David-Dimitris Chlorogiannis, Bedros Taslakian, Osman Ahmed, Attur Mukundan, Ali Guermazi, Anish Ghodadra, Venkatesh P Krishnasamy, Wali Badar, Yan Epelboym
{"title":"Key Osteoarthritis Biomarkers: What Interventional Radiologists Performing Genicular Artery Embolization Need to Know.","authors":"David-Dimitris Chlorogiannis, Bedros Taslakian, Osman Ahmed, Attur Mukundan, Ali Guermazi, Anish Ghodadra, Venkatesh P Krishnasamy, Wali Badar, Yan Epelboym","doi":"10.1007/s00270-025-04045-3","DOIUrl":"https://doi.org/10.1007/s00270-025-04045-3","url":null,"abstract":"<p><p>Knee osteoarthritis (OA) is a major cause of pain and disability. Genicular artery embolization (GAE) is a promising alternative for patients unresponsive to conservative treatment or unsuitable for total knee replacement. GAE may alleviate knee pain by reducing synovitis and by causing ischemia to pathologic knee nerves. However, outcomes vary based on baseline MRI and radiographic findings, making patient selection challenging. Recently, reduction in synovitis on contrast-enhanced MRI has been associated with pain relief post-GAE. Novel OA phenotypes (inflammatory, cartilage, bone, and atrophic) can aid in patient selection by using imaging and molecular biomarkers. Moreover, imaging features such as cartilage defects, bone marrow lesions, and synovitis may predict symptomatic outcomes. This review explores OA pathophysiology, focusing on radiographic, biochemical, and imaging biomarkers in evaluating GAE for knee OA treatment.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118966","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Howell Fu, Alex Gordon-Weeks, Rachel Kerr, Zahi Qamhawi, Daniel Kearns, Andrew Macdonald
{"title":"Iatrogenic Subcapsular Haematoma Leads to 151% Growth of Future Liver Remnant.","authors":"Howell Fu, Alex Gordon-Weeks, Rachel Kerr, Zahi Qamhawi, Daniel Kearns, Andrew Macdonald","doi":"10.1007/s00270-025-04068-w","DOIUrl":"https://doi.org/10.1007/s00270-025-04068-w","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N Tolboom, T J Snijders, E P A Vonken, I C van der Schaaf, T Seute, A J A T Braat
{"title":"Intra-arterial Administration of Radiopharmaceuticals in Neuro-Oncology; New Improvement for [<sup>131</sup>I]-Phenylalanine in High-Grade Gliomas?","authors":"N Tolboom, T J Snijders, E P A Vonken, I C van der Schaaf, T Seute, A J A T Braat","doi":"10.1007/s00270-025-04052-4","DOIUrl":"https://doi.org/10.1007/s00270-025-04052-4","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cervical Intranodal Lymphangiogram in Pediatrics; Technique, Safety, and Clinical Applications.","authors":"Mohamed M Shahin, Kumar K Shashi, Raja Shaikh","doi":"10.1007/s00270-025-04050-6","DOIUrl":"https://doi.org/10.1007/s00270-025-04050-6","url":null,"abstract":"<p><strong>Purpose: </strong>This paper introduces a novel technique, cervical lymphangiogram, involving intranodal lymphangiogram through cervical lymph nodes. We will discuss our preliminary experience regarding the technique, safety, and applications, offering a promising approach to addressing central conducting duct opacification challenges.</p><p><strong>Material and methods: </strong>This retrospective study was IRB exempt. All patients failed conservative management for treatment of chylous effusion. Patients who underwent cervical lymphangiogram as either diagnostic or therapeutic process were included. All patients were imaged with magnetic resonance lymphangiogram (MRL) followed by fluoroscopic inguinal intranodal lymphangiogram with failure to opacify thoracic duct or source of chylous effusion. Both, intranodal lymphangiograms and MRL were performed using water-soluble contrast due to the risk of paradoxical emboli given either suspected or confirmed right-to-left shunts.</p><p><strong>Results: </strong>Cervical lymphangiogram was performed on 7 patients with ages ranging from 40 days to 8 years. Etiology included unilateral or bilateral chylous pleural effusions. Technical success (defined as opacification of thoracic duct depicting its anatomy, revealing the underlying disorder, either a leak or congenital anomaly) rate was 100%. Clinical success (defined by resolution of symptoms) rate was 100% in patients that showed evidence of leak and underwent glue embolization (6 out of 7 patients). No technique-related complications incurred in any patients. The mean follow-up duration to exclude recurrence and watch for complications was 150 days.</p><p><strong>Conclusion: </strong>Cervical lymphangiogram is a promising and safe technique to evaluate central conducting ducts where inguinal lymphangiograms (intranodal or MRL) have failed to demonstrate the same.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144118950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation-Free Cannulation of the Uterine Artery during Fibroid Embolization Using Fiberoptic Real Shape Technology.","authors":"Timo A Auer, Federico Collettini","doi":"10.1007/s00270-025-04054-2","DOIUrl":"https://doi.org/10.1007/s00270-025-04054-2","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association Between Geriatric Nutritional Risk Index and Discharge Outcome after Elective Thoracic Endovascular Aortic Repair.","authors":"Takafumi Ouchi, Noriyuki Kato, Hiroaki Kato, Takatoshi Higashigawa, Hisato Ito, Ken Nakajima, Shuji Chino, Toshiya Tokui, Kensuke Oue, Toru Mizumoto, Yasutaka Ichikawa, Hajime Sakuma","doi":"10.1007/s00270-025-04066-y","DOIUrl":"https://doi.org/10.1007/s00270-025-04066-y","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the utility of the Geriatric Nutritional Risk Index (GNRI) in predicting nonhome discharge (NHD) and delayed discharge after elective thoracic endovascular aortic repair (TEVAR).