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miR-135b: an emerging player in cardio-cerebrovascular diseases miR-135b：心脑血管疾病的新兴参与者
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.100997
Yingchun Shao, Jiazhen Xu, Wujun Chen, Minglu Hao, Xinlin Liu, Renshuai Zhang, Yanhong Wang, Yinying Dong
{"title":"miR-135b: an emerging player in cardio-cerebrovascular diseases","authors":"Yingchun Shao, Jiazhen Xu, Wujun Chen, Minglu Hao, Xinlin Liu, Renshuai Zhang, Yanhong Wang, Yinying Dong","doi":"10.1016/j.jpha.2024.100997","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100997","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"22 S3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141023016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor microenvironment-responsive hyperbranched polymers for controlled drug delivery 用于控制药物输送的肿瘤微环境响应超支化聚合物
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.101003
Yuqiong Guo, Xinni He, Gareth R. Williams, Yue Zhou, Xinying Liao, Ziyi Xiao, Cuiyun Yu, Yang Liu
{"title":"Tumor microenvironment-responsive hyperbranched polymers for controlled drug delivery","authors":"Yuqiong Guo, Xinni He, Gareth R. Williams, Yue Zhou, Xinying Liao, Ziyi Xiao, Cuiyun Yu, Yang Liu","doi":"10.1016/j.jpha.2024.101003","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.101003","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"40 4","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer 临床和口服兼容配方制造的 DDX5 (p68) 靶向分子胶 FL118 产品对人类癌症具有低毒性和高效性
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.101001
Xiang Ling, Wenjie Wu, Li Yan, Leslie I Curtin, Melanie M. Farrauto, Sandra Sexton, Anmbreen Jamroze, Changjun Yu, Christos Fountzilas, Dean G. Tang, Fengzhi Li
{"title":"Clinically and orally compatible formulation-manufactured DDX5 (p68)-targeting molecular glue FL118 products exhibit low toxicity but high efficacy against human cancer","authors":"Xiang Ling, Wenjie Wu, Li Yan, Leslie I Curtin, Melanie M. Farrauto, Sandra Sexton, Anmbreen Jamroze, Changjun Yu, Christos Fountzilas, Dean G. Tang, Fengzhi Li","doi":"10.1016/j.jpha.2024.101001","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.101001","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"261 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141039494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Machine learning-driven optimization of mRNA-lipid nanoparticle vaccine quality with XGBoost/Bayesian method and ensemble model approaches 利用 XGBoost/Bayesian 方法和集合模型方法，以机器学习为驱动优化 mRNA 脂质纳米粒子疫苗质量
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.100996
Ravi Maharjan, Ki Hyun Kim, Kyeong Lee, Hyo-Kyung Han, Seong Hoon Jeong
{"title":"Machine learning-driven optimization of mRNA-lipid nanoparticle vaccine quality with XGBoost/Bayesian method and ensemble model approaches","authors":"Ravi Maharjan, Ki Hyun Kim, Kyeong Lee, Hyo-Kyung Han, Seong Hoon Jeong","doi":"10.1016/j.jpha.2024.100996","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100996","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"10 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Software-aided efficient identification of the components of compound formulae and their metabolites in rats by UHPLC/IM-QTOF-MS and an in-house high-definition MS2 library: Sishen Formula as a case 利用 UHPLC/IM-QTOF-MS 和内部高清 MS2 库，在软件辅助下高效鉴定大鼠体内的复方成分及其代谢物：以四神方为例
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.100994
Lili Hong, Wei Wang, Shiyu Wang, Wan-di Hu, Yuyang Sha, Xiao-yan Xu, Xiaoying Wang, Kefeng Li, Hongda Wang, Xiumei Gao, Dean Guo, W. Yang
{"title":"Software-aided efficient identification of the components of compound formulae and their metabolites in rats by UHPLC/IM-QTOF-MS and an in-house high-definition MS2 library: Sishen Formula as a case","authors":"Lili Hong, Wei Wang, Shiyu Wang, Wan-di Hu, Yuyang Sha, Xiao-yan Xu, Xiaoying Wang, Kefeng Li, Hongda Wang, Xiumei Gao, Dean Guo, W. Yang","doi":"10.1016/j.jpha.2024.100994","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100994","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"25 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141047564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cirsium japonicum mitigates allergic nasal inflammation by regulating NRF2-mediated mucin production: systematic transcriptome and molecular docking analyses 日本长春花通过调节 NRF2 介导的粘蛋白生成减轻过敏性鼻炎：系统转录组和分子对接分析
