Case Reports in Ophthalmological Medicine最新文献

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Three Cases of Arteritic Anterior Optic Neuropathy Several Months after COVID-19 Vaccination. 新冠肺炎疫苗接种数月后动脉性前视神经病变3例。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-09-11 eCollection Date: 2023-01-01 DOI: 10.1155/2023/8845850
Yuichi Yamamoto, Ken Ogino, Satoshi Yasuhara, Yu Kawashima, Toshiya Miki
{"title":"Three Cases of Arteritic Anterior Optic Neuropathy Several Months after COVID-19 Vaccination.","authors":"Yuichi Yamamoto,&nbsp;Ken Ogino,&nbsp;Satoshi Yasuhara,&nbsp;Yu Kawashima,&nbsp;Toshiya Miki","doi":"10.1155/2023/8845850","DOIUrl":"https://doi.org/10.1155/2023/8845850","url":null,"abstract":"<p><strong>Background: </strong>Vaccines have been approved worldwide to control the coronavirus disease-19 (COVID-19). However, the postvaccination side effects remain controversial. Here, we describe three Japanese cases of arteritic anterior ischaemic optic neuropathy (AAION) following COVID-19 vaccination. <i>Case presentation</i>. The first case involved an 87-year-old woman who presented with vision loss in the right eye 2 months after her second COVID-19 vaccine and in the left eye 2 days later. The second case involved an 88-year-old woman who presented with vision loss in both eyes 3 months after receiving a second vaccine. The third case involved an 80-year-old man who presented with vision loss in the right eye 5 months after receiving a second vaccine. The C-reactive protein level and erythrocyte sedimentation rate were elevated in all patients. Biopsy of the temporal artery or auricular cartilage showed arteritic occlusion in case 2 and polychondritis in case 3. These patients were referred to a local Japanese hospital in 2021 over a period of no longer than 3 months.</p><p><strong>Conclusion: </strong>We observed three cases of AAION after the affected individuals received their second COVID-19 vaccine. Further long-term investigations of ophthalmological events after COVID-19 vaccination are warranted.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"8845850"},"PeriodicalIF":0.9,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10506880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41112376","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation. 白内障摘出联合晶体注入术后眼内炎。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/3132866
Johnson Huang, Minh T Nguyen, Mai Tsukikawa, Andrew Chen
{"title":"Postoperative Endophthalmitis after Combined Cataract Extraction and iStent Inject Implantation.","authors":"Johnson Huang,&nbsp;Minh T Nguyen,&nbsp;Mai Tsukikawa,&nbsp;Andrew Chen","doi":"10.1155/2023/3132866","DOIUrl":"https://doi.org/10.1155/2023/3132866","url":null,"abstract":"<p><p><i>Purpose.</i> To report a case of postoperative endophthalmitis after combined cataract extraction and iStent inject implantation. <i>Observation.</i> A 70-year-old male with a nuclear sclerotic cataract and primary open-angle glaucoma underwent an uneventful phacoemulsification cataract extraction with implantation of an intraocular lens and an iStent inject trabecular bypass stent. The patient was prescribed a postoperative regimen of ofloxacin 0.3% and prednisolone acetate 1%, 1 drop four times a day each. On postoperative day five, he presented to the emergency room for eye pain and had 4+ mixed cells in the anterior chamber (AC) without hypopyon or vitritis on exam. Prednisolone 1% eye drops were increased from four times a day to every two hours while awake. Overnight, he developed worsening vision and severe eye pain. The next morning, he was found to have increased AC cells, vitritis, and intraretinal hemorrhages and was diagnosed with endophthalmitis. The patient underwent a vitreous tap and intravitreal injections of vancomycin (1 mg/0.1 mL) and amikacin (0.4 mg/0.1 mL). Cultures grew <i>Staphylococcus epidermidis</i>. Lab work-up revealed underlying neutropenia. Visual acuity eventually recovered to 20/20. <i>Conclusion and Importance.</i> This report highlights a case of endophthalmitis associated with placement of the iStent inject. The infection was well-controlled after administration of intravitreal antibiotics without removal of the iStent inject, and visual acuity eventually recovered to 20/20. Surgeons should be aware of endophthalmitis risk following combined iStent inject placement, and good recovery is possible without removal of the implant.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"3132866"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175009/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9523188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retinocytoma Undergoing Retinoblastoma Transformation in an Adult Patient. 成人视网膜细胞瘤视网膜母细胞瘤转化一例。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/8127245
