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Breast Cancer Prevention with a Plant-Based Diet 以植物性饮食预防乳腺癌
Cancer Therapy & Oncology International Journal Pub Date : 2020-10-22 DOI: 10.19080/ctoij.2020.17.555955
A. Strombom
{"title":"Breast Cancer Prevention with a Plant-Based Diet","authors":"A. Strombom","doi":"10.19080/ctoij.2020.17.555955","DOIUrl":"https://doi.org/10.19080/ctoij.2020.17.555955","url":null,"abstract":"Diet may be an independent risk factor for breast cancer, along with alcohol, physical activity, BMI and smoking. Several epidemiological studies show a decreased risk of breast cancer for vegetarians and vegans. Studies show an increased risk in women exposed to heterocyclic amines (HCAs), polyaromatic hydrocarbons (PAHs) and persistent organic pollutants (POPs). POPs resist environmental degradation and accumulate in animal adipose tissue, while PAHs and HCAs are produced during cooking of meat. In addition to reducing their exposure to these carcinogenic compounds, those following a plant-based diet benefit from the increased consumption of phytochemicals and fiber found in plant foods. In particular, studies show that soy may reduce the risk of breast cancer and breast cancer recurrence, due to its isoflavone content. Dietary fiber also reduces the risk of breast cancer, most likely by affecting estrogen levels. Most breast cancer patients tend to be older. The plant-based diet can reduce the risk of common comorbidities in post-menopausal women such as type II diabetes, coronary artery disease, arthritis, hypertension and thyroid disease. The plant-based diet is safe and has no adverse reactions or contraindications. It presents a valuable additional therapeutic measure to chemotherapy, radiation and surgery which will continue as standard of care.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80759011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
A Rare Case of Cervix Metastasis from a Breast Primary 一例罕见的乳房原发宫颈转移
Cancer Therapy & Oncology International Journal Pub Date : 2020-10-13 DOI: 10.19080/ctoij.2020.17.555954
S. Goel
{"title":"A Rare Case of Cervix Metastasis from a Breast Primary","authors":"S. Goel","doi":"10.19080/ctoij.2020.17.555954","DOIUrl":"https://doi.org/10.19080/ctoij.2020.17.555954","url":null,"abstract":"The patients presenting with metastasis to cervix are handful. Breast is one of the common extragenital site that can metastasize to cervix. Early diagnosis and treatment are the keys to right management. We hereby report an advanced case of breast cancer that was found to have an incidental synchronous lesion in cervix on a PET Scan. She showed limited response to systemic treatment. The overall survival was 8.5 months. metastasize to unusual sites. Infiltrating ductal carcinoma metastasizing to cervix is rare and few cases have been reported till now. A thorough gynecological examination is often recommended. Immunohistochemistry can differentiate between a primary and metastatic cervical lesion and should be done wherever feasible.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80389990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Coronavirus Disease - 2019 (Covid-19) Pandemic and Cancer - A Cochrane Review 冠状病毒病- 2019 (Covid-19)大流行与癌症- Cochrane综述
Cancer Therapy & Oncology International Journal Pub Date : 2020-10-08 DOI: 10.19080/ctoij.2020.17.555953
Dr P K Prem Ravi Varma
{"title":"Coronavirus Disease - 2019 (Covid-19) Pandemic and Cancer - A Cochrane Review","authors":"Dr P K Prem Ravi Varma","doi":"10.19080/ctoij.2020.17.555953","DOIUrl":"https://doi.org/10.19080/ctoij.2020.17.555953","url":null,"abstract":"mortality Abstract Purpose: Whether cancer is associated with worse prognosis among patients with COVID-19 is unknown. I aimed to quantify the effect (if any) of the presence as opposed to absence of cancer on important clinical outcomes of patients with COVID-19 by carrying out a literature review in Cochrane Library. Methods: I systematically searched Cochrane Library database, medRxiv, COVID-19 Open Research Dataset (CORD-19), and references of relevant articles up to April 27, 2020, to identify observational studies comparing patients with versus without cancer infected with COVID-19 and to report on mortality and/or need for admission to the intensive care unit (ICU). Results: A total of 32 studies involving 46,499 patients (1,776 patients with cancer) with COVID-19 from Asia, Europe, and the United States were included. All-cause mortality was higher in patients with versus those without cancer (2,034 deaths; 8 studies with 37,807 patients). The need for ICU admission was also more likely in patients with versus without cancer (3,220 events; 26 studies with 15,375 patients). However, in a prespecified subgroup analysis of patients > 65 years of age, all-cause mortality was comparable between those with versus without cancer (915 deaths; RR, 1.06; 95% CI, 0.79 to 1.41; P = .71; 8 studies with 5,438 patients). Conclusion: associated with worse clinical outcomes among patients with COVID-19. However, elderly patients with cancer may not be at increased risk of death when infected with COVID-19. These findings may inform discussions of clinicians with patients about prognosis and may guide health policies.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88023221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MELANOMA -Diagnosis, Pathology and Molecular Biology 黑色素瘤的诊断、病理和分子生物学
