Turk psikiyatri dergisi = Turkish journal of psychiatry最新文献

{"title":"The Mediating Role of Social Comparison Between Parental Self-Efficacy and Sharenting.","authors":"Fatih Bayraktar, Dilek Çelik","doi":"10.5080/u27387","DOIUrl":"10.5080/u27387","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to examine the relationship of sharenting with variables that are theoretically related with the concept. Sharenting includes the basic motivation to share parental practices with others and can be associated with social comparison and parental self-efficacy. In this context, we hypothesized that the social comparison could be a mediating variable between parental self-efficacy and sharing.</p><p><strong>Method: </strong>The participants were 558 parents (456 mothers 81.7% and 102 fathers 18.3%) from Türkiye and Northern Cyprus. The age range was 19 to 53 (M=33.59, SD=5.98). Sharenting Questionnaire, Parental Social Comparison Orientation Measure and The Self-Efficacy for Parenting Tasks Index were used as measurement tools. The data was collected online by using convenience sampling method.</p><p><strong>Results: </strong>In two separate Hierarchical Regression Analyses (HRA) parental social comparison predicted sharenting and perceived parental emotional availability predicted parental social comparison significantly. Mediation analysis indicated that parental social comparison mediated between parental emotional availability and sharenting.</p><p><strong>Conclusion: </strong>Sharenting can be used to strengthen the parent-child relationship. Our research indicated that the parents who compare themselves with other parents were less available emotionally in their relationship with their children.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987531/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Candidate Genetic Markers for Post Traumatic Stress Disorder Within the Scope of Forensic Psychiatry.","authors":"Sertaç Ak, Lale Şatiroğlu Tufan, Esen Ağaoğlu, Ebru Turgut Şenel, Şeref Can Gürel, Aysun Balseven Odabaşi, Gürol Cantürk","doi":"10.5080/u27445","DOIUrl":"10.5080/u27445","url":null,"abstract":"<p><strong>Objective: </strong>This study was conducted to investigate the role of two candidate polymorphisms to improve the diagnosis of Post-Traumatic Stress Disorder (PTSD) in forensic psychiatry settings.</p><p><strong>Methods: </strong>Individuals who applied to our unit with PTSD symptoms following a traffic accident were included. The control group consisted of people who had experienced a similar accident without any symptoms. Sociodemographic data-form, Hamilton Depression Rating Scale and Anxiety Sensitivity Index-3 (ASI 3) were applied to the patients and controls, and the frequencies of the rs8042149 polymorphic allele of the RORA gene and the rs717947 polymorphic allele (4p15) were investigated.</p><p><strong>Results: </strong>A total of 103 people were included (54 case, 49 control). The rates of polymorphisms were not different between the groups. Higher education levels were associated with lower PTSD incidence while higher scores in the Social Subscale of ASI strongly predicted the occurrence of PTSD.</p><p><strong>Conclusion: </strong>The polymorphisms assessed did not help to differentiate the groups in the current sample. The potential of the Social Subscale of ASI-3 in predicting the occurrence of PTSD following a trauma should be evaluated in a longitudinal design.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"21"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Turkish Version of the Psychotropic Related Sexual Dysfunction Questionnaire (PRSEXDQ-T): Validity and Reliability in Patients Using Selective Serotonin Reuptake Inhibitor.","authors":"Yasir Şafak, Simge Nur Kurt Kaya, Rıza Gökçer Tulaci","doi":"10.5080/u27318","DOIUrl":"10.5080/u27318","url":null,"abstract":"<p><strong>Objective: </strong>Sexual dysfunctions (SD) are very common in patients with psychiatric disorders and may be due to the side effects of the disease or medications used. Current scales cannot distinguish whether SDs are due to psychiatric illness or medications use. The Psychotropic Associated Sexual Dysfunction Questionnaire (PRSexDQ) is a customized scale for screening SD due to drug use. Our aim is to conduct a validity and reliability study of PRSexDQ in patients using selective serotonin reuptake inhibitors (SSRIs).</p><p><strong>Method: </strong>One hundred patients who applied to psychiatry outpatient clinic and received SSRI treatment for at least 1 month were included in the study. These patients were evaluated by a psychiatrist, and completed the PRSexDQ-T, Arizona Sexual Experience Scale (ASEX), Golombok Rust Inventory Sexual Satisfaction (GRISS).</p><p><strong>Result: </strong>The Cronbach's Alpha coefficient was calculated as 0.906 for the analysis performed to evaluate the internal consistency of the PRSexDQ-T. In the item-total score analysis, the correlation of all items with the total score was found to be quite high (above 0.7). Correlation coefficients were found between 0.939 and 0.985, which was used to determine the test-retest correlation for each item, and all values were statistically significant (p<0.01). In the Pearson correlation analysis performed for validity analysis, a large positive correlation was found between PRSexDQ-T and ASEX and GRISS male-female total and subscale scores.