CardioVascular and Interventional Radiology最新文献

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Percutaneous Image-Guided Cryoablation of Endometriosis Scars in Unusual Anatomic Locations. 特殊解剖部位子宫内膜异位症疤痕的经皮图像引导冷冻消融。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-19 DOI: 10.1007/s00270-025-04017-7
Roberto Luigi Cazzato, Behnam Shaygi, Lorenzo Bertolotti, Julia Weiss, Aline Host, Emilie Faller, Afshin Gangi
{"title":"Percutaneous Image-Guided Cryoablation of Endometriosis Scars in Unusual Anatomic Locations.","authors":"Roberto Luigi Cazzato, Behnam Shaygi, Lorenzo Bertolotti, Julia Weiss, Aline Host, Emilie Faller, Afshin Gangi","doi":"10.1007/s00270-025-04017-7","DOIUrl":"10.1007/s00270-025-04017-7","url":null,"abstract":"<p><strong>Purpose: </strong>To report the pain relief and procedure-related outcomes of percutaneous cryoablation (CA) of painful endometriosis deposits in unusual anatomic locations.</p><p><strong>Materials and methods: </strong>A retrospective search of institutional radiological information system identified a total of 15 patients (median age 35.5 years; interquartile ranges-IQR 33-38). Patients and lesions specific data as well as procedural and follow-up information were collected, analyzed, and presented using descriptive statistical methods.</p><p><strong>Results: </strong>A total of 16 painful target lesions situated in the umbilicus (7/16; 43.8%), diaphragm (4/16; 25.0%), inguinal canal (3/16; 18.8%), and within the muscular layers of the uterus (i.e., adenomyosis; 2/16; 12.4%) underwent CA. The median of the largest diameter of the target lesions was 19 mm (IQR 13-22.3). Primary and secondary rates of complete pain relief were achieved in 86.7% (13/15 patients) and 93.3% (14/15 patients; one patient receiving additional CA for recurring pain) of patients, respectively. Each lesion underwent one single intervention, thus accounting for a total of 16 CA procedures. Eleven interventions were carried out under general anesthesia (11/16; 68.8%), with combination of ultrasound and cross-sectional imaging (CT or MRI) being the most used modality for image guidance (10/16; 62.5%). Nearly all interventions (15/16; 93.8%) required adjunctive protective measures with hydrodissection (13/16; 81.3%) and combination of hydrodissection and cutaneous protection with warm saline filled gloves (9/16; 56.3%) being the two most common protective measures. Two (2/16; 12.5%) complications were noted.</p><p><strong>Conclusions: </strong>Percutaneous CA of painful endometriosis deposits in unusual anatomic locations seems highly effective and safe.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"543-550"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to: Inferior and Superior Vena Cava Reconstruction. 矫正:下腔静脉和上腔静脉重建。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 DOI: 10.1007/s00270-025-03989-w
Rick de Graaf, Arne Estler, Gerd Grözinger
{"title":"Correction to: Inferior and Superior Vena Cava Reconstruction.","authors":"Rick de Graaf, Arne Estler, Gerd Grözinger","doi":"10.1007/s00270-025-03989-w","DOIUrl":"10.1007/s00270-025-03989-w","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"582"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11958361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143603999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Portal vein Recanalization via Paraumbilical vein with Direct Intrahepatic Portosystemic Shunt (PVR-DIPS) in Chronic Budd-Chiari Syndrome with Extrahepatic Portal Venous Obstruction. 经脐旁静脉直接肝内门静脉系统分流(PVR-DIPS)治疗慢性布-恰利综合征肝外门静脉阻塞的研究。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-04 DOI: 10.1007/s00270-025-03999-8
Saurabh Kumar, Apoorva Batra, Rinkesh Kumar Bansal, Zubin Dev Sharma, Shubham Sisodia
