{"title":"End of the Long Road or First Chapter of a New Story: Clinical Reflections on the COLLISION Trial.","authors":"Philippe L Pereira, Asmund A Fretland","doi":"10.1007/s00270-025-04110-x","DOIUrl":"https://doi.org/10.1007/s00270-025-04110-x","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Arian Taheri Amin, L M Wilms, N Steinfort, D Weiss, K Jannusch, P Freyhardt, M Leist, C Nolte-Ernsting, M Katoh, A Bücker, F Ziayee, P Minko
{"title":"Multicentric Angiographic Assessment of the Branching Patterns and Anastomotic Network of the Genicular Arteries, with Implications for Genicular Artery Embolization.","authors":"Arian Taheri Amin, L M Wilms, N Steinfort, D Weiss, K Jannusch, P Freyhardt, M Leist, C Nolte-Ernsting, M Katoh, A Bücker, F Ziayee, P Minko","doi":"10.1007/s00270-025-04106-7","DOIUrl":"https://doi.org/10.1007/s00270-025-04106-7","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the anatomy of the genicular arteries and their anastomoses based on intraprocedural digital subtraction angiography (DSA).</p><p><strong>Materials and methods: </strong>This retrospective, multi-center study reviewed patients who underwent genicular artery embolization (GAE) between January 2019 and December 2023. DSA images were analyzed to assess the anatomy of the genicular arteries and their anastomoses.</p><p><strong>Results: </strong>A total of 393 GAEs in 358 patients with minimal to severe knee osteoarthrosis (OA; Kellgren/Lawrence Grade I-IV) were analysed. Anastomoses between genicular branches were observed in all patients. In the medial compartment, anastomoses were identified between the descending genicular artery (DGA) and superior medial genicular artery (SMGA) in 158 GAEs (40%), the DGA and inferior medial genicular artery (IMGA) in 132 GAEs (34%), and the SMGA and IMGA in 64 GAEs (16%). In the lateral compartment, anastomoses were observed between the superior lateral genicular artery (SLGA) and inferior lateral genicular artery (ILGA) in 192 GAEs (49%), the ILGA and anterior tibial recurrent artery (ARTA) in 152 GAEs (39%), and between the SLGA, ILGA and ARTA in 91 GAEs (23%). Anastomoses between the medial and lateral compartments were identified between the DGA and SLGA in 59 GAEs (15%), the DGA and ILGA in 87 GAEs (22%), and the IMGA and ILGA in 94 GAEs (24%). The mean vessel diameter of the anastomoses ranged from 0.2 to 1.1 mm.</p><p><strong>Conclusion: </strong>Anastomoses between genicular arteries are frequent and extensive, with diameters exceeding the sizes of particles (100-300 μm) and microcatheters (1.7-2.4F) commonly used in GAE.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Howard Dabbous, Sandra Gad, Michael Mohnasky, Alex Villalobos, David Brandon, Minzhi Xing, Nima Kokabi
{"title":"Tumor Dose as an Oncologic Predictor of Outcome in Patients with HCC Treated with Resin Y90 Microspheres.","authors":"Howard Dabbous, Sandra Gad, Michael Mohnasky, Alex Villalobos, David Brandon, Minzhi Xing, Nima Kokabi","doi":"10.1007/s00270-025-04113-8","DOIUrl":"https://doi.org/10.1007/s00270-025-04113-8","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate tumor dose (TD) as a predictor of oncological outcomes in patients with hepatocellular carcinoma (HCC) treated with resin Y90 radioembolization (RE), and to evaluate non-tumoral liver dose (NTLD) as a predictor of treatment-related toxicity.</p><p><strong>Methods: </strong>A single-center retrospective review of treatment-naïve HCC patients who underwent resin-based Y90 between 2019 and 2022 was conducted. Baseline demographics, clinical history, and adverse events per CTCAE v5.0 were analyzed. Baseline imaging and post-treatment imaging were also evaluated using Response per Modified Response Evaluation Criteria in Solid Tumors (mRECIST) for tumor response.</p><p><strong>Results: </strong>78 patients (mean age:66.7 years) with 91 tumors underwent Y90-RE, with a median follow-up period of 28.3 months; 23 received lobar Y90-RE, while 55 patients received segmentectomies. Mean TD for the entire cohort was 336.6 ± 291.9 Gy. Mean TD was significantly higher in segmental Y90-RE (424.3 Gy) vs lobar Y90-RE (203.7 Gy) (p < 0.001). At 3 months, 98% of segmentectomy and 72% of lobar patients achieved an objective response (OR), with 90% and 40% achieving complete response (CR), respectively. At 6 months, 97% and 94% of segmentectomy patients achieved OR and CR, compared to 84% and 68% in lobar patients. Mean tumor dose > 250 Gy predicted prolonged overall and progression free survival. A mean NTLD dose of 103 Gy predicted grade 3 + adverse events in lobar treatments.</p><p><strong>Conclusion: </strong>In patients with HCC treated with resin-based Y90-RE, personalized dosimetry is a key factor in ensuring favorable oncological outcomes. Level of evidence Level 3b, retrospective cohort study.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zahi Qamhawi, Simon Braithwaite, Rezhwan Ahmed, Daniel Kearns, Emma Wilton, Andrew Wigham
