M. del Carmen Gamero-Sánchez , I. Barreto , J.C. Arévalo-Lorido , E. Vázquez-Jarén , J. Maese-Calvo , N. Mayoral-Testón , J. Carretero-Gómez , D. Fernández-Bergés
{"title":"Multidimensional frailty connection in older patients with diabetes mellitus","authors":"M. del Carmen Gamero-Sánchez , I. Barreto , J.C. Arévalo-Lorido , E. Vázquez-Jarén , J. Maese-Calvo , N. Mayoral-Testón , J. Carretero-Gómez , D. Fernández-Bergés","doi":"10.1016/j.rceng.2024.04.007","DOIUrl":"10.1016/j.rceng.2024.04.007","url":null,"abstract":"<div><h3>Background and objective</h3><p>Patients with diabetes mellitus (DM) experience accelerated aging and, thus, a high prevalence of frailty. Our aim is to outline the type of frailty and prefrailty from a multidimensional perspective and the interaction of these dimensions in this scenery.</p></div><div><h3>Material and methods</h3><p>Observational study of patients with DM over 60 years-old. Variables related to nutrition, cognitive and emotional status, physical and instrumental functional capacity and social resources were collected. They were divided into three groups (robust, prefrail and frail) according to the Fried scale. Each of the variables in the groups were compared and a correspondence analysis was carried out to see the influence of some dimensions with others in each stage of frailty.</p></div><div><h3>Results</h3><p>188 patients (mean age 72.6 <u>+</u> 7.5) were analysed. Of them, 105 patients had prefrailty and 66 were frail. With the exception of social resources, the rest of the variables had an increasing prevalence depending on the stage of frailty. However, in the correspondence analysis (with 22.9% of variation explained by two dimensions) it was only patients with frailty who were associated with worse functional capacity, cognitive and emotional situation and mild to moderate social incapacity.</p></div><div><h3>Conclusions</h3><p>In our sample there was a high prevalence of prefrailty, and frailty associated with an increase in the prevalence of other different dimensions except social resources. However, the interaction between these dimensions was only evident in the case of patients with frailty.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 281-287"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140789909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Gil-Díaz , J. Martín Guerra , P. Parra Caballero , G. Puche Palao , N. Muñoz-Rivas , N. Ruiz-Giménez Arrieta
{"title":"Diagnosis and treatment of deep vein thrombosis of the lower and upper limbs. 2024 recommendations of the venous thromboembolism group of the Spanish Society of Internal Medicine","authors":"A. Gil-Díaz , J. Martín Guerra , P. Parra Caballero , G. Puche Palao , N. Muñoz-Rivas , N. Ruiz-Giménez Arrieta","doi":"10.1016/j.rceng.2024.04.004","DOIUrl":"10.1016/j.rceng.2024.04.004","url":null,"abstract":"<div><p>Deep vein thrombosis (DVT) of the limbs is a common disease and causes significant morbidity and mortality. It is frequently the prelude to pulmonary embolism (PE), it can recur in 30% of patients and in 25–40% of cases they can develop post-thrombotic syndrome (PTS), with a significant impact in functional status and quality of life. This document contains the recommendations on the diagnosis and treatment of acute DVT from the Thromboembolic Disease group of the Spanish Society of Internal Medicine (SEMI).</p><p>PE and thrombosis of unusual venous territories (cerebral, renal, mesenteric, superficial, etc.) are outside its scope, as well as thrombosis associated with catheter and thrombosis associated with cancer, which due to their peculiarities will be the subject of other positioning documents of the Thromboembolic Disease group of the Spanish Society of Internal Medicine (SEMI).</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 300-313"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140784414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
María Fernanda García Aguilera , Nayely García Méndez , Edgardo Álvarez Muñoz , J. Lagarda Cuevas
{"title":"Letter to the editor on «Bioethical challenges in clinical practice of the 20th century»","authors":"María Fernanda García Aguilera , Nayely García Méndez , Edgardo Álvarez Muñoz , J. Lagarda Cuevas","doi":"10.1016/j.rceng.2024.03.004","DOIUrl":"10.1016/j.rceng.2024.03.004","url":null,"abstract":"","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 5","pages":"Pages 331-332"},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140195396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elena Urízar Ursúa, Alicia Aldea, María Bayona, Patricia M. Oliván
{"title":"Letter to the editor analysing a study about diabetes mellitus","authors":"Elena Urízar Ursúa, Alicia Aldea, María Bayona, Patricia M. Oliván","doi":"10.1016/j.rceng.2024.02.010","DOIUrl":"10.1016/j.rceng.2024.02.010","url":null,"abstract":"","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 4","pages":"Pages 251-252"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Pertusa Mataix , E. Menéndez Rivero , C. Hernández Quiles , J.S. García Morillo
{"title":"Successful desensitization to anakinra in a case with immediate cutaneous reaction in Still disease","authors":"R. Pertusa Mataix , E. Menéndez Rivero , C. Hernández Quiles , J.S. García Morillo","doi":"10.1016/j.rceng.2024.02.011","DOIUrl":"10.1016/j.rceng.2024.02.011","url":null,"abstract":"","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 4","pages":"Pages 247-249"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Carmena de la Asunción, I. Jiménez Pérez de Heredia, A. Belda Mira
