Critical reviews in biomedical engineering最新文献

Mathematical Modeling of Oxygen Diffusion from Capillary to Tissues during Hypoxia through Multiple Points Using Fractional Balance Equations with Memory. 利用带记忆的分数平衡方程建立缺氧时氧气通过多点从毛细血管向组织扩散的数学模型。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2024053461

Vineet Srivastava, Dharmendra Tripathi, P K Srivastava, Sireetorn Kuharat, O Anwar Bég

{"title":"Mathematical Modeling of Oxygen Diffusion from Capillary to Tissues during Hypoxia through Multiple Points Using Fractional Balance Equations with Memory.","authors":"Vineet Srivastava, Dharmendra Tripathi, P K Srivastava, Sireetorn Kuharat, O Anwar Bég","doi":"10.1615/CritRevBiomedEng.2024053461","DOIUrl":"https://doi.org/10.1615/CritRevBiomedEng.2024053461","url":null,"abstract":"The diffusion of oxygen through capillary to surrounding tissues through multiple points along the length has been addressed in many clinical studies, largely motivated by disorders including hypoxia. However relatively few analytical or numerical studies have been communicated. In this paper, as a compliment to physiological investigations, a novel mathematical model is developed which incorporates the multiple point diffusion of oxygen from different locations in the capillary to tissues, in the form of a fractional dynamical system of equations using the concept of system of balance equations with memory. Stability analysis of the model has been conducted using the well known Routh-Hurwitz stability criterion. Comprehensive analytical solutions for the differntial equation problem in the new proposed model are obtained using Henkel transformations. Both spatial and temporal variation of concentration of oxygen is visualized graphically for different control parameters. Close correlation with simpler models is achieved. Diffusion is shown to arise from different points of the capillary in decreasing order along the length of the capillary i.e. for the different values of z. The concentration magnitudes at low capillary length far exceed those further along the capillary. Furthermore with progrssive distance along the capillary, the radial distance of diffusion decreases, such that oxygen diffuses only effectively in very close proximity to tissues. The simulations provide a useful benchmark for more generalized mass diffusion computations with commercial finite element and finite volume software including ANSYS FLUENT.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cilia and Nodal Flow in Asymmetry: An Engineering Perspective. 不对称中的纤毛和节点流：工程学视角。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2024051678

Madisyn Messmore, Alain J Kassab, Ray O Prather, David A Castillo Arceo, William DeCampli

{"title":"Cilia and Nodal Flow in Asymmetry: An Engineering Perspective.","authors":"Madisyn Messmore, Alain J Kassab, Ray O Prather, David A Castillo Arceo, William DeCampli","doi":"10.1615/CritRevBiomedEng.2024051678","DOIUrl":"10.1615/CritRevBiomedEng.2024051678","url":null,"abstract":"Over the past several years, cilia in the primitive node have become recognized more and more for their contribution to development, and more specifically, for their role in axis determination. Although many of the mechanisms behind their influence remain undocumented, it is known that their presence and motion in the primitive node of developing embryos is the determinant of the left-right axis. Studies on cilial mechanics and nodal fluid dynamics have provided clues as to how this asymmetry mechanism works, and more importantly, have shown that direct manipulation of the flow field in the node can directly influence physiology. Although relatively uncommon, cilial disorders have been shown to have a variety of impacts on individuals from chronic respiratory infections to infertility, as well as situs inversus which is linked to congenital heart disease. After first providing background information pertinent to understanding nodal flow and information on why this discussion is important, this paper aims to give a review of the history of nodal cilia investigations, an overview of cilia mechanics and nodal flow dynamics, as well as a review of research studies current and past that sought to understand the mechanisms behind nodal cilia's involvement in symmetry-breaking pathways through a biomedical engineering perspective. This discussion has the additional intention to compile interdisciplinary knowledge on asymmetry and development such that it may encourage more collaborative efforts between the sciences on this topic, as well as provide insight on potential paths forward in the field.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Critical Review on Detection of Foodborne Pathogens Using Electrochemical Biosensors. 关于使用电化学生物传感器检测食源性病原体的评论。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2023049469

