Revista clinica espanola最新文献_第8页

Association between serum α-Klotho levels and osteoarthritis prevalence among middle-aged and older adults: an analysis of the NHANES 2007–2016 血清 α-Klotho 水平与中老年人骨关节炎患病率之间的关系：对 2007-2016 年国家健康调查（NHANES）的分析

Revista clinica espanola Pub Date : 2024-06-01 DOI: 10.1016/j.rceng.2024.04.012

Qi Xu , jiale Wang , Hanzhi Li , Yuwan Gao

{"title":"Association between serum α-Klotho levels and osteoarthritis prevalence among middle-aged and older adults: an analysis of the NHANES 2007–2016","authors":"Qi Xu , jiale Wang , Hanzhi Li , Yuwan Gao","doi":"10.1016/j.rceng.2024.04.012","DOIUrl":"10.1016/j.rceng.2024.04.012","url":null,"abstract":"<div><h3>Background</h3><p>As individuals age, the prevalence of osteoarthritis tends to increase gradually. α-Klotho is a hormone renowned for its anti-aging properties. However, the precise role of serum α-Klotho in osteoarthritis is still not fully comprehended.</p></div><div><h3>Methods</h3><p>We conducted a cross-sectional study utilizing data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2007 to 2016. Serum α-Klotho levels were measured using an enzyme-linked immunosorbent assay (ELISA). Osteoarthritis was assessed through self-reported questionnaires. Through univariate and multivariate logistic regression analyses, smooth curve fitting, threshold effect analysis, and subgroup analyses, we delved into the potential association between them.</p></div><div><h3>Results</h3><p>The study encompassed a cohort of 10,265 participants. In fully adjusted models of multivariate logistic regression analysis, we identified a negative correlation between serum ln α-Klotho and OA (OR = 0.77, 95% CI: 0.65−0.91, p = 0.003). When stratifying serum α-Klotho levels into tertiles, individuals in the highest tertile exhibited a 26% reduced risk of OA compared to those in the lowest tertile (OR = 0.84, 95% CI: 0.73−0.97, p = 0.014). Subsequent analyses indicated a linearly negative association. In subgroup analyses, we explored the relationship between serum ln α-Klotho and osteoarthritis across diverse populations, revealing the persistence of this association in the majority of subgroups.</p></div><div><h3>Conclusion</h3><p>Serum α-Klotho levels exhibit a significant negative linear correlation with the prevalence of osteoarthritis in middle-aged and elderly populations in the United States.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 6","pages":"Pages 366-378"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140767765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative performance of vulvovaginal swab sampling versus endocervical sampling for the detection of Chlamydia, Gonorrhea, Mycoplasma genitalium, and Trichomoniasis: a cross-sectional study in Spain 外阴拭子取样与宫颈内膜取样在检测衣原体、淋病、生殖器支原体和滴虫病方面的性能比较：西班牙的一项横断面研究

