David Rekhtman, Michaela Asher, Cindy Song, Amit Iyengar, Marisa Cevasco, Katsuhide Maeda, Constantine D Mavroudis
{"title":"Prolonged Impella 5.5 Support in a Pediatric Patient With Genetic Cardiomyopathy.","authors":"David Rekhtman, Michaela Asher, Cindy Song, Amit Iyengar, Marisa Cevasco, Katsuhide Maeda, Constantine D Mavroudis","doi":"10.1177/21501351251347948","DOIUrl":"10.1177/21501351251347948","url":null,"abstract":"<p><p>Temporary mechanical circulatory support (tMCS) has been utilized as a bridge to heart transplantation with increasing duration of support. We describe the clinical course of a 14-year-old patient, with TNNT2 and KCNQ1 mutations, requiring Impella 5.5 support for 76 days. We discuss the patient's underlying genetic etiology, potential complications of prolonged tMCS, and the importance of multidisciplinary support. To our knowledge, this is the first published case in which a patient has this specific combination of genetic mutations and the longest published support duration of an Impella 5.5 in a pediatric patient.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"861-863"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pheng Hian Tan, Ahmad Nazrin Datuk Ja'apar, Ahmad Sallehuddin
{"title":"Outcome of the Arterial Switch Operation After One Month of Age in Infants With Transposition of the Great Arteries and Intact Ventricular Septum.","authors":"Pheng Hian Tan, Ahmad Nazrin Datuk Ja'apar, Ahmad Sallehuddin","doi":"10.1177/21501351251347950","DOIUrl":"10.1177/21501351251347950","url":null,"abstract":"<p><p><b>Background:</b> The arterial switch operation (ASO) is the preferred surgical treatment for transposition of the great arteries with intact ventricular septum (TGA/IVS). Delays beyond the first month of life may lead to left ventricular deconditioning. This study evaluated the perioperative outcomes of the neonatal ASO within the first month versus later in life in a middle-income country where late presentations are common, aiming to assess the safety of the ASO beyond early intervention. <b>Method:</b> This retrospective study included 295 TGA/IVS patients who underwent the ASO from January 2010 to December 2023. We excluded those with other significant cardiac anomalies or deconditioned left ventricle (LV). Preoperatively, we evaluated the left ventricular ejection fraction and the posterior LV wall thickness to ascertain the adequacy of the LV. Study outcomes included in-hospital mortality, postoperative chest reexploration, extracorporeal membrane oxygenation use, and the duration of ventilation and hospitalization. <b>Results:</b> One hundred and fifty of 295 patients (51%) had the ASO within 30 days of life (early group) whereas 145 patients (49%) had the ASO beyond 30 days of life (late group). The mean age was 20.3 ± 5.7 days for the early group and 80.0 ± 60.0 days for the late group (<i>P</i> < .001). The late group had significantly lower in-hospital mortality (4.8% vs 14.0%, <i>P</i> = .007) and a lower incidence of chest reexploration (8.3% vs 17.3%, <i>P</i> = .020), with odds ratio of 0.312 and 0.430, respectively. <b>Conclusion:</b> Our findings indicate that the ASO performed after 30 days of life for those with a preserved LV is associated with satisfactory perioperative outcomes, underscoring the importance of carefully selecting patients who present late for the ASO.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"729-733"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144546752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ariya Chau, Shiraz A Maskatia, Basma Albuliwi, Elisabeth Martin, Kathleen R Ryan
{"title":"Favorable Vessel Patency Following Carotid Artery Reconstruction During Extracorporeal Membrane Oxygenation Decannulation in Children With Congenital Heart Disease.","authors":"Ariya Chau, Shiraz A Maskatia, Basma Albuliwi, Elisabeth Martin, Kathleen R Ryan","doi":"10.1177/21501351251338830","DOIUrl":"10.1177/21501351251338830","url":null,"abstract":"<p><p>BackgroundCarotid artery ligation has been a common practice after extracorporeal membrane oxygenation (ECMO) decannulation due to the risks of embolization, cerebral infarction, aneurysm, and stenosis over time. Carotid artery reconstruction (CAR) after ECMO decannulation is increasingly used, though studies report variable stenosis rates. Data on CAR in children with heart disease, who may require carotid artery patency for future surgery or repeat ECMO, are lacking.ObjectiveTo evaluate carotid artery patency and the incidence of cerebral infarction in pediatric cardiac patients after CAR and ECMO decannulation.MethodsA retrospective review of children (0-21 years of age) who required venoarterial extracorporeal membrane oxygenation (VA-ECMO) via neck cannulation in the cardiovascular intensive care unit at a quaternary children's hospital (2015-2022) was conducted. Children who underwent CAR and survived to discharge were included.ResultsFifty-three children (ages 2 days to 21 years, median, 2 years of age) met the study criteria. Carotid artery imaging was performed in 25 children (47%), with 84% (21/25) showing unobstructed arteries. Imaging follow-up ranged from two days to four years, with a median of three months. Of 33 children who had post-ECMO head imaging, 11 showed new cerebral infarcts, with 4 of those infarcts diagnosed following transition to ventricular assist device (VAD). Given the variability of timing and modality of head imaging and the significant proportion of patients on a VAD, we are unable to determine the true incidence of new infarcts following CAR.ConclusionCarotid artery reconstruction after VA-ECMO decannulation in children with congenital heart disease shows early favorable vessel patency, but the long-term neurological benefits compared with ligation remain unclear. Further prospective studies are needed to evaluate long-term patency and neurological outcomes.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"810-816"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144129932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manoj Kumar Daga, Nitish Kumar, Subhendu Mandal, Gaur Hari Das, Pravir Kumar Das, Anurag Agarwal, Madhurima Ghosh