Avinash V Police Patil, Ping-Feng Yang, Chiou-Ying Yang, M S Gaur, Ching-Chou Wu

{"title":"A Critical Review on Detection of Foodborne Pathogens Using Electrochemical Biosensors.","authors":"Avinash V Police Patil, Ping-Feng Yang, Chiou-Ying Yang, M S Gaur, Ching-Chou Wu","doi":"10.1615/CritRevBiomedEng.2023049469","DOIUrl":"10.1615/CritRevBiomedEng.2023049469","url":null,"abstract":"An outbreak of foodborne pathogens would cause severe consequences. Detecting and diagnosing foodborne diseases is crucial for food safety, and it is increasingly important to develop fast, sensitive, and cost-effective methods for detecting foodborne pathogens. In contrast to traditional methods, such as medium-based culture, nucleic acid amplification test, and enzyme-linked immunosorbent assay, electrochemical biosensors possess the advantages of simplicity, rapidity, high sensitivity, miniaturization, and low cost, making them ideal for developing pathogen-sensing devices. The biorecognition layer, consisting of recognition elements, such as aptamers, antibodies and bacteriophages, and other biomolecules or polymers, is the most critical component to determine the selectivity, specificity, reproducibility, and lifetime of a biosensor when detecting pathogens in a biosample. Furthermore, nanomaterials have been frequently used to improve electrochemical biosensors for sensitively detecting foodborne pathogens due to their high conductivity, surface-to-volume ratio, and electrocatalytic activity. In this review, we survey the characteristics of biorecognition elements and nanomaterials in constructing electrochemical biosensors applicable for detecting foodborne pathogens during the past five years. As well as the challenges and opportunities of electrochemical biosensors in the application of foodborne pathogen detection are discussed.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Channel-Specific and Spatial Residual Attention Network for Medical Image Denoising. 用于医学图像去噪的特定通道和空间残留注意力网络

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2024053351

Jianhua Hu, Woqing Huang, Haoxian Zhang, Zhanjiang Yuan, Xiangfei Feng, Weimei Wu

{"title":"Channel-Specific and Spatial Residual Attention Network for Medical Image Denoising.","authors":"Jianhua Hu, Woqing Huang, Haoxian Zhang, Zhanjiang Yuan, Xiangfei Feng, Weimei Wu","doi":"10.1615/CritRevBiomedEng.2024053351","DOIUrl":"https://doi.org/10.1615/CritRevBiomedEng.2024053351","url":null,"abstract":"Medical image quality is crucial for physicians to ensure accurate diagnosis and therapeutic strategies. However, due to the interference of noise, there are often various types of noise and artifacts in medical images. This not only damages the visual clarity of images, but also reduces the accuracy of information extraction. Considering that the edges of medical images are rich in high-frequency information, to enhance the quality of medical images, a dual attention mechanism, the channel-specific and spatial residual attention network (CSRAN) in the U-Net framework is proposed. The CSRAN seamlessly integrates the U-Net architecture with channel-wise and spatial feature attention (CSAR) modules, as well as low-frequency channel attention modules. Combined with the two modules, the ability of medical image processing to extract high-frequency features is improved, thereby significantly improving the edge effects and clarity of reconstructed images. This model can present better performance in capturing high-frequency information and spatial structures in medical image denoising and super-resolution reconstruction tasks. It cannot only enhance the ability to extract high-frequency features and strengthen its nonlinear representation capability, but also endow strong edge detection capabilities of the model. The experimental results further prove the superiority of CSRAN in medical image denoising and super-resolution reconstruction tasks.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring the Potential Mechanisms of Zhu-Ye-Qing Wine in Preventing Cardiovascular and Cerebrovascular Diseases Based on Network Pharmacology. 基于网络药理学探索竹叶青酒预防心脑血管疾病的潜在机制

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2024053713

Yujie Bai, Xin Zhang, Fang Wang, Ying Li, Shiwei Guo, Jingjing Feng, Chenshuai Xu, Huan Gao, Jianfeng Guo

