Case Reports in Nephrology最新文献_第4页

A Case of Acute Colonic Pseudo-Obstruction (Ogilvie's Syndrome) in a Nonsurgical Patient with Plasma Cell Leukemia. 血浆细胞白血病非手术患者急性结肠假性梗阻(奥吉维综合征)1例。

Case Reports in Nephrology Pub Date : 2022-11-23 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6431248

Akbar Hamid, Jacob Sabu, Omar Elhawary, Isha Puri, Moro Salifu, Man Oh, Mary Mallappallil

引用次数: 1

Disseminated Mycobacterium Tuberculosis and IgA Nephropathy. 弥散性结核分枝杆菌与IgA肾病。

Case Reports in Nephrology Pub Date : 2022-11-01 eCollection Date: 2022-01-01 DOI: 10.1155/2022/3785713

Gordon Audley, Bianca Davidson, Erika Jones, Brendon Price, Brian Rayner, Nicola Wearne, Zibya Barday

引用次数: 0

An Exceptional Case of Light Chain Only Variant of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits Secondary to Chronic Lymphocytic Leukemia: A Case Report and Review of the Literature. 慢性淋巴细胞白血病继发单克隆免疫球蛋白沉积的增殖性肾小球肾炎轻链变异一例:1例报告及文献复习。

Case Reports in Nephrology Pub Date : 2022-10-19 eCollection Date: 2022-01-01 DOI: 10.1155/2022/9207282

José C De La Flor, Jacqueline Apaza, Francisco Díaz, Edna Sandoval, Tania Linares, Alexander Marschall, Patricia Núñez, Andrea Cecilia Rivas-Nieto, Elisa Ruiz

{"title":"An Exceptional Case of Light Chain Only Variant of Proliferative Glomerulonephritis with Monoclonal Immunoglobulin Deposits Secondary to Chronic Lymphocytic Leukemia: A Case Report and Review of the Literature.","authors":"José C De La Flor, Jacqueline Apaza, Francisco Díaz, Edna Sandoval, Tania Linares, Alexander Marschall, Patricia Núñez, Andrea Cecilia Rivas-Nieto, Elisa Ruiz","doi":"10.1155/2022/9207282","DOIUrl":"https://doi.org/10.1155/2022/9207282","url":null,"abstract":"We present the case of an 86-year-old Caucasian male with an 11-year history of low-grade chronic lymphocytic leukemia (CLL) presenting with nephrotic syndrome (NS). Renal biopsy findings showed a diffuse mesangial and endocapillary proliferative glomerulonephritis (GN) lesion with fine granular deposits, consistent with a rare morphologic variant of proliferative glomerulonephritis with monoclonal immunoglobulin deposits (PGNMID)-lambda light chain (LC) only. Monthly combination therapy of rituximab (500 mg/m2 on day 1), fludarabine (30 mg/m2 on days 1-3), and cyclophosphamide (750 mg/m2 on days 1-3) was administered. Five courses of this regimen resulted in hematological remission, as well as a partial renal response with a reduction in the spot urine protein-to-creatinine ratio (UPCR) of 815.3 mg/g (reduction > 50% proteinuria without improvement in kidney function). This condition is a rare morphological variant of PGNMID, poorly described in CLL patients. We review the literature and suggest that this case provides sheds light on the unknown pathophysiological mechanisms of monoclonal immunoglobulins (MIg)-mediated glomerular damage in CLL patients, and may be helpful for the investigation of a more effective treatment.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":" ","pages":"9207282"},"PeriodicalIF":0.0,"publicationDate":"2022-10-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40656382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cell-Free and Concentrated Ascites Reinfusion Therapy during Hemodialysis for Intradialytic Hypotension and Intractable Ascites 无细胞和浓缩腹水回输治疗透析期间的低血压和顽固性腹水

Case Reports in Nephrology Pub Date : 2022-10-15 DOI: 10.1155/2022/7099227

Hideyuki Hayasaka, K. Ito, S. Ookawara, Masaya Kofuji, Takayuki Uchida, S. Kawamura, Ayumi Gomyo, Haruhisa Miyazawa, Yuichiro Ueda, Keiji Hirai, S. Kimura, N. Momose, S. Kako, Yoshiyuki Morishita

引用次数: 0

Langerhans Cell Histiocytosis Manifests with Acute Severe Hypernatremia during Hospitalization. 朗格汉斯细胞组织细胞增多症在住院期间表现为急性严重高钠血症。

Case Reports in Nephrology Pub Date : 2022-10-14 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6120644

Kullaya Takkavatakarn, Hansamon Poparn, Pisut Katavetin

引用次数: 0

Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma. 恶性间皮瘤并发肾病综合征和冷球蛋白血症1例。

Case Reports in Nephrology Pub Date : 2022-09-28 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8677293

