The journal of nursing research : JNR最新文献

{"title":"Shaping Effective Interventions and Future Research.","authors":"Hung-Ru Lin","doi":"10.1097/jnr.0000000000000660","DOIUrl":"10.1097/jnr.0000000000000660","url":null,"abstract":"","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":"33 1","pages":"e367"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlation Between Handgrip Strength and Bone Density and Fragility Fracture Risk Among Older Adults: A Cross-Sectional Study.","authors":"Shyh-Geng Huang, Ru-Ping Lee, Ting-Kuo Yao, Jen-Hung Wang, Wen-Tien Wu, Kuang-Ting Yeh","doi":"10.1097/jnr.0000000000000656","DOIUrl":"10.1097/jnr.0000000000000656","url":null,"abstract":"<p><strong>Background: </strong>Population aging has led to a surge in elderly care needs worldwide. Bone aging, skeletal muscle degeneration, and osteoporosis pose critical health challenges for the elderly. The process of bone and skeletal muscle aging not only impacts the functional abilities but also increases fragility fracture risk. Although a negative correlation between handgrip strength and fragility fracture risk has been identified in elderly populations, there is a lack of related research in Taiwan.</p><p><strong>Purpose: </strong>This cross-sectional study was designed to investigate the association between handgrip strength and two outcome variables, bone density and risk of fragility fracture, in Taiwanese individuals aged 65 years and older with low bone mass.</p><p><strong>Methods: </strong>A total of 548 older adults, including 84 men and 464 women, were recruited between August 2019 and July 2021. Bone mineral density T -scores acquired using dual-energy X-ray absorptiometry scan, the total score for the Taiwan-specific Fracture Risk Assessment (FRAX) tool, and bilateral handgrip strength acquired using a digital hand dynamometer were recorded along with other factors such as comorbidities, dietary habits, and daily activities.</p><p><strong>Results: </strong>In this study, the mean age was 70.9 ( SD = 5.6) years, mean bone mass index was 24.1 ( SD = 3.5) kg/m 2 , mean FRAX main fracture risk score was 19.5% ( SD = 8.3), and mean FRAX hip fracture risk score was 7.7% ( SD = 5.7). Lumbar and hip T -scores were both significantly correlated with both dominant and nondominant handgrip strength in older woman. Older age; both lower hip and spine T -scores; both lower dominant and nondominant handgrip strengths; having Type 2 diabetes, coronary artery disease, or chronic hepatic disease; and lacking a steady job were significantly associated with a higher risk of fragility fracture.</p><p><strong>Conclusions/implications for practice: </strong>The results of this study provide important information regarding the correlation between handgrip strength and several variables, including bone mineral density T -score, FRAX score, comorbidities, and job status, among older adults. Notably, these correlations were found to be particularly strong in the female participants. This information may be used to facilitate the early identification of elderly individuals at a high risk of fragility fractures, enabling the timely development of preventive nursing strategies and the provision of targeted interventions.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":"e375"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ward-Based Staff Perspectives on Their Preparedness to Recognize Patient Deterioration: An Interpretive Description Study.","authors":"John Mikhail, Lindy King","doi":"10.1097/jnr.0000000000000658","DOIUrl":"10.1097/jnr.0000000000000658","url":null,"abstract":"<p><strong>Background: </strong>Despite an overall decline in serious adverse events in hospitalized patients, approximately one third of inpatient mortality continues to relate to adverse events impacting patients on general wards. The preparedness of nurses, midwives, and nursing assistants (collectively referred to as ward-based staff) to recognize patient deterioration is therefore seen as critical.</p><p><strong>Purpose: </strong>The aim of this study was to explore ward-based staff perspectives regarding their preparedness to recognize patient deterioration.</p><p><strong>Methods: </strong>An interpretive description approach was utilized to interview 16 participants from a single-center regional hospital. The participants included nurses, midwives, and nursing assistants who worked exclusively on wards. The participants were purposely selected to complete semistructured interviews. Data were analyzed using a six-step thematic analysis, and the study followed the Standards for Reporting Qualitative Research checklist.</p><p><strong>Results: </strong>Three main themes (with subthemes) were identified: (a) feeling prepared (experience, intuitive awareness, early warning systems), (b) promoting preparedness (multimodal education, debriefing, collegial support), and (c) being unprepared (undergraduate education, knowledge deficit, staffing related concerns, psychological response to incident, unforeseen barriers).