Comparative performance of vulvovaginal swab sampling versus endocervical sampling for the detection of Chlamydia, Gonorrhea, Mycoplasma genitalium, and Trichomoniasis: a cross-sectional study in Spain

Revista clinica espanola Pub Date : 2024-06-01 DOI:10.1016/j.rceng.2024.04.015

M. Linares , P. Galicia , A. Rojas , A. Miguel-Benito , J. Cuadros-González , J.M. Ramos-Rincón

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Abstract

Introduction

The global increase in sexual transmitted infections (STI) makes it necessary to seek public health strategies that facilitate rapid and minimally invasive diagnosis. The objective was to evaluate the concordance between vaginal and endocervical samples for STI diagnosis.

Materials and methods

A retrospective cross-sectional study was carried out on vaginal and endocervical samples from women attended in our reference area with symptoms suggestive of vulvovaginitis or for STI screening during the study period.

Results

A total of 130 paired samples were analyzed; fifty-seven and 59 samples were positive for vaginal and endocervical specimens (Kappa index of 0.969 (Standard error = 0.022). The sensitivity of the vaginal samples was 96.5% (IC95%: 87.2–99.4), with a specificity of 100% (IC95%: 93.0–100).

Discussion

The introduction of STI screening in vaginal samples in our environment can facilitate rapid and effective diagnosis and allow early treatment of STI. Additionally, it facilitates sample collection and diagnosis in the community setting, essential for optimal screening.

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外阴拭子取样与宫颈内膜取样在检测衣原体、淋病、生殖器支原体和滴虫病方面的性能比较：西班牙的一项横断面研究

导言：随着全球性传播感染（STI）的增加，有必要寻求有利于快速和微创诊断的公共卫生策略。本研究旨在评估阴道和宫颈内膜样本在性传播感染诊断中的一致性：在研究期间，我们对参考区内出现外阴阴道炎症状或接受性传播感染筛查的妇女的阴道和宫颈内膜样本进行了回顾性横断面研究：共分析了 130 份配对样本；阴道和宫颈内膜样本中分别有 57 份和 59 份呈阳性（Kappa 指数为 0.969（标准误差 = 0.022））。阴道样本的敏感性为 96.5%（IC95%：87.2-99.4），特异性为 100%（IC95%：93.0-100）：讨论：在我们的环境中，对阴道样本进行性传播感染筛查可促进快速有效的诊断，并使性传播感染得到早期治疗。此外，它还有助于在社区环境中进行样本采集和诊断，这对优化筛查至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Revista clinica espanola

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