Cardiovascular Journal of Africa最新文献

{"title":"From the Editor's Desk.","authors":"P J Commerford","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 5","pages":"263"},"PeriodicalIF":0.7,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141174733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of early postoperative results in patients with and without diabetes with low ejection fraction and normal serum creatinine values who underwent coronary artery bypass operation.","authors":"Cihan Yücel,&nbsp;İlhan Özgöl","doi":"10.5830/CVJA-2023-052","DOIUrl":"https://doi.org/10.5830/CVJA-2023-052","url":null,"abstract":"<p><strong>Background: </strong>Low left ventricular ejection fraction and renal insufficiency are factors that increase the risk of coronary artery bypass graft surgery in patients with diabetes mellitus. The aim of this study was to group patients with low left ventricular ejection fraction undergoing coronary artery bypass graft surgery according to the presence or absence of diabetes mellitus and to evaluate postoperative changes in serum creatinine levels and postoperative outcomes.</p><p><strong>Methods: </strong>A total of 93 patients undergoing isolated coronary artery bypass grafting were included in this single-centre, retrospective, cohort study. Patients with a pre-operative low left ventricular ejection fraction of less than 35% were included in the study. Patients were divided into diabetic and non-diabetic groups and intra- and intergroup values were compared. Pre-operative, and postoperative days 2 and 5 serum creatinine levels of the patients were measured and compared.</p><p><strong>Results: </strong>Of the 93 patients included in the study, 60 were in the diabetic group (group 1) and 33 were in the non-diabetic group (group 2). Postoperative 2- and 5-day creatinine levels were significantly higher in group 1 than in group 2 (<i>p</i> = 0.033 and <i>p</i> = 0.005, respectively). Postoperative 2- and 5-day creatinine levels were significantly higher than pre-operative creatinine levels in group 1 (<i>p</i> = 0.008 and <i>p</i> = 0.001, respectively). The intensive care unit stay was significantly longer in the diabetes mellitus group than in the group without diabetes mellitus (<i>p</i> = 0.031).</p><p><strong>Conclusion: </strong>Following coronary artery bypass graft surgery in patients with low left ventricular ejection fraction, which is already a risk factor, creatinine levels were found to have increased in the diabetes mellitus group.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-5"},"PeriodicalIF":0.7,"publicationDate":"2023-10-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coronary artery bypass grafting in a patient with situs inversus totalis.","authors":"Taha Okan,&nbsp;Caner Topaloglu,&nbsp;Orhan Kucuk,&nbsp;Selen Bayraktaroglu,&nbsp;Naim Ceylan","doi":"10.5830/CVJA-2023-051","DOIUrl":"https://doi.org/10.5830/CVJA-2023-051","url":null,"abstract":"<p><p>Situs inversus totalis (SIT) describes a complete mirror image of the visceral organs in the thoracic and abdominal cavities. Dextrocardia, in combination with SIT, is a rare congenital anomaly with a frequency of 1:10 000, and coronary heart disease may occur with a similar frequency and manifestation as in the general population. Coronary computed tomography (CT) angiography is useful for accurately assessing the coronary artery origin and position for preprocedural planning of difficult coronary artery catheterisation in SIT. In this case, invasive coronary angiography (ICA) was performed from the same angle but on the opposite side compared to standard angiography. With the use of volume-rendered three-dimensional and curved reformatted images reconstructed from coronary CT angiography, the advancement of guidewires and catheters during ICA as well as the planning of surgical procedures can be performed more safely.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-4"},"PeriodicalIF":0.7,"publicationDate":"2023-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation between maternally expressed gene 3 expression and heart rate variability in heart failure patients with ventricular arrhythmia.","authors":"Ling Lin,&nbsp;Mei Hou,&nbsp;Ailing Yang,&nbsp;Yunfei Li,&nbsp;Rong Su,&nbsp;Li Li,&nbsp;Siyun Wu,&nbsp;Mingguo Zhang","doi":"10.5830/CVJA-2023-044","DOIUrl":"https://doi.org/10.5830/CVJA-2023-044","url":null,"abstract":"<p><strong>Aim: </strong>The aim of the study was to analyse the correlation between maternally expressed gene 3 (MEG3) expression and heart rate variability (HRV) in heart failure patients with ventricular arrhythmia (VA).