</p><p><strong>Conclusions/implications for practice: </strong>The findings suggest strategies for increasing knowledge and confidence in all ward-based staff, allowing them to feel better prepared to recognize clinical deterioration. Moreover, based on the results, ward-based staff strongly perceive experience, clinical shortfalls in undergraduate education, collegial support networks, mentorship, psychological response to incidents, and multimodal education to be key contributors to preparedness.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":"e369"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142985904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of Preventive Health Behavior for Hepatitis B in Pregnant Women: A Cross-Sectional Study.","authors":"Ya-Wen Huang, Chich-Hsiu Hung, Mei-Chuan Huang","doi":"10.1097/jnr.0000000000000654","DOIUrl":"10.1097/jnr.0000000000000654","url":null,"abstract":"<p><strong>Background: </strong>Vertical transmission from mother to child during the perinatal period is a key route of hepatitis B infection. The infection rate among children of mothers who are hepatitis B carriers is high.</p><p><strong>Purpose: </strong>This study was designed to investigate the hepatitis-B-related preventive health behavior of pregnant women and related factors.</p><p><strong>Methods: </strong>A cross-sectional study design was used, and 184 pregnant women aged 20 years or above were recruited at obstetrics clinics as participants. The Demographic Characteristics Questionnaire, Hepatitis B Knowledge Questionnaire, Hepatitis B Health Beliefs Questionnaire, and Preventive Health Behavior Questionnaire were used to collect study data between October 2017 and March 2018.</p><p><strong>Results: </strong>Most of the participants had received a hepatitis B test because of either a pregnancy checkup (38.0%) or a health examination (32.1%), and most (77.7%) were not hepatitis B carriers. Using multiple linear regression, four significant determinants of hepatitis B preventive health behavior were identified, including marital status (β = 2.45, p = .008, 95% CI [0.66, 4.25]), test for hepatitis B infection status (β = -2.83, p = .013, 95% CI [-5.06, -0.60]), hepatitis B knowledge (β = 0.21, p = .001, 95% CI [0.09, 0.33]), and hepatitis B health beliefs (β = 0.11, p < .001, 95% CI [0.05, 0.16]).</p><p><strong>Conclusions: </strong>The participants who were not married or had never received a hepatitis B test exhibited better hepatitis-B-related preventive health behavior. Moreover, both hepatitis B knowledge and hepatitis B health belief scores were found to relate positively to preventive health behavior. Healthcare providers should strengthen health education in outpatient clinics and provide post-hepatitis B health-related materials in the community. In particular, internet resources such as hepatitis-B-related health education apps and other channels should be used to increase hepatitis B knowledge in perinatal women and eliminate hepatitis B.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":"e371"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dysmenorrhea, Premenstrual Syndrome, and Lifestyle Habits in Young University Students in Spain: A Cross-Sectional Study.","authors":"Cristina Franco-Antonio, Esperanza Santano-Mogena, Sergio Cordovilla-Guardia","doi":"10.1097/jnr.0000000000000657","DOIUrl":"10.1097/jnr.0000000000000657","url":null,"abstract":"<p><strong>Background: </strong>Menstruation is a physiological process that may be accompanied by pain, headache, edema, emotional changes, and other symptoms, all of which affect quality of life. Although the results of some studies indicate lifestyle habits can affect the menstrual cycle and associated symptoms, few have investigated this issue, and even fewer have explored the impact of these symptoms on quality of life, in Spanish women.</p><p><strong>Purpose: </strong>The objectives of this study were to determine the prevalence of dysmenorrhea and premenstrual syndrome (PMS) among students at a Spanish university, assess the impact of these conditions on quality of life, and analyze the relationship among lifestyle habits, dysmenorrhea, and PMS.</p><p><strong>Methods: </strong>A cross-sectional study was carried out on 743 women enrolled at the University of Extremadura in the 2021-2022 academic year. Data related to the menstrual cycle, pain, and PMS-related physical and emotional symptoms were collected. Quality of life related to menstruation was evaluated using the CVM-22 scale. Lifestyle data collected included adherence to a Mediterranean diet (PREDIMED [Prevención con Dieta Mediterránea] questionnaire), level of physical activity (International Physical Activity Questionnaire), and alcohol and tobacco consumption (Alcohol, Smoking, and Substance Involvement Screening Test Version 3). Also, other clinical data were recorded.