Turk psikiyatri dergisi = Turkish journal of psychiatry最新文献

{"title":"Association Between Sirtuin 1 (SIRT1) Gene Polymorphisms and Suicide Attempts in Schizophrenia: An Exploratory Study.","authors":"Ekrem Furkan Uçak, Memduha Aydin, Nadir Koçak","doi":"10.5080/u27771","DOIUrl":"10.5080/u27771","url":null,"abstract":"<p><strong>Objective: </strong>Schizophrenia is a neuropsychiatric disorder with a high risk of suicide, arising from the interplay between genetic predisposition and environmental factors. The Sirtuin 1 (SIRT1) gene, an NAD⁺- dependent deacetylase, is involved in cellular stress response, apoptosis, and mitochondrial functions, as well as neuroprotection and circadian rhythm regulation. SIRT1 is thought to influence neurobiological mechanisms related to cognitive and affective regulation. This study aimed to investigate the association between specific SIRT1 gene polymorphisms and suicide attempts in patients with schizophrenia.</p><p><strong>Methods: </strong>This cross-sectional, observational genetic association study included only a case group comprising 100 patients diagnosed with schizophrenia. Targeted sequencing of the SIRT1 gene, encompassing all coding exons and their exon-intron junctions, was performed. Based on minor allele frequency and technical quality criteria, 10 single nucleotide polymorphisms (SNPs) were selected for further analysis. Linkage disequilibrium (LD) assessment, haplotype structure, and genetic modeling were conducted using the SHEsis software platform.</p><p><strong>Results: </strong>The rs10997870 GG genotype (p=0.017) and the rs7896005 AA genotype (p=0.033) were associated with suicide attempts, whereas the rs2236318 A allele (p=0.015) and the rs41299232 GG genotype (p=0.027) were found to be protective. The C-T-A-G haplotype (p=0.005) was associated with an increased risk, while the G-A-G-T haplotype (p=0.032) showed a protective effect.</p><p><strong>Conclusion: </strong>Certain polymorphisms and haplotypes within the SIRT1 gene may be associated with suicide risk among patients with schizophrenia. These findings point to the potential role of genetic profiling in identifying high-risk individuals. Further large-scale studies are warranted to increase the generalizability of the findings and to elucidate the underlying mechanisms in greater detail.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"64"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811949/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatitis C Prevalence, HCV awareness and Certain Psychological Factors in Patients with Opioid Use Disorder.","authors":"Oğuzhan Doğan, Yasemin Olgun Sunan, Fatma Duru, Gülten Kartepe, Esra Erdoğan Yarikkaya, Betül Özsoy, Gökhan Öz, Şerif Kahraman, Gökhan Tatli, Hidayet Öner","doi":"10.5080/u27182","DOIUrl":"10.5080/u27182","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to determine the prevalance of Hepatitis C Virus (HCV) in patients with Opioid Use Disorder and to investigate both the sociodemographic and psychological differences between patients with or without Hepatitis C Virus.</p><p><strong>Method: </strong>Blood samples were taken from patients diagnosed with Opioid Use Disorder (OUD) who applied to Mersin Provincial Health Directorate Toros State Hospital Alcohol and Drug Addiction Treatment Center (AMATEM) between 01.09.2019-01.09.2020 and hepatitis virus markers, complete blood count and basic biochemistry were assessed. Sociodemographic Evaluation Form, Barratt Impulsivity Scale, Childhood Traumas Scale, Drug Use Disorders Identification Test (DUDIT), Temps-A Temperament Scale, Difficulty in Emotion Regulation Scale were applied to 107 patients with HCV and 101 patients without HCV who were selected by systematic sampling and the findings obtained were compared.</p><p><strong>Results: </strong>Of the 1190 patients diagnosed with Opioid Use Disorder, 340 (28.5%) were found to be HCV positive. 107 HCV-positive and 101 HCV- negative patients who were selected for comparison were similar in terms of sociodemographic characteristics. Among HCV positive patients, the rate of intravenous drug use and needle sharing were significantly higher (p<0.001, p<0.001). Overall duration of substance use and intravenous substance use were significantly higher in HCV positive patients (p=0.024 and p=0.017). Similarly, HCV positive group were significantly more likely (p<0.001) to have heard of HCV before and significantly more likely (p=0.009) to know that HCV causes cirrhosis and liver cancer. Regarding the scores of Barratt Impulsivity Scale, Childhood Traumas Scale, Substance Use Disorder Recognition Test, DUDIT, Temps -A Temperament Scales applied to HCV positive and HCV negative patients with Opioid Use Disorder, no difference was found. The scores of the 'Non-Acceptance' factor of the Difficulties in Emotion Regulation Scale were found to be significantly higher in HCV positive patients with Opioid Use Disorder (p=0.020).