{"title":"Off-Pump Coronary Artery Bypass Grafting for Congenital Left Main Coronary Artery Stenosis in a Six-Month-Old Infant: A Novel Approach.","authors":"Manoj Kumar Daga, Nitish Kumar, Subhendu Mandal, Gaur Hari Das, Pravir Kumar Das, Anurag Agarwal, Madhurima Ghosh","doi":"10.1177/21501351251330841","DOIUrl":"10.1177/21501351251330841","url":null,"abstract":"<p><p>We report a case of congenital left main coronary artery stenosis surgically treated at our center in a six-month-old patient using an off-pump coronary artery bypass grafting (CABG) approach. The infant presented with respiratory distress, feeding difficulties, and diaphoresis and was diagnosed with dilated cardiomyopathy with severe left ventricular dysfunction. Diagnostic imaging with computed tomography (CT) angiography and coronary angiography identified severe stenosis (>90%) of the left main coronary artery with normal right-sided coronary anatomy. A left internal thoracic artery to left anterior descending coronary artery anastomosis was performed using off-pump CABG, a novel intervention in an infant with congenital left main coronary artery stenosis. Postoperative recovery was smooth and three-year follow-up demonstrated normal development with significant improvement in left ventricular function (ejection fraction 55%). To our knowledge, this case represents the first successful application of off-pump CABG in an infant with congenital left main coronary artery stenosis, marking a pioneering step in pediatric cardiac surgery.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"853-855"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144593323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Complications After Congenital Heart Surgery: Review With a Focus on Computed Tomography Imaging.","authors":"Kardos Marek","doi":"10.1177/21501351251347937","DOIUrl":"10.1177/21501351251347937","url":null,"abstract":"<p><p>Patients who have undergone congenital heart surgery often require evaluation for potential complications in the immediate postoperative period, as well as ongoing imaging surveillance to monitor for long-term complications. Computed tomography is an excellent modality for evaluating potentional complications after congenital heart surgery. The purpose of this article is to provide a pictorial review of the potential complications of a wide spectrum of congenital heart surgical procedures.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"845-852"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144602733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Rare Case of Multiple Large Unruptured Sinus of Valsalva Aneurysms in a Child.","authors":"Volodymyr Vashkeba, Bohdan Hulitskyi, Vasyl Karpenko, Alla Kolch, Liudmyla Shapoval, Lidiia Stetsenko, Stepan Maruniak, Borys Todurov","doi":"10.1177/21501351251345790","DOIUrl":"10.1177/21501351251345790","url":null,"abstract":"<p><p>Congenital sinus of Valsalva aneurysm (SVA) is a rare cardiac anomaly with an incidence ranging from 0.1% to 3.5% of all congenital heart disease. Sinus of Valsalva aneurysm involving more than one sinus of Valsalva is very rare and dangerous. Valve-sparing root replacement is a safe and effective procedure that preserves growth potential for the aortic valve and has some benefits compared with valve replacement. There are limited data on valve-sparing operations in neonates and young children. In this case report, we present the surgical correction of an isolated, unruptured, multiple SVA in a 1.4-year-old child using the Yacoub II valve-sparing procedure.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"858-861"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144500007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Roberta Iacobelli, Priscilla Tifi, Gianluigi Perri, Zaccaria Ricci, Gianluca Brancaccio, Laura Ragni, Victoria d'Inzeo, Sergio Filippelli, Matteo Trezzi, Lorenzo Galletti
