CardioVascular and Interventional Radiology最新文献

{"title":"Multistage Preclinical Evaluation of MRI-Guided Stenting for Coarctation of the Aorta using in vitro and Porcine Models.","authors":"Denis Gholami Bajestani, C Martin Reich, Jan Birkigt, Christina Mulik, Johannes Kauffold, Haukur Lindberg Sigmarsson, Thies Jochimsen, Bernhard Sattler, Osama Sabri, Michael Steinmetz, Andreas Melzer","doi":"10.1007/s00270-026-04642-w","DOIUrl":"https://doi.org/10.1007/s00270-026-04642-w","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluated the technical and procedural feasibility of MRI-guided stent implantation for CoA using a structured multistage preclinical evaluation protocol.</p><p><strong>Materials and methods: </strong>A commercially available MR Conditional guidewire and dedicated research prototypes comprising nitinol stents, delivery systems, and balloon catheters were assessed in a three-stage protocol. Device visibility was evaluated in a standardized water phantom at 1.5 T and 3.0 T. In a polymer-based CoA vessel phantom, 10 stent implantations were performed by novices (n = 6) and experts (n = 4), with four separate expert-led balloon dilatations. MRI-guided stent implantation was subsequently performed in five porcine models.</p><p><strong>Results: </strong>All devices were visible at both field strengths, with lateral artifact widths of 5.3-7.8 mm for the guidewire, 20.9-38.5 mm for the stent delivery system, 13.1-19.9 mm for the expanded stents, and 17.4-30.5 mm for the balloon catheter. Phantom stenting duration was 10.2 ± 7.2 mins for novices and 6.2 ± 2.7 mins for experts. MRI-guided stent implantation was successfully performed in all five animals, with a mean duration of 13.6 ± 7.5 mins. In one animal, balloon post-dilatation was additionally performed as a procedural proof of concept.</p><p><strong>Conclusion: </strong>MRI-guided stent implantation for CoA is feasible within a structured multistage preclinical evaluation protocol and supports further clinical translation of radiation-free endovascular treatment.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149214959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Cholangioscopy-Guided Cryoadhesion Removal of an Endobiliary Polyp.","authors":"Flavio Scavone Stefanini, Thiago Franchi Nunes, Vinicius Adami Vayego Fornazari, Belarmino Gonçalves","doi":"10.1007/s00270-026-04649-3","DOIUrl":"https://doi.org/10.1007/s00270-026-04649-3","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Balloon-Occlusion Versus End-Hole Transarterial Chemoembolization for Hepatocellular Carcinoma: A Systematic Review and Meta-analysis.","authors":"Salvatore Tumolo, Afonso Quelhas Fonseca, Vincenzo Vingiani, Tiago Bilhim, Hüseyin Saygin Tuna","doi":"10.1007/s00270-026-04645-7","DOIUrl":"https://doi.org/10.1007/s00270-026-04645-7","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the efficacy and safety of balloon-occluded transarterial chemoembolization (B-TACE) compared with conventional (cTACE) and drug-eluting-bead transarterial chemoembolization (DEB-TACE) in patients with hepatocellular carcinoma.</p><p><strong>Materials and methods: </strong>A systematic review and meta-analysis was conducted following PRISMA guidelines and registered in PROSPERO. PubMed, Scopus, and the Cochrane Central Register of Controlled Trials were searched to 8 February 2026 for randomized and observational studies comparing B-TACE with cTACE or DEB-TACE. Tumor response (mRECIST), overall survival, and adverse events were pooled using random-effects models; risk of bias was assessed with established tools.</p><p><strong>Results: </strong>Nine studies (one randomized, eight observational; 1534 patients) were included. Complete response, objective response, disease control, and progressive disease did not differ significantly between groups, with moderate-to-substantial heterogeneity. Baseline tumors were larger in the balloon-occluded group (mean difference 4.34 mm; 95% CI 1.18- 7.50; p = 0.014). Exploratory study-level analyses suggested greater relative B-TACE effects with larger tumors, particularly for complete response and disease control.Overall survival favored B-TACE in the two studies with extractable hazard ratios (HR 0.41; 95% CI 0.23 to 0.73; p = 0.002). Post-treatment liver enzymes, bilirubin, fever, and post-embolization syndrome did not differ significantly.