Revista clinica espanola Pub Date : 2024-06-01 DOI: 10.1016/j.rceng.2024.04.015

M. Linares , P. Galicia , A. Rojas , A. Miguel-Benito , J. Cuadros-González , J.M. Ramos-Rincón

{"title":"Comparative performance of vulvovaginal swab sampling versus endocervical sampling for the detection of Chlamydia, Gonorrhea, Mycoplasma genitalium, and Trichomoniasis: a cross-sectional study in Spain","authors":"M. Linares , P. Galicia , A. Rojas , A. Miguel-Benito , J. Cuadros-González , J.M. Ramos-Rincón","doi":"10.1016/j.rceng.2024.04.015","DOIUrl":"10.1016/j.rceng.2024.04.015","url":null,"abstract":"<div><h3>Introduction</h3><p>The global increase in sexual transmitted infections (STI) makes it necessary to seek public health strategies that facilitate rapid and minimally invasive diagnosis. The objective was to evaluate the concordance between vaginal and endocervical samples for STI diagnosis.</p></div><div><h3>Materials and methods</h3><p>A retrospective cross-sectional study was carried out on vaginal and endocervical samples from women attended in our reference area with symptoms suggestive of vulvovaginitis or for STI screening during the study period.</p></div><div><h3>Results</h3><p>A total of 130 paired samples were analyzed; fifty-seven and 59 samples were positive for vaginal and endocervical specimens (Kappa index of 0.969 (Standard error = 0.022). The sensitivity of the vaginal samples was 96.5% (IC95%: 87.2–99.4), with a specificity of 100% (IC95%: 93.0–100).</p></div><div><h3>Discussion</h3><p>The introduction of STI screening in vaginal samples in our environment can facilitate rapid and effective diagnosis and allow early treatment of STI. Additionally, it facilitates sample collection and diagnosis in the community setting, essential for optimal screening.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 6","pages":"Pages 393-397"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140866523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

External validation of the EFFECT mortality prediction scale in patients admitted for acute heart failure in Araba, Spain 对西班牙阿拉巴地区急性心力衰竭住院患者的 EFFECT 死亡率预测量表进行外部验证。

Revista clinica espanola Pub Date : 2024-06-01 DOI: 10.1016/j.rceng.2024.05.004

S. Goya-Lirio , M. Hernando-Llorens , S. García de Garayo-Díaz , J. Regalado-de Los Cobos

{"title":"External validation of the EFFECT mortality prediction scale in patients admitted for acute heart failure in Araba, Spain","authors":"S. Goya-Lirio , M. Hernando-Llorens , S. García de Garayo-Díaz , J. Regalado-de Los Cobos","doi":"10.1016/j.rceng.2024.05.004","DOIUrl":"10.1016/j.rceng.2024.05.004","url":null,"abstract":"<div><h3>Aim</h3><p>To validate the EFFECT (Enhanced Feedback for Effective Cardiac Treatment) scales, which predict mortality at 1 month and 1 year after admission, in a defined cohort of patients admitted to the Araba University Hospital (HUA) with a diagnosis of acutely decompensated heart failure.</p></div><div><h3>Method</h3><p>External validation study of a predictive model, in a retrospective cohort of patients admitted between October 1, 2020 and September 30, 2021.</p></div><div><h3>Results</h3><p>A total of 550 patients were included. The two scales demonstrated good overall discriminatory ability in our series, with an area under ROC (0.755 y 0.756) and values in Brier score (0.094 y 0.194) similar to the original series. Calibration was assessed using the Hosmer-Lemeshow test and calibration plots and was also adequate. All this despite the fact that significant differences were observed in many clinical characteristics between our series and the original one.</p></div><div><h3>Conclusions</h3><p>The EFFECT scales showed good predictive ability and transportability. The one-month prediction scale was also useful for predicting mortality at one year. For both time periods, mortality was similar in the groups established in the original as low and very low risk.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 6","pages":"Pages 379-386"},"PeriodicalIF":0.0,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141094850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determining factors of pulse oximetry accuracy: a literature review 脉搏氧饱和度准确性的决定因素：文献综述。

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.005

D. León-Valladares , L.A. Barrio-Mateu , N. Cortés-Carmona , G. Fuentes-Lizana , A.M. Cabanas , K. Latorre-Progulakis , M. Fuentes-Guajardo , P. Martín-Escudero

