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Conceptualization of Breast Cancer and Attitudes toward Breast Cancer Screening: A Qualitative Study on Iranian and Australian Women. 乳腺癌的概念和对乳腺癌筛查的态度:伊朗和澳大利亚妇女的定性研究。
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-02-12 DOI: 10.1080/07357907.2023.2283866
Tina Parsamand, Fariba Zarani, Leili Panaghi, Cannas Kwok
{"title":"Conceptualization of Breast Cancer and Attitudes toward Breast Cancer Screening: A Qualitative Study on Iranian and Australian Women.","authors":"Tina Parsamand, Fariba Zarani, Leili Panaghi, Cannas Kwok","doi":"10.1080/07357907.2023.2283866","DOIUrl":"10.1080/07357907.2023.2283866","url":null,"abstract":"<p><strong>Objective: </strong>Regular screening can lead to early diagnosis of breast cancer. Australia is one of the countries with a high rate of participation in breast cancer screening, while in Iran, most patients are diagnosed in advanced stages. This qualitative study used a thematic analysis method to examine the attitudes and beliefs of Iranian and Australian women toward breast cancer and breast cancer screening.</p><p><strong>Method: </strong>In-depth interviews were conducted with eight Iranian and seven Australian women. Data were collected through semi-structured interviews and analyzed using thematic analysis with an inferential approach.</p><p><strong>Results: </strong>According to the results, four main themes were extracted for the perceptions of breast cancer, including \"the meaning of breast cancer\", \"causes of breast cancer\", \"prevention of breast cancer\" and \"effects of significant people in life\". Considering the perceptions of breast cancer screening, three themes were identified, including \"beliefs about breast cancer screening,\" \"sources of information about breast cancer screening,\" and \"barriers to breast cancer screening.\"</p><p><strong>Conclusion: </strong>Cultural and social factors influence women's perceptions of breast cancer and screening. Therefore, investigating the cultural meaning of breast cancer and breast cancer screening for women can be useful for screening and prevention purposes.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"34-43"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138046174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of the Multidisciplinary Cancer Team on the Diagnostic and Therapeutic Care Pathway of Early Breast Cancer Patients and Perception of Team Members: The Experience of a Cancer Centre in Italy. 多学科癌症小组对早期乳腺癌患者诊断和治疗路径的影响以及小组成员的看法：意大利一家癌症中心的经验。
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-01-22 DOI: 10.1080/07357907.2023.2300442
A M L Capobianco, G Gallucci, L Lapadula, G Dinardo, G La Torre, N Sisti, L G Sisti
{"title":"Impact of the Multidisciplinary Cancer Team on the Diagnostic and Therapeutic Care Pathway of Early Breast Cancer Patients and Perception of Team Members: The Experience of a Cancer Centre in Italy.","authors":"A M L Capobianco, G Gallucci, L Lapadula, G Dinardo, G La Torre, N Sisti, L G Sisti","doi":"10.1080/07357907.2023.2300442","DOIUrl":"10.1080/07357907.2023.2300442","url":null,"abstract":"<p><p>Literature on the role of multidisciplinary team (MDT) in cancer is still controversial. We aimed to investigate MDT impact on a panel of indicators in breast cancer care in a single-center retrospective study performed in a Cancer Reference Center in Italy. We analysed the diagnostic and therapeutic care pathway (DTCP) of 266 early breast cancer patients managed by our MDT during 2019-2020. Process indicators reflecting the change of the diagnostic and therapeutic care pathways occurred after the MDT discussion were computed. Further, the performance of some quality care indicators in breast cancer care since the establishment of the MDT activity and the breast cancer MDT members' perceptions were also investigated. According to our study, the MDT approach improves breast cancer management by increasing the completion of staging and by encouraging neo-adjuvant treatment and an appropriate and faster surgery. In MDT members' perspective it also improves decision-making and training and creates a positive work environment. Globally, our study encourages MDT rollout in breast cancer care. However, to enhance the reliability and comparability of the results of studies investigating MDT effectiveness in clinical practice, shared guidelines on its operationalisation are strongly desirable.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"12-20"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139039538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