</p><p><strong>Conclusion: </strong>No statistically significant differences in imaging response or safety were observed between intervention and comparator groups, while B-TACE was associated with a signal toward improved overall survival despite larger baseline tumors. Exploratory findings suggested that larger tumor size may be associated with a greater relative B-TACE effect. Given the limited evidence, these findings require confirmation in randomized controlled trials.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Achilles and the Tortoise in the Kidney: Thermal Ablation Takes One More Step Towards Surgery for Cystic Renal Masses.","authors":"Marco Calandri","doi":"10.1007/s00270-026-04634-w","DOIUrl":"https://doi.org/10.1007/s00270-026-04634-w","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating Histotripsy into Chemoimmunotherapy for Oligometastatic Recurrent Extrahepatic Cholangiocarcinoma: Case Report.","authors":"Andrew Guzowski, Peter Rudnick","doi":"10.1007/s00270-026-04643-9","DOIUrl":"https://doi.org/10.1007/s00270-026-04643-9","url":null,"abstract":"<p><p>The management of advanced, recurrent extrahepatic cholangiocarcinoma has shifted toward prolonged systemic therapy including immune checkpoint inhibition. Incorporating local treatment for oligometastatic or oligoprogressive disease without interrupting systemic therapy remains challenging. Conventional liver-directed therapies frequently require a chemotherapy break. Histotripsy is a noninvasive, non-thermal, non-ionizing modality that permits continuation of systemic therapy. This case presents a 71-year-old woman with recurrent extrahepatic cholangiocarcinoma who developed multifocal hepatic metastases while receiving gemcitabine and durvalumab. She was deemed not a candidate for further radiation therapy or other locoregional therapies; thus, nine of ten hepatic lesions were treated with histotripsy in a single session. This case highlights the possibility of integrating histotripsy with chemoimmunotherapy by providing short-term local control of oligometastatic progression without the need to interrupt systemic treatment.Level of Evidence: Level 4, Case Report.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Paediatric Interventional Radiology: Growing Up and Looking Ahead.","authors":"Premal A Patel, Anne Marie Cahill","doi":"10.1007/s00270-026-04652-8","DOIUrl":"https://doi.org/10.1007/s00270-026-04652-8","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simulation Training in IR: Retaining Command of the Jagged Frontier.","authors":"Paul M Gibbs","doi":"10.1007/s00270-026-04654-6","DOIUrl":"https://doi.org/10.1007/s00270-026-04654-6","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149191455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interventional Radiology in Undergraduate Medical Education: A Kern's Framework Approach.","authors":"Iranna Mallappa Hittalamani","doi":"10.1007/s00270-026-04637-7","DOIUrl":"https://doi.org/10.1007/s00270-026-04637-7","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149179050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endovascular Therapy for Femoropopliteal Artery Lesions Involving the Popliteal Artery: 1-Year Outcomes from a Real-World Multicenter Registry.","authors":"Leixin Li, Youpeng Zhu, Wenbo Yang, Ye Du, Qiong Song, Tingyu Wang, Xinyuan Wang, Chunbo Li, Zhimin Chen, Zibo Feng","doi":"10.1007/s00270-026-04638-6","DOIUrl":"https://doi.org/10.1007/s00270-026-04638-6","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate real-world outcomes of endovascular treatment for femoropopliteal lesions involving the popliteal artery and, in a post-hoc exploratory analysis, assess whether anatomical location (P3 vs. P1/P2 segments) was associated with clinical decision-making and prognosis.</p><p><strong>Materials and methods: </strong>We conducted a retrospective, post-hoc analysis of 946 patients from the prospective PROMISING registry. For this exploratory analysis, patients were stratified according to distal (P3) versus proximal/mid (P1/P2) popliteal artery involvement. Predictors of stent implantation and clinical decision pathways were compared across groups.