{"title":"Determining factors of pulse oximetry accuracy: a literature review","authors":"D. León-Valladares , L.A. Barrio-Mateu , N. Cortés-Carmona , G. Fuentes-Lizana , A.M. Cabanas , K. Latorre-Progulakis , M. Fuentes-Guajardo , P. Martín-Escudero","doi":"10.1016/j.rceng.2024.04.005","DOIUrl":"10.1016/j.rceng.2024.04.005","url":null,"abstract":"<div><h3>Objective</h3><p>Identify and reach consensus on the variables that affect the measurement of oxygen saturation using pulse oximetry.</p></div><div><h3>Methods</h3><p>We applied inclusion and exclusion criteria to select relevant studies in databases such as Ebsco and PubMed. The search strategies, carried out until December 2023, focused on publications that addressed the technology of pulse oximeters and variables that influence their accuracy. We assessed the risk of bias of the included studies and used standardized methods for synthesis of results.</p></div><div><h3>Results</h3><p>23 studies were included. The synthesis of the results highlighted that equipment with tetrapolar technology showed greater precision in oxygen saturation measurements. Increased skin pigmentation, hemoglobinopathies and high skin temperatures can lead to an overestimation of SpO<sub>2</sub>, while factors such as low perfusion, cold skin temperature, nail polish or tattoos, hypoxemia, anemia and high altitude training, they may underestimate it. On the other hand, motion artifacts, light pollution, frequency >150 beats per minute, electromagnetic interference and location of the sensor can cause distortion of the photoplethymography signal.</p></div><div><h3>Conclusions</h3><p>The synthesis of the results highlighted that skin pigmentation and light interference can lead to an overestimation of SpO<sub>2</sub>, while other factors such as low perfusion and altitude tend to underestimate it. The studies presented variability and heterogeneity in their designs, evidencing limitations in the consistency and precision of the evidence. Despite these limitations, the results underscore the importance of considering multiple variables when interpreting pulse oximetry measurements to ensure their reliability. The findings have significant implications for clinical practice and future research.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 314-330"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140779730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Internal carotid artery bulb width: a novel potential parameter for the prediction of cerebral vascular diseases 颈内动脉球宽度：预测脑血管疾病的潜在新参数。

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.008

İ. Ökçesiz , H. Dönmez , M.M. Etleç , A. Öztürk

{"title":"Internal carotid artery bulb width: a novel potential parameter for the prediction of cerebral vascular diseases","authors":"İ. Ökçesiz , H. Dönmez , M.M. Etleç , A. Öztürk","doi":"10.1016/j.rceng.2024.04.008","DOIUrl":"10.1016/j.rceng.2024.04.008","url":null,"abstract":"<div><h3>Objective</h3><p>To investigate the relationship between the width of the internal carotid artery (ICA) bulb and cerebral vascular diseases including stroke and intracranial aneurysms.</p></div><div><h3>Material and methods</h3><p>In total 300 patients who had supra-aortic computed tomography angiography (CTA) were enrolled in this study from 2015 to 2021. The study groups consisted of 100 ischemic stroke patients, 100 patients with intracranial aneurysms, and 100 control subjects. The intracranial aneurysm patient group was divided into two subgroups according to the presence of subarachnoid hemorrhage (SAH). The largest diameters of the ICA C1 (cervical) and C2 (petrous) segments in all individuals were measured bilaterally on CTA images. The ICA diameter ratios of the cases were measured using the formula <span><math><mfrac><mrow><mi>C</mi><mn>1</mn><mo>-</mo><mi>C</mi><mn>2</mn></mrow><mrow><mtext>C</mtext><mn>1</mn></mrow></mfrac></math></span>. The relationship between the age and ICA vessel analysis was evaluated as well.</p></div><div><h3>Results</h3><p>The mean ICA bulb width values in the ischemic stroke patient group and the intracranial aneurysm patient group were significantly higher than the control group (<em>p</em> < 0.001). The ICA C1 and C2 segment diameter values and ICA diameter ratio were smaller in the intracranial aneurysm patients with SAH than those who had not (<em>p</em> = 0.7). There was a statistically significant but weak relationship between the age and ICA diameter ratios in all study groups (R-squared value of 0.26, <em>p</em> = 0.03).</p></div><div><h3>Conclusion</h3><p>ICA bulb width is a parameter that can be easily evaluated with neuroimaging modalities and is a successful method that may be used for predicting the risk of ischemic stroke or the presence of an intracranial aneurysm.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 267-271"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140765093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Severe cardiovascular events among spectators of Spanish professional soccer league before and after COVID-19 onset 西班牙职业足球联赛观众在 COVID-19 启用前后发生的严重心血管事件。