</p><p><strong>Methods: </strong>A total of 130 heart failure patients, treated from July 2018 to March 2021, were prospectively selected and divided into a non-VA group (<i>n</i> = 85) and a VA group (<i>n</i> = 45) according to the presence or absence of VA. The correlations of serum MEG3 expression and HRV with cardiac function indicators were investigated by Pearson correlation analysis. Receiver operating characteristic (ROC) curves were plotted to assess the predictive value of MEG3, HRV and their combination for the occurrence of heart failure complicated with VA.</p><p><strong>Results: </strong>The VA group had a higher left atrial diameter (LAD) and left ventricular end-diastolic diameter (LVEDD) but lower left ventricular ejection fraction (LVEF) and ratio of mitral early diastolic peak velocity (E) to late peak atrial filling velocity (A) (E/A) than the non-VA group (<i>p</i> < 0.05). The serum MEG3 expression was negatively correlated with: standard deviation of the average RR intervals calculated over five-minute segments in the 24-hour record (SDANN), SDANN index, standard deviation of normal-to-normal RR interval (SDNN) index, percentage of differences between adjacent normal RR intervals exceeding 50 ms (PNN50), root mean square of successive difference (RMSSD), low frequency (LF), high frequency (HF), very low frequency (VLF), LVEF and E/A (<i>r</i> < 0, <i>p</i> < 0.05). The serum MEG3 expression was positively correlated with LAD and LVEDD (<i>r</i> > 0, <i>p</i> < 0.05). The areas under the ROC curves of MEG3, SDANN, SDANN index, SDNN index, PNN50, RMSSD, LF, HF, VLF and their combination for the prediction of the occurrence of heart failure complicated with VA were 0.812, 0.731, 0.737, 0.689, 0.860, 0.783, 0.791, 0.856, 0.769 and 0.966, respectively.</p><p><strong>Conclusion: </strong>MEG3 combined with HRV can effectively predict the occurrence of heart failure complicated with VA.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-5"},"PeriodicalIF":0.7,"publicationDate":"2023-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel U-shaped relationship between serum klotho and abdominal aortic calcification in the general population.","authors":"Na Wei,&nbsp;Zuolei Shi,&nbsp;Yan Gong","doi":"10.5830/CVJA-2023-048","DOIUrl":"https://doi.org/10.5830/CVJA-2023-048","url":null,"abstract":"<p><strong>Background: </strong>Abdominal aortic calcification (AAC) is considered an independent predictor of cardiovascular morbidity and mortality. Klotho, an anti-aging gene, has cardiovascular protective effects. At present, the association between klotho and AAC in the general population is uncertain. We investigated the relationship between serum soluble α-klotho (SSKL) and AAC in 2 327 participants from the National Health and Nutrition Examination Survey.</p><p><strong>Methods: </strong>To estimate the association between log-transformed SSKL (lnSSKL) and AAC, multivariate logistic regression analyses were conducted. Stratified analyses were performed to evaluated the potential modifiers. Smoothed curve fitting and generalised additive models were also performed.</p><p><strong>Results: </strong>We found lnSSKL correlated negatively with AAC after adjusting for other confounders. The relationship of lnSSKL with AAC was a U-shaped curve (inflection point: 7.01 pg/ml). On subgroup analyses, stratified by age and smoking habit, the negative correlation of lnSSKL with AAC remained in men and in the population who smoked.</p><p><strong>Conclusion: </strong>Our study revealed a negative relationship between lnSSKL and AAC in the general population. This relationship showed a U-shaped curve and was influenced by age and smoking habit.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2023-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420949","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Echocardiographic multiparameter assessment for patients with heart failure with preserved ejection fraction and atrial fibrillation.","authors":"Lingling Qin,&nbsp;Junhua Yang,&nbsp;Fenglan Xu","doi":"10.5830/CVJA-2023-047","DOIUrl":"https://doi.org/10.5830/CVJA-2023-047","url":null,"abstract":"<p><p>We aimed to assess the echocardiographic parameters of cardiac structure and function in patients with heart failure with preserved ejection fraction (HFpEF) and atrial fibrillation (AF). Thirty-seven HFpEF patients with AF were selected, while 38 patients with simple HFpEF in the same period were selected as controls. Three-dimensional speckle-tracking echocardiography was performed on both groups and the parameters were compared. The early diastolic longitudinal peak strain rates [early diastolic longitudinal strain rate (LSR_E), early diastolic circumferential strain rate (CSR_E), early diastolic