</p><p><strong>Results: </strong>Overall procedural success was 98.5%, and the 12-month freedom from major adverse events (MAE), defined as a composite of all-cause mortality, major amputation, or clinically driven target lesion revascularization, was 80.1%. Multivariable analysis indicated P3 involvement independently predicted reduced stent implantation (OR 0.66, 95% CI 0.46-0.95, p = 0.027). For vessel preparation, the P3 group more frequently utilized plain old balloon angioplasty (POBA, 67.8% vs. 54.8%, p < 0.001) rather than directional atherectomy or specialty balloons. Despite a lower stent implantation rate and greater use of POBA, 12-month freedom from MAE was comparable between the P3 and P1/P2 groups (78.0% vs. 81.2%, p = 0.481).</p><p><strong>Conclusion: </strong>In this post-hoc analysis of real-world registry data, popliteal lesion location was associated with differences in operator treatment strategies. P3 involvement was associated with less frequent stent implantation and greater use of plain balloon angioplasty, while 1-year clinical outcomes were comparable between the P3 and P1/P2 groups. These exploratory findings require external validation before they can be used to inform clinical treatment strategies.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier NCT04826705 (Registered on March 29, 2021).</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149178734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-Line Thrombectomy for Acute Intracranial Atherosclerotic Stenosis-Related Vertebrobasilar Artery Occlusion: Stent Retriever-Based Versus Contact Aspiration Thrombectomy Strategies.","authors":"Bo Huang, Guangdong Lu, Yuan Ma, Xian Xie, Linbo Zhao, Yuezhou Cao, Zhenyu Jia, Penghua Lv, Sheng Liu, Haibin Shi","doi":"10.1007/s00270-026-04644-8","DOIUrl":"https://doi.org/10.1007/s00270-026-04644-8","url":null,"abstract":"<p><strong>Purpose: </strong>To compare procedural and clinical outcomes of first-line contact aspiration thrombectomy (CAT) versus a stent retriever-based strategy in acute intracranial atherosclerotic stenosis (ICAS)-related vertebrobasilar artery occlusion (VBAO).</p><p><strong>Materials and methods: </strong>This retrospective two-center study included consecutive patients with acute ICAS-related VBAO treated between 2019 and 2024. Patients were classified by first-line strategy as CAT or an SRT-based strategy comprising stent retriever thrombectomy alone or with aspiration assistance. Primary outcomes were first-pass recanalization (FPR; modified Thrombolysis in Cerebral Infarction grade ≥ 2b after one device pass) and 90-day favorable functional outcome (modified Rankin Scale score 0-3). Multivariable regression was used for outcome comparisons, with inverse probability weighting (IPW) as a sensitivity analysis.</p><p><strong>Results: </strong>Among 129 patients, 38 received CAT and 91 received an SRT-based strategy. FPR was higher with the SRT-based strategy than with CAT (74.7% vs. 52.6%; adjusted odds ratio [aOR], 2.66; 95% CI, 1.15-6.16; p = 0.022). The 90-day favorable outcome did not differ significantly (48.4% vs. 36.8%; aOR, 1.69; 95% CI, 0.71-4.02; p = 0.235). In the primary adjusted analysis, the SRT-based strategy was associated with lower 90-day mortality (19.8% vs. 34.2%; aOR, 0.37; 95% CI, 0.15-0.96; p = 0.041), fewer strategy switches (1.1% vs. 34.2%; p < 0.001), and shorter puncture-to-recanalization time (63.0 vs. 73.5 min; p = 0.003). IPW supported these procedural advantages, whereas clinical outcome differences were nonsignificant.</p><p><strong>Conclusion: </strong>In acute ICAS-related VBAO, a first-line SRT-based strategy was associated with better procedural performance than CAT, including higher first-pass recanalization, fewer strategy switches, and shorter puncture-to-recanalization time.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":3.4,"publicationDate":"2026-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149134952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}