₄ reached Cu and Fe leaching rates of 20% and 26%, respectively. These findings demonstrate enhanced performance under mild conditions compared to conventional leaching processes. Additionally, UV–Vis light irradiation was evaluated to assess the contribution of light-induced mechanisms, including photocorrosion and photo-Fenton reactions, establishing that the enhancement in leaching yield was relatively less significant (≈5%). The involvement of radical species such as hydroxyl and sulfate radicals was evaluated using in-situ electron paramagnetic resonance spectroscopy. Furthermore, the role of physisorbed hydroxyl radicals was evaluated by using an active metal mixed oxide anode in place of boron-doped diamond anode. This study demonstrates that in-situ electro-generated H₂O₂, together with dissolved iron (Fe²⁺ and Fe³⁺) and copper ions (Cu²⁺), can trigger Fenton, and photo-Fenton mechanisms, thereby promoting the oxidative dissolution of sulfide minerals. These findings provide a proof of concept for a more sustainable and alternative approach to mineral resource leaching<strong>.</strong></div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101060"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146098719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated molecular riser-regenerator modeling via Radau collocation for FCC operational optimization","authors":"Wuwenjie Song ,&nbsp;He Yao ,&nbsp;Yan Gong ,&nbsp;Nan Zhang","doi":"10.1016/j.ceja.2026.101078","DOIUrl":"10.1016/j.ceja.2026.101078","url":null,"abstract":"<div><div>Fluid catalytic cracking (FCC) operation depends on tight heat coupling between an endothermic riser and an exothermic regenerator. Decoupled models often mispredict feasible temperatures and product trade-offs. This study develops an integrated framework that couples a 23-lump riser kinetics, derived from Molecular-Type Homologous Series (MTHS), with a four-reaction regenerator to compute flue-gas composition and heat release. Unit-level heat and mass balances are imposed endogenously so that catalyst circulation and feasible operating envelopes arise from the model solution. The steady DAE system is transcribed to a sparse nonlinear program using Radau IIA collocation and solved in CasADi/Ipopt. Kinetic parameters and reaction enthalpies are regressed to industrial data under physical bounds. The validated model reproduces major product yields, temperature profiles, and flue-gas compositions with small errors. Against plant data, absolute deviations are within 0.4 wt% and the key product yields are within ±1% relative error, while minor products (e.g., slurry/dry gas) show larger deviations. The operational optimization in the case studies shows up to 7.76% profit increase by coordinated adjustment of air rate, feed preheat, and heat extraction, demonstrating that the framework offers a mechanistically interpretable, computationally robust tool for decision support in industrial FCC units.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101078"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Stepwise membrane modification for nutrient recovery: Linking exclusion mechanisms to performance","authors":"Marrit van der Wal ,&nbsp;Aylin Kinik ,&nbsp;Marc van Maris ,&nbsp;Zandrie Borneman ,&nbsp;Kitty Nijmeijer","doi":"10.1016/j.ceja.2026.101077","DOIUrl":"10.1016/j.ceja.2026.101077","url":null,"abstract":"<div><div>Niche applications like nutrient recovery require membranes with specific ion retention for separation like for example NH₄⁺ and K⁺. Membrane modification is a promising strategy for developing application-specific separation properties. In this study, a three-step modification approach was applied to an ultrafiltration polyacrylonitrile membrane support for ion-specific retention. First, alkaline hydrolysis of the membrane support introduced negatively charged carboxylate groups enabling Donnan exclusion with a significant decrease in water flux due to pore swelling based on permeance and salt retention measurements. Second, the deposition of polyelectrolyte multilayers adds additional size exclusion to the Donnan exclusion by partially covering membrane pores, thereby increasing the retention of monovalent and multivalent