</p><p><strong>Conclusion: </strong>Patients diagnosed with Opioid Use Disorder (OUD) have higher rates of HCV positivity compared to general public. Intravenous drug use significantly increases this risk. Half of HCV-positive patients were unaware that they have the virus and only a very small proportion received treatment. Therefore, examining each patient with OUD for HCV, treating positive patients in an effective referral system seems to be the an important step in the eradication of this disease in this population.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Social Media Use, Intolerance of Uncertainty, and Resilience with Anxiety and Depression Symptoms in Cancer Patients.","authors":"Gonca Aşut, Selvi Ceran, Gamze Özçürümez Bilgili","doi":"10.5080/u27431","DOIUrl":"10.5080/u27431","url":null,"abstract":"<p><strong>Objectives: </strong>The COVID-19 pandemic may be considered as a shared source of uncertainty. Prolonged engagement with social media regarding this uncertainty could present as a risk factor for anxiety. We sought to investigate the relationship between intolerance of uncertainty, dimensions of resilience, uncertainty source (pandemic)-related social media use, and the risk of anxiety and depression in patients with cancer.</p><p><strong>Method: </strong>Patients with solid organ cancer (n=113) completed the sociodemographic data form, the Intolerance to Uncertainty Scale-12 (IUS-12), the Resilience Scale for Adults (RSA) and the Hospital Anxiety and Depression Scale (HADS) between May and August 2020.</p><p><strong>Results: </strong>Depression scores were high at 17.7% of the patients while anxiety scores were high at 49.6%. RSA and its dimensions significantly differ between the Anxiety and Depression groups determined by the HADS. Time spent on social media about the COVID-19 pandemic (SMT) was associated with higher HADS-Anxiety scores (r=0.26, p<0.01), whereas higher resilience was associated with lower HADS- Anxiety (r=-0.42, p<0.01) and HADS-Depression (r=-0.52, p<0.01) scores. In addition to high levels of intolerance of uncertainty, low levels of the social resources were found to be a risk factor for depression, and low levels of self- and future-perception dimensions were found to be a risk factor for anxiety, regardless of the patients' social media use.</p><p><strong>Conclusion: </strong>As the factors that fuel uncertainty will always have an affect on cancer patients and cancer care, promoting the patients' resilience resources should be one of the main priorities for cancer patients.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial Hemiplegic Migraine (FHM) with Transient Psychotic Symptoms: A Case Report and Literature Review.","authors":"Tayfun Öz, Şeref Can Gürel","doi":"10.5080/u27678","DOIUrl":"10.5080/u27678","url":null,"abstract":"<p><p>Familial hemiplegic migraine (FHM) is a rare, autosomal dominant subtype of migraine characterized by transient hemiparesis and neurological symptoms. It is primarily associated with mutations in the CACNA1A, ATP1A2, and SCN1A genes, which disrupt neuronal excitability and contribute to complex clinical presentations. Although psychotic symptoms accompanying migraine attacks in FHM are exceedingly rare, they have been documented in a limited number of cases. This article presents a case of FHM diagnosed in a patient who exhibited transient psychotic symptoms during a migraine attack, with a focus on diagnostic and therapeutic approaches. The case is discussed in comparison to other rare instances reported in the literature. Psychotic symptoms in FHM are thought to arise from mechanisms such as cortical spreading depression and cerebral hypoperfusion. These symptoms are typically short-lived and respond rapidly to antipsychotic treatment. However, careful evaluation is essential to differentiate these episodes from primary psychotic disorders, thereby avoiding unnecessary prolonged antipsychotic use. This case underscores the importance of a thorough clinical assessment in FHM patients presenting with atypical psychiatric manifestations. The article aims to contribute to the understanding and management of psychotic symptoms in FHM, emphasizing the need for a multidisciplinary approach to diagnosis and treatment. Further research is warranted to elucidate the pathophysiology of psychosis in FHM and to optimize therapeutic strategies for this rare but clinically significant presentation. Keyword: Case report, cortical spreading depression, familial hemiplegic migraine, psychotic disorders.