Cancer Therapy & Oncology International Journal Pub Date : 2020-09-28 DOI: 10.19080/CTOIJ.2020.17.555952
A. Hunis
{"title":"MELANOMA -Diagnosis, Pathology and Molecular Biology","authors":"A. Hunis","doi":"10.19080/CTOIJ.2020.17.555952","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.17.555952","url":null,"abstract":"Melanoma is one of the tumors where diagnosis, monitoring and treatment have been most developed with determinations that include the use of molecular biology. New drugs, new combinations of drugs today result in answers that were unthinkable only five years ago. More patients live longer and many of them with advanced disease achieve survival measured in years when years ago we measured it in weeks. In this review we will see the main articles that were presented at ASCO 2020 and what they have left us, to put them into practice for the benefit of our patients.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"87 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91455445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Myelodysplastic Syndrome and Colon Cancer Relationship: A Case Report 骨髓增生异常综合征与结肠癌的关系1例报告
Cancer Therapy & Oncology International Journal Pub Date : 2020-09-15 DOI: 10.19080/CTOIJ.2020.17.555951
Asmaa El Hussainy
{"title":"Myelodysplastic Syndrome and Colon Cancer Relationship: A Case Report","authors":"Asmaa El Hussainy","doi":"10.19080/CTOIJ.2020.17.555951","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.17.555951","url":null,"abstract":"The use of alkylating agent and antimetabolite is associated with the development of therapy related acute leukemia or myelodysplastic syndrome. MDS may also occur as a separate entity in Patients of CRC who are treated with chemotherapy. The average time until onset of tMDS depends on the type and amount of chemotherapy used and varies from 2 to 7 years. We are presenting a case that had MDS shortly after treatment of CRC with Adjuvant Chemotherapy which is not a common entity. : A 66 years old man was diagnosed as a case of colon cancer treated by surgery followed by chemotherapy for 6 months. Myelodysplastic syndrome was diagnosed due to persistent anemia post chemotherapy. He is under follow up with GIT unit for colon cancer and hematology unit for treatment of myelodysplastic syndrome. between colon cancer chemotherapy treatment and myelodysplastic syndrome.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"99 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76983307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Update in Management Strategies of Chronic Myeloid Leukemia 慢性髓系白血病治疗策略的最新进展
Cancer Therapy & Oncology International Journal Pub Date : 2020-09-03 DOI: 10.19080/CTOIJ.2020.16.555949
N. Hamed
{"title":"Update in Management Strategies of Chronic Myeloid Leukemia","authors":"N. Hamed","doi":"10.19080/CTOIJ.2020.16.555949","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.16.555949","url":null,"abstract":"The goal of CML treatment in the recent era is to discontinue medication for treatment free remission after achieving a stable deep molecular response. A prerequisite for TKI discontinuation is the assessment of the remaining tumor load by standardized molecular monitoring using high quality quantitative PCR by the international scale. Molecular monitoring post-treatment suspension is also imperative for CML patients attempting TFR.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"174 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76921664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Nonage Concretion-Calcifying Aponeurotic Fibroma 老年结块钙化型腱膜纤维瘤
Cancer Therapy & Oncology International Journal Pub Date : 2020-08-28 DOI: 10.19080/CTOIJ.2020.16.555948
Anu Bajaj