{"title":"Mechanical Thrombectomy for the Treatment of Iliofemoral Deep Venous Thrombosis using the ClotTriever System: A Single-Centre Experience.","authors":"Zahi Qamhawi, Simon Braithwaite, Rezhwan Ahmed, Daniel Kearns, Emma Wilton, Andrew Wigham","doi":"10.1007/s00270-025-04112-9","DOIUrl":"https://doi.org/10.1007/s00270-025-04112-9","url":null,"abstract":"<p><strong>Purpose: </strong>Iliofemoral deep venous thrombosis (DVT) is a significant cause of morbidity, with up to 50% of patients developing post-thrombotic syndrome (PTS). Mechanical thrombectomy (MT) has been proposed to restore early vessel patency and reduce PTS risk. This study evaluated outcomes of patients with iliofemoral DVT treated using Inari's ClotTriever system.</p><p><strong>Materials and methods: </strong>A retrospective review was conducted of consecutive patients with iliofemoral DVT treated with ClotTriever. Technical success (defined as ≥ 75% thrombus removal and restoration of vein patency) and patency rates were assessed up to 12 months. Primary patency was defined as maintained patency without reintervention; assisted primary patency included reintervention without re-occlusion, and secondary patency referred to restored patency after occlusion. PTS was assessed using the Villalta score at a median follow-up of 4 months. Hospitalisation length, complications, and 30-day mortality were also recorded.</p><p><strong>Results: </strong>Ninety limbs in 81 patients were treated. Thrombus chronicity was acute (30.0%), subacute (35.6%), and chronic (34.4%). Technical success was achieved in 98.9% of limbs. Primary patency rates at 6 and 12 months were 78.8% and 76.2%, respectively; assisted primary patency rates were 84.3% and 81.7%, and secondary patency remained 95.5%. Median Villalta score improved from 10.5 to 1.0 (p < 0.0001). At follow-up, 89.8% of limbs were PTS-free; 10.2% had mild PTS, with no moderate/severe cases. Median hospital stay was 1 day. No major complications or 30-day mortality occurred.</p><p><strong>Conclusion: </strong>ClotTriever MT achieved high technical success, sustained patency, and significant symptom improvement. Comparative trials are needed to confirm its efficacy versus standard anticoagulation.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francois H Cornelis, Rozan Bokhari, Ruben Geevarghese, Dimitrios K Filippiadis
{"title":"Cryoneurolysis: Parallel Growth in PubMed Publications and Google Trends Analysis Reveals Exponential Interest.","authors":"Francois H Cornelis, Rozan Bokhari, Ruben Geevarghese, Dimitrios K Filippiadis","doi":"10.1007/s00270-025-04118-3","DOIUrl":"https://doi.org/10.1007/s00270-025-04118-3","url":null,"abstract":"<p><strong>Purpose: </strong>This study analyzed global interest in cryoneurolysis, a minimally invasive nerve ablation technique for non-opioid pain management, identifying temporal trends, geographic distribution, and commercial drivers influencing adoption.</p><p><strong>Materials and methods: </strong>Retrospective analysis of Google Trends data (January 2004-March 2025) and PubMed publications (1993-2025) using the keyword \"cryoneurolysis.\" Statistical analyses included Mann-Kendall trend tests, Portmanteau white noise tests, Dickey-Fuller unit root tests, and Spearman correlations. Forecasting employed nonseasonal Holt-Winters smoothing and local polynomial regression.</p><p><strong>Results: </strong>Search interest remained negligible (SVI = 0) from 2004 to mid-2019, with academic activity preceding public interest by 3-4 years. Both datasets demonstrated significant upward trends (PubMed: τ = 0.80, p < 0.0001; Google Trends: τ = 0.75, p < 0.0001). Commercial driver \"Iovera\" showed perfect correlation (r = 1.0) with search volume. Geographic concentration was limited to six high-income countries. Forecasting projects sustained growth through 2030, with publications increasing from 46.1 (95% CI: 41.8-50.4) in 2025 to 72.6 (95% CI: 59.2-86.0) by 2030.</p><p><strong>Conclusion: </strong>Analysis reveals parallel academic-public interest growth driven by commercial factors, geographic concentration in developed nations, and emerging applications in interventional radiology, suggesting wider adoption by 2030.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vanesa Lucas-Cava, Francisco Miguel Sánchez-Margallo, Fei Sun