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Secondary Traumatic Stress, Anxiety, Depression, and Coping Styles in Healthcare Workers After the Kahramanmaraş 2023 Earthquakes.","authors":"Merve Onat, Metin Yiğit, Neslihan Kayademir, Hanife Avci, Gülser Şenses Dinç, Esra Çöp","doi":"10.5080/u27571","DOIUrl":"10.5080/u27571","url":null,"abstract":"<p><strong>Objective: </strong>The aim was to determine the relationship between secondary traumatic stress, anxiety, depression, and coping styles in healthcare workers following the devastating 2023 Kahramanmaraş earthquakes.</p><p><strong>Method: </strong>A total of 243 healthcare workers aged 18-65 years working at Ankara Bilkent City Children&rsquo;s Hospital between April 2023 and June 2023 were included in our study. Participants were assessed with the Brief Symptom Inventory, Ways of Coping with Stress Scale and Secondary Traumatic Stress Scale.</p><p><strong>Results: </strong>Anxiety, depression and secondary traumatic stress were positively correlated with ineffective coping styles and negatively correlated with effective coping styles. Younger age and female gender were associated with higher levels of anxiety and depression, while secondary traumatic stress was more prevalent among those involved in treating earthquake-affected patients. Regression analysis revealed that ineffective coping styles were associated with anxiety, depression and secondary traumatic stress. Additionally, time spent treating earthquakeaffected patients was linked to secondary traumatic stress, and the loss of a relative was associated with anxiety.</p><p><strong>Conclusion: </strong>Healthcare workers relying more on ineffective coping styles may face a greater risk of anxiety, depression and secondary traumatic stress.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"395-403"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Off-label Prescribing of Clozapine and Safety.","authors":"Nevena Divac, Igor Jakovčevski","doi":"10.5080/u27655","DOIUrl":"10.5080/u27655","url":null,"abstract":"<p><p>Clozapine is a unique antipsychotic primarily indicated for treatmentresistant schizophrenia, recurrent suicidal behavior in schizophrenia or schizoaffective disorder, and psychotic disorders in Parkinson&rsquo;s disease. It is also prescribed off-label in selected patients with mood disorders, personality disorders, or post-traumatic stress disorder. Despite its efficacy, clozapine is underprescribed due to concerns regarding adverse effects, particularly agranulocytosis. This narrative review aims to summarize the reported results regarding the off-label use of clozapine and analyze the potential risks and benefits of these practices. Offlabel prescribing, which involves using medications for unapproved indications, is common in psychiatry due to the insufficient effectiveness of many approved treatments. Clozapine, even at relatively low doses, has shown potential clinical benefits in patients with bipolar disorder, borderline personality disorder, and post-traumatic stress disorder. However, its off-label use remains limited due to safety concerns. The safety concerns associated with clozapine include agranulocytosis, myocarditis, cardiomyopathy, seizures, and metabolic syndrome. The prevention of agranulocytosis, a severe reduction in white blood cells, requires regular monitoring of blood counts. Myocarditis and cardiomyopathy necessitate careful cardiological monitoring, especially during the first month of treatment. Seizures can occur, particularly at higher doses, and metabolic syndrome, including weight gain, diabetes, and hyperlipidemia, requires ongoing management. Other adverse effects such as constipation, hypersalivation, and sedation can also impact patient compliance and quality of life. Despite these risks, with careful patient selection, individualized dosing, and continuous monitoring, the therapeutic potential of clozapine in off-label indications warrants further exploration in clinical trials. Keywords: Adverse effects, clozapine, mood disorders, off-label prescribing, personality disorders, post-traumatic stress disorder.