Kei Nagai, Hiroaki Tachi, Kohei Inoue, Atsushi Ueda

{"title":"Concomitant Nephrotic Syndrome and Cryoglobulinemia in a Case of Malignant Mesothelioma.","authors":"Kei Nagai, Hiroaki Tachi, Kohei Inoue, Atsushi Ueda","doi":"10.1155/2022/8677293","DOIUrl":"https://doi.org/10.1155/2022/8677293","url":null,"abstract":"Malignant pleural mesothelioma is rarely associated with nephrotic syndrome. Cryoglobulinemia is found in various pathological statuses, such as hepatitis C virus infection but rarely in malignant neoplasms. We recently encountered a patient with malignant mesothelioma coincident with nephrotic syndrome and cryoglobulinemia in the course of chemotherapy. A 60-year-old man employed as a building painter was diagnosed with malignant mesothelioma by lung biopsy two years earlier and was started on chemotherapy. Nivolumab seemed effective in controlling mesothelioma, but skin immune-related adverse events occurred during the course of treatment. After discontinuation of nivolumab and administration of gemcitabine as an alternative therapy, the patient was referred to a nephrologist because of the subsequent development of edema, renal injury, and proteinuria. Following the investigation, he was diagnosed with nephrotic syndrome and cryoglobulinemia with C4-dominant cold activation. However, a percutaneous renal biopsy could not be performed due to persistent severe cough induced by pleural involvement. The patient died a little over three years after the pathological diagnosis of pleural mesothelioma. Our case had three key features nephrotic syndrome was possibly associated with malignant mesothelioma; cryoglobulinemia occurred in malignant mesothelioma; and concomitant nephrotic syndrome and cryoglobulinemia occurred after chemotherapy. Unfortunately, our rare case lacks a basis in renal pathology or evidence of links between the pathogenesis of malignant mesothelioma, cryoglobulinemia, and nephrotic syndrome. This case does not provide a causal mechanism, but may be worth adding to the case list as one of the rare renal involvement in a patient with malignant mesothelioma.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":" ","pages":"8677293"},"PeriodicalIF":0.0,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9534674/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33497086","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

A Rare Case of Extensive Eggshell Intestinal Wall Peritoneal Calcification in a Long-Term Continuous Peritoneal Dialysis Patient. 一例长期连续腹膜透析患者广泛的蛋壳肠壁腹膜钙化。

Case Reports in Nephrology Pub Date : 2022-09-26 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2104120

Erasmia Sampani, Chrysostomos Dimitriadis, Efstratios Kasimatis, Evangelos Memmos, Aikaterini Papagianni

引用次数: 0

Renal Involvement of CD20-Negative Intravascular Large B Cell Lymphoma with Neurological Manifestations. 伴有神经系统表现的cd20阴性血管内大B细胞淋巴瘤累及肾脏。

Case Reports in Nephrology Pub Date : 2022-09-10 eCollection Date: 2022-01-01 DOI: 10.1155/2022/8613965

Faten Aqeel, Serena M Bagnasco, Duvuru Geetha

引用次数: 0

Spontaneous Retroperitoneal Bleeding as a Complication of Unusual Renal Paraganglioma. 自发性腹膜后出血是罕见肾副神经节瘤的并发症。

Case Reports in Nephrology Pub Date : 2022-08-30 eCollection Date: 2022-01-01 DOI: 10.1155/2022/6882451

Tawfeeq I Sangey, Hamim Abdul Rusheke, Ansaar I Sangey, Nimishkumar Chaya, Advera Ngaiza

引用次数: 0

A Case of Paediatric Anti-Glomerular Basement Membrane Disease Associated with Thrombotic Thrombocytopenic Purpura. 儿童抗肾小球基底膜病合并血栓性血小板减少性紫癜1例。

Case Reports in Nephrology Pub Date : 2022-08-27 eCollection Date: 2022-01-01 DOI: 10.1155/2022/2676696

Joseph McAllister, Pradeep Nagisetty, Kay Tyerman

{"title":"A Case of Paediatric Anti-Glomerular Basement Membrane Disease Associated with Thrombotic Thrombocytopenic Purpura.","authors":"Joseph McAllister, Pradeep Nagisetty, Kay Tyerman","doi":"10.1155/2022/2676696","DOIUrl":"https://doi.org/10.1155/2022/2676696","url":null,"abstract":"Anti-GBM disease is a rare vasculitis that causes rapid progressive glomerulonephritis and pulmonary haemorrhage. It is usually an adult diagnosis with isolated paediatric cases reported. Thrombotic thrombocytopenic purpura (TTP) is a rare thrombotic microangiopathy mainly affecting adults that causes multiorgan ischaemia, microangiopathic haemolytic anaemia, and thrombocytopenia. We present the first paediatric case of concurrent anti-GBM disease and TTP. A 14-year-old boy presented with acute kidney failure and severe pulmonary haemorrhage due to anti-GBM disease, confirmed on auto-antibody testing. There was thrombocytopenia and moderately low ADAMTS13 activity suggestive of TTP. The renal prognosis was poor with a need for dialysis. He was severely unwell with pulmonary haemorrhages requiring the use of extracorporeal membrane oxygenation (ECMO). His disease was treated with corticosteroids, plasma exchange (PEX), rituximab, and cyclophosphamide, resulting in remission. Anti-GBM disease is rare in children but should be considered in those presenting with acute kidney injury, particularly where there has been exposure to pulmonary irritants. An aggressive presentation warrants aggressive treatment with methylprednisolone, PEX, and cyclophosphamide. Rituximab may benefit patients that have concurrent TTP. TTP may exacerbate pulmonary disease, but complete respiratory recovery is possible. Disease relapse is rare in the paediatric age group, and these patients are candidates for kidney transplantation.","PeriodicalId":9604,"journal":{"name":"Case Reports in Nephrology","volume":" ","pages":"2676696"},"PeriodicalIF":0.0,"publicationDate":"2022-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9440844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40352291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2