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Pulmonary Lymphatics History, Anatomy, and Pathophysiology: Emerging Knowledge and a Look to the Future. 肺淋巴管的历史、解剖和病理生理学：新兴知识与未来展望。
Lymphology Pub Date : 2024-01-01
B Kelly, S Daley
{"title":"Pulmonary Lymphatics History, Anatomy, and Pathophysiology: Emerging Knowledge and a Look to the Future.","authors":"B Kelly, S Daley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Central lymphatic disorders of the lung have not received intense investigation. Lymphatic system physiology is presented in the context of historical developments and basic lung lymphatic anatomy is reviewed followed by emerging characteristics of primary and secondary pathophysiological disturbances of lymphatic involvement in a number of pulmonary diseases including Gorham-Stout disease, pulmonary edema and infections and inflammatory conditions including lymphangioleiomyomatosis (LAM). The future includes potential molecular targeting of lymphangiogenesis or lymphatic vessels for interventional occlusion. This article is an amalgamation of presentations at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease and as part of a Special Symposium on the Lymphatic system of the Heart and Lung in Health and Disease at the 26th International Congress of Lymphology meeting held in Barcelona, Spain, September 2017, which has been updated to 2024.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Liver Lymphatic Anatomy and Its Role in Systemic Health and Disease. 肝脏淋巴解剖及其在全身健康和疾病中的作用。
Lymphology Pub Date : 2024-01-01
C Smith
{"title":"Liver Lymphatic Anatomy and Its Role in Systemic Health and Disease.","authors":"C Smith","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphatic anatomy of the abdomen is reviewed with focus on hepatic and mesenteric vessels in normal and pathologic conditions. Anatomy and pathophysiology is highlight using both specialized fluoroscopy and T2 Dynamic Contrast MR lymphangiography (DCMRL). Plastic bronchitis, chylothorax, protein losing enteropathy, and both cirrhosis and ascites due to hepatic lymphatics are highlighted. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Imaging and Interventional Management of Lymphatic Disorders. 淋巴系统疾病的成像和介入治疗。
Lymphology Pub Date : 2024-01-01
E Pinto
{"title":"Imaging and Interventional Management of Lymphatic Disorders.","authors":"E Pinto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphatic flow disorders are reviewed, and a classification based on magnetic resonance lymphography findings outlined. Examples of successful interventional management based on this classification are provided. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lymphatic Imaging and Intervention in Central Lymphatic Disorders. 中枢淋巴系统疾病的淋巴成像和干预。
Lymphology Pub Date : 2024-01-01
Y Dori
{"title":"Lymphatic Imaging and Intervention in Central Lymphatic Disorders.","authors":"Y Dori","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Advances in lymphatic imaging for both diagnosis and intervention are reviewed, and specific examples given for protein-losing enteropathy, multi compartment lymphatic failure, congestive heart failure. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Returning the Central Lymphatic System to the Center of Lymphology. 让中央淋巴系统回归淋巴学的中心。
Lymphology Pub Date : 2024-01-01
M H Witte
{"title":"Returning the Central Lymphatic System to the Center of Lymphology.","authors":"M H Witte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>After the introduction of conventional oil contrast lymphography and the founding of the discipline of lymphology, great impetus was given to investigating central lymphatic system and its disorders along with lymphatic involvement and specifically lymphostasis in common diseases of major organs such as the liver (cirrhosis) and heart (heart failure). Gradually interest shifted to more peripheral disorders such as limb lymphedema and its treatment by physical and surgical measures. At the same time, basic lymphology turned to the study of isolate-ed ex vivo and in vitro, including lymphatic endothelial models and more recently, molecular lymphology focusing on lymphatic growth and modulating factors, genes and proteins under-lying primary lymphedema, and more potential biomarkers of lymphatic disease have gained prominence. However, it has been advances in lymphatic imaging, namely lymphoscintigraphy with SPECT-CT high resolution 3-D pictures and magnetic resonance imaging (contrast and non-contrast) of the peripheral and particularly central lymphatic system by more invasive means combined with endovascular interventional techniques to treat complex and life-threatening lymphatic disorders that has returned the central lymphatic system to the center of lymphology, where the journey began.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Physiology and Functional Pathology of the Lymphatic System with Implications for the Fontan Patient. 淋巴系统的生理学和功能病理学及其对丰坦患者的影响。
