G. Mckee, A. Choi, C. Madill, J. Marriott, P. Kibsey, D. Hoyano
{"title":"Outbreak of invasive Streptococcus pneumoniae among an inner-city population in Victoria, British Columbia, 2016-2017.","authors":"G. Mckee, A. Choi, C. Madill, J. Marriott, P. Kibsey, D. Hoyano","doi":"10.14745/CCDR.V44I12A02","DOIUrl":"https://doi.org/10.14745/CCDR.V44I12A02","url":null,"abstract":"Background\u0000Invasive pneumococcal disease (IPD) is a significant cause of morbidity and mortality; however, outbreaks of IPD are relatively rare. Homelessness and substance use are known risk factors for IPD and have been associated with several outbreaks in Canada, despite national recommendations for routine childhood and targeted adult pneumococcal vaccination.\u0000\u0000\u0000Objectives\u0000To describe the epidemiology and public health challenges related to an outbreak of novel serotype 4 IPD in a homeless and unstably housed population in Victoria, British Columbia during the autumn and winter of 2016-2017.\u0000\u0000\u0000Results\u0000Prospective, enhanced surveillance was initiated for laboratory confirmed cases reported to public health, including variables recording housing status and substance use. Thirty-three cases of serotype 4 IPD within the Victoria area were reported to public health between August 1, 2016 and September 1, 2017. Compared with other serotypes, these cases were more likely to be middle-aged, homeless or unstably housed, and to have a recent history of substance use. A targeted pneumococcal vaccination campaign was initiated in collaboration with external community organizations; however, these initiatives were challenged by incomplete data and staffing constraints.\u0000\u0000\u0000Conclusion\u0000This report illustrates an outbreak of serotype 4 IPD among an inner-city population with multiple risk factors, including homelessness, unstable housing and substance use. Given the challenges controlling the outbreak, outreach capacity and pneumococcal vaccination coverage is needed among this marginalized population.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"4 1","pages":"317-322"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73065193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
V. Dubey, O. Ozaldin, L. Shulman, R. Stuart, J. Maclachlan, L. Bromley, A. Summers
{"title":"Investigation and management of a large community mumps outbreak among young adults in Toronto, Canada, January 2017-February 2018.","authors":"V. Dubey, O. Ozaldin, L. Shulman, R. Stuart, J. Maclachlan, L. Bromley, A. Summers","doi":"10.14745/CCDR.V44I12A01","DOIUrl":"https://doi.org/10.14745/CCDR.V44I12A01","url":null,"abstract":"Background\u0000In 2017, a mumps outbreak was identified in a cohort of 18-34 year olds in Toronto, Canada.\u0000\u0000\u0000Objective\u0000To describe a large community mumps outbreak in an urban centre from January 2017 to February 2018 among young adults.\u0000\u0000\u0000Methods\u0000A broad range of interventions were implemented in an attempt to reach the target audience; including case and contact management, vaccination clinics at schools and clinicians' offices, school exclusions, bar inspections, traditional communication strategies (including health care provider updates and posters) and newer communication strategies (including three sequential social media campaigns).\u0000\u0000\u0000Results\u0000A total of 143 cases of mumps were identified. Although cases' ages ranged from three to 72 years, most (76%) were 18-34 year olds, many of whom had frequented bars and local food establishments in downtown Toronto. 84% (n=120) of the cases were community-acquired. Only 16% (n=23) of the cases reported exposures in schools and post-secondary school institutions. Of those, 39% (n=56) of cases had an unknown vaccination history; 34% (n=49) were either not vaccinated or partially vaccinated with one dose of measles-mumps-rubella vaccine; and 27% (n=38) had received the recommended two doses of mumps vaccine. Determining vaccination status was a challenge, in part due to the lack of a registry. Vaccination was recommended when subjects were known to have had fewer than two doses of vaccine or had an unknown vaccination status. A social media campaign, emphasizing the risk of social activities if not protected from the mumps, yielded over 500,000 impressions from Facebook and Twitter messages and ads and an impressive engagement rate of between 1% and 10x%.\u0000\u0000\u0000Conclusion\u0000This was the largest mumps outbreak in Toronto in over 20 years. Among young adults, ongoing social media and traditional communication campaigns can contribute to the control of community mumps outbreaks. Encouraging vaccine uptake is desirable, but without a vaccine registry it is difficult to assess vaccination coverage among adults. Susceptible cohorts of young adults who were not adequately vaccinated pose a risk for future outbreaks. Given that almost 30% of the mumps cases were fully vaccinated with two doses of mumps-containing vaccine, even two doses may not provide complete protection.