{"title":"Portal vein Recanalization via Paraumbilical vein with Direct Intrahepatic Portosystemic Shunt (PVR-DIPS) in Chronic Budd-Chiari Syndrome with Extrahepatic Portal Venous Obstruction.","authors":"Saurabh Kumar, Apoorva Batra, Rinkesh Kumar Bansal, Zubin Dev Sharma, Shubham Sisodia","doi":"10.1007/s00270-025-03999-8","DOIUrl":"10.1007/s00270-025-03999-8","url":null,"abstract":"<p><p>Direct intrahepatic portosystemic shunt (DIPS) with access to the portal vein from the IVC remains a viable option to ameliorate features of portal hypertension in patients of BCS with chronically thrombosed hepatic veins. We present a case of BCS with concurrent extrahepatic portal vein obstruction (EHPVO), in which portal vein recanalization (PVR) was achieved utilizing recanalized paraumbilical venous access. Subsequently PVR-DIPS was performed to ameliorate features of portal hypertension.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"447-449"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555947","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Less Aortic Neck Dilatation of the ALTO Stent Graft compared to the Self-Expanding Stent Grafts after Endovascular Aortic Repair for Abdominal Aortic Aneurysms. 腹主动脉瘤血管内修复后,与自体扩张支架相比,ALTO支架的主动脉颈部扩张较小。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-17 DOI: 10.1007/s00270-025-03996-x
Shigeo Ichihashi, Mitsuyoshi Takahara, Naoki Fujimura, Terutoshi Yamaoka, Hiroshi Banno, Masami Shingaki, Kazuo Shimamura, Fumiaki Kimura, Yoshihiko Kurimoto, Ken Nakazawa, Kiyomitsu Yasuhara, Naoki Toya, Yutaka Kobayashi, Yoshiaki Saito, Tsuyoshi Shibata, Kenjiro Kaneko, Shinsuke Kotani, Yamato Tamura, Seiji Onitsuka, Francesco Bolstad, Shinichi Iwakoshi, Shoji Sakaguchi, Toshihiro Tanaka, Kimihiko Kichikawa
{"title":"Less Aortic Neck Dilatation of the ALTO Stent Graft compared to the Self-Expanding Stent Grafts after Endovascular Aortic Repair for Abdominal Aortic Aneurysms.","authors":"Shigeo Ichihashi, Mitsuyoshi Takahara, Naoki Fujimura, Terutoshi Yamaoka, Hiroshi Banno, Masami Shingaki, Kazuo Shimamura, Fumiaki Kimura, Yoshihiko Kurimoto, Ken Nakazawa, Kiyomitsu Yasuhara, Naoki Toya, Yutaka Kobayashi, Yoshiaki Saito, Tsuyoshi Shibata, Kenjiro Kaneko, Shinsuke Kotani, Yamato Tamura, Seiji Onitsuka, Francesco Bolstad, Shinichi Iwakoshi, Shoji Sakaguchi, Toshihiro Tanaka, Kimihiko Kichikawa","doi":"10.1007/s00270-025-03996-x","DOIUrl":"10.1007/s00270-025-03996-x","url":null,"abstract":"<p><strong>Purpose: </strong>Proximal neck dilatation (PND) is a common issue after endovascular aneurysm repair (EVAR) for abdominal aortic aneurysms (AAAs), being a potential cause of stent graft migration or type Ia endoleak. The ALTO stent graft, featuring a unique polymer sealing mechanism, has been reported to exhibit less PND. This study aims to compare PND and clinical outcomes between the ALTO stent graft and alternative self-expanding stent grafts.</p><p><strong>Methods: </strong>The CustomSEAL study is a multi-center retrospective observational study involving 18 institutions in Japan. It compares EVAR outcomes using the ALTO stent graft and alternative self-expanding stent grafts for fusiform AAAs. The primary outcome measure was the difference in PND at 12 months post-EVAR. Secondary outcome measures included aneurysm sac diameter changes, reintervention rates, and mortality outcomes during the follow-up.</p><p><strong>Results: </strong>After propensity score matching, 111 patient pairs were extracted. Baseline characteristics, including proximal neck length/diameter and stent graft oversizing, were comparable between groups. The ALTO stent graft was associated with significantly less PND at 12 months (2.3% vs. 26.7%, P < 0.001). There were no significant differences in perioperative outcomes, aneurysm sac diameter changes, reintervention rates, or overall survival between the groups.</p><p><strong>Conclusions: </strong>The ALTO stent graft demonstrated significantly less PND at 12 months post-EVAR compared to alternative self-expanding stent grafts, highlighting its potential advantage in exerting less chronic expanding force on the proximal aortic neck. Long-term follow-up is needed to validate the clinical benefits of the ALTO stent graft over the alternative self-expanding stent grafts.</p><p><strong>Level of evidence: </strong>Non-randomized controlled cohort/follow-up study.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"438-446"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multicenter, PrOspective, Randomized, Controlled Trial Comparing GenIcular Artery EmbOlization Using Embosphere Microspheres to Corticosteroid iNjections for the Treatment of Symptomatic Knee Osteoarthritis: MOTION Study Protocol Summary. 多中心、前瞻性、随机、对照试验比较用栓塞微球和皮质类固醇注射栓塞治疗症状性膝骨关节炎:运动研究方案总结。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-06 DOI: 10.1007/s00270-025-03994-z