</p><p><strong>Methods: </strong>The study population included patients undergoing elective simple TEVAR for intact thoracic aortic aneurysm or subacute or chronic aortic dissection between January 2009 and December 2022 and not experiencing neurological complications or re-interventions during hospitalization. The primary outcome measure was NHD and significantly delayed discharge. GNRI was calculated using the following equation: GNRI = 14.89 × serum albumin (g/dL) + 41.7 × (body mass index [kg/m<sup>2</sup>] / 22). A univariable logistic regression model was used to determine the odds ratio for GNRI. The predictive performance of GNRI was evaluated using the area under the receiver operating characteristic curve (AUC).</p><p><strong>Results: </strong>A total of 229 patients were analyzed and the overall rate of the primary outcome was 5.7% (NHD, n = 6; delayed discharge, n = 10; both, n = 3). Patients with the primary outcome were more likely to have a lower GNRI (98 vs 103; P = .01) than those without. The logistic regression model showed that a high GNRI was protective against NHD (odds ratio, 0.38; 95% confidence interval, 0.18-0.76; P = .008). The AUC for GNRI was 0.710 (95% confidence interval, 0.602-0.821). The sensitivity, specificity, positive predictive value, and negative predictive value of GNRI < 92 were 23%, 89%, 11%, and 95%, respectively.</p><p><strong>Conclusions: </strong>Preoperative evaluation of GNRI may be useful in predicting NHD and delayed discharge.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Invited Commentary on the Embolic Effect of Different Cyanoacrylates: Radiological and Histological Comparison in an in vivo Rabbit Renal-Artery Model.","authors":"Atsushi Saiga","doi":"10.1007/s00270-025-04047-1","DOIUrl":"https://doi.org/10.1007/s00270-025-04047-1","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Goran Mitric, Ravi Natvar Mistry, Azhar Toodayan, Christopher Ellis, Maria Gabriela Matta
{"title":"Percutaneous Vegetectomy for Fungal Tricuspid Valve Endocarditis: A Minimally Invasive Approach in A Patient on Veno-Venous ECMO.","authors":"Goran Mitric, Ravi Natvar Mistry, Azhar Toodayan, Christopher Ellis, Maria Gabriela Matta","doi":"10.1007/s00270-025-04076-w","DOIUrl":"https://doi.org/10.1007/s00270-025-04076-w","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute Toxic Liver Cirrhosis with Intrahepatic Portal Vein Aneurysm Treated with Transjugular Intrahepatic Portosystemic Shunt.","authors":"K Ramdhani, M Georgiades, M Pech","doi":"10.1007/s00270-025-04057-z","DOIUrl":"https://doi.org/10.1007/s00270-025-04057-z","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Cheolho Kwon, Jae Hwan Lee, Kun Yung Kim, Chong-Ho Lee, Chang Jin Yoon, Sung-Hwan Yoon, Young-Min Han, Minuk Kim
{"title":"Bioresorbable Gelatin Microspheres for Temporary Transarterial Embolization: Feasibility Study in Porcine Kidney Model.","authors":"Cheolho Kwon, Jae Hwan Lee, Kun Yung Kim, Chong-Ho Lee, Chang Jin Yoon, Sung-Hwan Yoon, Young-Min Han, Minuk Kim","doi":"10.1007/s00270-025-04062-2","DOIUrl":"https://doi.org/10.1007/s00270-025-04062-2","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the in vivo characteristics, degradation profile, and feasibility of a bioresorbable gelatin microsphere (R-GM) for controlled, temporary embolization in a porcine kidney model.</p><p><strong>Materials and methods: </strong>Six male farm pigs underwent transarterial embolization of the artery to the left kidney upper pole (LKUP) and to the right kidney upper pole (RKUP) using 100-300-µm-sized tris-acryl gelatin microsphere (T-GM) and R-GM, respectively. Follow-up angiography was performed in 2 h, 2 days, 1 week, 3 weeks, and 16 weeks to assess the presence of recanalization of the embolized arteries. Each pig was killed at each time point, and histopathologic analysis was performed to evaluate the presence of embolic agents, inflammatory reaction, and degree of tissue damage of the embolized renal segment.</p><p><strong>Results: </strong>On 2 h post-angiogram, LKUP was occluded, and RKUP was fully recanalized in all pigs. Parenchymal staining of the RKUP area was normalized at 2 h post-embolization and maintained until the 16-week follow-up. No R-GM or fragments were found in any specimens except for 2 days, but tris-acryl microspheres were observed in tissues with infarction with inflammatory changes until the 16-week follow-up. The levels of macrophages, giant cells, neovascularization, and fibrosis were higher in the LKUP compared to the RKUP at 1 week to 16 weeks (all, p < 0.05). The LKUP had a higher infarct area up to 97.17 ± 0.64% at 1 week compared to the RKUP, which had no infarction (0 ± 0%).</p><p><strong>Conclusion: </strong>Temporary transarterial embolization using R-GM was feasible in vivo, achieving temporary occlusion followed by complete recanalization of the embolized vessel and minimal tissue damage.</p><p><strong>Levels of evidence: </strong>No levels of Evidence (Experimental study).</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}