COVID-19 Outbreak Impact on Cancer Multidisciplinary Team Meetings. A Multicenter French Experience. COVID-19 爆发对癌症多学科团队会议的影响。法国多中心经验。
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-02-05 DOI: 10.1080/07357907.2024.2311856
Wafa Bouleftour, Amandine Mondiere-Wichurski, Pierre Fournel, Quentin Reboul
{"title":"COVID-19 Outbreak Impact on Cancer Multidisciplinary Team Meetings. A Multicenter French Experience.","authors":"Wafa Bouleftour, Amandine Mondiere-Wichurski, Pierre Fournel, Quentin Reboul","doi":"10.1080/07357907.2024.2311856","DOIUrl":"10.1080/07357907.2024.2311856","url":null,"abstract":"<p><p>Multidisciplinary team meeting (MDT) became a standard of care in cancer management. The COVID-19 epidemic induced unprecedented pressure on the health system. The impact of this health crisis on MDTs held within a regional French health structures was analyzed. A decrease in the total number of records discussed in hematological, digestive, thoracic, gynecological and genitourinary MDTs was observed following the 1st wave of the COVID-19 pandemic. This decrease was generally maintained during the 2nd and 3rd wave. MDTs activity back in order from the 4th wave. The COVID-19 pandemic has challenged MDTs settings. The implementation of virtual technologies offers an opportunity to improve MDTs organization.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"4-11"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Gain of Chromosome 5q Predicts a Favorable Prognosis in Localized Renal Cell Carcinoma. 5q 染色体增益预示局部肾细胞癌的良好预后
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-02-05 DOI: 10.1080/07357907.2024.2308172
Cedric Lebacle, Aydin Pooli, Brian Shuch, Nagesh Rao, Karim Chamie, Nils Kroeger, Izak Faiena, Sandy Liu, Erika L Wood, Arie Belldegrun, Alexandra Drakaki, Allan J Pantuck
{"title":"Gain of Chromosome 5q Predicts a Favorable Prognosis in Localized Renal Cell Carcinoma.","authors":"Cedric Lebacle, Aydin Pooli, Brian Shuch, Nagesh Rao, Karim Chamie, Nils Kroeger, Izak Faiena, Sandy Liu, Erika L Wood, Arie Belldegrun, Alexandra Drakaki, Allan J Pantuck","doi":"10.1080/07357907.2024.2308172","DOIUrl":"10.1080/07357907.2024.2308172","url":null,"abstract":"<p><p>Approximately 65% of renal cell carcinomas (RCC) are diagnosed at a localized stage. We investigated the chromosome 5q gain impact on disease-free survival (DFS) in RCC patients. Overall, 676 patients with stages 1-2 RCC and having cytogenetic analysis were included. Gain of 5q was observed in 108 patients, more frequently in clear cell (ccRCC) than non-clear cell tumors. Gain of 5q is likely an independent prognostic factor since the concerned patients had a decreased recurrence risk in stages 1-2 RCC, confirmed in multivariable analysis. Detecting 5q gain could enhance recurrence risk assessment, allowing tailored post-surgery surveillance, and reducing unnecessary treatments.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"97-103"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Microvessel Density (MVD) in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis. 骨肉瘤患者的微血管密度 (MVD)：系统回顾与元分析》。
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-02-12 DOI: 10.1080/07357907.2024.2311266
Konstantinos Perivoliotis, Panagiotis Ntellas, Katerina Dadouli, Athina A Samara, Sotirios Sotiriou, Maria Ioannou, Konstantinos Tepetes