Clare Bent, Craig J McAsey, Sandeep Bagla
{"title":"Multicenter, PrOspective, Randomized, Controlled Trial Comparing GenIcular Artery EmbOlization Using Embosphere Microspheres to Corticosteroid iNjections for the Treatment of Symptomatic Knee Osteoarthritis: MOTION Study Protocol Summary.","authors":"Clare Bent, Craig J McAsey, Sandeep Bagla","doi":"10.1007/s00270-025-03994-z","DOIUrl":"10.1007/s00270-025-03994-z","url":null,"abstract":"<p><strong>Purpose: </strong>Corticosteroid injections are commonly used to treat symptomatic knee osteoarthritis; however, pain relief is usually transient. Genicular artery embolization (GAE) has shown promise as an effective minimally invasive intervention to alleviate symptomatic knee osteoarthritis. The MOTION study is being conducted to compare outcomes following GAE versus corticosteroid injection.</p><p><strong>Materials and methods: </strong>This is an international, multicenter, randomized controlled investigational device exemption (IDE) study enrolling adults (≥ 21 years old) with symptomatic knee osteoarthritis (Kellgren-Lawrence grades 1-4) across ≥ 45 centers worldwide. Patients will be randomized 1:1 to receive GAE with Embosphere® Microspheres (Merit Medical Systems, Inc.) or corticosteroid injections. The primary efficacy measure is clinical success at 6 months, defined as ≥ 50% improvement in the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) Pain Subscale. The primary safety measure is the proportion of patients free from treatment-related safety event(s) through 6-month post-index procedure (GAE or corticosteroid injection). Following the 6-month visit, patients in either cohort who do not achieve clinical success may crossover to the other study arm. Additional study measures will assess safety and efficacy outcomes throughout the 24-month follow-up period. The target sample size is 264 (132 per arm) and is based on the number of patients needed to confirm superior efficacy of GAE versus corticosteroid injections and non-inferiority with respect to safety. The overall study power is > 80%.</p><p><strong>Discussion: </strong>Findings from the MOTION study are expected to provide information on the magnitude of the therapeutic benefits associated with GAE versus standard of care over 24 months.</p><p><strong>Trial registration: </strong>NCT05818150.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"551-558"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11958495/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143572141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Case series of Breast Desmoid Tumours Treated by Percutaneous Cryoablation. 经皮冷冻消融治疗乳腺硬纤维瘤病例系列。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-04 DOI: 10.1007/s00270-025-04000-2
Georgia Tsoumakidou, Ana Dolcan, Ioannis Voutsadakis, Ilianna Galli-Vareia, Rafael Duran, Nicolas Villard, Antonia Digklia
{"title":"Case series of Breast Desmoid Tumours Treated by Percutaneous Cryoablation.","authors":"Georgia Tsoumakidou, Ana Dolcan, Ioannis Voutsadakis, Ilianna Galli-Vareia, Rafael Duran, Nicolas Villard, Antonia Digklia","doi":"10.1007/s00270-025-04000-2","DOIUrl":"10.1007/s00270-025-04000-2","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"570-571"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventional Radiologists Must be Involved in the Management of Patients with Massive and Sub-massive Pulmonary Embolism. 介入放射科医师必须参与对大面积和亚大面积肺栓塞患者的治疗。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-04 DOI: 10.1007/s00270-025-03992-1
Gerard O'Sullivan, Stefan Müller-Hülsbeck, Patrick Haage, Florian Wolf, Mohamad Hamady, Romaric Loffroy, Fabrizio Fanelli, Hicham Kobeiter, Robert A Morgan
{"title":"Interventional Radiologists Must be Involved in the Management of Patients with Massive and Sub-massive Pulmonary Embolism.","authors":"Gerard O'Sullivan, Stefan Müller-Hülsbeck, Patrick Haage, Florian Wolf, Mohamad Hamady, Romaric Loffroy, Fabrizio Fanelli, Hicham Kobeiter, Robert A Morgan","doi":"10.1007/s00270-025-03992-1","DOIUrl":"10.1007/s00270-025-03992-1","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"423-426"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143555904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor on "Newly Designed, Self-Expanding Large-Bore Nitinol Stents for Symptomatic Central Venous Stenosis: Technical and Long-Term Clinical Outcome". 致编辑的信“新设计的,自膨胀大口径镍钛诺支架治疗症状性中心静脉狭窄:技术和长期临床结果”。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2024-12-26 DOI: 10.1007/s00270-024-03950-3
