Chonnam medical journal最新文献_第9页

Helicobacter pylori Eradication-Related Development of Multiple White and Flat Elevated Lesions in the Stomach. 幽门螺杆菌根除相关的胃多发白色和扁平隆起病变的发展。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.203

Akira Hokama, Mayumi Shiroma, Mami Tomiyama, Yuko Tasato, Maki Setake

引用次数: 0

A Successful Case of Radiofrequency Ablation of Multiple Accessory Pathways in Ebstein's Anomaly Using Intracardiac Echocardiography. 心内超声心动图射频消融术治疗Ebstein畸形的一例成功病例。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.209

Hyun Kuk Kim, Sung Soo Kim, In Young Choi, Young Jae Ki, Dong Hyun Choi, Keun Ho Park

引用次数: 0

Pancreaticoduodenal Artery Aneurysm due to Median Arcuate Ligament Compression of the Celiac Artery. 腹腔动脉正中弓形韧带压迫引起的胰十二指肠动脉瘤。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.200

Keizo Tanitame

引用次数: 0

Rivaroxaban: A Rare Cause of Spontaneous Bilateral Adrenal Haematomas. 利伐沙班：自发性双侧肾上腺血肿的罕见病因。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.196

Preet Mukesh Shah, Robert D Murray

引用次数: 0

Mechanistic Insight into Age-Related Macular Degeneration (AMD): Anatomy, Epidemiology, Genetics, Pathogenesis, Prevention, Implications, and Treatment Strategies to Pace AMD Management. 年龄相关性黄斑变性（AMD）的机制洞察：解剖学、流行病学、遗传学、发病机制、预防、意义和治疗策略对AMD管理的影响。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.143

Mohammad Amin Amini, Ashkan Karbasi, Mohammad Vahabirad, Masoud Khanaghaei, Aida Alizamir

{"title":"Mechanistic Insight into Age-Related Macular Degeneration (AMD): Anatomy, Epidemiology, Genetics, Pathogenesis, Prevention, Implications, and Treatment Strategies to Pace AMD Management.","authors":"Mohammad Amin Amini, Ashkan Karbasi, Mohammad Vahabirad, Masoud Khanaghaei, Aida Alizamir","doi":"10.4068/cmj.2023.59.3.143","DOIUrl":"10.4068/cmj.2023.59.3.143","url":null,"abstract":"One of the most complicated eye disorders is age-related macular degeneration (AMD) which is the leading cause of irremediable blindness all over the world in the elderly. AMD is classified as early stage to late stage (advanced AMD), in which this stage is divided into the exudative or neovascular form (wet AMD) and the nonexudative or atrophic form (dry AMD). Clinically, AMD primarily influences the central area of retina known as the macula. Importantly, the wet form is generally associated with more severe vision loss. AMD has a systemic component, where many factors, like aging, genetic, environment, autoimmune and non-autoimmune disorders are associated with this disease. Additionally, healthy lifestyles, regular exercise, maintaining a normal lipid profile and weight are crucial to decreasing the risk of AMD. Furthermore, therapeutic strategies for limiting AMD should encompass a variety of factors to avoid and improve drug interventions, and also need to take into account personalized genetic information. In conclusion, with the development of technology and research progress, visual impairment and legal blindness from AMD have been substantially reduced in incidence. This review article is focused on identifying and developing the knowledge about the association between genetics, and etiology with AMD. We hope that this review will encourage researchers and lecturers, open new discussions, and contribute to a better understanding of AMD that improves patients' visual acuity, and upgrades the quality of life of AMD patients.","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"143-159"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/39/9a/cmj-59-143.PMC10570864.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diffusion Weighted Imaging in a Patient with Transient Global Amnesia. 一例短暂性整体失忆患者的扩散加权成像。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.205

Keizo Tanitame, Hayato Araki

引用次数: 0

Complement Regulatory Protein CD46 Manifests a Unique Role in Promoting the Migration of Bladder Cancer Cells. 补体调节蛋白CD46在促进膀胱癌症细胞迁移中发挥独特作用。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.160

