Case Reports in Endocrinology最新文献_第6页

Riedel's Thyroiditis: Pitfalls in Diagnosis and Subsequent Complications. 里德尔甲状腺炎:诊断缺陷及后续并发症。

IF 1.1

Case Reports in Endocrinology Pub Date : 2023-01-01 DOI: 10.1155/2023/9989953

R Pandev, M Khan, V Ratheesh

{"title":"Riedel's Thyroiditis: Pitfalls in Diagnosis and Subsequent Complications.","authors":"R Pandev, M Khan, V Ratheesh","doi":"10.1155/2023/9989953","DOIUrl":"https://doi.org/10.1155/2023/9989953","url":null,"abstract":"<p><p>Riedel's thyroiditis is a rare disease of chronic inflammation with fibrotic infiltration of the thyroid gland and its surrounding vital structures. Due to its low incidence, there are often delays in diagnosis as it is commonly mistaken for other thyroid diseases. We report the case of a 34-year-old female patient who presented with a firm, enlarged mass in the neck, compression symptoms, and hypothyroidism. Lab tests showed elevated A-TG (thyroglobulin antibodies) and A-TPO (thyroid peroxidase antibodies) levels. Based on the disease presentation and supporting lab findings, the patient was misdiagnosed with Hashimoto's thyroiditis and treated accordingly. Yet the patient's symptoms grew progressively worse. She was discovered to have severe tracheal compression and bilateral RLN (recurrent laryngeal nerve) palsy. Tracheotomy became a necessary surgical intervention after the development of respiratory failure, but this procedure was complicated by the development of an intraoperative pneumothorax. After an open biopsy, histology revealed Riedel's thyroiditis. A new treatment was introduced, with which the patient's condition improved. However, she continued to suffer from the open tracheocutaneous fistula left by the tracheostomy, which adversely affected her everyday life. A follow-up operation was performed to close the fistula. In this case report, we discuss the consequences of misdiagnosing the patient and delaying the appropriate treatment for her disease.</p>","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"2023 ","pages":"9989953"},"PeriodicalIF":1.1,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9391105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Sitosterolemia: A Case Report and a Concise Literature Review. 谷固醇血症:1例报告及简明文献回顾。

IF 1.1

Case Reports in Endocrinology Pub Date : 2023-01-01 DOI: 10.1155/2023/4451595

Moeber M Mahzari

引用次数: 1

A Rare Observation of Brachymetacarpia and Brachymetatarsia in a Patient with Primary Idiopathic Hypoparathyroidism. 原发性特发性甲状旁腺功能减退症患者掌跖不足和跖不足的罕见观察。

IF 1.1

Case Reports in Endocrinology Pub Date : 2023-01-01 DOI: 10.1155/2023/4149677

Parackrama Karunathilake, Arun Rajaratnam, W K S Kularatne

引用次数: 0

Sodium-Glucose Transport Protein 2 Inhibitors Association with Euglycemic Diabetic Ketoacidosis. 钠-葡萄糖转运蛋白2抑制剂与糖尿病酮症酸中毒的关系。

IF 1.1

Case Reports in Endocrinology Pub Date : 2023-01-01 DOI: 10.1155/2023/6835882

Caroline Wojtas, Alex P Rasarmos, Naja Naddaf

引用次数: 1

Management of Neonatal Diabetes due to a KCNJ11 Mutation with Automated Insulin Delivery System and Remote Patient Monitoring. KCNJ11突变引起的新生儿糖尿病的自动胰岛素输送系统和远程患者监测的管理。

IF 1.1

Case Reports in Endocrinology Pub Date : 2023-01-01 DOI: 10.1155/2023/8825724

Ming Yeh Lee, Anna L Gloyn, David M Maahs, Priya Prahalad

引用次数: 0

A Case of Subacute Thyroiditis following COVID-19 Infection COVID-19感染后亚急性甲状腺炎1例

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-31 DOI: 10.1155/2022/2211061

Sameh Samir Elawady, Diwakar Phuyal, R. Shah, L. Mirza

{"title":"A Case of Subacute Thyroiditis following COVID-19 Infection","authors":"Sameh Samir Elawady, Diwakar Phuyal, R. Shah, L. Mirza","doi":"10.1155/2022/2211061","DOIUrl":"https://doi.org/10.1155/2022/2211061","url":null,"abstract":"Background/Objective. Since the start of the pandemic, COVID-19 has been associated with several postinfection complications. Subacute thyroiditis (SAT) is an inflammatory disorder of the thyroid that has been reported in the literature following COVID-19 infection. We report a case of SAT following COVID-19 infection. Case Report. A 33-year-old female presented with neck pain two weeks after resolution of COVID-19 infection. Her thyroid function tests together with ultrasonographic pictures were consistent with SAT. She was treated with three rounds of medrol dose pack without relief. She then required oral prednisone 40 mg per day and ibuprofen 800 mg once daily for another several weeks that eventually resulted in improvement of her symptoms. Discussion. SAT most commonly occurs in females during or after viral infection. The usual course of the disease is hyperthyroidism then hypothyroidism followed by resolution. SAT is clinically diagnosed by lab findings of decreased TSH in the setting of negative thyroid-stimulating and thyroid peroxidase antibodies. All these data are consistent with our case. Conclusion. SAT following COVID-19 infection presents with a similar clinical presentation and course as the classic form of SAT, but we should consider the fact that a high-dose corticosteroid treatment might be necessary for such patients.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"4 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89492327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Primary Hypothyroidism with Pituitary Hyperplasia in an Omani Girl 阿曼女孩原发性甲状腺功能减退伴垂体增生1例