Yi Deng, Wei Cui, Jing Li
{"title":"Letter to the Editor on \"Newly Designed, Self-Expanding Large-Bore Nitinol Stents for Symptomatic Central Venous Stenosis: Technical and Long-Term Clinical Outcome\".","authors":"Yi Deng, Wei Cui, Jing Li","doi":"10.1007/s00270-024-03950-3","DOIUrl":"10.1007/s00270-024-03950-3","url":null,"abstract":"","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"578-579"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142892296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
30-Day Outcomes of Real-World Elective Carotid Stenosis Treatment Using a Dual-Layer Micromesh Stent (ROADSAVER Study). 使用双层微孔支架治疗选择性颈动脉狭窄的30天结果(ROADSAVER研究)。
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-03-19 DOI: 10.1007/s00270-025-04003-z
Ralf Langhoff, Zsolt Vajda, Piotr Odrowąż-Pieniążek, Aleksandar Gjoreski, Roel Beelen, Koen Deloose, Balázs Nemes, Zoltán Ruzsa, Jean-Luc Banos, Sérgio Castro, Benjamin Faurie, Torsten Fuß, Michael Piorkowski, Istvan Király, Ivan Vulev, Arne Schwindt, Péter Csécsei, Alejandro Tomasello Weitz, Tomáš Jonszta, Paweł Latacz, Jorge Galván Fernández, Jürgen Verbist, Henrik Schröder, Christiane Pöckler-Schöniger, Karlis Kupcs, Pascual Lozano Vilardell, Rubén Rodríguez Carvajal, Kim Daenens, Matthias Tenholt, Peter Blaško, Olivier François, José Luis Diaz Valiño, Francisco Javier Martínez Gámez, Volker Sesselmann, Pál Bárzo, Wiebke Kurre, Mikel Terceño Izaga, Antonio Orgaz Pérez-Grueso, Karol Suppan, Jiří Lacman, José Angel Larrea Peña, Jordi Blasco, Reinoud Bokkers, Vladimir Cvetić, Viktor Till, Heliodoro Vallés González, Martin Andrassy, Daniel van den Heuvel, Jürgen Köhler, Stefan Müller-Hülsbeck, Sasko Kedev
{"title":"30-Day Outcomes of Real-World Elective Carotid Stenosis Treatment Using a Dual-Layer Micromesh Stent (ROADSAVER Study).","authors":"Ralf Langhoff, Zsolt Vajda, Piotr Odrowąż-Pieniążek, Aleksandar Gjoreski, Roel Beelen, Koen Deloose, Balázs Nemes, Zoltán Ruzsa, Jean-Luc Banos, Sérgio Castro, Benjamin Faurie, Torsten Fuß, Michael Piorkowski, Istvan Király, Ivan Vulev, Arne Schwindt, Péter Csécsei, Alejandro Tomasello Weitz, Tomáš Jonszta, Paweł Latacz, Jorge Galván Fernández, Jürgen Verbist, Henrik Schröder, Christiane Pöckler-Schöniger, Karlis Kupcs, Pascual Lozano Vilardell, Rubén Rodríguez Carvajal, Kim Daenens, Matthias Tenholt, Peter Blaško, Olivier François, José Luis Diaz Valiño, Francisco Javier Martínez Gámez, Volker Sesselmann, Pál Bárzo, Wiebke Kurre, Mikel Terceño Izaga, Antonio Orgaz Pérez-Grueso, Karol Suppan, Jiří Lacman, José Angel Larrea Peña, Jordi Blasco, Reinoud Bokkers, Vladimir Cvetić, Viktor Till, Heliodoro Vallés González, Martin Andrassy, Daniel van den Heuvel, Jürgen Köhler, Stefan Müller-Hülsbeck, Sasko Kedev","doi":"10.1007/s00270-025-04003-z","DOIUrl":"10.1007/s00270-025-04003-z","url":null,"abstract":"<p><strong>Purpose: </strong>Carotid artery stenting with single-layer stents carries a risk of periprocedural cerebral embolization compared to carotid endarterectomy. Dual-layer micromesh stents were designed for improved plaque coverage and sustained embolic protection. This analysis aimed to confirm the Roadsaver dual-layer micromesh stent safety in a real-world carotid artery stenting cohort.</p><p><strong>Materials and methods: </strong>ROADSAVER was a prospective, single-arm, multicenter, observational study. Patients with carotid artery stenosis, eligible for elective stenting, were enrolled at 52 sites across 13 European countries. All procedures followed standard practice. The primary outcome was the 30-day major adverse event rate, defined as the cumulative incidence of any death or stroke. All deaths, strokes, and carotid artery revascularizations were independently adjudicated.