{"title":"Effectiveness and Safety of Prostatic Artery Embolization for Patients with Prostate Cancer: A Systematic Review and Meta-Analysis.","authors":"Vanesa Lucas-Cava, Francisco Miguel Sánchez-Margallo, Fei Sun","doi":"10.1007/s00270-025-04107-6","DOIUrl":"https://doi.org/10.1007/s00270-025-04107-6","url":null,"abstract":"<p><strong>Purpose: </strong>Prostatic artery embolization (PAE) has received attention to manage the urological symptoms in patients with prostate cancer (PCa). This meta-analysis evaluates its effectiveness and safety in patients with PCa.</p><p><strong>Material and methods: </strong>A systematic review was performed by searching in PudMed and Web of Science databases for studies including either PAE or prostatic artery chemoembolization (PACE) in patients with PCa. Quantitative and qualitative analyses were performed. The primary outcomes were technical success, clinical success, oncological efficacy and adverse events (AEs). The secondary outcomes were International Prostate Symptoms Score (IPSS), quality of life (QoL), prostate volume (PV), and prostate-specific antigen (PSA).</p><p><strong>Results: </strong>Eleven single-arm studies with 151 participants were included. The pooled technical and clinical success rates were 95.53% (95%CI: 87.23, 99.95) and 90.31% (95%CI: 73.44, 99.85), respectively, whereas the oncological efficacy was 65.89% (95%CI: 32.18, 93.13). AEs showed low rates of minor 23.88% (95%CI: 8.88, 42.39) and major 0.6% (95%CI: 0.00, 3.67). Although, PAE tended to fewer AEs compared to PACE, 20.76% vs 31.03% for minor, and 1.01% vs 0.32% for major AEs, respectively. In addition, there was a statistically significant reduction in IPSS (- 10.24, 95%CI: - 14.60,- 5.89), QoL (- 2.28, 95%CI: - 3.25, - 1.32), PV (- 22.16, 95%CI: - 34.20, - 10.13), and PSA (- 7.32, 95%CI: - 12.34, - 2.29), with greater improvements after PACE. Overall, the studies showed a high risk of bias.</p><p><strong>Conclusion: </strong>This meta-analysis revealed that PAE and PACE are feasible, effective, and safe techniques to control the urological symptoms in patients with PCa, and even as adyuvant treatment for local therapies.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":""},"PeriodicalIF":2.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laetitia Saccenti, Nicole Varble, Tabea Borde, Hannah Huth, Michael Kassin, Ifechi Ukeh, Ivan Bakhutashvili, Ashley Golbus, Lindsey Hazen, Sheng Xu, Vania Tacher, Hicham Kobeiter, Keith Horton, Ming Li, Bradford Wood
{"title":"Integrated Needle Guide on Smartphone for Percutaneous Interventions Using Augmented Reality.","authors":"Laetitia Saccenti, Nicole Varble, Tabea Borde, Hannah Huth, Michael Kassin, Ifechi Ukeh, Ivan Bakhutashvili, Ashley Golbus, Lindsey Hazen, Sheng Xu, Vania Tacher, Hicham Kobeiter, Keith Horton, Ming Li, Bradford Wood","doi":"10.1007/s00270-025-04044-4","DOIUrl":"10.1007/s00270-025-04044-4","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to describe the workflow and evaluate the accuracy of a novel smartphone augmented reality (AR) application that includes an integrated needle guide, in a phantom.</p><p><strong>Materials and methods: </strong>A smartphone cover with an integrated needle guide was designed and 3D-printed. An AR application for percutaneous application was developed, which integrated a projected needle path based on the rigid needle guide. After planning the needle path using this novel tool, the operator could place the needle through the guide to reach the target. Six lesions with out-of-plane entry points were targeted on an abdominal phantom. Timing and accuracy of needle placements were measured on post-procedural CT both using smartphone AR guidance and with a freehand approach. Results were compared using Wilcoxon rank sum and Pearson's chi-squared tests.</p><p><strong>Results: </strong>A total of 108 needle placements were performed by 9 physicians with widely varying experience. The median accuracy was 4 mm (IQR 3-6 mm) using the smartphone versus 18 mm (IQR 9-27 mm) for freehand (P < 0.001). Using the smartphone AR application, planning time was 91 s (IQR 71-151 s), and puncture time was 68 s (IQR 57-77 s). There was no difference in accuracy, planning, or puncture times according to experience level when using the AR tool.</p><p><strong>Conclusion: </strong>This smartphone application with an integrated needle guide allows path planning and accurate needle placement on phantoms with real-time angular feedback in less than 3 min. This technology could promote standardization, reduce experience requirements, or provide accurate low-cost guidance in environments without procedural imaging for percutaneous interventions.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"1042-1052"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143954711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Radiation-Free Cannulation of the Uterine Artery during Fibroid Embolization Using Fiberoptic Real Shape Technology.","authors":"Timo A Auer, Federico Collettini","doi":"10.1007/s00270-025-04054-2","DOIUrl":"10.1007/s00270-025-04054-2","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"1063-1065"},"PeriodicalIF":2.8,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12267370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144109925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}