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"21 1","pages":"309-316"},"PeriodicalIF":0.0,"publicationDate":"2018-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82903068","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bringing home unwelcome souvenirs: Travel and drug-resistant bacteria.","authors":"BJ Langford, KL Schwartz","doi":"10.14745/CCDR.V44I11A02","DOIUrl":"https://doi.org/10.14745/CCDR.V44I11A02","url":null,"abstract":"Antimicrobial resistance poses a significant threat to public health globally and in Canada. Wide regional variability in antimicrobial resistance and ongoing increases in global travel present an important risk for the acquisition and transmission of drug-resistant organisms. Travel from high-income to low- and middle-income countries, particularly the Indian subcontinent, present the greatest risks for acquiring a drug-resistant Enterobacteriaceae. Risk factors for returning from travel with drug-resistant organisms include seeking medical care while abroad, travellers' diarrhea and antibiotic use. Health care professionals can play an important role in preventing harm for travellers by counselling patients on the risks of acquiring drug-resistant organisms, appropriate antibiotic prescribing for travellers' diarrhea and tailored empiric therapy for patients presenting with infection after travel.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"9 1","pages":"277-282"},"PeriodicalIF":0.0,"publicationDate":"2018-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73694602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J D Greig, I Young, S Harding, M Mascarenhas, L A Waddell
{"title":"A scoping review of Lyme disease research relevant to public health.","authors":"J D Greig, I Young, S Harding, M Mascarenhas, L A Waddell","doi":"10.14745/ccdr.v44i10a03","DOIUrl":"https://doi.org/10.14745/ccdr.v44i10a03","url":null,"abstract":"<p><p>Lyme disease (LD) is an emerging infectious disease in Canada associated with expansion of the geographic range of the tick vector <i>Ixodes scapularis</i> in eastern and central Canada. A scoping review of published research was prioritized to identify and characterize the scientific evidence concerning key aspects of LD to support public health efforts. Prior to initiation of this review, an expert advisory group was surveyed to solicit insight on priority topics and scope. A pre-tested search strategy implemented in eight databases (updated September 2016) captured relevant research. Pre-tested screening and data characterization forms were completed by two independent reviewers and descriptive analysis was conducted to identify topic areas with solid evidence and knowledge gaps. Of 19,353 records screened, 2,258 relevant articles were included in the review under the following six public health focus areas: a) surveillance/monitoring in North America (n=809); b) evaluation of diagnostic tests (n=736); c) risk factors (n=545); d) public health interventions (n=205); e) public knowledge, attitudes and/or perceptions in North America (n=202); and f) the economic burden of LD or cost-benefit of interventions (n=32). The majority of research investigated <i>Borrelia burgdorferi</i> (n=1,664), humans (n=1,154) and <i>Ixodes scapularis</i> (n=459). Sufficient research was identified for potential systematic reviews in four topic areas: a) accuracy of diagnostic tests; b) risk factors for human illness; c) efficacy of LD intervention strategies; and d) prevalence and/or incidence of LD in humans or <i>B. burgdorferi</i> sensu stricto in vertebrate reservoirs or ticks in North America. Future primary research could focus on closing knowledge gaps, such as the role of less studied vertebrate reservoirs in the transmission cycle. Results of this scoping review can be used to quickly identify and summarize relevant research pertaining to specific questions about LD or <i>B. burgdorferi</i> sensu lato in humans, vertebrate hosts or vectors, providing evidence-informed information within timelines that are conducive for public health decision-making.</p>","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"44 10","pages":"243-256"},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707479/pdf/CCDR-44-243.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manisha A. Kulkarni, R. Kryuchkov, A. Statculescu, C. Thickstun, A. Dibernardo, L. Lindsay, Benoit Talbot
{"title":"Ixodes scapularis tick distribution and infection rates in Ottawa, Ontario, 2017.","authors":"Manisha A. Kulkarni, R. Kryuchkov, A. Statculescu, C. Thickstun, A. Dibernardo, L. Lindsay, Benoit Talbot","doi":"10.14745/CCDR.V44I10A02","DOIUrl":"https://doi.org/10.14745/CCDR.V44I10A02","url":null,"abstract":"Background\u0000The incidence of Lyme disease has increased in many regions of Canada in recent years, including in Ottawa, Ontario. To date there has been limited active tick surveillance in the region.\u0000\u0000\u0000Objectives\u0000To estimate both the distribution and density of Ixodes scapularis ticks in the city of Ottawa, and the infection rates of ticks with Borrelia burgdorferi (that causes Lyme disease) and other tick-borne pathogens.\u0000\u0000\u0000Methods\u0000Between June and October 2017, tick surveillance was conducted by drag sampling at 23 sites in Ottawa municipal parks, recreational trails and forests. Blacklegged ticks were tested for B. burgdorferi, Borrelia miyamotoi and Anaplasma phagocytophilum using quantitative polymerase chain reaction protocols.