{"title":"The Nonage Concretion-Calcifying Aponeurotic Fibroma","authors":"Anu Bajaj","doi":"10.19080/CTOIJ.2020.16.555948","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.16.555948","url":null,"abstract":"Calcifying aponeurotic fibroma is an exceptional, locally aggressive, benign, fibroblastic, soft tissue neoplasm commonly emerging within palms and soles of young children or adolescents. Calcifying aponeurotic fibroma was denominated as “juvenile aponeurotic fibroma” by Keasbey in 1953 [1]. As the condition incriminates a broad age group, the term “calcifying aponeurotic fibroma” is suggested and preferred. The neoplasm can be contemplated as a cartilaginous analogue of soft tissue fibromatosis. Palisading pattern of fibroblastic dissemination encompass chondroid or calcific foci. The tumour demonstrates a propensity for localized tumour reoccurrence whereas distant metastasis is absent. Calcifying aponeurotic fibroma delineates an aggressive, locally invasive, biological behaviour with an enhanced localized tumour reoccurrence following surgical resection [2]. Clinical and radiographic appearance of calcifying aponeurotic fibroma is variable and contingent to proportionate calcification and soft tissue involvement. The neoplasm is appropriately discerned by cogent histological evaluation [2].","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"34 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80847016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Use of 18f-Fdg in Oncology and its Applications in Neuroblastomas 18f-Fdg在肿瘤中的应用及其在神经母细胞瘤中的应用
Cancer Therapy & Oncology International Journal Pub Date : 2020-08-12 DOI: 10.19080/CTOIJ.2020.16.555946
Emerson Barbosa da Silva
{"title":"The Use of 18f-Fdg in Oncology and its Applications in Neuroblastomas","authors":"Emerson Barbosa da Silva","doi":"10.19080/CTOIJ.2020.16.555946","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.16.555946","url":null,"abstract":"Neuroblastoma is the most common cancer in babies and the third most common cancer in children, behind only leukemia and brain tumor. Knowing this, oncology has been working hard with research and equipment to bring the best possible treatment and diagnosis as quickly as possible to combat not only neuroblastoma but also all cancers that the individual may contract. When we speak of neuroblastoma, cancer that originates from cells of the nervous system, but we do not necessarily find the same in the nervous system since the embryonic process, the majority of which develop in the adrenal gland, so most tumors are found in the region of the abdomen, it can manifest itself in cells near the spinal cord, it can also develop in toxin.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76785214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Basocellular Skin Cancer about Three Patients Treated with Vismodegib Review of your Action Mechanism 维莫德吉治疗3例Basocellular皮肤癌患者的作用机制综述
Cancer Therapy & Oncology International Journal Pub Date : 2020-08-07 DOI: 10.19080/CTOIJ.2020.16.555945
A. Hunis
{"title":"Basocellular Skin Cancer about Three Patients Treated with Vismodegib Review of your Action Mechanism","authors":"A. Hunis","doi":"10.19080/CTOIJ.2020.16.555945","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.16.555945","url":null,"abstract":"Vismodegib (Erivedge®) is a hedgehog pathway inhibitor and is approved to treat locally advanced or metastatic basal cell carcinoma (BCC) not suitable for surgery or radiation therapy. Our main objectives were to study the intimate mechanism of action of this novel drug and to present three cases of our casuistry, the clinically evaluated objective response rate (ORR), as a contribution to the literature.","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"867 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85156791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vestibular Schwannoma’s Resection Surgical Approaches, Advantages and Disadvantages of Retrosigmoid, Middle Cranial Fossa and Translabyrinthine Surgical Approaches 前庭神经鞘瘤切除手术入路，乙状结肠后、颅中窝和迷路入路的优缺点
Cancer Therapy & Oncology International Journal Pub Date : 2020-07-31 DOI: 10.19080/CTOIJ.2020.16.555944
B. Saberi
{"title":"Vestibular Schwannoma’s Resection Surgical Approaches, Advantages and Disadvantages of Retrosigmoid, Middle Cranial Fossa and Translabyrinthine Surgical Approaches","authors":"B. Saberi","doi":"10.19080/CTOIJ.2020.16.555944","DOIUrl":"https://doi.org/10.19080/CTOIJ.2020.16.555944","url":null,"abstract":"There are various factors which would determine the selection of surgical approaches in resection of the vestibular schwannoma. Factors like experience of the surgeon, characteristics of the tumor, surgical anatomy and the patient’s condition can determine the selection of the best surgical approach for individual cases with vestibular schwannoma. There are different opinions among surgeons about the pros and cons of selecting the surgical approaches for individual patients. This is a brief review on the advantages and disadvantages of three surgical approaches in resection of the vestibular schwannoma [1-4].","PeriodicalId":9575,"journal":{"name":"Cancer Therapy & Oncology International Journal","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2020-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87702847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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