J Navaratnam, R Faber, N Eide, M Lund-Iversen, Ø Garred, F L Munier
{"title":"Retinocytoma Undergoing Retinoblastoma Transformation in an Adult Patient.","authors":"J Navaratnam,&nbsp;R Faber,&nbsp;N Eide,&nbsp;M Lund-Iversen,&nbsp;Ø Garred,&nbsp;F L Munier","doi":"10.1155/2023/8127245","DOIUrl":"https://doi.org/10.1155/2023/8127245","url":null,"abstract":"<p><p>We report a 46-year-old male patient with retinocytoma who presented at the age of 31 asymptomatically. An intraocular retinal mass was incidentally found in his right eye, when he underwent ophthalmological assessment for refractive surgery. This tumor consisted of a calcified sessile basis partially covered by a pedunculated salmon-pink growth. Initially, the tumor was diagnosed as a retinocytoma with clinical suspicion of malignant transformation into retinoblastoma and treated by four sessions of laser photocoagulation. Six and a half years later, the tumor relapsed, and he was treated with a Ruthenium plaque. Following brachytherapy, he had two episodes of right-sided vitreous hemorrhage that spontaneously cleared up, and the remaining finding in the vitreous cavity was interpreted as asteroid hyalosis. He underwent vitrectomy about five years following brachytherapy. The analysis of the vitreous material revealed the presence of inactive vitreous seeds composed of small round blue cells, compatible with a type 2 regression.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"8127245"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10390264/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9980690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bangladeshi Case Series of Bardet-Biedl Syndrome. 孟加拉国Bardet-Biedl综合征病例系列。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/4017010
Fariah Osman, Md Iftekher Iqbal, M Nazrul Islam, Syed Jahangir Kabir
{"title":"Bangladeshi Case Series of Bardet-Biedl Syndrome.","authors":"Fariah Osman,&nbsp;Md Iftekher Iqbal,&nbsp;M Nazrul Islam,&nbsp;Syed Jahangir Kabir","doi":"10.1155/2023/4017010","DOIUrl":"https://doi.org/10.1155/2023/4017010","url":null,"abstract":"<p><p>A rare multisystemic, ciliopathic autosomal recessive disorder called Bardet-Biedl syndrome (BBS) primarily affects children of consanguineous marriages. Both men and women are affected by it. It is characterized by some major and many minor features to aid in the clinical diagnosis and management. Here, we reported two Bangladeshi patients (a 9-year-old girl and 24-year-old male) who were presented with various major and minor features of BBS. Both patients came to us with the symptoms including excessive weight gain, poor vision, and learning disabilities with polydactyly. Our case 1 presented four primary features (retinal degenerations, polydactyly, obesity, and learning deficits) and six secondary features (behavioral abnormality, delayed development, diabetes mellitus, diabetes insipidus, brachydactyly, and LVH), whereas case 2 presented five major criteria (truncal obesity, polydactyly, retinal dystrophy, learning disabilities, and hypogonadism) and six minor criteria (strabismus and cataract, delay in speech, behavioral disorder, developmental delay, brachydactyly and syndactyly, and impaired glucose tolerance test). We diagnosed the cases as BBS. Because there is no specific treatment for BBS, we highlighted the importance of diagnosing it as early as possible so that comprehensive and multidisciplinary care can be offered to prevent avoidable morbidity and mortality.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"4017010"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10122572/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9383861","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Central Retinal Artery Occlusion with Concomitant Intracranial Hemorrhage Secondary to Streptococcus Gordonii Endocarditis. 戈多氏链球菌心内膜炎并发视网膜中央动脉闭塞伴颅内出血。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/9268480