Lymphology Pub Date : 2024-01-01
V Hjortdal
{"title":"Physiology and Functional Pathology of the Lymphatic System with Implications for the Fontan Patient.","authors":"V Hjortdal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Contractile function of the collecting lymphatic vessels depend on smooth muscle cells, one-way valves, surrounding tissues, and regulation by the autonomic nervous system. The potentially deleterious effects of the Fontan procedure and elevated central venous pressure on lymphatic function leading to life-threatening complications are described. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Looking Backward and Looking Forward: Revisiting "Clinical Usefulness of Thoracic Duct Cannulation". 回顾过去，展望未来：重新审视 "胸导管置管的临床实用性"。
Lymphology Pub Date : 2024-01-01
M H Witte
{"title":"Looking Backward and Looking Forward: Revisiting \"Clinical Usefulness of Thoracic Duct Cannulation\".","authors":"M H Witte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Over the past decade, there has been a resurgence of interest in the thoracic duct and central lymphatic system and its disorders, stimulated by advances in interventional magnetic resonance imaging techniques and urgent challenges in the clinical management of lymphatic malformations and lymphatic complications from congenital heart disease. The following chapter reprinted here written shortly after the formal founding of the discipline of lymphology and the International Society of Lymphology, describes early efforts, and also suggests future directions now being revisited and others yet to be explored (1).</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Brain Lymphatics: Rediscovery and New Insights into Lymphatic Involvement in Diseases of Human Brains. 脑淋巴管：脑淋巴管：人脑疾病中淋巴管参与的再发现和新见解》（Rediscovery and New Insights into Lymphatic Involvement in Diseases of Human Brains）。
Lymphology Pub Date : 2024-01-01
M J Bartlett, R P Erickson, E B Hutchinson, R S Witte, M H Witte
{"title":"Brain Lymphatics: Rediscovery and New Insights into Lymphatic Involvement in Diseases of Human Brains.","authors":"M J Bartlett, R P Erickson, E B Hutchinson, R S Witte, M H Witte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The brain's lymphatic system is comprised of a glymphatic-meningeal-cervical lymphatic vessel pathway. The study of its mechanism and pathophysiology in neurodegenerative disease has been one of the most exciting topics in basic and translational neuroscience of the last decade. However, while there has been some debate about when the meningeal lymphatics were discovered, it cannot be denied that studies in preclinical models and humans in this century represent a monumental step forward in our understanding of how the brain removes metabolic waste, the role this system plays in neurodegenerative disease, and, most importantly, its potential as a novel therapeutic target. This is a summary of the history, functional anatomy, and role of the brain's lymphatics in neurodegenerative disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Memoriam: Hugo Partsch: Phlebolylmphologist Extraordinaire 1938-2023. 悼念：Hugo Partsch：1938-2023年杰出的卟啉卟啉学家。
Lymphology Pub Date : 2023-01-01
M H Witte
{"title":"In Memoriam: Hugo Partsch: Phlebolylmphologist Extraordinaire 1938-2023.","authors":"M H Witte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We are sad to report the passing but will commemorate here the life and accomplishments of Hugo Partsch, MD, formerly Professor of Dermatology at the University of Vienna and Head of the Dermatological De-partment at the Wilhelminen Hospital in Vienna.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141428647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In Memoriam: Dr. Alejandro Latorre Parra: Professor, and Passionate Lymphologist (1956-2023). 悼念亚历杭德罗-拉托雷-帕拉博士：教授，热情洋溢的淋巴学家（1956-2023 年）。
Lymphology Pub Date : 2023-01-01
M H Witte
{"title":"In Memoriam: Dr. Alejandro Latorre Parra: Professor, and Passionate Lymphologist (1956-2023).","authors":"M H Witte","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We are sad to report the passing but will commemorate here the life and accomplishments of Alejandro Latorre Parra, MD, formerly Professor of the Medicine program at the Autonomous University of Bucaramanga - UNAB Faculty of Health Sciences and Director of the Escuela Colombiana de Linfologia.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142116794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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