{"title":"Evaluation of Residual Right Ventricular Outflow Tract Obstruction After Pulmonary Valve-Sparing Repair of Tetralogy of Fallot: An Echocardiographic Study.","authors":"Roberta Iacobelli, Priscilla Tifi, Gianluigi Perri, Zaccaria Ricci, Gianluca Brancaccio, Laura Ragni, Victoria d'Inzeo, Sergio Filippelli, Matteo Trezzi, Lorenzo Galletti","doi":"10.1177/21501351251336234","DOIUrl":"10.1177/21501351251336234","url":null,"abstract":"<p><p>BackgroundPulmonary valve-sparing repair (PVSR) of Tetralogy of Fallot (TOF) provides good results in selected patients. However, recurrent right ventricular outflow tract obstruction (RVOTO) can occur requiring surgical revision. We sought to evaluate the course of RVOTO after PVSR by serial echocardiographic (ECHO) assessment.MethodsA retrospective analysis was conducted in patients who underwent PVSR of TOF at our institution. Demographic, anatomical, surgical and 2D-ECHO data were collected. The cohort was divided into two groups: no reintervention group (group 1) and reintervention group (group 2).ResultsNinety-one patients were included in this study; 13 patients (14%) required reintervention. Right ventricular outflow tract ECHO peak gradient was significantly higher in group 2 at intraoperative transesophageal ECHO (iTEE) (<i>P</i> = .009), at hospital discharge (<i>P</i> = .021), at six months follow-up (<i>P</i> = .0001) and 12 to 36 months follow-up (<i>P</i> = .0001). A more prevalent subvalvular stenosis was found in group 2 at six months (<i>P</i> = .0011) and 12 to 36 months follow-up (<i>P</i> = .00069). An RVOT ECHO peak gradient of 30 mm Hg at iTEE (<i>P</i> = .025) and discharge (<i>P</i> = .011) was statistically associated with the need for reintervention.ConclusionsRight ventricular outflow tract peak gradient was significantly higher in group 2 than in group 1 at iTEE, discharge and follow-up, with an ECHO peak gradient of 30 mm Hg being predictive of reintervention At follow-up, residual RVOTO was prevalent at the subvalvular level in group 2. This information will be useful in clinical decision-making for TOF patients undergoing pulmonary valve sparing repair.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"790-800"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504781/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Thomas G Saba, David N Schidlow, Necia Sabin, Stephanie M Ware
{"title":"Report of Facing Heterotaxy Together 2024: A Virtual, Multidisciplinary Scientific Conference.","authors":"Thomas G Saba, David N Schidlow, Necia Sabin, Stephanie M Ware","doi":"10.1177/21501351251345795","DOIUrl":"10.1177/21501351251345795","url":null,"abstract":"<p><p>Heterotaxy is a rare condition involving abnormal arrangement of organs across the left-right axis of the body. It is associated with variable morphological and functional impairments of multiple organ systems and significant morbidity and mortality. Optimal patient care and innovative research require consistent definitions, standardized multidisciplinary practice guidelines, local clinical champions, and a centralized national registry. The Heterotaxy Research and Clinical Care Collaborative and Heterotaxy Connection conducted a virtual scientific conference for expert clinicians, scientists, patients, and families, to discuss state-of-the-art knowledge and establish networks to promote and improve heterotaxy research and clinical care.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"839-844"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Helping Each Other Help Our Patients: A Moral Imperative.","authors":"David M Overman","doi":"10.1177/21501351251341240","DOIUrl":"10.1177/21501351251341240","url":null,"abstract":"","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"719-728"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144487607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mario O'Connor, Andrew Well, Maria E Hoyos, Catherine E Stauber, Charles D Fraser, Hugo Martinez
{"title":"Surgical Intervention in Pediatric Marfan Syndrome: A Multiinstitutional Study.","authors":"Mario O'Connor, Andrew Well, Maria E Hoyos, Catherine E Stauber, Charles D Fraser, Hugo Martinez","doi":"10.1177/21501351251335474","DOIUrl":"10.1177/21501351251335474","url":null,"abstract":"<p><p>BackgroundIndividuals with Marfan syndrome (MFS) are at risk for the development of cardiovascular complications. Although the majority of MFS patients do not require cardiac surgery until adulthood, cardiovascular disease in the pediatric MFS population is still notable.MethodsThis is a retrospective of the Pediatric Health Information System from January 2004 to December 2023. All patients <18 years of age with a diagnosis of MFS who underwent aortic (Ao) and/or mitral valve (MV) surgery were included.ResultsA total of 343 patients were identified, with 115 (34%) females, 190 (55%) White non-Hispanic, and a median age of 13.0 [interquartile range (IQR): 9.0-16.0] years at surgery. Among the cohort, 241/343 (70%) underwent an aortic procedure, 40/343 (12%) aortic + MV procedure, and 62/343 (18%) MV procedure. Median hospital length of stay was 6.0 [IQR: 5.0-9.5] days, 9/343 (3%) patients required extracorporeal membrane oxygenation, and 4/343 (1%) died in-hospital. Freedom from any reintervention at 15 years was 48.8% (95% CI: 34.0-70.0). Multivariable Cox regression analysis revealed that older age at the time of surgery was associated with a reduced risk of reintervention (hazard ratio: 0.94; 95% CI: 0.89-0.99, <i>p</i> = 0.023). The overall survival rate at 15 years was 94.2% (95% CI: 90.5-98.0), and no factors were associated with increased mortality.ConclusionsOperations for cardiovascular complications of MFS can be performed safely in appropriately selected children with low morbidity and mortality and with good short-term and long-term outcomes. These findings support the safety and efficacy of surgical intervention in this population.</p>","PeriodicalId":94270,"journal":{"name":"World journal for pediatric & congenital heart surgery","volume":" ","pages":"782-789"},"PeriodicalIF":0.0,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504790/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144083121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}