Thuy Thi Nguyen, Hien Duong Thanh, Manh-Hung Do, Chaeyong Jung

{"title":"Complement Regulatory Protein CD46 Manifests a Unique Role in Promoting the Migration of Bladder Cancer Cells.","authors":"Thuy Thi Nguyen, Hien Duong Thanh, Manh-Hung Do, Chaeyong Jung","doi":"10.4068/cmj.2023.59.3.160","DOIUrl":"10.4068/cmj.2023.59.3.160","url":null,"abstract":"CD46 is a membrane-bound complement regulatory protein (mCRP) possessing a regulatory role with the complement system. CD46 protects the host cells from damage by complement. Expression of CD46 is also highly maintained in many cancers, including bladder cancers, and thus functions as a receptor for many cancer therapeutic viruses. In this study we report a unique role of CD46 as a progression factor of cancer cells in bladder cancers. Resulting data from a DNA microarray using CD46-altered HT1376 bladder cancers demonstrated a pool of target genes, including complement C3 α chain (C3α), matrix Gla protein (MGP), AFAP-AS1, follicular dendritic cell secreted protein (FDCSP), MAM domain containing 2 (MAMDC2), gamma-aminobutyric acid A receptor pi (GABRP), transforming growth factor, beta-induced (TGFBI), a family of cytochrome P450 (CYP24A1), sialic acid binding Ig-like lectin 6 (SIGLEC6), metallothionein 1E (MT1E), and several members of cytokeratins. Subsequent studies using quantitative RT-PCR and Western blot analyses confirmed CD46-mediated regulation of C3α, MGP, and keratin 13 (KRT13). MGP and KRT13 are known to be involved in cell migration and cancer cell metastasis. A cell migration assay demonstrated that CD46 enhanced migratory potential of bladder cancer cells. Taken all together, this report demonstrated that CD46 is generally overexpressed in bladder cancers and plays a unique role in the promotion of cancer cell migration. Further detailed studies are needed to be performed to clarify the action mechanism of CD46 and its application to cancer therapeutics.","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"160-166"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/cc/7e/cmj-59-160.PMC10570858.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Fungating Breast Cancer with Metastasis in a Developed Country: A Caveat to Our Strategy. 发达国家真菌性癌症转移：我们战略的一个启示。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.194

Justine Chinnappan, Huda Marcus, Thair Dawood, Ghassan Bachuwa

引用次数: 0

Ileal Perforation Caused by Metastasis of Breast Carcinoma. 乳腺癌转移引起的回肠穿孔。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.198

Daijiro Kagawa, Mikako Kotani, Takao Miyaguni, Tomofumi Chibana, Ippei Uezu, Yoshiki Chinen, Kanetaka Maeshiro, Ryoko Ono, Masayoshi Nagahama, Izumi Kinjo, Hirofumi Tomori, Hiroshi Miyazato, Kyoko Arakaki, Akira Hokama

引用次数: 0

The Boosting Effects of Melatonin on the In Vitro Fertilization (IVF) of Women with Polycystic Ovary Syndrome. 褪黑素对多囊卵巢综合征妇女体外受精（IVF）的促进作用。

Chonnam medical journal Pub Date : 2023-09-01 Epub Date: 2023-09-25 DOI: 10.4068/cmj.2023.59.3.188

Shamim Pilehvari, Mahnaz Yavangui, Elham Paknahad, Zahra Cheraghi, Marzieh Ghorbani

{"title":"The Boosting Effects of Melatonin on the In Vitro Fertilization (IVF) of Women with Polycystic Ovary Syndrome.","authors":"Shamim Pilehvari, Mahnaz Yavangui, Elham Paknahad, Zahra Cheraghi, Marzieh Ghorbani","doi":"10.4068/cmj.2023.59.3.188","DOIUrl":"10.4068/cmj.2023.59.3.188","url":null,"abstract":"Polycystic ovary syndrome (PCOS) is one of the most critical disorders, which affects approximately 20% of women of childbearing age and melatonin supplementation in these women can be effective. However, human studies in this area are particularly limited to IVF candidates. The aim of this clinical trial study was to evaluate the effect of melatonin on the in vitro fertilization (IVF) in PCOS involved women. In this clinical trial study, a total of 320 women with PCOS were randomly assigned to the intervention and control groups. Patients in the intervention group (n=160) received a combination of melatonin and metformin (3 mg and 500 mg, respectively) three times a day. The control group (n=160) received metformin 500 mg from the luteal phase of the cycle before the start of gonadotropin. Oocyte and embryo quality, number of oocytes, and pregnancy outcomes were compared in both groups. Our study revealed that the frequency of Metaphase II oocytes (69.9% vs. 57.9%, p<0.001) and the number of embryos of the top-quality (grade A) were higher in the group treated with melatonin (40.3% vs. 29.9%, p=0.001). The rate of clinical pregnancy and implantation were also higher in the intervention group. The odds of clinical pregnancy in the intervention group was 1.8 times (p=0.039). Moreover, oral melatonin supplementation was effective in patients with PCOS, who were candidates for IVF because of the increased quality of mature oocytes, top-quality embryos, and increased odds of clinical pregnancy.","PeriodicalId":94372,"journal":{"name":"Chonnam medical journal","volume":"59 3","pages":"188-193"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/50/d0/cmj-59-188.PMC10570865.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41242960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0