radial strain rate (RSR_E) and early diastolic rotational strain rate (RotR_E)], late diastolic longitudinal peak strain rates (LSR_A, CSR_A, RSR_A and RotR_A) and untwisting parameters [untwisting rate during isovolumic relaxation time (UTR_IVR) and early peak untwisting rate (UTR_E)] were all negatively correlated with the ratio of early diastolic transmitral velocity to early diastolic mitral annular velocity ( E/E') (<i>p</i> < 0.01). The cardiac event-free survival rate of the simple HFpEF group (92.11%) was significantly higher than that of the HFpEF + AF group (81.08%) (<i>p</i> < 0.0001). UTR_IVR had a more significant correlation with E/E' ratio than the other indicators and could serve as a sensitive indicator for evaluating the diastolic function of patients with HFpEF + AF.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between adiponectin and copeptin levels with long-term cardiovascular mortality in ST-segment elevation myocardial infarction after percutaneous coronary intervention.","authors":"Ayça Türer Cabbar,&nbsp;Ersin Yıldırım,&nbsp;Özge Güzelburç Çalbayram,&nbsp;Mustafa A Şimşek,&nbsp;Servet Altay,&nbsp;Kazım S Özcan,&nbsp;M Muzaffer Değertekin","doi":"10.5830/CVJA-2023-046","DOIUrl":"https://doi.org/10.5830/CVJA-2023-046","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to determine adiponectin and copeptin levels that might be prognostic for cardiovascular mortality (CvsM) in ST-segment elevation myocardial infarction (STEMI) patients who had percutaneous coronary intervention (PCI).</p><p><strong>Methods: </strong>Patients who underwent PCI between November 2010 and April 2011 were enrolled and followed for more than eight years. The baseline, demographic and angiographic findings, in-hospital follow up, laboratory results including adiponectin and copeptin levels, and echocardiographic data of the patients were evaluated.</p><p><strong>Results: </strong>There were 78 males and 20 females. The CvsM rate was 26.66% at 112 months of follow up. Some factors were significantly related to CvsM and adiponectin level was an independent predictor of mortality. A cut-off value of ≥ 8 950 ng/ml for adiponectin and ≥ 7.41 ng/ml for copeptin was related to a 3.01- and 2.83-times higher CvsM risk, respectively.</p><p><strong>Conclusion: </strong>Adiponectin level was a predictor for CvsM. Higher levels of adiponectin and copeptin could predict a higher risk of CvsM in STEMI patients.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-8"},"PeriodicalIF":0.7,"publicationDate":"2023-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420855","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between serum α-klotho level and the prevalence of heart failure in the general population.","authors":"Weimin Luo,&nbsp;Na Wei,&nbsp;Zhaoling Sun,&nbsp;Yan Gong","doi":"10.5830/CVJA-2023-042","DOIUrl":"https://doi.org/10.5830/CVJA-2023-042","url":null,"abstract":"<p><strong>Background: </strong>Heart failure is a major cause of global morbidity and mortality. Studies in laboratory animals have shown the direct protective effects of α-klotho on the cardiovascular system although it has limited expression in the heart. The association between α-klotho and cardiovascular disease is still controversial in different clinical studies. We designed a cross-sectional study in order to investigate the association between serum α-klotho level and the prevalence of heart failure in the American general population.</p><p><strong>Methods: </strong>The data were obtained from the National Health and Nutrition Examination Survey (NHANES), which included 11 271 participants aged 40-80 years. Serum α-klotho level was examined by enzyme-linked immunosorbent assay and divided into four quartiles for further analysis. Heart failure status was obtained from self-reported questionnaires. To estimate the association between α-klotho level and prevalence of heart failure, multivariate logistic regression analyses were conducted. Interaction and stratified analyses were performed to evaluate the potential modifiers.</p><p><strong>Results: </strong>After adjusting for multiple covariates, a per-standard deviation increase in serum α-klotho level was associated with a decrease in prevalence of heart failure [odds ratio (OR): 0.76, 95% confidence interval (CI): 0.68-0.85). The ORs for participants in quartiles 2 to 4 were 0.77 (95% CI: 0.58-1.01), 0.70 (95% CI: 0.52-0.93) and 0.71 (95% CI: 0.53-0.95), respectively, compared with those in quartile 1. Stratified analysis revealed significant gender and racial differences.