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of 40-Session Repetitive Transcranial Magnetic Stimulation in Tourette Syndrome: A 6-Month Follow-Up Case Report.","authors":"Elif Özcan Tozoğlu, Nilifer Gürbüzer","doi":"10.5080/u27551","DOIUrl":"10.5080/u27551","url":null,"abstract":"<p><p>Tourette Syndrome (TS) is a neurodevelopmental disorder characterized by multiple motor tics and at least one vocal tic. This case report presents a patient who did not respond adequately to pharmacotherapy, highlighting the effects of repetitive transcranial magnetic stimulation (rTMS) and the outcomes of longitudinal follow-up. The patient is a 25-year-old male with no history of other physical illnesses. His symptoms began 17 years ago with simple motor tics, which gradually progressed to include complex motor and vocal tics. Over time, he also developed irritability and a persistent sense of impending doom. Clinical evaluation led to diagnoses of Tourette Syndrome comorbid with generalized anxiety disorder. Pharmacological treatment included escitalopram (10 mg/day), followed sequentially by pimozide (4 mg/day), tetrabenazine (3*25 mg/day), and aripiprazole (10 mg/day). Pimozide and aripiprazole showed no effect on the tics, and tetrabenazine was discontinued due to intolerable gastrointestinal side effects. Escitalopram, which effectively managed the patient&rsquo;s anxiety, was continued at 10 mg/day. The patient then underwent 40 sessions of rTMS over eight weeks, targeting the bilateral supplementary motor area. Each session consisted of 1 Hz stimulation at 110% of the resting motor threshold, delivering 1200 stimuli per day over 20 minutes, five days a week. Following the treatment, significant improvements were observed: a 75% reduction in the general functionality score and a 59.7% reduction in the total tic severity score. This report suggests that rTMS may be a promising alternative for TS patients with psychiatric comorbidities, particularly those who cannot tolerate medications or achieve sufficient symptom control through pharmacotherapy alone. Keywords: Tourette&rsquo;s Syndrome, Repetitive Transcranial Magnetic Stimulation, Supplementary Motor Area.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychometric Properties of Turkish Instruments Assessing Social Cognition in Psychiatry and Neurology: A Systematic Review.","authors":"Doğukan Koçyiğit, Mehmet Eren Kilinç, Rana Nüve Yilmaz, Emre Mutlu, Yavuz Ayhan","doi":"10.5080/u27665","DOIUrl":"10.5080/u27665","url":null,"abstract":"<p><strong>Objective: </strong>Social cognitive processes are shaped by cultural norms, necessitating cultural adaptation and psychometric validation. This review systematically examines Turkish tools used to assess social cognition in neurology and psychiatry, summarizing their procedures and psychometric properties.</p><p><strong>Method: </strong>Following PRISMA 2020, we searched MEDLINE, Web of Science, Scopus, and YOKSIS for studies up to May 2024. Using SRAccelerator&rsquo;s Polyglot, we developed database-specific keywords and applied a PICOS-based search strategy. From 3,115 identified records, 157 studies met inclusion criteria. Among the Turkish tools used to assess social cognition in psychiatric disorders or neurological diseases, those with established validity and reliability, we extracted (i) task characteristics and (ii) psychometric properties.</p><p><strong>Results: </strong>A total of 31 tests and 15 scales were used across 157 studies, covering 37 diagnoses, 9 studies with family members, and 2 with highrisk groups. Psychometric properties were reported for 13 tests (41.9%) and 8 scales (53.3%). Four tools were developed in Turkish: The Humor Comprehension and Appreciation Test, the Test of Perception of Affect via Nonverbal Cues, the Dokuz Eyl&uuml;l Theory of Mind Index, and the Child- Adolescent KA-SI Empathic Tendency Scale. The most frequently used test was the Reading the Mind in the Eyes Test (52.2%), while the Dokuz Eyl&uuml;l Theory of Mind Index (45.8%) was the most used scale. The Faux Pas Test and the Observable Social Cognition Scale had stronger psychometric support. Internal consistency, test-retest, and inter-rater reliability were assessed in 75%, 55%, and 30% of tools, respectively, while various validity measures ranged from 45% (known-group validity) to 5% (ecological validity). No test assessed social perception. The only tool that uses moviebased material in Turkish was the Test of Perception of Affect Via Nonverbal Cues.