Harshvardhan Chawla, Jonah S Goldblatt, John E Morgan, Bruce A Barron, Aravinda K Rao, Maria A Reinoso
{"title":"Central Retinal Artery Occlusion with Concomitant Intracranial Hemorrhage Secondary to <i>Streptococcus Gordonii</i> Endocarditis.","authors":"Harshvardhan Chawla,&nbsp;Jonah S Goldblatt,&nbsp;John E Morgan,&nbsp;Bruce A Barron,&nbsp;Aravinda K Rao,&nbsp;Maria A Reinoso","doi":"10.1155/2023/9268480","DOIUrl":"https://doi.org/10.1155/2023/9268480","url":null,"abstract":"<p><strong>Purpose: </strong>To report a case of central retinal artery occlusion (CRAO) associated with subacute <i>Streptococcus gordonii</i> endocarditis secondary to a dental infection. <i>Observations</i>. A 27-year-old male presented with acute monocular vision loss in the setting of a stroke and seizure. A fundus exam revealed macular whitening and a cherry-red spot. Edema of the inner retinal layers was confirmed on macular optical coherence tomography, consistent with CRAO. Initial imaging (carotid Doppler, EKG, and transthoracic echocardiography) and a comprehensive laboratory workup did not reveal an etiology for the stroke or vision loss. Brain magnetic resonance imaging showed T1 hyperintensity with surrounding edema, which prompted a workup for possible septic emboli versus occult malignancy. Subsequent blood cultures led to the detection and diagnosis of <i>Streptococcus gordonii</i> endocarditis. It was subsequently revealed that the patient had self-extracted his molar two months prior to the onset of symptoms.</p><p><strong>Conclusions: </strong>Endocarditis has been associated with Roth spots and inflammatory findings in the posterior segment. However, CRAO caused by vegetal septic embolism is rare. To our knowledge, this represents the first reported case of endocarditic CRAO with <i>Streptococcus gordonii</i> confirmed as the causative microbe. Retinal vascular occlusion in a young patient with no distinct risk factors should prompt a comprehensive dental history and infectious workup, with consideration given to early transesophageal echocardiography.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"9268480"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10195172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9503301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case Report of Management of Medulloepithelioma of the Ciliary Body and Iris without Recurrence over an Observation Period of Twenty Years. 睫状体及虹膜髓样上皮瘤治疗20年无复发1例。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/1508341
N Eide, J Navaratnam, P Jebsen
{"title":"A Case Report of Management of Medulloepithelioma of the Ciliary Body and Iris without Recurrence over an Observation Period of Twenty Years.","authors":"N Eide,&nbsp;J Navaratnam,&nbsp;P Jebsen","doi":"10.1155/2023/1508341","DOIUrl":"https://doi.org/10.1155/2023/1508341","url":null,"abstract":"<p><p>Intraocular medulloepithelioma is a rare embryonal tumor that is believed to arise from the epithelium of the medullary tube. We report a 37-year-old female with medulloepithelioma presented at the age of 17 with a one-month history of left-sided visual deterioration and visible iris lesion. Birth history and medical and family histories were insignificant. The left eye revealed a vascularized iris mass. Further examination revealed a grey-white ciliary body mass and a subluxated lens with best-corrected visual acuity (BCVA) of 0.5. The patient underwent partial lamellar corneo-sclerouvectomy. The histological and electron microscopic findings revealed medulloepithelioma. To reduce the risk of recurrence of the probable malignant tumor, she was treated with Ruthenium plaque therapy about six weeks following surgical removal. Pars plana vitrectomy and lensectomy with laser photocoagulation of the peripheral retina were performed at the removal of the brachytherapy plaque. She regained her BCVA of 1.0 in her left eye 3.5 months following pars plana vitrectomy. At 20-year follow-up, no tumor recurrence was seen and her BCVA remained 1.0.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"1508341"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897911/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10666417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic Intracranial Hypertension Papillopathy due to Hormonal Changes during Pregnancy. 妊娠期激素变化引起的特发性颅内高压乳头病。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/6688445