</p><p><strong>Results: </strong>In total, 1965 patients were analysed (mean age 70.6 ± 8.8 years). Cerebral ischaemia symptoms were present in 49.4% of participants. Radial/ulnar access was used in 26.3% of cases and embolic protection in 63.8%. The 30-day major adverse event incidence was 2.2% (1.6% in asymptomatic and 2.8% in symptomatic patients), with any stroke at 1.9%, any death at 0.8%, and stroke-related death at 0.5%. Predictors of higher 30-day major adverse event risk, identified through multivariable modelling, included residual stenosis ≥ 30%, thromboembolic venous disease, previous myocardial infarction, age ≥ 75 years, family history of atherosclerosis, non-insulin-dependent diabetes mellitus, symptomatic carotid stenosis, and stent length.</p><p><strong>Conclusion: </strong>Dual-layer micromesh carotid artery stenting is safe, with a low 30-day major adverse event incidence in real-world asymptomatic and symptomatic patients, supporting the sustained embolic protection design concept.</p><p><strong>Level of evidence: </strong>Level 2, observational study (with dramatic effect).</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"427-437"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11958397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143662577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Six-Month Outcomes from the Prospective, Multi-Center, Non-Randomized Clinical Study of the COVERA() Arterio VeNous (AV) Stent Graft in the Treatment of Stenosis in the VEnous OutfloW of AV Fistula Access Circuits (AVeNEW PAS). COVERA(™)动静脉(AV)支架治疗房内瘘通路(AVeNEW PAS)静脉流出狭窄的六个月前瞻性、多中心、非随机临床研究结果
IF 2.8 3区 医学
CardioVascular and Interventional Radiology Pub Date : 2025-04-01 Epub Date: 2025-01-09 DOI: 10.1007/s00270-024-03930-7
Bart Dolmatch, Talar Saber, Margo Underwood
{"title":"Six-Month Outcomes from the Prospective, Multi-Center, Non-Randomized Clinical Study of the COVERA<sup>(</sup>™<sup>)</sup> Arterio VeNous (AV) Stent Graft in the Treatment of Stenosis in the VEnous OutfloW of AV Fistula Access Circuits (AVeNEW PAS).","authors":"Bart Dolmatch, Talar Saber, Margo Underwood","doi":"10.1007/s00270-024-03930-7","DOIUrl":"10.1007/s00270-024-03930-7","url":null,"abstract":"<p><strong>Purpose: </strong>The AVeNEW Post-Approval Study (AVeNEW PAS) follows upon results from the AVeNEW IDE clinical trial and was designed to provide additional clinical evidence of safety and effectiveness using the Covera™ Vascular Covered Stent to treat arteriovenous fistula (AVF) stenoses in a real-world hemodialysis patient population.</p><p><strong>Materials and methods: </strong>One hundred AVF patients were prospectively enrolled at 11 clinical trial sites in the USA and treated with the covered stent after angioplasty of a clinically significant target stenosis. The primary safety outcome was freedom from any adverse event that suggests the involvement of the AV access circuit evaluated at 30 days. The primary efficacy outcome was Target Lesion Primary Patency (TLPP) at six months, determined by an independent core laboratory. Secondary outcome measures included technical success defined as successful deployment to the intended location and access circuit primary patency (ACPP).</p><p><strong>Results: </strong>Safety was 94.9% with no device-related deaths nor in-patient hospitalization. Technical success was 100%. TLPP rates at 1, 3, and 6 months were 100, 89.7, and 82.2%. ACPP rates at 1, 3, and 6 months were 98, 76.3, and 60.0%. Target stenoses were 81% restenotic, and 75% located in the cephalic vein arch. There were 35% non-target stenoses treated with angioplasty during the index procedure.</p><p><strong>Conclusion: </strong>The 6-month results of the AVeNEW PAS confirm results from the AVeNEW IDE clinical trial and demonstrate safety and efficacy using the Covera<sup>(</sup>™<sup>)</sup> Covered Stent in a real-world US hemodialysis patient population.</p><p><strong>Trial registration: </strong>NCT04261686.</p><p><strong>Level of evidence: </strong>3 - prospective, multicenter.</p>","PeriodicalId":9591,"journal":{"name":"CardioVascular and Interventional Radiology","volume":" ","pages":"460-471"},"PeriodicalIF":2.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11958458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142944960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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