ions. Third, the retention of salts is further enhanced by crosslinking forming a rigid polymer network improving exclusion. Moreover, the crosslinking provides a difference in the retention of NH₄⁺ and K⁺due to the difference in their dehydration energy resulting in nutrient separation. The selectivity can be further improved by increasing the pH of the manure digestate to permeate neutral NH₃ while retaining K⁺ providing separation based on charge difference. Overall, the stepwise membrane modification shows a versatile pathway to tailor ion-specific retention, offering a strong potential for nutrient recovery and other niche applications.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101077"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Zeolite architecture and composition govern selective adsorption of organophosphorus compounds","authors":"Faezeh Gorgichi ,&nbsp;Mehdi Shahraki ,&nbsp;Tayebeh Hadadi ,&nbsp;Mar Ríos-Gutiérrez","doi":"10.1016/j.ceja.2026.101068","DOIUrl":"10.1016/j.ceja.2026.101068","url":null,"abstract":"<div><div>The adsorption of organophosphorus compounds (OPCs) in zeolites was systematically investigated through a multi-framework computational study that integrates molecular descriptors with host structural parameters. Four representative guests-trimethylphosphine oxide (TMPO), dimethylmethoxy phosphine (DMMPO), dimethyl methylphosphonate (DMMP), and trimethyl phosphonate (TMP)-were examined across seven zeolite frameworks (MFI, MEL, BEA, AFI, and FAU with variable Si/Al ratios). Gas- - and liquid-phase simulations revealed pronounced phase-dependent variations in molecular volume and polarity, with TMP exhibiting the largest solvent-accessible surface area. Adsorption energetics-including adsorption energy (Eads), deformation energy (E_def), differential adsorption energy (dE_ads/dNi), and isosteric heat (Qst)-were employed to evaluate binding strength, site heterogeneity, and water competition. Framework-specific analyses demonstrated that medium-pore zeolites (MFI, MEL) favor compact polar sorbates but penalize bulky guests, BEA accommodates both compact and bulky molecules with high loadings, AFI’s one-dimensional channels selectively stabilize elongated species, and FAU’s supercages eliminate steric penalties while the Si/Al ratio tunes polarity and hydrophilicity. Integrated performance mapping identified DMMP as the most consistent sorbate across frameworks, DMMPO as the most balanced in aqueous systems, TMP as highly framework-dependent, and TMPO as strongly adsorbed but water-sensitive. Modeled adsorption capacities (≈25–110 mg·g⁻¹) aligned with experimental ranges (30–200 mg·g⁻¹), validating the predictive framework. Molecular dynamics simulations combined with mean square displacement (MSD) and radial distribution function (RDF) analyses elucidate how zeolite topology controls the diffusion of organophosphorus compounds. Across MFI, MEL, BEA, FAU, and AFI frameworks, simulated diffusivities consistently fall within the experimental window of 10⁻⁶-10⁻⁵ cm²/s and reproduce framework‑dependent inversions in mobility order. RDF profiles reveal that polarity‑driven short‑range anchoring and mid‑range clustering dictate whether confinement suppresses or enhances transport, explaining why TMP is fast in MFI but the slowest in MEL, while DMMP shifts from the slowest in MFI to the quickest in BEA and FAU. The close agreement between simulated and experimental diffusion coefficients for DMMP, TMP, and related compounds validates the predictive power of this computational approach. These findings provide a unified mechanistic understanding of organophosphorus mobility in zeolites and offer guidance for the rational design of porous materials for selective adsorption and separation.