Chonnam medical journalPub Date : 2024-09-01Epub Date: 2024-09-25DOI: 10.4068/cmj.2024.60.3.180
Hye-Yeon Kim, Jeong-Ho Yang, Sun-Seog Kweon
{"title":"Resilience Gap in Gastrointestinal Endoscopy Activity during the COVID-19 Pandemic in South Korea.","authors":"Hye-Yeon Kim, Jeong-Ho Yang, Sun-Seog Kweon","doi":"10.4068/cmj.2024.60.3.180","DOIUrl":"https://doi.org/10.4068/cmj.2024.60.3.180","url":null,"abstract":"<p><p>This study assessed the impact of distancing measures during the COVID-19 pandemic on cancer diagnostic activities, including gastrointestinal endoscopy (GIE). It analyzed GIE volumes from 2020 to 2022 in comparison to 2018-2019, considering variations in resilience linked to socioeconomic status (SES). The analysis utilized data from the Korean Health Insurance Review and Assessment Services database, covering the entire population and medical facilities. Diagnostic GIE rates (2018-2022) in Gwangju Metropolitan City and Jeonnam province were examined, comparing age-standardized rates (ASRs) by area, gender, and SES. The results indicated a decline in ASRs for colonoscopy and endoscopic gastroduodenoscopy (EGD) in 2020 compared to 2018-2019, followed by an increase in 2021-2022, except for EGD in the medical aid population. SES based and rural-urban disparities were evident in the recovery of GIE rates. The findings suggest that equity-focused strategies are needed to ensure equitable healthcare access among different socioeconomic groups after pandemic.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 3","pages":"180-186"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Primary Caregiver Knowledge about Self-Medication of Antibiotics in Children Aged 0-12 Years.","authors":"Shishir Kumar, Shivani Agrawal, Setu Sinha, Tajwar Yasmeen","doi":"10.4068/cmj.2024.60.3.174","DOIUrl":"https://doi.org/10.4068/cmj.2024.60.3.174","url":null,"abstract":"<p><p>Globally, it is estimated that more than 50% of antibiotics are obtained without a prescription. The main purpose of this study is to determine the knowledge and practice of primary caregivers about self-medication in children with antibiotics, as studies on self-medication is lacking in India, also, it will help is assessing parents' knowledge and attitude towards self medication. This cross-sectional study conducted in the urban community of Shastri Nagar, Patna, aimed to evaluated antibiotic use in children aged 0-12. From January 2023 to March 2023, 173 caregivers were randomly selected through house visits. Data collection used a pre-tested questionnaire, ensuring confidentiality. In this study of 173 participants, caregivers in an urban community demonstrated varying knowledge regarding antibiotic use in children. Mothers and post-graduates possessed better awareness of antibiotic consequences. Fathers exhibited better understanding of side effects. Knowledge on antibiotics' action was seen among mothers, those aged 30-39, with family income of Rs. 20,000-40,000 and those with family members in medical field. Fathers had more incorrect beliefs about antibiotics treating viral infections. Common conditions for self-medication included cough/cold, fever and diarrhea, with hospitals being the primary source of antibiotics. Majority obtained information from pharmacies but awareness about antibiotic course completion and versatility was limited. Caregivers' antibiotic knowledge varied; mothers and post-graduates were more aware, while fathers understood side effects better.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 3","pages":"174-179"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458318/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2024-09-01Epub Date: 2024-09-25DOI: 10.4068/cmj.2024.60.3.147
Sang Hoon Lee, Myung Ho Jeong, Seok Oh, Yonghwan Lim, Joon Ho Ahn, Dae Young Hyun, Seung Hun Lee, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn
{"title":"Risk of Bleeding and Ischemia in Elderly East Asian Patients with Diabetes Mellitus Treated with either Clopidogrel or Ticagrelor: From the Korean Acute Myocardial Infarction Registry-V.","authors":"Sang Hoon Lee, Myung Ho Jeong, Seok Oh, Yonghwan Lim, Joon Ho Ahn, Dae Young Hyun, Seung Hun Lee, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn","doi":"10.4068/cmj.2024.60.3.147","DOIUrl":"https://doi.org/10.4068/cmj.2024.60.3.147","url":null,"abstract":"<p><p>Prescribing a P2Y12 inhibitor for patients with diabetes mellitus (DM) and acute myocardial infarction (AMI) who have undergone percutaneous coronary intervention (PCI) is challenging because of the risk of bleeding and ischemia. We compared the risk of ischemia and bleeding between clopidogrel and ticagrelor in elderly East Asian patients with diabetes using the Korea Acute Myocardial Infarction Registry (KAMIR)-V data. This study included 838 patients enrolled in the KAMIR-V who were >75 years, had DM, AMI, and had undergone PCI. The patients were divided into two groups based on the treatment drug. After propensity score matching, 466 patients (ticagrelor: clopidogrel= 233:233) were included in the Cox regression analyses to determine the risk of bleeding and ischemia. The baseline characteristics were not different. The type of antiplatelet therapy did not affect the incidence of Bleeding Academic Research Consortium type ≥2 bleeding. There was no significant difference between ticagrelor and clopidogrel treatment outcomes with respect to ischemia risk. This prospective study of a Korean patient cohort (elderly Korean patients with DM) showed no differences in bleeding and ischemia risks based on the use of either ticagrelor or clopidogrel. Large scale randomized controlled trials are warranted to determine the optimal antiplatelet agents for these patients.