</p><p><strong>Conclusion: </strong>This systematic review provides a comprehensive approach to Turkish social cognition tools in neuropsychiatry. Nearly half lack robust psychometric validation, and there is a critical gap in Turkish tools measuring social perception.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"414-426"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Prevalence and Determinants of Mental Health Problems in Lebanon: A Meta-Analytic Study of 3957 Healthcare Workers.","authors":"Maher Ghandour, Najwa El Gerges, Nancy Zeaiter","doi":"10.5080/u27427","DOIUrl":"10.5080/u27427","url":null,"abstract":"<p><strong>Objective: </strong>Healthcare workers are continuously exposed to challenging environments, making them liable for poor mental health. The COVID-19 pandemic exacerbated this problem, however available data in Lebanon is scarce. We conducted this investigation to provide comprehensive evidence on the mental health of Lebanese healthcare workers.</p><p><strong>Methods: </strong>In this systematic review, we analyzed 3957 workers reported in 15 cross-sectional studies (10 during and five before the pandemic), identified after searching four databases. Examined mental health problems included depression, anxiety, stress, posttraumatic stress disorder (PTSD), and poor sleep quality. STATA software was used to pool the prevalence across studies. Subgroup analyses were performed based on the pandemic status, severity of mental health problems, and healthcare worker type. Gender and marital status were analyzed as potential risk factors. The methodological quality of all included studies was good as per the National Institute of Health risk of bias tool.</p><p><strong>Results: </strong>Anxiety, depression, stress, PTSD, insomnia, and poor sleep quality were reported in 50%, 52%, 50%, 35%, 45%, and 41% of the population, respectively. Most cases had mild anxiety (40%), mild depression (45%), but severe stress (27%). Depression and anxiety were highest among pharmacists (69% and 56%) and nurses (49% and 45%), respectively. Compared to the pre-pandemic period, depression (36% vs. 62%) and anxiety (30% vs. 56%) rates were higher during the pandemic, while stress levels were lower (62% vs. 45%). Both gender and marital status were insignificant predictors of depression, anxiety, stress, or PTSD.</p><p><strong>Conclusions: </strong>Depression, anxiety, posttraumatic stress, insomnia, and poor sleep quality are experienced by approximately one in every two Lebanese healthcare workers. The rate of depression and anxiety almost doubled during the pandemic with higher rates among pharmacists and nurses than physicians and residents. Both gender and marital status were deemed insignificant predictors of reported mental health problems.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"17"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Psychopathological Reading of the Blood Sweat Phenomenon and Religious Stigmas: The Case of Blessed Elena Aiello.","authors":"Francisco Pérez-Fernández, María Peñaranda-Ortega","doi":"10.5080/u27342","DOIUrl":"10.5080/u27342","url":null,"abstract":"<p><p>Around 300 cases of stigma have been described since the 13th century. Hematidrosis, hemolacria, bloody otorrhea, vicarious menstruation, and Gardner-Diamond syndrome are dermatological manifestations that are also observed in cases of stigma. This paper presents the disconcerting circumstances in the life of the Blessed Elena Aiello. From 1923 until her death, she suffered severe hematidrosis blood sweating on her forehead, hands, feet and knees, just as stigmata appear at the crucifixion of Jesus Christ. Stigmas, in Christian tradition, are marks corresponding to those left on Christ's body by the torture and the Crucifixion, it's said that are impressed on the person body by divine favor. These episodes, among the few recognised as authentic by the Catholic Church would appear each Friday in Lent, particularly on Good Friday. In this unique case study, doctors Fabrizio and Turano performed a medical study where the origin of the sores was unclear. Neurologist and psychiatrist Vincenzo Bianchi, on assessing the case, raised the possibility of simulation or mere suggestion on the part of the patient.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"9"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987521/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}