\u0000\u0000\u0000Results\u0000I. scapularis ticks were found in 16 of the 23 sites (70%). Recreational trails, conservation areas/forests and the provincial park within the city of Ottawa had significantly higher tick densities than municipal parks (p<0.01). Of the 194 adult and 26 nymphal I. scapularis tested, prevalence of infection was 29.5% for B. burgdorferi, 0.45% for B. miyamotoi and 0.91% for A. phagocytophilum.\u0000\u0000\u0000Conclusion\u0000Almost 30% of I. scapularis ticks tested in suburban and rural areas of the city of Ottawa were infected with B. burgdorferi, known to cause Lyme disease. Other types of infection, known to cause anaplasmosis and tick-borne relapsing fever, were also detected, although were very rare. Conducting active tick surveillance at the local level may help to inform risk assessment and public health actions.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"1 1","pages":"237-242"},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87282514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Nelder, S. Wijayasri, C. Russell, Ko Johnson, A. Marchand-Austin, K. Cronin, S. Johnson, T. Badiani, Samir N. Patel, D. Sider
{"title":"The continued rise of Lyme disease in Ontario, Canada: 2017.","authors":"M. Nelder, S. Wijayasri, C. Russell, Ko Johnson, A. Marchand-Austin, K. Cronin, S. Johnson, T. Badiani, Samir N. Patel, D. Sider","doi":"10.14745/CCDR.V44I10A01","DOIUrl":"https://doi.org/10.14745/CCDR.V44I10A01","url":null,"abstract":"Background\u0000Lyme disease is an infection caused by the spirochete Borrelia burgdorferi and, in most of North America, is transmitted by the blacklegged tick Ixodes scapularis. Climate change has contributed to the expansion of the geographic range of blacklegged ticks in Ontario, increasing the risk of Lyme disease for Ontarians.\u0000\u0000\u0000Objective\u0000To identify the number of cases and incidence rates, as well as the geographic, seasonal and demographic distribution of Lyme disease cases reported in Ontario in 2017, with comparisons to historical trends.\u0000\u0000\u0000Methods\u0000Data for confirmed and probable Lyme disease cases with episode dates from January 1, 2012, through December 31, 2017, were extracted from the integrated Public Health Information System (iPHIS). Data included public health unit (PHU) of residence, episode date, age and sex. Population data from Statistics Canada were used to calculate provincial and PHU-specific incidence rates per 100,000 population. The number of cases reported in 2017 by PHU of residence, month of occurrence, age and sex was compared to the 5-year averages for the period 2012-2016.\u0000\u0000\u0000Results\u0000There were 959 probable and confirmed cases of Lyme disease reported in Ontario in 2017. This was three times higher than the 5-year (2012-2016) average of 313. The provincial incidence rate for 2017 was 6.7 cases per 100,000 population, although this varied markedly by PHU. The highest incidence rates were found in Leeds-Grenville and Lanark District (128.8 cases per 100,000), Kingston-Frontenac, Lennox and Addington (87.2 cases per 100,000), Hastings and Prince Edward Counties (28.6 cases per 100,000), Ottawa (18.1 cases per 100,000) and Eastern Ontario (13.5 cases per 100,000). Cases occurred mostly from June through September, were most common among males, and those aged 5-14 and 50-69 years.\u0000\u0000\u0000Conclusion\u0000In 2017, Lyme disease incidence showed a marked increase in Ontario, especially in the eastern part of the province. If current weather and climate trends continue, blacklegged ticks carrying tick-borne pathogens, such as those causing Lyme disease, will continue to spread into suitable habitat. Monitoring the extent of this geographic spread will inform future clinical and public health actions to detect and mitigate the impact of Lyme disease in Ontario.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"21 1","pages":"231-236"},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89228677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Luna, Marsha Taylor, E. Galanis, R. Asplin, J. Huffman, Darlene Wagner, L. Hoang, A. Paccagnella, Susan Shelton, S. Ladd-Wilson, S. Seelman, B. Whitney, E. Elliot, Robin Atkinson, K. Marshall, C. Basler
{"title":"Outbreak of Salmonella Chailey infections linked to precut coconut pieces - United States and Canada, 2017†.","authors":"Sarah Luna, Marsha Taylor, E. Galanis, R. Asplin, J. Huffman, Darlene Wagner, L. Hoang, A. Paccagnella, Susan Shelton, S. Ladd-Wilson, S. Seelman, B. Whitney, E. Elliot, Robin Atkinson, K. Marshall, C. Basler","doi":"10.14745/ccdr.v44i10a05","DOIUrl":"https://doi.org/10.14745/ccdr.v44i10a05","url":null,"abstract":"Foodborne salmonellosis causes an estimated one million illnesses and 400 deaths annually in the United States (US). During March-May 2017, an outbreak of 19 cases of Salmonella Chailey associated with precut coconut pieces from a single grocery store chain occurred in the United States and Canada. The chain voluntarily recalled precut coconut pieces. This was the first time that coconut has been associated with a Salmonella outbreak in the United States or Canada. In recent years, salmonellosis outbreaks have been caused by foods not typically associated with Salmonella. Raw coconut should now be considered in investigations of Salmonella outbreaks among fresh food consumers.