</p><p><strong>Conclusion: </strong>The Turkish version of PRSexDQ is a valid and reliable measurement tool in the sample of patients using SSRIs to evaluate the level of sexual dysfunction.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"13"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987547/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145277081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Psychological and Psychosocial Interventions in Attention Deficit Hyperactivity Disorder: A Systematic Review.","authors":"Burcu Kahveci Öncü, Müjgan Inözü","doi":"10.5080/u27201","DOIUrl":"10.5080/u27201","url":null,"abstract":"<p><strong>Objective: </strong>Attention Deficit Hyperactivity Disorder (ADHD) is typically treated with medications however psychological and psychosocial interventions are recommended for symptoms that persist despite pharmacological treatment. This study aims to review randomized controlled trials focusing on the psychological and psychosocial interventions in the treatment of ADHD.</p><p><strong>Method: </strong>Eight databases were searched using keyword pairs \"ADHD\" and \"therapy\", \"ADHD\" and \"psychological treatment\", \"ADHD\" and \"psychosocial treatment\", \"ADHD\" and \"CBT\", \"attention deficit\" and \"therapy\", \"attention deficit\" and \"psychological treatment\", \"attention deficit\" and \"psychosocial treatment\", \"attention deficit\" and \"CBT\". The search was conducted at March 2022.</p><p><strong>Results: </strong>Forty-five studies met the inclusion criteria. Of these studies, 51% included the child and adolescent age group, 49% included the adult age. In 87% of these studies, psychosocial interventions, when implemented in addition to medication, resulted in significant improvements in ADHD symptoms.</p><p><strong>Conclusion: </strong>The results indicate that the use of psychosocial interventions, in addition to medical approaches, makes significant contributions to the treatment of ADHD. There is a need for studies investigating the effectiveness of psychosocial interventions in the treatment of ADHD in Turkiye.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"10"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987534/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hepatitis C Prevalence, HCV awareness and Certain Psychological Factors in Patients with Opioid Use Disorder.","authors":"Oğuzhan Doğan, Yasemin Olgun Sunan, Fatma Duru, Gülten Kartepe, Esra Erdoğan Yarikkaya, Betül Özsoy, Gökhan Öz, Şerif Kahraman, Gökhan Tatli, Hidayet Öner","doi":"10.5080/u27182","DOIUrl":"10.5080/u27182","url":null,"abstract":"<p><strong>Objective: </strong>The objective of this study is to determine the prevalance of Hepatitis C Virus (HCV) in patients with Opioid Use Disorder and to investigate both the sociodemographic and psychological differences between patients with or without Hepatitis C Virus.</p><p><strong>Method: </strong>Blood samples were taken from patients diagnosed with Opioid Use Disorder (OUD) who applied to Mersin Provincial Health Directorate Toros State Hospital Alcohol and Drug Addiction Treatment Center (AMATEM) between 01.09.2019-01.09.2020 and hepatitis virus markers, complete blood count and basic biochemistry were assessed. Sociodemographic Evaluation Form, Barratt Impulsivity Scale, Childhood Traumas Scale, Drug Use Disorders Identification Test (DUDIT), Temps-A Temperament Scale, Difficulty in Emotion Regulation Scale were applied to 107 patients with HCV and 101 patients without HCV who were selected by systematic sampling and the findings obtained were compared.</p><p><strong>Results: </strong>Of the 1190 patients diagnosed with Opioid Use Disorder, 340 (28.5%) were found to be HCV positive. 107 HCV-positive and 101 HCV- negative patients who were selected for comparison were similar in terms of sociodemographic characteristics. Among HCV positive patients, the rate of intravenous drug use and needle sharing were significantly higher (p<0.001, p<0.001). Overall duration of substance use and intravenous substance use were significantly higher in HCV positive patients (p=0.024 and p=0.017). Similarly, HCV positive group were significantly more likely (p<0.001) to have heard of HCV before and significantly more likely (p=0.009) to know that HCV causes cirrhosis and liver cancer. Regarding the scores of Barratt Impulsivity Scale, Childhood Traumas Scale, Substance Use Disorder Recognition Test, DUDIT, Temps -A Temperament Scales applied to HCV positive and HCV negative patients with Opioid Use Disorder, no difference was found. The scores of the 'Non-Acceptance' factor of the Difficulties in Emotion Regulation Scale were found to be significantly higher in HCV positive patients with Opioid Use Disorder (p=0.020).</p><p><strong>Conclusion: </strong>Patients diagnosed with Opioid Use Disorder (OUD) have higher rates of HCV positivity compared to general public. Intravenous drug use significantly increases this risk. Half of HCV-positive patients were unaware that they have the virus and only a very small proportion received treatment. Therefore, examining each patient with OUD for HCV, treating positive patients in an effective referral system seems to be the an important step in the eradication of this disease in this population.