经皮冠状动脉介入治疗后ST段抬高型心肌梗死患者脂联素和copeptin水平与长期心血管死亡率的关系。

IF 0.7 4区医学 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS

Cardiovascular Journal of Africa Pub Date : 2023-10-04 DOI:10.5830/CVJA-2023-046

Ayça Türer Cabbar, Ersin Yıldırım, Özge Güzelburç Çalbayram, Mustafa A Şimşek, Servet Altay, Kazım S Özcan, M Muzaffer Değertekin

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引用次数: 0

摘要

目的：本研究的目的是确定在接受经皮冠状动脉介入治疗（PCI）的ST段抬高型心肌梗死（STEMI）患者中，脂联素和copeptin水平可能是心血管死亡率（CvsM）的预后。对患者的基线、人口学和血管造影结果、住院随访、实验室结果（包括脂联素和copeptin水平）以及超声心动图数据进行了评估。结果：男78例，女20例。随访112个月时，CvsM发生率为26.66%。一些因素与CvsM显著相关，脂联素水平是死亡率的独立预测因素。脂联素的临界值≥8 950 ng/ml和copeptin的临界值≤7.41 ng/ml分别与CvsM风险高3.01倍和2.83倍有关。结论：脂联素水平是CvsM的预测指标。高水平的脂联素和copeptin可以预测STEMI患者患CvsM的风险更高。

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Relationship between adiponectin and copeptin levels with long-term cardiovascular mortality in ST-segment elevation myocardial infarction after percutaneous coronary intervention.

Objective: The aim of this study was to determine adiponectin and copeptin levels that might be prognostic for cardiovascular mortality (CvsM) in ST-segment elevation myocardial infarction (STEMI) patients who had percutaneous coronary intervention (PCI).

Methods: Patients who underwent PCI between November 2010 and April 2011 were enrolled and followed for more than eight years. The baseline, demographic and angiographic findings, in-hospital follow up, laboratory results including adiponectin and copeptin levels, and echocardiographic data of the patients were evaluated.

Results: There were 78 males and 20 females. The CvsM rate was 26.66% at 112 months of follow up. Some factors were significantly related to CvsM and adiponectin level was an independent predictor of mortality. A cut-off value of ≥ 8 950 ng/ml for adiponectin and ≥ 7.41 ng/ml for copeptin was related to a 3.01- and 2.83-times higher CvsM risk, respectively.

Conclusion: Adiponectin level was a predictor for CvsM. Higher levels of adiponectin and copeptin could predict a higher risk of CvsM in STEMI patients.

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来源期刊

Cardiovascular Journal of Africa CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

4-8 weeks

期刊介绍： The Cardiovascular Journal of Africa (CVJA) is an international peer-reviewed journal that keeps cardiologists up to date with advances in the diagnosis and treatment of cardiovascular disease. Topics covered include coronary disease, electrophysiology, valve disease, imaging techniques, congenital heart disease (fetal, paediatric and adult), heart failure, surgery, and basic science.