{"title":"West Nile virus infection: first autochthonous case in the Community of Valencia","authors":"A. Carmena de la Asunción, I. Jiménez Pérez de Heredia, A. Belda Mira","doi":"10.1016/j.rceng.2024.03.002","DOIUrl":"10.1016/j.rceng.2024.03.002","url":null,"abstract":"","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 4","pages":"Pages 249-251"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevalence of the limited vs. extensive scleroderma-related interstitial lung disease at the time of diagnosis of SSc-ILD based on Goh et al. criteria. Systematic review and meta-analysis","authors":"Manuel Rubio-Rivas , Melani Pestaña-Fernández","doi":"10.1016/j.rceng.2024.02.008","DOIUrl":"10.1016/j.rceng.2024.02.008","url":null,"abstract":"<div><h3>Introduction</h3><p>Goh et al. proposed in 2008 a classificatory algorithm of limited or extensive SSc-ILD. The prevalence of both at the time of diagnosis of SSc-ILD is not known with exactitude.</p></div><div><h3>Methods</h3><p>The review was undertaken by means of MEDLINE and SCOPUS from 2008 to 2023 and using the terms: \"systemic\", \"scleroderma\" or \"interstitial lung disease\" [MesH]. The Newcastle-Ottawa Scale was used for the qualifying assessment for observational studies and the Jadad scale for clinical trials. The inverse variance-weighted method was performed.</p></div><div><h3>Results</h3><p>Twenty-seven studies were initially included in the systematic review and meta-analysis (SRMA). Of these, 17 studies had no overlapping data. They reported data from 2,149 patients, 1,369 (81.2%) were female. The mean age was 52.4 (SD 6.6) years. 45.2% of the patients had the diffuse subtype and 54.8% had the limited or sine scleroderma subtype. A total of 38.7% of the patients showed positive antitopoisomerase antibodies (ATA) and 14.2% positive anticentromere antibodies (ACA). The mean percentage of forced vital capacity (FVC) at baseline was 80.5% (SD 6.9) and of diffusing capacity of the lungs for carbon monoxide (DLco) was 59.1% (SD 9.6). Twelve studies presented SSc-ILD extension data adjusted for PFTs and were included in the meta-analysis. The 10 observational cohort studies were analyzed separately. The overall percentage of limited extension was estimated at 63.5% (95%CI 55.3–73; p < 0.001) using the random-effects model. Heterogeneity between studies (I<sup>2</sup>) was 9.8% (95%CI 0–68.2%) with the random-effects model. Extensive pulmonary involvement was estimated at 34.3% (95%CI 26–45.4; p < 0.001). Heterogeneity between studies (I<sup>2</sup>) was 0% (95%CI 0–61.6%) with the random-effects model.</p></div><div><h3>Conclusion</h3><p>The overall percentage of limited SSc-ILD at the time of diagnosis of SSc-ILD was estimated at 63.5% and extensive at 34.3%.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 4","pages":"Pages 189-196"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139935024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Muñoz , S. Aragón , M. Ballesteros , E. Bisbe-Vives , C. Jericó , P. Llamas-Sillero , H.M. Meijide-Míguez , E. Rayó-Martin , M.J. Rodríguez-Suárez
{"title":"Executive summary of the consensus document on the management of perioperative anemia in Spain","authors":"M. Muñoz , S. Aragón , M. Ballesteros , E. Bisbe-Vives , C. Jericó , P. Llamas-Sillero , H.M. Meijide-Míguez , E. Rayó-Martin , M.J. Rodríguez-Suárez","doi":"10.1016/j.rceng.2024.02.012","DOIUrl":"10.1016/j.rceng.2024.02.012","url":null,"abstract":"<div><p>Perioperative anemia is an independent risk factor for postoperative morbidity and mortality. However, conceptual, logistical and administrative barriers persist that hinder the widespread implementation of protocols for their management. The project coordinator convened a multidisciplinary group of 8 experienced professionals to develop perioperative anemia management algorithms, based on a series of key points (KPs) related to its prevalence, consequences, diagnosis and treatment. These KPs were assessed using a 5-point Likert scale, from \"strongly disagree [1]\" to \"strongly agree [5]\". For each KP, consensus was reached when receiving a score of 4 or 5 from at least 7 participants (>75%). Based on the 36 KPs agreed upon, diagnostic-therapeutic algorithms were developed that we believe can facilitate the implementation of programs for early identification and adequate management of perioperative anemia, adapted to the characteristics of the different institutions in our country.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 4","pages":"Pages 225-232"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139998733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Nobel Prize paradox: Nobel Prize, not a noble prize","authors":"Khaled Moustafa","doi":"10.1016/j.rceng.2024.03.001","DOIUrl":"10.1016/j.rceng.2024.03.001","url":null,"abstract":"<div><p>The Nobel Prize is one of the most sought-after awards in science and society. However, its reputation is not without complexities, including constraints on laureates and biases in nominations. Navigating the delicate balance between recognition and the tangible impacts of awarded contributions should offer insight into the Prize's significance beyond mere prestige and monetary value. While other awards may boast higher financial rewards, they often lack the same level of prestige. The inclusion of public figures as laureates and the extensive media coverage surrounding the Nobel Prize may further elevate its perceived importance, though this may hide a more nuanced reality. Additionally, the positive associations linked to the name “Nobel” resembling the adjective “noble” can enhance the award's prestige. This subtle connection to “nobility” adds a layer of honor and distinction to the Prize, contributing to its perceived significance and prestige. Moreover, the overrepresentation of Nobel laureates from specific countries prompts scrutiny over the fulfillment of Nobel's testament, which prioritizes contributions to global well-being. This discrepancy raises questions about the inclusivity and global impact of the Prize.</p></div>","PeriodicalId":94354,"journal":{"name":"Revista clinica espanola","volume":"224 4","pages":"Pages 233-236"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140061689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}