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 3","pages":"147-154"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458316/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2024-09-01Epub Date: 2024-09-25DOI: 10.4068/cmj.2024.60.3.155
Fatemeh Lohrasebi, Mousa Alavi, Mohammad Akbari, Jahangir Maghsoudi
{"title":"Design, Implementation and Evaluation of a Health Promotion Program for Family Caregivers of Chronic Mental Disorders: A Mixed Methods Study.","authors":"Fatemeh Lohrasebi, Mousa Alavi, Mohammad Akbari, Jahangir Maghsoudi","doi":"10.4068/cmj.2024.60.3.155","DOIUrl":"https://doi.org/10.4068/cmj.2024.60.3.155","url":null,"abstract":"<p><p>Family caregivers of patients with chronic mental disorders who are responsible for taking care of the patient face many problems that can endanger the psychosocial health of these people. This study was conducted to develop, implement, and evaluate a psychosocial health promotion program for family caregivers of patients with chronic mental disorders. This research is an exploratory sequential mixed-method study conducted using a qualitative-quantitative design. A qualitative study was conducted to explain the needs and psychosocial problems and the solution to improve the psychosocial health of family caregivers of patients with chronic mental disorders in two psychiatric care centers in Isfahan were conducted. Then the program was written based on Kern's programming development approach. In the quantitative stage, a part of the developed program was implemented as virtual group psychoeducation for 67 caregivers, and its impact on caregivers' burden of care was evaluated. The findings from the qualitative phase of the study led to the emergence of 3 main categories and the findings from the quantitative phase of the study indicated that the implementation of the compiled program causes a significant reduction in the burden of care in family caregivers of chronically mentally ill patients (p<0.05). The current program was prepared and developed using an evidence-based approach. Policymakers and members of the mental health team can take a valuable step toward reducing the care burden of family caregivers of chronic mental patients by using the content of the developed mental health promotion program.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 3","pages":"155-165"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Beaver Tail Liver: A Morphological Study of Variation in the Left Lobe of the Liver.","authors":"Hetal Hareshkumar Modi, Hiteshkumar Muktilal Chauhan, Himanshu Kantibhai Prajapati, Jinesh Baldevbhai Rathod","doi":"10.4068/cmj.2024.60.3.187","DOIUrl":"https://doi.org/10.4068/cmj.2024.60.3.187","url":null,"abstract":"<p><p>The liver, the largest gland in a wedge-shape, is situated in the right hypochondrium, and exhibits variation in its lobes. Knowledge of variations in the lobes of the liver is crucial for accurate radiological diagnosis and successful abdominal surgeries. The elongation of the left lobe of the liver has gained significant attention in segmentectomy and liver transplant surgeries. During October and November 2023, cross-sectional observational research was done on 53 human cadaveric liver specimens obtained from different medical colleges in Gujarat, India. The livers were meticulously examined to determine the prevalence of Beaver tail liver and measurements such as length, breadth, and thickness were recorded and statistically analyzed. The study revealed that out of the 53 livers examined, 29 (54.72%) were classified as normal, while 19 (35.85%) fell into Netter's type 2 to 7 based on Netter's classification. Interestingly, 5 (09.43%) livers exhibited an elongated left lobe, referred to as a \"sliver liver,\" which did not fit into any of the Netter's types. The beaver tail liver was found to be longer and broader compared to normal liver of the same size and weight (p<0.001). This study highlights the wide range of variations that can be observed in the lobes of the liver. The findings of this study will serve as a valuable resource for radiologists, anatomists, and surgeons, aiding them in accurate diagnoses and surgical procedures, thus minimizing the risk of misdiagnosis.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 3","pages":"187-191"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396582","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2024-09-01Epub Date: 2024-09-25DOI: 10.4068/cmj.2024.60.3.141
