{"title":"Feasibility and Potential Benefits of Moderate Intensity Cycling in People Living with Lower Limb Lymphedema: A Pilot Randomized Controlled Trial.","authors":"C Jonsson, K Johansson, M Bjurberg, C Brogardh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this pilot randomized con-trolled trial (RCT) was to assess the feasibility of a moderate intensity cycling intervention in persons with lower limb lymphedema (LLL) and to explore its potential benefits. Thirty-three participants were included for an 8-week intervention of home-based exercise and randomized to an intervention group (IG) with cycling 3-5 times a week, 30-60 minutes, or to a control group (CG). Feasibility was assessed by recruitment and retention rates, adherence to training protocol, and adverse events. Potential benefits were physical fitness (submaximal bicycle ergometer test), volume, local tissue water, impedance of extracellular fluid, lymphedema-related disability (Lymph-ICF-LL) and health-related quality of life (Lymphedema Quality of Life Inventory). Assessments were performed at baseline and after 8 weeks. Non-parametric analyses were used. Twenty-seven participants (IG=16; CG=11), median age 63 years and time with LLL 9 years, completed the trial. Retention to group allocation was 82%, training protocol adherence was 81% and only one adverse event occurred. Significant between-group improvement was found for lymphedema-related disability favoring the IG. Within-group improvements regarding physical fitness, local tissue water and health-related quality of life were found in the IG, but not in the CG. In conclusion, this study shows that moderate intensity cycling is feasible with potential benefits in functioning and health-related quality of life for persons with chronic LLL.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"58 1","pages":"11-22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144061651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pyomyositis of the Piriformis Muscle Secondary to Cellulitis Complicating Lymphedema.","authors":"M Tsujita, Y Suzuki, T Kato, K Kishi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A woman in her 70s with a 20-year history of postoperative edema and repeated cellulitis after surgery and chemotherapy for ovarian cancer presented with pain, redness, and swelling in her left lower leg. She was admitted with dehydration, disorientation, and elevated inflammation. After antibiotic treatment, redness of the lower extremities gradually improved. However, the patient complained of severe back pain after 10 days of treatment. Computed tomography (CT) revealed an abscess of the right pisiform muscle and patient was diagnosed with pyomyositis of the piriformis muscle. On hospital day 18, CT-guided percutaneous drainage of the abscess was performed. At the 6-month follow-up, there was no recurrence of the abscess. It is difficult to diagnose pyomyositis of the piriformis muscle via physical examination. This extremely rare case involves pyomyositis of the piriformis muscle as a result of cellulitis due to lymphedema. If antibiotic treatment for cellulitis in a patient with lymphedema is unsuccessful and severe pain persists, early imaging diagnosis should be considered.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"58 1","pages":"29-33"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144049595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Maccio, M Quattro, L Biava, C Palmero, T Galli, S Caruso
{"title":"Lymphangiosarcoma, a Rare Complication of Lymphostasis: An Observational Study on the Role of the Physiotherapist in Early Recognition and Medical Referral.","authors":"A Maccio, M Quattro, L Biava, C Palmero, T Galli, S Caruso","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphangiosarcoma is a rare, malignant angiosarcoma that primarily develops in limbs with chronic lymphedema and presents with dermal lesions. Due to a 5-year survival rate of 22.4%, early detection and treatment are critical for improving prognosis. This study assessed physiotherapists' skills in recognizing suspicious dermal lesions in lymphedema patients with a focus on lymphangiosarcoma. An 11-question online survey was created using Google Forms that included academic training, practical experience, frequency of lymphatic treatments, ability to recognize suspicious dermal lesions, referral frequency to specialists, and opinions on specific training needs. The study was conducted from 9 February to 30 March, 2024 and it targeted Italian physiotherapists who manage patients with lymphedema. Responses were received from 170 physiotherapists. Only 12.9% had university education on dermal lesions in lymphedema patients, while 70.6% had postgraduate training. Additionally, 57.6% felt unable to recognize lymphangiosarcoma. Postgraduate education was correlated with the ability to recognize the pathology (p=0.047). Clinical experience and frequency of lymphatic treatments was associated with recognition and reporting of suspected cases (p<0.05). Findings suggest the need for increased awareness and specialized training among physiotherapists to improve early detection and treatment of lymphangiosarcoma in lymphedema patients. Enhanced postgraduate education and clinical experience may lead to better patient outcomes.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"58 1","pages":"34-41"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Shiraishi, M Narushima, C H Banda, Y Moriwaki, K Kojima, K Yamagata, C Kondo, K Mitsui, K Hashimoto, K Danno, K Hosomi, R Ishiura, M Kurita, I Koshima