Marco Mafrici, Francesca Tona, Serena Fragiotta, Umberto Lorenzi, Lorenzo Gitto, Laura Toscani
{"title":"Idiopathic Intracranial Hypertension Papillopathy due to Hormonal Changes during Pregnancy.","authors":"Marco Mafrici,&nbsp;Francesca Tona,&nbsp;Serena Fragiotta,&nbsp;Umberto Lorenzi,&nbsp;Lorenzo Gitto,&nbsp;Laura Toscani","doi":"10.1155/2023/6688445","DOIUrl":"https://doi.org/10.1155/2023/6688445","url":null,"abstract":"<p><strong>Background: </strong>The underlying mechanisms of papilledema associated with intracranial hypertension remain unclear. A case of bilateral papillary edema in a patient with chronic idiopathic intracranial hypertension who was asymptomatic during her two pregnancies is reported. <i>Case Presentation</i>. A 19-year-old Caucasian female, in her third month of pregnancy, complained of difficulties with close reading. The patient's visual acuity was 20/20 on the Snellen chart and improved with a 0.50 D correction in both eyes. Near vision and slit lamp examinations revealed normal findings bilaterally. However, a fundus examination showed bilateral papillary edema without evidence of hemorrhages or neovascularization. Blood tests were unremarkable, except for a slight increase in C-reactive protein levels. The patient had a prepregnancy weight of 63 kilograms, with a BMI of 24.91 kg/m<sup>2</sup>. Magnetic resonance imaging of the brain revealed features consistent with chronic idiopathic intracranial hypertension, which resolved after delivery. Two and a half years later, during a subsequent pregnancy, the patient experienced a recurrence of bilateral papillary edema due to the IIH. It was managed similarly as the first occurrence, resulting in bilateral anatomical and functional recovery. Recent research revealed that, during pregnancy, hormones interact with the central nervous system, leading to an increase in the size of neurons which could potentially result in intracranial hypertension.</p><p><strong>Conclusions: </strong>The influence of hormonal fluctuations during pregnancy on the development of transient central nervous system abnormalities in individuals with chronic intracranial hypertension, leading to papillary edema, remains a matter of debate.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"6688445"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10353893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10202723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Citrobacter koseri: A Cause of Silicone Oil Related Endophthalmitis after Post Pars Plana Vitrectomy. 玻璃体切除术后硅油相关性眼内炎的原因之一。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/3494521
Luigi Sborgia, Valeria Albano, Giancarlo Sborgia, Francesco Boscia, Giovanni Alessio
{"title":"Citrobacter koseri: A Cause of Silicone Oil Related Endophthalmitis after Post Pars Plana Vitrectomy.","authors":"Luigi Sborgia,&nbsp;Valeria Albano,&nbsp;Giancarlo Sborgia,&nbsp;Francesco Boscia,&nbsp;Giovanni Alessio","doi":"10.1155/2023/3494521","DOIUrl":"https://doi.org/10.1155/2023/3494521","url":null,"abstract":"<p><strong>Purpose: </strong>We present a rare case of <i>Citrobacter koseri</i> culture-positive endophthalmitis in a postvitrectomy silicone oil-filled eye. <i>Case report.</i> A 64-year-old male patient presented to our ophthalmology emergency room with representative symptoms of acute endophthalmitis. He underwent a plana vitrectomy oil-filled tamponade previously. Preoperative and postoperative findings of the case were reported.</p><p><strong>Results: </strong>Culture tests of aqueous, silicone oil, and vitreous taps were positive for <i>Citrobacter koseri</i>.