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.001

L. Consuegra-Sánchez , J.A. Martínez

引用次数: 0

Clinical suspicion, diagnosis and management of cardiac amyloidosis: update document and executive summary 心脏淀粉样变性的临床怀疑、诊断和管理：更新文件和执行摘要。

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.009

S. Yun , J. Casado , J. Pérez-Silvestre , P. Salamanca , P. Llàcer , R. Quirós , R. Ruiz-Hueso , M. Méndez , L. Manzano , F. Formiga

引用次数: 0

Impact of hypochloremia as a prognostic factor in patients with heart failure, a retrospective cohort study 低氯化物血症作为心力衰竭患者预后因素的影响，一项回顾性队列研究。

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.003

P. de Peralta García , M. Bolzoni , M. Yebra Yebra , M. Asenjo Martín , M. Arrondo Turrado , M.A. Domínguez Sepúlveda , J.A. Rueda Camino , R. Barba Martín

{"title":"Impact of hypochloremia as a prognostic factor in patients with heart failure, a retrospective cohort study","authors":"P. de Peralta García , M. Bolzoni , M. Yebra Yebra , M. Asenjo Martín , M. Arrondo Turrado , M.A. Domínguez Sepúlveda , J.A. Rueda Camino , R. Barba Martín","doi":"10.1016/j.rceng.2024.04.003","DOIUrl":"10.1016/j.rceng.2024.04.003","url":null,"abstract":"<div><h3>Background</h3><p>some studies suggest that hypochloremia is a risk factor in the prognosis of heart failure (HF) in patients with recent decompensation.</p></div><div><h3>Materials and methods</h3><p>retrospective cohort study of patients discharged due to HF decompensation who began follow-up in a specialized clinic. Two groups are defined: patients with hypochloremia (chloride < 98 mmol/L) and normochloremic patients (chloride > 98 mmol/L) in the initial assessment within the first month after discharge. The rate of intravenous diuretic rescue, emergency department visits, readmission for HF and cardiovascular (CV) death are compared using a Cox proportional hazards model.</p></div><div><h3>Results</h3><p>165 patients were included (59% women, mean age 85 years), with 60 (36%) having hypochloremia. Both groups were comparable in terms of baseline characteristics, except for female sex, presence of peripheral artery disease, moderate-to-severe liver disease (more prevalent in the hypochloremia group), PROFUND index, and baseline furosemide dose (higher in patients with hypochloremia). The incidence of the primary event was higher in subjects with hypochloremia than in normochloremic subjects (HR: 1.59, 95% CI 0.97–2.62), mainly due to the need for intravenous diuretic rescue (HR: 1.86, 95% CI 1.07−3.24).</p></div><div><h3>Conclusions</h3><p>hypochloremia following admission for HF decompensation is associated with a greater need for intravenous diuretic rescue therapy and probably worse overall prognosis across the spectrum of the disease, regardless of left ventricular ejection fraction (LVEF).</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 259-266"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140790100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the expression of the Serpina1 gene in SARS-CoV-2 infection: study of a new biomarker Serpina1基因在SARS-CoV-2感染中的表达分析：研究一种新的生物标志物

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.006

M. Pintanel-Raymundo , S. Menao-Guillén , J.J. Perales-Afán , A. García-Gutiérrez , I. Moreno-Gázquez , M. Julián-Ansón , M. Ramos-Álvarez , S. Olivera-González , I. Gutiérrez-Cía , M.A. Torralba-Cabeza