</p><p><strong>Results: </strong>In terms of the sample, the median age was 21 (19-23) years, the prevalence of dysmenorrhea was 57.9%, 92.7% reported premenstrual physical symptoms, and 55.6% reported experiencing premenstrual emotional changes. Having a low level of adherence to a Mediterranean diet was associated with the presence of dysmenorrhea, with an adjusted odds ratio (aOR) of 1.47 (95% CI [1.06, 2.03]). Having a low level of physical activity was strongly associated with the presence of premenstrual physical symptoms, with an aOR of 5.89 (95% CI [1.71, 20.26]). Also, an association was found between tobacco use and premenstrual emotional changes, with an aOR of 2.02 (95% CI [1.25, 3.25]). Furthermore, dysmenorrhea and PMS were both associated with a low quality of life, with pain and emotional changes being the most significantly associated factors, with ORs of 16.25 (95% CI [10.36, 25.47]) and 26.73 (95% CI [16.46, 43.40]), respectively.</p><p><strong>Conclusions: </strong>Similar to previous studies, the findings of this study indicate a high prevalence of dysmenorrhea and PMS among young university students in western Spain, with both of these symptoms impacting quality of life significantly and negatively. In addition, lifestyle habits, diet, physical activity, and tobacco use seem to influence the occurrence of these symptoms. Promoting lifestyle changes may be an effective strategy to reduce the incidence of dysmenorrhea and PMS and improve the quality of life of young women.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":"33 1","pages":"e374"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Relationship Between Perceived Staffing and Quality of Care: The Mediating Roles of Job Satisfaction and Work Engagement.","authors":"Limin Wang, Xu Dong, Shaomei Shang","doi":"10.1097/jnr.0000000000000661","DOIUrl":"10.1097/jnr.0000000000000661","url":null,"abstract":"<p><strong>Background: </strong>Although work engagement and job satisfaction are two important indicators associated with care quality, their mediating effects on the relationship between perceived staffing and quality of care have not been adequately clarified.</p><p><strong>Purpose: </strong>This study was designed to determine the mechanism by which nurses' perceived staffing influences quality of care by clarifying the mediating roles of job satisfaction and work engagement.</p><p><strong>Methods: </strong>A cross-sectional questionnaire survey was implemented among 2,142 clinical nurses from 211 inpatient wards in 13 hospitals. Work engagement, job satisfaction, perceived staffing, and rated quality of care were measured.</p><p><strong>Results: </strong>Most (89.7%) of the respondents rated quality of care as good or better, and 56.1% perceived staffing in the wards as adequate. The two main findings of this study are as follows: (a) Perceived staffing influenced quality of care via one direct and three indirect pathways, with the indirect effect greater than the direct effect (β direct = 0.09, β total indirect = 0.25), and (b) work engagement and job satisfaction were important mediators of the impact of staffing on quality of care.</p><p><strong>Conclusion: </strong>Quality of care may be enhanced by improving the work engagement and satisfaction of nurses in their current job, suggesting an effective approach to alleviating the current nursing shortage.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":"e376"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143019443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of Nurse Educators Using Virtual Games in Nursing Education: A Qualitative Study.","authors":"Yadigar Ordu, Nurcan Calişkan","doi":"10.1097/jnr.0000000000000651","DOIUrl":"10.1097/jnr.0000000000000651","url":null,"abstract":"<p><strong>Background: </strong>Virtual games developed for educational purposes have an important place in the education of nursing students.</p><p><strong>Purpose: </strong>This study was designed to investigate the experiences of nurse educators regarding the use of virtual games in nursing education.</p><p><strong>Methods: </strong>A descriptive qualitative design was used in this research, which was conducted between June and August 2022. The participants included 18 nurse educators, all of whom were working in the nursing department at several universities in Turkey and selected using purposeful sampling. The data were collected using the Educator Information Form and the Semi-Structured Interview Form. The participants were contacted by e-mail. Participant interviews, which took approximately 30-45 minutes to complete, were conducted online via Zoom. The interviews were recorded with participant approval and then transcribed verbatim. Braun and Clarke's method and MAXQDA 2022 software were used to analyze the data.</p><p><strong>Results: </strong>Five themes were identified: (a) opinions of the nurse educators, (b) feedback received by nurse educators from students, (c) nurse educator experiences, (d) nurse educator suggestions for the use of virtual games, and (e) nurse educator suggestions for virtual game developers.