</p><p><strong>Conclusions: </strong>Culture-positive endophthalmitis in a silicone oil-filled eye has very rarely been in the literature. The described cases were caused by acute inflammatory reactions to silicone oil and were culture-negative. The postvitrectomy culture-positive endophthalmitis caused by <i>Citrobacter</i> is a very rare condition, and its management is not so smooth. Approaching with silicone oil removal, intraoperative intravitreal antibiotic injection, and silicone oil reinjection was performed in our case with good outcomes.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"3494521"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10039805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9204610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Intravitreal Dexamethasone Implant in Autoimmune Retinopathy. 自身免疫性视网膜病变玻璃体内地塞米松植入
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/5670538
Fernando Longhi Bordin, Carolina da Silva Mengue, Manuel Augusto Pereira Vilela
{"title":"Intravitreal Dexamethasone Implant in Autoimmune Retinopathy.","authors":"Fernando Longhi Bordin,&nbsp;Carolina da Silva Mengue,&nbsp;Manuel Augusto Pereira Vilela","doi":"10.1155/2023/5670538","DOIUrl":"https://doi.org/10.1155/2023/5670538","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the results of an intravitreal dexamethasone implant in managing autoimmune retinopathy (AIR).</p><p><strong>Methods: </strong>Two patients affected by AIR underwent intravitreal dexamethasone implantation and were followed by ocular coherence tomography, visual fields, and electroretinography.</p><p><strong>Results: </strong>The patients showed an interruption of the functional losses and remained stable with semestral injections.</p><p><strong>Conclusion: </strong>AIR is a complex condition with no standard treatment. The use of dexamethasone could be a valid option.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"5670538"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10081906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9336703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Langerhans Cell Histiocytosis of the Uvea with a Ciliochoroidal Mass: A Case Report of Management with Systemic Therapy. 伴有纤毛脉络膜肿块的葡萄膜朗格汉斯细胞组织细胞增多症:采用全身治疗的一例报告。
IF 0.9
Case Reports in Ophthalmological Medicine Pub Date : 2023-01-01 DOI: 10.1155/2023/5543131
Fariba Ghassemi, Hamid Riazi-Esfahani, Nazanin Ebrahimiadib, Abdulrahim Amini, Zahra Mahdizad
{"title":"Langerhans Cell Histiocytosis of the Uvea with a Ciliochoroidal Mass: A Case Report of Management with Systemic Therapy.","authors":"Fariba Ghassemi,&nbsp;Hamid Riazi-Esfahani,&nbsp;Nazanin Ebrahimiadib,&nbsp;Abdulrahim Amini,&nbsp;Zahra Mahdizad","doi":"10.1155/2023/5543131","DOIUrl":"https://doi.org/10.1155/2023/5543131","url":null,"abstract":"<p><strong>Background: </strong>This study is aimed at exploring a case of choroidal Langerhans cell histiocytosis (LCH) successfully treated with systemic corticosteroid and immunosuppressant. <i>Case presentation</i>. A 24-year-old man with known multisystem LCH developed loss of vision, ocular pain, conjunctival injection, panuveitis, and a ciliochoroidal mass. After receiving an intravenous methylprednisolone pulse, oral high-dose corticosteroids, and methotrexate, the mass resolved quickly and completely without flare-ups during 6 months of follow-up.</p><p><strong>Conclusions: </strong>Intraocular involvement of LCH is rare and can present with or without a history of multisystemic disease. The diagnosis is challenging, and the standard treatment is not established. Systemic anti-inflammatory and immunosuppressive therapy could be an effective treatment, as the LCH itself contains an essential element of inflammation and the symptoms may be mainly inflammatory.</p>","PeriodicalId":9603,"journal":{"name":"Case Reports in Ophthalmological Medicine","volume":"2023 ","pages":"5543131"},"PeriodicalIF":0.9,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10491478/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10220070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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