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"11"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987536/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Social Media Use, Intolerance of Uncertainty, and Resilience with Anxiety and Depression Symptoms in Cancer Patients.","authors":"Gonca Aşut, Selvi Ceran, Gamze Özçürümez Bilgili","doi":"10.5080/u27431","DOIUrl":"10.5080/u27431","url":null,"abstract":"<p><strong>Objectives: </strong>The COVID-19 pandemic may be considered as a shared source of uncertainty. Prolonged engagement with social media regarding this uncertainty could present as a risk factor for anxiety. We sought to investigate the relationship between intolerance of uncertainty, dimensions of resilience, uncertainty source (pandemic)-related social media use, and the risk of anxiety and depression in patients with cancer.</p><p><strong>Method: </strong>Patients with solid organ cancer (n=113) completed the sociodemographic data form, the Intolerance to Uncertainty Scale-12 (IUS-12), the Resilience Scale for Adults (RSA) and the Hospital Anxiety and Depression Scale (HADS) between May and August 2020.</p><p><strong>Results: </strong>Depression scores were high at 17.7% of the patients while anxiety scores were high at 49.6%. RSA and its dimensions significantly differ between the Anxiety and Depression groups determined by the HADS. Time spent on social media about the COVID-19 pandemic (SMT) was associated with higher HADS-Anxiety scores (r=0.26, p<0.01), whereas higher resilience was associated with lower HADS- Anxiety (r=-0.42, p<0.01) and HADS-Depression (r=-0.52, p<0.01) scores. In addition to high levels of intolerance of uncertainty, low levels of the social resources were found to be a risk factor for depression, and low levels of self- and future-perception dimensions were found to be a risk factor for anxiety, regardless of the patients' social media use.</p><p><strong>Conclusion: </strong>As the factors that fuel uncertainty will always have an affect on cancer patients and cancer care, promoting the patients' resilience resources should be one of the main priorities for cancer patients.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"22"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11987544/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Familial Hemiplegic Migraine (FHM) with Transient Psychotic Symptoms: A Case Report and Literature Review.","authors":"Tayfun Öz, Şeref Can Gürel","doi":"10.5080/u27678","DOIUrl":"10.5080/u27678","url":null,"abstract":"<p><p>Familial hemiplegic migraine (FHM) is a rare, autosomal dominant subtype of migraine characterized by transient hemiparesis and neurological symptoms. It is primarily associated with mutations in the CACNA1A, ATP1A2, and SCN1A genes, which disrupt neuronal excitability and contribute to complex clinical presentations. Although psychotic symptoms accompanying migraine attacks in FHM are exceedingly rare, they have been documented in a limited number of cases. This article presents a case of FHM diagnosed in a patient who exhibited transient psychotic symptoms during a migraine attack, with a focus on diagnostic and therapeutic approaches. The case is discussed in comparison to other rare instances reported in the literature. Psychotic symptoms in FHM are thought to arise from mechanisms such as cortical spreading depression and cerebral hypoperfusion. These symptoms are typically short-lived and respond rapidly to antipsychotic treatment. However, careful evaluation is essential to differentiate these episodes from primary psychotic disorders, thereby avoiding unnecessary prolonged antipsychotic use. This case underscores the importance of a thorough clinical assessment in FHM patients presenting with atypical psychiatric manifestations. The article aims to contribute to the understanding and management of psychotic symptoms in FHM, emphasizing the need for a multidisciplinary approach to diagnosis and treatment. Further research is warranted to elucidate the pathophysiology of psychosis in FHM and to optimize therapeutic strategies for this rare but clinically significant presentation. Keyword: Case report, cortical spreading depression, familial hemiplegic migraine, psychotic disorders.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"50"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12435334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Secondary Traumatic Stress, Anxiety, Depression, and Coping Styles in Healthcare Workers After the Kahramanmaraş 2023 Earthquakes.","authors":"Merve Onat, Metin Yiğit, Neslihan Kayademir, Hanife Avci, Gülser Şenses Dinç, Esra Çöp","doi":"10.5080/u27571","DOIUrl":"10.5080/u27571","url":null,"abstract":"<p><strong>Objective: </strong>The aim was to determine the relationship between secondary traumatic stress, anxiety, depression, and coping styles in healthcare workers following the devastating 2023 Kahramanmaraş earthquakes.</p><p><strong>Method: </strong>A total of 243 healthcare workers aged 18-65 years working at Ankara Bilkent City Children&rsquo;s Hospital between April 2023 and June 2023 were included in our study. Participants were assessed with the Brief Symptom Inventory, Ways of Coping with Stress Scale and Secondary Traumatic Stress Scale.