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"66 1","pages":"264-266"},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83172634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Results of a population screening intervention for tuberculosis in a Nunavik village, Quebec, 2015-2016.","authors":"R Dion, M Brisson, J F Proulx, H Zoungrana","doi":"10.14745/ccdr.v44i10a04","DOIUrl":"https://doi.org/10.14745/ccdr.v44i10a04","url":null,"abstract":"<p><strong>Background: </strong>A small village in Nunavik, Quebec experienced a tuberculosis (TB) outbreak in 2012-2013 and then a resurgence in 2015-2016. Cases were still occurring, despite the fact that contact tracing had already been conducted on one quarter of the population. A decision was taken to conduct large-scale screening of the population for TB.</p><p><strong>Objective: </strong>To describe the results of a population-based TB screening intervention designed to identify individuals with latent TB infection (LTBI) or active TB requiring treatment.</p><p><strong>Methodology: </strong>The history of TB infection (either active TB or LTBI, defined as a positive tuberculin skin test result of at least five mm induration) and treatment (considered adequate if at least 80% of prescribed doses were taken) were determined. Those who were two years of age and older and had not been included in contact tracing after June 1, 2015 were included for TB screening (n=1,026 eligible individuals). Screening included a nurse assessment, tuberculin skin test (TST) for those with previous negative TST or of unknown status and chest X-ray for the others.</p><p><strong>Results: </strong>Of the eligible individuals in the affected village, 1,004 (98%) participated in the screening. Of these, 30% had a history of previous TB infection. A TST screening was administered to 71% of the participants, 10% of whom had positive results. Assessments were performed on 425 participants and 385 underwent a chest X-ray. Fifty-two cases of previously diagnosed active TB and three cases of new active TB were documented. In addition, there were 247 individuals with LTBI who had been previously identified (191 were found to have had adequate LTBI treatment, 56 were found to have had inadequate LTBI treatment) and 69 were identified with <i>de novo</i> LTBI. In addition, 633 participants were found to have no TB infection. There were 125 participants who were referred for LTBI treatment. Follow-up information was available for 120 and 85 (71%) of these completed the treatment.</p><p><strong>Conclusion: </strong>Within this northern village, which had persistent TB transmission despite classic control measures, population-based screening had a high degree of coverage and was an effective way to detect additional cases of individuals with active TB and those with LTBI.</p>","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"44 10","pages":"257-263"},"PeriodicalIF":0.0,"publicationDate":"2018-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6707481/pdf/CCDR-44-257.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41224680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interim Canadian Recommendations for the use of fractional dose of yellow fever vaccine during a vaccine shortage: Now in effect.","authors":"","doi":"10.14745/ccdr.v43i02a05","DOIUrl":"https://doi.org/10.14745/ccdr.v43i02a05","url":null,"abstract":"","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"87 1","pages":"59"},"PeriodicalIF":0.0,"publicationDate":"2017-02-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81237901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"What can public health do to address inequities in infectious disease?","authors":"B. Moloughney","doi":"10.14745/CCDR.V42IS1A03","DOIUrl":"https://doi.org/10.14745/CCDR.V42IS1A03","url":null,"abstract":"Background\u0000The recognition of the importance of social conditions informed early public health responses to infectious disease epidemics. By influencing exposure, vulnerability, and access to health services, social determinants of health (SDOH) continue to cause inequalities in infectious disease distribution. Such preventable and unjust inequalities are considered to be inequities.\u0000\u0000\u0000Analysis\u0000A number of challenges and barriers exist to more widespread public health action that addresses SDOH and inequities, including a lack of clarity on what public health should or could do. The National Collaborating Centre for Determinants of Health (NCCDH) has identified four primary roles for public health action on SDOH and inequities. This paper describes these roles and includes examples of their application to infectious diseases. The critical contribution that organizations make in providing the leadership and support for programs and staff to pursue action on SDOH and inequities is also highlighted.\u0000\u0000\u0000Conclusion\u0000While the challenge is large and complex, approaches such as the NCCDH roles for public health action provide a menu of options to facilitate the analysis and action to address SDOH and inequities in infectious diseases.","PeriodicalId":94304,"journal":{"name":"Canada communicable disease report = Releve des maladies transmissibles au Canada","volume":"7 1","pages":"S114-S117"},"PeriodicalIF":0.0,"publicationDate":"2016-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91270649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}