{"title":"Exploring the Potential Mechanisms of Zhu-Ye-Qing Wine in Preventing Cardiovascular and Cerebrovascular Diseases Based on Network Pharmacology.","authors":"Yujie Bai, Xin Zhang, Fang Wang, Ying Li, Shiwei Guo, Jingjing Feng, Chenshuai Xu, Huan Gao, Jianfeng Guo","doi":"10.1615/CritRevBiomedEng.2024053713","DOIUrl":"https://doi.org/10.1615/CritRevBiomedEng.2024053713","url":null,"abstract":"Cardiovascular and cerebrovascular disease (CCVD) is a complex disease with a long latency period, and the most effective diagnosis and treatment methods are risk assessment and preventive interventions before onset. According to traditional Chinese medicine (TCM), Zhu-Ye-Qing wine (ZYQW) has the effect of invigorating blood and removing blood stasis. However, whether ZYQW can improve the progression of CCVD has not been reported. This study aims to explore the possible mechanism of ZYQW on CCVD through network pharmacology, and finally 249 potential targets of ZYQW and 2080 potential targets of CCVD are obtained. The key targets mainly include MAPK3, TP53, RELA, MAPK1 and AKT1. The main KEGG pathways include TNF signaling pathway, lipid and atherosclerosis pathway signaling pathway. The components in ZYQW are identified by ultra-performance liquid chromatography-mass spectrometry (UHPLC-CQE-CQE-MS/MS). Through network pharmacology, molecular docking and molecular dynamics simulation, the potential key components and prevention mechanisms of ZYQW in the prevention of CCVD are determined. ZYQW may be an effective and safe health food for the prevention of CCVD, providing guidance and basis for the further development of medicinal foods.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141877142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relevant Biomechanical Variables in Skateboarding: A Literature Review. 滑板运动中的相关生物力学变量：文献综述。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2024052903

Juan Baus, Ethan Nguyen, John R Harry, James Yang

{"title":"Relevant Biomechanical Variables in Skateboarding: A Literature Review.","authors":"Juan Baus, Ethan Nguyen, John R Harry, James Yang","doi":"10.1615/CritRevBiomedEng.2024052903","DOIUrl":"10.1615/CritRevBiomedEng.2024052903","url":null,"abstract":"Skateboarding, once regarded primarily as a means of transportation and entertainment for youth, has become a recognized professional sport, gaining global popularity. With its recent inclusion in the Olympics, a growing imperative exists to comprehensively understand biomechanics explaining skateboarding performance. This literature review seeks to consolidate knowledge within this domain, focusing on experimental and modeling studies about skateboard riding and tricks. The criteria for study selection encompassed content relevance and publication year, spanning from the last two decades and extending further back to 1980 following cross-referencing of seminal works. Peer-reviewed journal articles, conference proceedings, and books were considered, with comprehensive searches conducted on electronic databases, including SCOPUS, PubMed, Scielo, and Taylor & Francis. Comprehending the biomechanical facets of skateboarding is essential in promoting its use and ensuring safety among all practitioners. Insights into factors such as body kinetics, kinematics, and muscle activation represent a foundational step toward understanding the nuances of this sport with implications for both clinical and biomechanical research. Modern data collection systems such as inertial measurement units (IMU) and electromyography (EMG) offer unprecedented insights into human performance during skateboarding, such as joint range of motion, coordination, and muscle activation, whether in casual riding or executing complex tricks and maneuvers. Developing robust modeling approaches also holds promise for enhancing skateboarding training and performance. Crucially, these models can serve as the initial framework for understanding injury mechanisms and implementing strategies to improve performance and mitigate injury risks.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141082037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review on Retinal Blood Vessel Enhancement and Segmentation Techniques for Color Fundus Photography. 彩色眼底摄影视网膜血管增强和分割技术综述。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2023049348

Sakambhari Mahapatra, Sanjay Agrawal, Pranaba K Mishro, Rutuparna Panda, Lingraj Dora, Ram Bilas Pachori

{"title":"A Review on Retinal Blood Vessel Enhancement and Segmentation Techniques for Color Fundus Photography.","authors":"Sakambhari Mahapatra, Sanjay Agrawal, Pranaba K Mishro, Rutuparna Panda, Lingraj Dora, Ram Bilas Pachori","doi":"10.1615/CritRevBiomedEng.2023049348","DOIUrl":"10.1615/CritRevBiomedEng.2023049348","url":null,"abstract":"The retinal image is a trusted modality in biomedical image-based diagnosis of many ophthalmologic and cardiovascular diseases. Periodic examination of the retina can help in spotting these abnormalities in the early stage. However, to deal with today's large population, computerized retinal image analysis is preferred over manual inspection. The precise extraction of the retinal vessel is the first and decisive step for clinical applications. Every year, many more articles are added to the literature that describe new algorithms for the problem at hand. The majority of the review article is restricted to a fairly small number of approaches, assessment indices, and databases. In this context, a comprehensive review of different vessel extraction methods is inevitable. It includes the development of a first-hand classification of these methods. A bibliometric analysis of these articles is also presented. The benefits and drawbacks of the most commonly used techniques are summarized. The primary challenges, as well as the scope of possible changes, are discussed. In order to make a fair comparison, numerous assessment indices are considered. The findings of this survey could provide a new path for researchers for further work in this domain.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71490878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient Electrochemiluminescence Sensing in Microfluidic Biosensors: A Review. 微流控生物传感器中的高效电化学发光传感：综述。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2023049565