</p><p><strong>Results: </strong>Anxiety, depression and secondary traumatic stress were positively correlated with ineffective coping styles and negatively correlated with effective coping styles. Younger age and female gender were associated with higher levels of anxiety and depression, while secondary traumatic stress was more prevalent among those involved in treating earthquake-affected patients. Regression analysis revealed that ineffective coping styles were associated with anxiety, depression and secondary traumatic stress. Additionally, time spent treating earthquakeaffected patients was linked to secondary traumatic stress, and the loss of a relative was associated with anxiety.</p><p><strong>Conclusion: </strong>Healthcare workers relying more on ineffective coping styles may face a greater risk of anxiety, depression and secondary traumatic stress.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"395-403"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Off-label Prescribing of Clozapine and Safety.","authors":"Nevena Divac, Igor Jakovčevski","doi":"10.5080/u27655","DOIUrl":"10.5080/u27655","url":null,"abstract":"<p><p>Clozapine is a unique antipsychotic primarily indicated for treatmentresistant schizophrenia, recurrent suicidal behavior in schizophrenia or schizoaffective disorder, and psychotic disorders in Parkinson&rsquo;s disease. It is also prescribed off-label in selected patients with mood disorders, personality disorders, or post-traumatic stress disorder. Despite its efficacy, clozapine is underprescribed due to concerns regarding adverse effects, particularly agranulocytosis. This narrative review aims to summarize the reported results regarding the off-label use of clozapine and analyze the potential risks and benefits of these practices. Offlabel prescribing, which involves using medications for unapproved indications, is common in psychiatry due to the insufficient effectiveness of many approved treatments. Clozapine, even at relatively low doses, has shown potential clinical benefits in patients with bipolar disorder, borderline personality disorder, and post-traumatic stress disorder. However, its off-label use remains limited due to safety concerns. The safety concerns associated with clozapine include agranulocytosis, myocarditis, cardiomyopathy, seizures, and metabolic syndrome. The prevention of agranulocytosis, a severe reduction in white blood cells, requires regular monitoring of blood counts. Myocarditis and cardiomyopathy necessitate careful cardiological monitoring, especially during the first month of treatment. Seizures can occur, particularly at higher doses, and metabolic syndrome, including weight gain, diabetes, and hyperlipidemia, requires ongoing management. Other adverse effects such as constipation, hypersalivation, and sedation can also impact patient compliance and quality of life. Despite these risks, with careful patient selection, individualized dosing, and continuous monitoring, the therapeutic potential of clozapine in off-label indications warrants further exploration in clinical trials. Keywords: Adverse effects, clozapine, mood disorders, off-label prescribing, personality disorders, post-traumatic stress disorder.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"53"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of 40-Session Repetitive Transcranial Magnetic Stimulation in Tourette Syndrome: A 6-Month Follow-Up Case Report.","authors":"Elif Özcan Tozoğlu, Nilifer Gürbüzer","doi":"10.5080/u27551","DOIUrl":"10.5080/u27551","url":null,"abstract":"<p><p>Tourette Syndrome (TS) is a neurodevelopmental disorder characterized by multiple motor tics and at least one vocal tic. This case report presents a patient who did not respond adequately to pharmacotherapy, highlighting the effects of repetitive transcranial magnetic stimulation (rTMS) and the outcomes of longitudinal follow-up. The patient is a 25-year-old male with no history of other physical illnesses. His symptoms began 17 years ago with simple motor tics, which gradually progressed to include complex motor and vocal tics. Over time, he also developed irritability and a persistent sense of impending doom. Clinical evaluation led to diagnoses of Tourette Syndrome comorbid with generalized anxiety disorder. Pharmacological treatment included escitalopram (10 mg/day), followed sequentially by pimozide (4 mg/day), tetrabenazine (3*25 mg/day), and aripiprazole (10 mg/day). Pimozide and aripiprazole showed no effect on the tics, and tetrabenazine was discontinued due to intolerable gastrointestinal side effects. Escitalopram, which effectively managed the patient&rsquo;s anxiety, was continued at 10 mg/day. The patient then underwent 40 sessions of rTMS over eight weeks, targeting the bilateral supplementary motor area. Each session consisted of 1 Hz stimulation at 110% of the resting motor threshold, delivering 1200 stimuli per day over 20 minutes, five days a week. Following the treatment, significant improvements were observed: a 75% reduction in the general functionality score and a 59.7% reduction in the total tic severity score. This report suggests that rTMS may be a promising alternative for TS patients with psychiatric comorbidities, particularly those who cannot tolerate medications or achieve sufficient symptom control through pharmacotherapy alone. Keywords: Tourette&rsquo;s Syndrome, Repetitive Transcranial Magnetic Stimulation, Supplementary Motor Area.</p>","PeriodicalId":94262,"journal":{"name":"Turk psikiyatri dergisi = Turkish journal of psychiatry","volume":"36 ","pages":"37"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12266594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145260560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}