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.101000
Bo-Jeong Pyun, Su-Jin Baek, Kyuhyung Jo, Ik Soo Lee, Musun Park, Hye Jin Kim, Joo Young Lee, Susanna Choi, Yun Hee Kim, Taesoo Kim
{"title":"Cirsium japonicum mitigates allergic nasal inflammation by regulating NRF2-mediated mucin production: systematic transcriptome and molecular docking analyses","authors":"Bo-Jeong Pyun, Su-Jin Baek, Kyuhyung Jo, Ik Soo Lee, Musun Park, Hye Jin Kim, Joo Young Lee, Susanna Choi, Yun Hee Kim, Taesoo Kim","doi":"10.1016/j.jpha.2024.101000","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.101000","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"19 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141143713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multidimensional screening of Astragalus membranaceus small molecules to mitigate carbon ion radiation-induced bystander effects 多维筛选黄芪小分子以减轻碳离子辐射诱导的旁观者效应
Journal of pharmaceutical analysis Pub Date : 2024-05-01 DOI: 10.1016/j.jpha.2024.100999
Liying Zhang, Yi-ming Zhang, Yangyang Li, Qiyang Li, Shangzu Zhang, Zhiming Miao, Jinpeng He, Ting Zhou, Gengqiang Yang, Xin Wang, Jufang Wang, Yongqi Liu
{"title":"Multidimensional screening of Astragalus membranaceus small molecules to mitigate carbon ion radiation-induced bystander effects","authors":"Liying Zhang, Yi-ming Zhang, Yangyang Li, Qiyang Li, Shangzu Zhang, Zhiming Miao, Jinpeng He, Ting Zhou, Gengqiang Yang, Xin Wang, Jufang Wang, Yongqi Liu","doi":"10.1016/j.jpha.2024.100999","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100999","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"7 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141052430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway 通过安罗替尼介导的细胞外基质和RhoA/ROCK信号通路调节提高抗肿瘤药物的肿瘤靶向性
Journal of pharmaceutical analysis Pub Date : 2024-04-01 DOI: 10.1016/j.jpha.2024.100984
Xuedan Han, Jialei Liu, Yidong Zhang, Eric Tse, Qiyi Yu, Yu Lu, Yi Ma, Lufeng Zheng
{"title":"Increasing the tumour targeting of antitumour drugs through anlotinib-mediated modulation of the extracellular matrix and the RhoA/ROCK signalling pathway","authors":"Xuedan Han, Jialei Liu, Yidong Zhang, Eric Tse, Qiyi Yu, Yu Lu, Yi Ma, Lufeng Zheng","doi":"10.1016/j.jpha.2024.100984","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100984","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"693 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140776957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats 氢溴酸卤夫酮纳米复合物在佐剂诱导的大鼠关节炎中促进巨噬细胞再极化和类风湿性关节炎成纤维细胞样滑膜细胞凋亡的双靶向作用
Journal of pharmaceutical analysis Pub Date : 2024-04-01 DOI: 10.1016/j.jpha.2024.100981
Junping Zhu, Ye Lin, Gejing Li, Yini He, Zhaoli Su, Yuanyuan Tang, Ye Zhang, Qian Xu, Zhongliu Yao, Hua Zhou, Bin Liu, Xiong Cai
{"title":"Dual-targeted halofuginone hydrobromide nanocomplexes for promotion of macrophage repolarization and apoptosis of rheumatoid arthritis fibroblast-like synoviocytes in adjuvant-induced arthritis in rats","authors":"Junping Zhu, Ye Lin, Gejing Li, Yini He, Zhaoli Su, Yuanyuan Tang, Ye Zhang, Qian Xu, Zhongliu Yao, Hua Zhou, Bin Liu, Xiong Cai","doi":"10.1016/j.jpha.2024.100981","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100981","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"44 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140756057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Targeting NTCP for liver disease treatment: A promising strategy 靶向NTCP治疗肝病：前景广阔的战略
Journal of pharmaceutical analysis Pub Date : 2024-04-01 DOI: 10.1016/j.jpha.2024.100979
Xin Tan, Yu Xiang, Jianyou Shi, Lu Chen, Dongke Yu
{"title":"Targeting NTCP for liver disease treatment: A promising strategy","authors":"Xin Tan, Yu Xiang, Jianyou Shi, Lu Chen, Dongke Yu","doi":"10.1016/j.jpha.2024.100979","DOIUrl":"https://doi.org/10.1016/j.jpha.2024.100979","url":null,"abstract":"","PeriodicalId":94338,"journal":{"name":"Journal of pharmaceutical analysis","volume":"964 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140761350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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