</p><p><strong>Conclusion: </strong>We revealed an independent association between serum α-klotho level and the prevalence of heart failure in the American general population. The association was not always consistent and varied according to gender and race.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Six months of resistance training improves heart rate variability in the elderly.","authors":"Matteus Dinis Oliveira,&nbsp;Perciliany Martins de Souza,&nbsp;Aparecida Patricia Guimarães,&nbsp;Lenice Kappes Becker,&nbsp;Daniel Barbosa Coelho,&nbsp;Emerson Cruz de Oliveira","doi":"10.5830/CVJA-2023-050","DOIUrl":"https://doi.org/10.5830/CVJA-2023-050","url":null,"abstract":"<p><p>Heart rate variability is a non-invasive method of assessing global health through the analysis of the autonomous centralnervous system, including both the sympathetic and parasympathetic systems. The aim of this study was to evaluate the effect of resistance training on heart rate variability at rest in elderly individuals undergoing six months of resistance training with progressive loads. Training reduced the body fat percentage of the volunteers (pre: 39.39 ± 7.21 vs post: 34.97 ± 6.40%; <i>p</i> = 0.0069). There was also a significant reduction in the low-frequency index (pre: 69621.50 ± 9817.28 vs post: 54210.50 ± 14903.94; <i>p</i> = 0.0322) and a significant increase in the high-frequency index (pre: 30308.00 ± 9857.86 vs post: 45627.10 ± 14838.80; <i>p</i> = 0.0326). We concluded that sixmonths of resistance training with progressive loads were beneficial for heart rate variability and reduced the body fat percentage in the elderly.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":"34 ","pages":"1-6"},"PeriodicalIF":0.7,"publicationDate":"2023-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71420856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Application of computed tomographic angiography and echocardiography in predicting left atrial appendage thrombosis in patients with non-valvular atrial fibrillation.","authors":"Xiaodan Wu, Fan Sun, Shoucheng Ma, Zhichen Wang, Shenghai Xu","doi":"10.5830/CVJA-2022-052","DOIUrl":"10.5830/CVJA-2022-052","url":null,"abstract":"<p><strong>Aim: </strong>We aimed to explore the application of computed tomographic angiography (CTA) and echocardiography in predicting left atrial appendage (LAA) thrombosis in patients with non-valvular atrial fibrillation.</p><p><strong>Methods: </strong>The clinical data of 164 atrial fibrillation patients receiving cardiac CTA and real-time three-dimensional transoesophageal echocardiography (RT-3D-TEE) were retrospectively analysed. The patients were divided into group A (anticoagulant treatment group, <i>n</i> = 112) and group B (selective anticoagulant treatment group, <i>n</i> = 52) according to the CHA₂DS₂-VASc score, which scored for the presence or absence of congestive heart failure, hypertension, age ≥ 75 years, diabetes mellitus, stroke/transient ischaemic attack, vascular disease, age 65-74 years and gender (female). The CHA₂DS₂-VASc score was used to predict risk of thromboembolism from atrial fibrillation. The correlations of CHA₂DS₂-VASc score with CTA-based LAA classification and RT-3D-TEE measurement parameters were explored using Spearman's analysis. Receiver operating characteristic (ROC) curves were plotted to explore the predictive value of CTA and RT-3D-TEE for LAA thrombus.</p><p><strong>Results: </strong>There were significant differences in age, disease course, hypertension, diabetes mellitus, coronary heart disease, heart failure, stroke/transient ischaemic attack/thromboembolism, vascular disease, B-type natriuretic peptide and serum uric acid levels, CHA₂DS₂-VASc score, LAA classification, left ventricular ejection fraction (LVEF), left atrial diameter (LAD), maximum diameter of LAA orifice, minimum diameter of LAA orifice and LAA length (<i>p</i> < 0.05). CHA₂DS₂- VASc score was positively correlated with cauliflower LAA, LAD, maximum diameter of LAA orifice, minimum diameter of LAA orifice and LAA length, and negatively correlated with LVEF (<i>p</i> < 0.001). ROC curve analysis indicated that CTA, RT-3D-TEE and CHA₂DS₂-VASc score had similar predictive values for risk of LAA thrombosis in atrial fibrillation patients, with the areas under the curve being 0.778, 0.814 and 0.792, respectively.</p><p><strong>Conclusions: </strong>Both CTA and RT-3D-TEE had high predictive values for LAA thrombosis in atrial fibrillation patients.</p>","PeriodicalId":9434,"journal":{"name":"Cardiovascular Journal of Africa","volume":" ","pages":"231-236"},"PeriodicalIF":0.7,"publicationDate":"2023-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10870313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40466590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}