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-29 DOI: 10.1155/2022/3382612

Wafa Abdallah Fadle, Ali Al Reesi, Saud Al-Shabibi, Maryam Khamis Al-Badi

引用次数: 0

Central Diabetes Insipidus Induced by Acute Myeloid Leukemia with DNMT3A Mutation 急性髓系白血病伴DNMT3A突变致中枢性尿崩症

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-23 DOI: 10.1155/2022/2750146

P. Lakshmanan, Heena Asnani, David Knorr

{"title":"Central Diabetes Insipidus Induced by Acute Myeloid Leukemia with DNMT3A Mutation","authors":"P. Lakshmanan, Heena Asnani, David Knorr","doi":"10.1155/2022/2750146","DOIUrl":"https://doi.org/10.1155/2022/2750146","url":null,"abstract":"Central diabetes insipidus (CDI) is an uncommon complication of acute myeloid leukemia (AML). Patients present with polyuria either preceding or at the time of diagnosis of AML. We describe the case of a 36-year-old male who presented with a subacute onset of polyuria, polydipsia, nocturia, and fatigue. After an extensive workup, he was diagnosed with AML/CMML (chronic myelomonocytic leukemia) with a normal karyotype with DNMT3A, CBFB, and PTPN11 mutations. Further workup of the polyuria with a water deprivation test helped confirm the diagnosis of CDI along with MRI findings suggestive of hypophysitis. In this report, we analyze the clinical workup for AML and CDI and report the possibility of extramedullary leukemic infiltration associated with DNMT3A mutation, which has been reported as one of the mechanisms in the existing literature. We also discuss other theories hypothesized to cause CDI in AML patients with abnormal karyotypes. Our patient progressed to AML from CMML-2 after a cycle of decitabine, with confirmed gingival and presumed central nervous system (CNS) involvement. He is in minimal residual disease (MRD)-negative complete remission after induction with a CNS-active acute lymphoblastic leukemia-2 regimen. He also received double umbilical cord blood transplantation, conditioned with cyclophosphamide, fludarabine, thiotepa, and total body irradiation (TBI) of 4 Gy. This was complicated by engraftment syndrome for which he is currently being managed. CDI of the patient was corrected by desmopressin administration.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"13 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78498028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Gonadoblastoma with Dysgerminoma Presenting as Virilizing Disorder in a Young Child with 46, XX Karyotype: A Case Report and Review of the Literature 性腺母细胞瘤合并异常生殖细胞瘤在46,XX核型的幼儿中表现为男性化障碍:1例报告和文献复习

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-05-23 DOI: 10.1155/2022/5666957

Prathamesh Chandrapattan, A. Jena, R. Patnayak, S. Mangaraj, Sujata Naik, Saroj Panda

{"title":"Gonadoblastoma with Dysgerminoma Presenting as Virilizing Disorder in a Young Child with 46, XX Karyotype: A Case Report and Review of the Literature","authors":"Prathamesh Chandrapattan, A. Jena, R. Patnayak, S. Mangaraj, Sujata Naik, Saroj Panda","doi":"10.1155/2022/5666957","DOIUrl":"https://doi.org/10.1155/2022/5666957","url":null,"abstract":"Gonadoblastoma is a neoplasm containing an intimate mixture of germ cells and elements resembling immature granulosa or Sertoli cells. It has been considered as in situ germ cell malignancy that can be associated with malignant components. The tumor has been reported to almost exclusively develop in various types of gonadal gene mutation syndromes, such as in pure or mixed gonadal dysgenesis and among females carrying Y chromosome material. However, it can be rarely present in normal women with 46, XX karyotype. Ovarian gonadoblastoma presenting with signs of contrasexual puberty in a young female child with normal 46, XX karyotype is an extremely rare clinical entity and seldom reported in the literature. We report a case of a nine-year-old girl child who presented with signs of virilization and contrasexual pubertal development. A detailed clinical evaluation along with supportive biochemical and radiological findings pointed to the presence of a virilizing ovarian tumor. The patient underwent right salpingo-oophorectomy, pelvic node dissection, and infracolic omentectomy. The excised tumor was confirmed to be gonadoblastoma which was overgrown by dysgerminoma on histopathological evaluation. The presence of associated malignant tumors (like dysgerminoma) should always be ruled out in cases of gonadoblastoma.","PeriodicalId":9621,"journal":{"name":"Case Reports in Endocrinology","volume":"97 1","pages":""},"PeriodicalIF":1.1,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75823128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Myxedema Coma Associated with Macroprolactinoma: Case Report and Review of the Literature 黏液性水肿昏迷伴巨泌乳素瘤:病例报告及文献复习

IF 1.1

Case Reports in Endocrinology Pub Date : 2022-04-28 DOI: 10.1155/2022/1591616

Elizabeth Omoniyi, R. Robbins

引用次数: 0