{"title":"Treatment Strategies and Effectiveness in Lymphatic Malformations: A 10-Year Retrospective Study.","authors":"M Shiraishi, M Narushima, C H Banda, Y Moriwaki, K Kojima, K Yamagata, C Kondo, K Mitsui, K Hashimoto, K Danno, K Hosomi, R Ishiura, M Kurita, I Koshima","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recurrence is a major challenge in treatment of lymphatic malformations (LMs) world-wide. The objectives of the current study were to investigate risk factors associated with LM recurrence and to compare effectiveness of surgical and endovascular treatments. A multi-center 10-year retrospective chart review was conducted on all consecutive patients treated for LMs from 2009 to 2019. Data collected included post-treatment size, symptoms, and recurrence. Stepwise multiple regression analysis was used to identify risk factors and to compare treatment modalities. A total of 13 patients with 20 treatment cases were included. No significant difference was observed in size reduction and symptom alleviation between the treatment groups. Resection showed the highest recurrence rate of 36.4% (p=0.04) and lymphaticovenular anastomosis (LVA) presented excel-lent results in post-treatment size, symptoms, and recurrence despite lack of statistical significance. Microcystic type of LMs was identified as an independent risk factor for recurrence. Both surgery and sclerotherapy are effective in improving size and symptoms of LMs. This data will help physicians and patients choose the optimal treatment and potentially predict progression.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"58 1","pages":"1-10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pressurized Contrast Injection in a Lymphocele Can Reveal an Embolizable Lymphopseudoaneurysm in Postsurgical Chylous Ascites.","authors":"Q Verhalleman, V Hartman, G Roeyen, T Jardinet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This report describes the technique of lymphopseudoaneurysm (LPA) detection by pressurized contrast injection into a lymphocele, followed by image-guided embolization. A 37-year-old man with pancreatic neuro-endocrine tumor, portal cavernoma, and liver metastasis underwent pancreaticoduodenectomy, right hepatectomy, lymphadenectomy, and left portal vein reconstruction. Postoperative course was complicated by refractory chylous ascites. Computed Tomography (CT) revealed a centrally located lymphocele in the abdominal cavity. Direct puncture of the lymphocele, followed by pressurized contrast injection revealed a tubular connection to a smaller retroperitoneal collection near the surgical site, which was considered to be the culprit LPA. After catheter directed embolization of this LPA with N-butyl-cyanoacrylate glue, chylous ascites ceased and abdominal drainage catheters were removed 12 days later.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"58 1","pages":"23-28"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Format Correction: The Re-Discovery of Dural (Meningeal) Lymphatics: Amnesia or Ambition?","authors":"R P Erickson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There were multiple formatting issues identified with the article: \"The Re-Discovery of Dural (Meningeal) Lymphatics: Amnesia or Ambition?\" By R.P. Erickson (Lymphology 56 (2023) 125-130; https://doi.org/10.2458/lymph.6179). These have been corrected and the article has been updated. The journal regrets the original errors in formatting.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"58 1","pages":"42"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144045730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary Lymphatics History, Anatomy, and Pathophysiology: Emerging Knowledge and a Look to the Future.","authors":"B Kelly, S Daley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Central lymphatic disorders of the lung have not received intense investigation. Lymphatic system physiology is presented in the context of historical developments and basic lung lymphatic anatomy is reviewed followed by emerging characteristics of primary and secondary pathophysiological disturbances of lymphatic involvement in a number of pulmonary diseases including Gorham-Stout disease, pulmonary edema and infections and inflammatory conditions including lymphangioleiomyomatosis (LAM). The future includes potential molecular targeting of lymphangiogenesis or lymphatic vessels for interventional occlusion. This article is an amalgamation of presentations at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease and as part of a Special Symposium on the Lymphatic system of the Heart and Lung in Health and Disease at the 26th International Congress of Lymphology meeting held in Barcelona, Spain, September 2017, which has been updated to 2024.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 1","pages":"19-26"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Liver Lymphatic Anatomy and Its Role in Systemic Health and Disease.","authors":"C Smith","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphatic anatomy of the abdomen is reviewed with focus on hepatic and mesenteric vessels in normal and pathologic conditions. Anatomy and pathophysiology is highlight using both specialized fluoroscopy and T2 Dynamic Contrast MR lymphangiography (DCMRL). Plastic bronchitis, chylothorax, protein losing enteropathy, and both cirrhosis and ascites due to hepatic lymphatics are highlighted. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 1","pages":"12-15"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Imaging and Interventional Management of Lymphatic Disorders.","authors":"E Pinto","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Lymphatic flow disorders are reviewed, and a classification based on magnetic resonance lymphography findings outlined. Examples of successful interventional management based on this classification are provided. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 1","pages":"8-11"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Lymphatic Imaging and Intervention in Central Lymphatic Disorders.","authors":"Y Dori","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Advances in lymphatic imaging for both diagnosis and intervention are reviewed, and specific examples given for protein-losing enteropathy, multi compartment lymphatic failure, congestive heart failure. Presented at the 2023 ISL International Congress of Lymphology, Genoa, Italy in a special symposium on central and regional lymphatic system in health and disease.</p>","PeriodicalId":94343,"journal":{"name":"Lymphology","volume":"57 1","pages":"4-7"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142485055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}