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101068"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Electrochemical sensing of Fe3+-EDDS in realistic water matrices: Validation and techno-economic assessment for photo-Fenton processes","authors":"Constanza J. Venegas ,&nbsp;Franco Tamayo ,&nbsp;Alejandro Cabrera-Reina ,&nbsp;Paulina Sierra-Rosales ,&nbsp;Sara Miralles-Cuevas","doi":"10.1016/j.ceja.2026.101067","DOIUrl":"10.1016/j.ceja.2026.101067","url":null,"abstract":"<div><div>This study presents the first electrochemical sensor specifically designed to detect the Fe³⁺-EDDS complex, a widely used chelating agent in homogeneous photocatalysis for wastewater treatment at near-neutral pH. Measurements were performed off-line using a glassy carbon electrode (GCE) modified with multi-walled carbon nanotubes (MWCNTs), thereby enhancing sensitivity and electron-transfer capability. Experimental parameters, including MWCNT concentration (0.5–2.0 mg/mL), accumulation time (0–4 min), and Fe³⁺-EDDS concentration (0.01–0.10 mM), were optimized to maximize performance. The sensor exhibited a strong linear response (R² = 0.992) with a sensitivity of 29.4 µA/mM and a detection limit of 0.006 mM. In real wastewater effluents, signal attenuation led to a narrower effective linear range, with reduced proportionality above ∼0.06 mM Fe³⁺-EDDS, highlighting both matrix effects and the need for matrix-specific calibration. Its long-term stability was confirmed for over 100 days using stored MWCNT dispersions. A robust correlation with UHPLC/DAD measurements (Pearson <em>r</em> &gt; 0.91, R² &gt; 0.95) validated the sensor's accuracy. The sensor was also tested in a pilot-scale UVA-LED photoreactor to monitor Fe³⁺-EDDS degradation under different Fe³⁺ and EDDS dosages. Results demonstrated the sensor's suitability for real-time monitoring of catalyst availability during advanced oxidation processes (AOPs). Additionally, a techno-economic analysis indicated a 78.3% reduction in per-sample cost relative to UHPLC/DAD, underscoring its potential for routine, cost-effective monitoring in wastewater treatment. This novel platform enables cost-effective, off-line monitoring of iron chelate availability in AOPs and provides a basis for future development toward real-time sensing in complex water matrices.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101067"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Process intensification of direct biomass straw conversion to Furfural via circular NaDES platform","authors":"Salvatore Romano ,&nbsp;Chiara Bruschetta ,&nbsp;Silvia Tabasso ,&nbsp;Emanuela Calcio Gaudino ,&nbsp;Monica Nardi ,&nbsp;Antonio Procopio","doi":"10.1016/j.ceja.2026.101066","DOIUrl":"10.1016/j.ceja.2026.101066","url":null,"abstract":"<div><div>The valorization of lignocellulosic biomass represents a key strategy for the sustainable production of platform chemicals without food resources.. Amonf these, furfural is a pivotal C5 building block with applicationsin biofuels, fine chemicals, and pharmaceuticals. In this study, we report a direct and efficient conversion of raw wheat straw to furfural using a natural deep eutectic solvent (NaDES) under mild microwave-assisted conditions, without any preliminary biomass pretreatment.wheat straw to furfural using a natural deep eutectic solvent (NaDES) under mild microwave-assisted conditions, without any preliminary biomass pretreatment.</div><div>A choline chloride/oxalic acid (1:1) NaDES enabled the selective transformation of the hemicellulosic fraction, affording furfural with &gt;99% selectivity and no detectable HMF formation, as confirmed by GC–MS analysis. The process operates at low temperature (80 °C) and short reaction times, and allows straightforward product separation through cooling and centrifugation. Scale-up experiments demonstrated the robustness and reproducibility of the protocol, with furfural yields up to 20 wt% from untreated straw and 27 wt% from delignified biomass.</div><div>Importantly, residual furfural remaining in the aqueous phase was further valorized in situ into bi-functionalized cyclopentenones, enabling complete utilization of the produced platform molecule and reinforcing the circular nature of the process. Overall, this work presents a NaDES-based platform for the selective C5 valorization of lignocellulosic biomass, combining process intensification, high selectivity, and circular economy principles.</div></div>","PeriodicalId":9749,"journal":{"name":"Chemical Engineering Journal Advances","volume":"26 ","pages":"Article 101066"},"PeriodicalIF":7.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146172146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}