Outcomes of Atrioventricular Septal Defect Repair: Two-Institutions, 10-Year Experience in Cordoba, Argentina.

Abstract

Background: Outcomes following surgical repair of atrioventricular septal defect have improved over the last decades. Global mortality for repair of this defect is approximately 3.5%. We describe contemporary surgical outcomes from two institutions in Argentina.

Material and methods: A retrospective two-institution review was performed of patients operated on for atrioventricular septal defect (partial, transitional, and complete) at Hospital Privado Universitario de Cordoba and Hospital de Niños Cordoba, from January 2014 to December 2023. We analyzed demographic characteristics, operative data, mortality, and outcomes.

Results: One hundred and ten patients were operated for atrioventricular septal defect: There were 78 patients with complete atrioventricular septal defect, 10 with partial atrioventricular septal defect, and 22 with transitional atrioventricular septal defect. Mean age and weight at operation were 1.17 year (range 0.04-13 years) and 7.53 kg (2.8-55 kg), respectively. For the complete atrioventricular septal defect subgroup, surgeries with the modified single patch technique had shorter cardiopulmonary bypass times when compared with the two patch technique (95.6 vs 139.7 min, respectively, P < .001). Hospital mortality was 4.5% (5 of 110 patients), all with complete atrioventricular septal defect operated with the double patch technique. Mean follow-up of the entire cohort was 57.4 months (1-118 months). Five patients underwent a reoperation at a mean time from the first operation of 14.4 months (6-24 months).

Conclusions: Atrioventricular septal defect surgical repair was successfully achieved in different ages and anatomical subtypes in most patients. Complete atrioventricular septal defect had higher mortality when compared with other subgroups. Our review shows similar outcomes following repair of atrioventricular septal defect compared with an international aggregate in a resource-limited practice.