Zahra Eslami, Hamidreza Joshaghani
{"title":"Investigating the Role of Serotonin Levels in Cognitive Impairments Associated with Long COVID-19.","authors":"Zahra Eslami, Hamidreza Joshaghani","doi":"10.4068/cmj.2024.60.3.141","DOIUrl":"https://doi.org/10.4068/cmj.2024.60.3.141","url":null,"abstract":"<p><p>This study aimed to investigate the activation of the inflammation process, triggered as an immune response to combat the invasion by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 is a highly transmissible and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute respiratory disease, named 'coronavirus disease 2019' (COVID-19). Several mechanisms contribute to the reduction in serotonin levels, such as the impaired absorption of dietary tryptophan, hindered serotonin transport via platelets, and increased activity of an enzyme responsible for breaking down serotonin. Individuals seeking treatment for long COVID-19 had lower serotonin levels in their blood than those who had fully recovered from the infection. Furthermore, patients with long COVID-19 also had reduced tryptophan levels. The potential benefits of dietary supplementation with tryptophan or the use of selective serotonin reuptake inhibitors (SSRIs) to improve cognitive impairments and depressive and anxiety disorders in long-term COVID-19 patients. The findings support the immune response's pivotal role in modulating serotonin levels and further highlight the intricate connection between the immune system and neurotransmitter regulation.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 3","pages":"141-146"},"PeriodicalIF":0.0,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458317/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2024-05-01Epub Date: 2024-05-24DOI: 10.4068/cmj.2024.60.2.131
Young Jae Ki, Sung Soo Kim, In Young Choi, Hyun Kuk Kim, Dong Hyun Choi, Keun Ho Park
{"title":"Left Bundle Branch-Optimized Cardiac Resynchronization Therapy Using Stylet-Driven Pacing Leads with a Steerable Delivery Sheath in Patients with Atrial Fibrillation Accompanied by Slow Ventricular Response.","authors":"Young Jae Ki, Sung Soo Kim, In Young Choi, Hyun Kuk Kim, Dong Hyun Choi, Keun Ho Park","doi":"10.4068/cmj.2024.60.2.131","DOIUrl":"10.4068/cmj.2024.60.2.131","url":null,"abstract":"","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 2","pages":"131-133"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11148303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chonnam medical journalPub Date : 2024-05-01Epub Date: 2024-05-24DOI: 10.4068/cmj.2024.60.2.113
Samira Karbasi, Saman Seyedabadi, Samira Mozaffari, Zahra Foroutan, Gordon A Ferns, Asghar Zarban, Afsane Bahrami
{"title":"Curcuminoid-Piperine Combination Improves Radical Scavenging Activity in Women with Premenstrual Syndrome and Dysmenorrhea: A Post-hoc Analysis of a Randomized Clinical Study.","authors":"Samira Karbasi, Saman Seyedabadi, Samira Mozaffari, Zahra Foroutan, Gordon A Ferns, Asghar Zarban, Afsane Bahrami","doi":"10.4068/cmj.2024.60.2.113","DOIUrl":"10.4068/cmj.2024.60.2.113","url":null,"abstract":"<p><p>Oxidative stress maybe involved in the patho-etiology of menstrual-associated complications. Curcuminoids, are polyphenolic natural compounds that have potentially important functional activities. This triple-blind, randomized, placebo-controlled trial was performed to investigate the effects of a curcuminoids on oxidative stress and antioxidant capacity in girls with premenstrual syndrome (PMS) and dysmenorrhea. Eighty young girls with both PMS and dysmenorrhea were randomly given either curcuminoids (500 mg+5 mg piperine) or a placebo daily, for a period from 7 days pre- until 3 days post- initiation of menstrual bleeding for 3 successive menstrual cycles. The total antioxidant capacity and free radical scavenging activity of serum and urine were quantified via ferric reducing/antioxidant power (FRAP) and 1,1-diphenyl-2-picrylhydrazyl (DPPH) methods, respectively. There were no significant differences between the placebo and curcumin groups, with respect to the age, dietary intake and biochemical/anthropometric indices (p>0.05). The curcumin treatment significantly increased the free-radical scavenging activity of serum compared to the treatment with placebo (p=0.031). Although, no significant changes were found in serum and urinary levels of FRAP, DPPH and MDA between the groups (p>0.05). Curcumin treatment did increase free-radical scavenging activity and antioxidant potential in girls with PMS and dysmenorrhea. Investigations with higher doses and duration of curcumin are required to verify our findings.</p>","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"60 2","pages":"113-119"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11148302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141263446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}