{"title":"Analysis of the expression of the Serpina1 gene in SARS-CoV-2 infection: study of a new biomarker","authors":"M. Pintanel-Raymundo , S. Menao-Guillén , J.J. Perales-Afán , A. García-Gutiérrez , I. Moreno-Gázquez , M. Julián-Ansón , M. Ramos-Álvarez , S. Olivera-González , I. Gutiérrez-Cía , M.A. Torralba-Cabeza","doi":"10.1016/j.rceng.2024.04.006","DOIUrl":"10.1016/j.rceng.2024.04.006","url":null,"abstract":"<div><h3>Introduction</h3><p>The <em>SERPINA1</em> gene encodes the protein Alpha-1 Antitrypsin (AAT1). Possible imbalances between the concentrations of proteases and antiproteases (AAT1) can lead to the development of serious pulmonary and extrapulmonary pathologies. In this work we study the importance of this possible imbalance in patients with COVID-19.</p></div><div><h3>Objectives</h3><p>To correlate the severity of the symptoms of SARS-COV-2 infection with the AAT1 concentrations at diagnosis of the disease.</p></div><div><h3>Methods</h3><p>An observational, prospective, cross-sectional, non-interventional, analytical study was carried out where 181 cases with COVID-19 admitted to the “Lozano Blesa” University Clinical Hospital of Zaragoza were selected. The concentration of AAT1 was studied in all of them and this was correlated with the clinical aspects and biochemical parameters at hospital admission.</p></div><div><h3>Results</h3><p>141 cases corresponded to patients with severe COVID and 40 patients with mild COVID. AAT1 levels were positively correlated with the days of hospitalization, severity, C-Reactive Protein, ferritin, admission to Intensive Care, and death, and presented a negative correlation with the number of lymphocytes/mm3. AAT1 concentrations higher than 237.5 mg/dL allowed the patient to be classified as “severe” (S72%; E78%) and 311.5 mg/dL were associated with the risk of admission to Intensive Care or Exitus (S67%; E79%).</p></div><div><h3>Conclusions</h3><p>Levels of the SERPINA1 gene expression product, AAT1, correlate with the severity of COVID-19 patients at diagnosis of the disease, being useful as a prognostic biomarker.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 253-258"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140756690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

PICO questions and DELPHI methodology for improving the management of patients with acute hepatic porphyria 改善急性肝性卟啉症患者管理的 PICO 问题和 DELPHI 方法。

Revista clinica espanola Pub Date : 2024-05-01 DOI: 10.1016/j.rceng.2024.04.010

A. Riera-Mestre , J.S. García Morillo , J. Castelbón Fernández , M.E. Hernández-Contreras , P. Aguilera Peiró , J. Jacob , F. Martínez Valle , E. Guillén-Navarro , M. Morales-Conejo

{"title":"PICO questions and DELPHI methodology for improving the management of patients with acute hepatic porphyria","authors":"A. Riera-Mestre , J.S. García Morillo , J. Castelbón Fernández , M.E. Hernández-Contreras , P. Aguilera Peiró , J. Jacob , F. Martínez Valle , E. Guillén-Navarro , M. Morales-Conejo","doi":"10.1016/j.rceng.2024.04.010","DOIUrl":"10.1016/j.rceng.2024.04.010","url":null,"abstract":"<div><h3>Background</h3><p>Acute hepatic porphyrias (AHPs) are a group of rare diseases that encompasses acute intermittent porphyria, variegate porphyria, hereditary coproporphyria, and 5-aminolaevulinic acid dehydratase deficiency porphyria. Symptoms of AHP are nonspecific which, together with its low prevalence, difficult the diagnosis and follow-up of these patients.</p></div><div><h3>Material and methods</h3><p>This project used DELPHI methodology to answer PICO questions related to management of patients with AHPs. The objective was to reach a consensus among multidisciplinary porhyria experts providing answers to those PICO questions for improving diagnosis and follow-up of patients with AHP.</p></div><div><h3>Results</h3><p>Ten PICO questions were defined and grouped in four domains: 1. Biochemical diagnosis of patients with AHP. 2. Molecular tests for patients with AHP. 3. Follow-up of patients with AHP. 4. Screening for long-term complications of patients with AHP.</p></div><div><h3>Conclusions</h3><p>PICO questions and DELPHI methodology have provided a consensus on relevant and controversial issues for improving the management of patients with AHP.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 272-280"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140758081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0