{"title":"Microvessel Density (MVD) in Patients with Osteosarcoma: A Systematic Review and Meta-Analysis.","authors":"Konstantinos Perivoliotis, Panagiotis Ntellas, Katerina Dadouli, Athina A Samara, Sotirios Sotiriou, Maria Ioannou, Konstantinos Tepetes","doi":"10.1080/07357907.2024.2311266","DOIUrl":"10.1080/07357907.2024.2311266","url":null,"abstract":"<p><p>A meta-analysis was designed and conducted to estimate the effect of tumoral microvessel density (MVD) on the survival of patients with osteosarcoma. There was no difference between high and low MVD regarding the overall (OS) and disease-free (DFS) survival. Low MVD tumors displayed a lower DFS at the third year of follow-up. Although primary metastases did not affect the mean MVD measurements, tumors with a good chemotherapy response had a higher MVD value. Although no significant differences between tumoral MVD, OS and DFS were found, good adjuvant therapy responders had a significant higher vascularization pattern.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"104-114"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139721745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Nature, Origin and Evolution of Life: Part I The Fundamental Logic and Organization of Life. 生命的本质、起源与进化：第一部分生命的基本逻辑与组织。
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2023-09-28 DOI: 10.1080/07357907.2023.2262122
Gary H Lyman, Christopher H Lyman, Nicole M Kuderer
{"title":"The Nature, Origin and Evolution of Life: Part I The Fundamental Logic and Organization of Life.","authors":"Gary H Lyman, Christopher H Lyman, Nicole M Kuderer","doi":"10.1080/07357907.2023.2262122","DOIUrl":"10.1080/07357907.2023.2262122","url":null,"abstract":"","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"1-3"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41109425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single Nucleotide Polymorphisms Associated with Prostate Cancer Progression: A Systematic Review. 与前列腺癌进展相关的单核苷酸多态性：系统综述。
IF 1.8 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2023-12-18 DOI: 10.1080/07357907.2023.2291776
Daniel Felipe Mendivelso González, Santiago Andrés Sánchez Villalobos, Andrea Estefanía Ramos, Wendy Johana Montero Ovalle, Martha Lucía Serrano López
{"title":"Single Nucleotide Polymorphisms Associated with Prostate Cancer Progression: A Systematic Review.","authors":"Daniel Felipe Mendivelso González, Santiago Andrés Sánchez Villalobos, Andrea Estefanía Ramos, Wendy Johana Montero Ovalle, Martha Lucía Serrano López","doi":"10.1080/07357907.2023.2291776","DOIUrl":"10.1080/07357907.2023.2291776","url":null,"abstract":"<p><strong>Background: </strong>New biomarkers of progression in patients with prostate cancer (PCa) are needed to improve their classification and clinical management. This systematic review investigated the relationship between single nucleotide polymorphisms (SNPs) and PCa progression.</p><p><strong>Methods: </strong>A keyword search was performed in Pubmed, EMBASE, Scopus, Web of Science, and Cochrane for publications between 2007 and 2022. We included articles with adjusted and significant associations, a median follow-up greater than or equal to 24 months, patients taken to radical prostatectomy (RP) as a first therapeutic option, and results presented based on biochemical recurrence (BCR).</p><p><strong>Results: </strong>In the 27 articles selected, 73 SNPs were identified in 39 genes, organized in seven functional groups. Of these, 50 and 23 SNPs were significantly associated with a higher and lower risk of PCa progression, respectively. Likewise, four haplotypes were found to have a significant association with PCa progression.</p><p><strong>Conclusion: </strong>This article highlights the importance of SNPs as potential markers of PCa progression and their possible functional relationship with some genes relevant to its development and progression. However, most variants were identified only in cohorts from two countries; no additional studies reproduce these findings.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"75-96"},"PeriodicalIF":1.8,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138486725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
One Heresy and One Orthodoxy: On Dialetheism, Dimathematism, and the Non-normativity of Logic. 一个异端和一个正统：论 Dialetheism、Dimathematism 和逻辑的非规范性。
IF 0.9 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2022-03-09 DOI: 10.1007/s10670-022-00528-8