Clementine Juliat Louw, Pim de Haan, Elisabeth Verpoorte, Priscilla Baker

{"title":"Efficient Electrochemiluminescence Sensing in Microfluidic Biosensors: A Review.","authors":"Clementine Juliat Louw, Pim de Haan, Elisabeth Verpoorte, Priscilla Baker","doi":"10.1615/CritRevBiomedEng.2023049565","DOIUrl":"10.1615/CritRevBiomedEng.2023049565","url":null,"abstract":"Microfluidic devices are capable of handling 10-9 L to 10-18 L of fluids by incorporating tiny channels with dimensions of ten to hundreds of micrometers, and they can be fabricated using a wide range of materials including glass, silicon, polymers, paper, and cloth for tailored sensing applications. Microfluidic biosensors integrated with detection methods such as electrochemiluminescence (ECL) can be used for the diagnosis and prognosis of diseases. Coupled with ECL, these tandem devices are capable of sensing biomarkers at nanomolar to picomolar concentrations, reproducibly. Measurement at this low level of concentration makes microfluidic electrochemiluminescence (MF-ECL) devices ideal for biomarker detection in the context of early warning systems for diseases such as myocardial infarction, cancer, and others. However, the technology relies on the nature and inherent characteristics of an efficient luminophore. The luminophore typically undergoes a redox process to generate excited species which emit energy in the form of light upon relaxation to lower energy states. Therefore, in biosensor design the efficiency of the luminophore is critical. This review is focused on the integration of microfluidic devices with biosensors and using electrochemiluminescence as a detection method. We highlight the dual role of carbon quantum dots as a luminophore and co-reactant in electrochemiluminescence analysis, drawing on their unique properties that include large specific surface area, easy functionalization, and unique luminescent properties.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140208774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in Chronic Wound Management: From Conventional Treatment to Novel Therapies and Biological Dressings. 慢性伤口管理的进展：从传统治疗到新型疗法和生物敷料。

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2024053066

Anisa Andleeb, Hamza Khan, Aneeta Andleeb, Maria Khan, Muhammad Tariq

{"title":"Advances in Chronic Wound Management: From Conventional Treatment to Novel Therapies and Biological Dressings.","authors":"Anisa Andleeb, Hamza Khan, Aneeta Andleeb, Maria Khan, Muhammad Tariq","doi":"10.1615/CritRevBiomedEng.2024053066","DOIUrl":"10.1615/CritRevBiomedEng.2024053066","url":null,"abstract":"Chronic wounds can be classified as diabetic foot ulcers, pressure ulcers, or venous leg ulcers. Chronic wound management has become a threat to clinicians and constitutes a major healthcare burden. The healing process of chronic wounds requires many factors to work in concert to achieve optimal healing. Various treatment options, ranging from hypoxia to infection, have evolved considerably to address the challenges associated with chronic wound healing. The conventional and accelerating treatments for chronic wounds still represent an unmet medical need due to the complex pathophysiology of the chronic wound microenvironment. In clinical settings, traditional chronic wound care practices rely on nonspecific topical treatment, which can reduce pain and alleviate disease progression with varying levels of success but fail to completely cure the wounds. Conventional wound dressings, such as hydrocolloids, gauze, foams, and films, have also shown limited success for the treatment of chronic wounds and only act as a physical barrier and absorb wound exudates. Emerging advances in treatment approaches, including novel therapies (stem cells, microRNAs, and nanocarrier-based delivery systems) and multifunctional biological dressings, have been reported for chronic wound repair. This review summarizes the challenges offered by chronic wounds and discusses recent advancements in chronic wound treatment.","PeriodicalId":94308,"journal":{"name":"Critical reviews in biomedical engineering","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141332841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of Wavy Arteries and Veins on Hemodynamic Characteristics: A Numerical Study. 波状动脉和静脉对血液动力学特征的影响：数值研究

Critical reviews in biomedical engineering Pub Date : 2024-01-01 DOI: 10.1615/CritRevBiomedEng.2023050535

Shreyas Kotian, Nishant Jain, Nachiket Methekar, Shailesh Nikam

引用次数: 0