Outcomes of Atrioventricular Septal Defect Repair: Two-Institutions, 10-Year Experience in Cordoba, Argentina.

Ignacio Juaneda, Lucca Pizzulli, Paula Ferrari, Rodrigo Molinas, Juan Diaz, Irma Azar, Alejandro Allub, Ernesto Juaneda, James St Louis, Alejandro Peirone, Jenkins Kathy
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Abstract

BackgroundOutcomes following surgical repair of atrioventricular septal defect have improved over the last decades. Global mortality for repair of this defect is approximately 3.5%. We describe contemporary surgical outcomes from two institutions in Argentina.Material and MethodsA retrospective two-institution review was performed of patients operated on for atrioventricular septal defect (partial, transitional, and complete) at Hospital Privado Universitario de Cordoba and Hospital de Niños Cordoba, from January 2014 to December 2023. We analyzed demographic characteristics, operative data, mortality, and outcomes.ResultsOne hundred and ten patients were operated for atrioventricular septal defect: There were 78 patients with complete atrioventricular septal defect, 10 with partial atrioventricular septal defect, and 22 with transitional atrioventricular septal defect. Mean age and weight at operation were 1.17 year (range 0.04-13 years) and 7.53 kg (2.8-55 kg), respectively. For the complete atrioventricular septal defect subgroup, surgeries with the modified single patch technique had shorter cardiopulmonary bypass times when compared with the two patch technique (95.6 vs 139.7 min, respectively, P < .001). Hospital mortality was 4.5% (5 of 110 patients), all with complete atrioventricular septal defect operated with the double patch technique. Mean follow-up of the entire cohort was 57.4 months (1-118 months). Five patients underwent a reoperation at a mean time from the first operation of 14.4 months (6-24 months).ConclusionsAtrioventricular septal defect surgical repair was successfully achieved in different ages and anatomical subtypes in most patients. Complete atrioventricular septal defect had higher mortality when compared with other subgroups. Our review shows similar outcomes following repair of atrioventricular septal defect compared with an international aggregate in a resource-limited practice.

房室间隔缺损修复的结果:阿根廷科尔多瓦的两个机构,10年的经验。
背景:在过去的几十年里,手术修复房室间隔缺损的结果有所改善。修复这一缺陷的全球死亡率约为3.5%。我们描述当代手术结果从两个机构在阿根廷。材料和方法:回顾性分析2014年1月至2023年12月在科尔多瓦私立大学医院和Niños科尔多瓦医院接受房室间隔缺损手术的患者(部分、过渡和完全)。我们分析了人口统计学特征、手术数据、死亡率和预后。结果:110例房室间隔缺损手术治疗,完全性房室间隔缺损78例,部分性房室间隔缺损10例,过渡性房室间隔缺损22例。手术时平均年龄和体重分别为1.17岁(0.04 ~ 13岁)和7.53 kg (2.8 ~ 55 kg)。对于完全性房室间隔缺损亚组,改良单补片技术比双补片技术的体外循环时间更短(分别为95.6 min和139.7 min)。结论:大多数患者在不同年龄和解剖类型的房室间隔缺损手术修复均成功。与其他亚组相比,完全性房室间隔缺损的死亡率更高。我们的回顾显示,在资源有限的实践中,与国际上的综合治疗相比,房室间隔缺损修复的结果相似。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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