Heinrich Wansing
{"title":"One Heresy and One Orthodoxy: On Dialetheism, Dimathematism, and the Non-normativity of Logic.","authors":"Heinrich Wansing","doi":"10.1007/s10670-022-00528-8","DOIUrl":"10.1007/s10670-022-00528-8","url":null,"abstract":"<p><p>In this paper, Graham Priest's understanding of dialetheism, the view that there exist true contradictions, is discussed, and various kinds of metaphysical dialetheism are distinguished between. An alternative to dialetheism is presented, namely a thesis called 'dimathematism'. It is pointed out that dimathematism enables one to escape a slippery slope argument for dialetheism that has been put forward by Priest. Moreover, dimathematism is presented as a thesis that is helpful in rejecting the claim that logic is a normative discipline.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":"1 1","pages":"181-205"},"PeriodicalIF":0.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10827935/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91313723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comorbidity in Small Cell Lung Cancer: Prognostic Impacts of Hypertension/Coronary Artery Disease, Diabetes Mellitus, and Chronic Obstructive Pulmonary Disease. 小细胞肺癌的合并症：高血压/冠状动脉疾病、糖尿病和慢性阻塞性肺病的预后影响。
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-02-01 DOI: 10.1080/07357907.2024.2310574
Faruk Tas, Akin Ozturk, Kayhan Erturk
{"title":"Comorbidity in Small Cell Lung Cancer: Prognostic Impacts of Hypertension/Coronary Artery Disease, Diabetes Mellitus, and Chronic Obstructive Pulmonary Disease.","authors":"Faruk Tas, Akin Ozturk, Kayhan Erturk","doi":"10.1080/07357907.2024.2310574","DOIUrl":"10.1080/07357907.2024.2310574","url":null,"abstract":"<p><p>Comorbidity, the most important components of which are hypertension/coronary artery disease (HTN/CAD), diabetes mellitus (DM), and chronic obstructive pulmonary disease (COPD), is frequently encountered in small cell lung cancer (SCLC) patients. We aimed to assess the possible impacts of these major comorbidities on the prognoses of SCLC patients. A total of 378 SCLC patients were analyzed retrospectively. We did not ascertain the effect of comorbidity on survival in SCLC patients in general; and similarly, the presence of HTN/CAD and COPD did not adversely affect the outcome. However, lower survival rates were observed in patients with SCLC coexisting with DM.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"21-33"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139650295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Mycobiota and Its Role in Cancer Progression, Diagnostics and Therapeutics: A Link Lesser-Known. 人类霉菌生物群及其在癌症进展、诊断和治疗中的作用：鲜为人知的联系
IF 2.4 4区 医学
Cancer Investigation Pub Date : 2024-01-01 Epub Date: 2024-01-07 DOI: 10.1080/07357907.2024.2301733
Souvik Roy, Dhrisaj Ray, Ishani Laha, Lopamudra Choudhury
{"title":"Human Mycobiota and Its Role in Cancer Progression, Diagnostics and Therapeutics: A Link Lesser-Known.","authors":"Souvik Roy, Dhrisaj Ray, Ishani Laha, Lopamudra Choudhury","doi":"10.1080/07357907.2024.2301733","DOIUrl":"10.1080/07357907.2024.2301733","url":null,"abstract":"<p><p>Although not as well studied as the bacterial component of the human microbiota, the commensal fungi or mycobiota play important roles in maintaining our health by augmenting our immune system. This mycobiota is also associated with various fatal diseases like opportunistic mycoses, and even cancer, with different cancers having respective type-specific mycobiota. The different fungal species which comprise these different intratumoral mycobiota play important roles in cancer progression. The aim of this review paper is to decipher the association between mycobiota and cancer, and shed light on new avenues in cancer diagnosis, and the development of new anti-cancer therapeutics.</p>","PeriodicalId":9463,"journal":{"name":"Cancer Investigation","volume":" ","pages":"44-62"},"PeriodicalIF":2.4,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139377224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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