</p><p><strong>Conclusions/implications for practice: </strong>The participants expressed support for using virtual games in nursing education; received both positive and negative related feedback from students; reported positive and negative experiences with these games; made suggestions for gaming methods and dissemination; and offered related planning, professional support, and other recommendations to game developers. The use of games in nursing education should be expanded, training programs should be organized for nurse educators considering game development, and similar studies should be conducted on larger study samples. The findings provide important information to nurse educators who are considering developing virtual games. The experiences of nurse educators regarding the use of virtual games are quite interesting, and the number of nurse educators involved in developing these games is quite low.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":"e368"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142840704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phenomenological Description of the Experiences of Teenagers With Critically Ill Parents.","authors":"Maya Barr, Aishwarya Thakur, Varun K Thvar, David Dupee, Nina Vasan","doi":"10.1097/jnr.0000000000000659","DOIUrl":"10.1097/jnr.0000000000000659","url":null,"abstract":"<p><strong>Background: </strong>Critical illness not only threatens the life of the patient but also may profoundly impact the lives of their loved ones. For teenagers with a critically ill parent, these impacts may have significant, developmentally impactful effects. A descriptive understanding of these effects may advance scholarly understanding of the challenges these teenagers face.</p><p><strong>Purpose: </strong>In this study, we sought to understand this overlooked population, i.e., teenagers with a critically ill parent, using a descriptive analysis of their experiences.</p><p><strong>Methods: </strong>Individual and group interviews were conducted with the participants (n = 9). Interviewers presented standardized semistructured interview questions to all of the participants. The questions explored situational, emotional, relational, and dynamic phenomena related to the experience of having a critically ill parent.</p><p><strong>Results: </strong>Themes describing the participants' lived experiences related to having a parent with a critical illness were examined using a three coding framework. Four themes emerged, including parental health interference on teenagers-fallout, worsening, and interference; emotional experience and how emotions were processed-emotions, cognitive strategies, and behavioral strategies; relationships with others-sharing feelings, company, and relationships; and information and secrecy-learning, secrecy, and history.</p><p><strong>Conclusions/implications for practice: </strong>All of the teenagers in this study were found to suffer from both situational and emotional interference. Parentification, use of selective distraction as an emotion regulation skill, and reliance on support from others were also observed. These results shed light on the overall experience of teenagers who have a critically ill parent. The fallout effects of a parent's health can encompass situational, logistical, emotional, and relationship aspects. Importantly, attention must be paid to how teenagers cope with the emotions experienced during a parent's critical illness. This framework may inform how to more effectively support teenagers through strategies such as providing peer support opportunities.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":"33 1","pages":"e370"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143061935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motivation in Rare Disease Self-Care: A Phenomenological Study of Pediatric Patients With Spinal Muscular Atrophy and Their Caregivers.","authors":"Bao-Huan Yang, Chia-Ying Chung, Yuh-Shiow Li","doi":"10.1097/jnr.0000000000000652","DOIUrl":"https://doi.org/10.1097/jnr.0000000000000652","url":null,"abstract":"<p><strong>Background: </strong>Spinal muscular atrophy can cause progressive physical disability and difficulties with self-care. Self-care motivation can enhance patient persistence in self-care behavior and maintain health.</p><p><strong>Purpose: </strong>This study was designed to explore and describe motivations for self-care among school-aged children and adolescents with spinal muscular atrophy and the perspectives of their primary caregivers.</p><p><strong>Methods: </strong>Husserl's phenomenological research method was adopted, and data were collected using in-depth, face-to-face, open-ended interviews with patients and their primary caregivers aged 8-18 years with spinal muscular atrophy. A total of eight patient-caregiver dyads were recruited via purposeful sampling from a hospital clinic and through the Muscular Dystrophy Association of Taiwan. The interviews were conducted in the participants' homes and transcribed verbatim. Data were then thematically analyzed using the Giorgi analysis method.</p><p><strong>Results: </strong>Six themes were identified from the patients' perspective: (a) adapting to dietary restrictions, (b) proactive measures for physical safety, c3) pursuing social connection and peer support, (d) navigating emotional well-being, (e) seeking independence, and (f) achieving success motivation. From the caregivers' perspective, the motivations for patient self-care were identified as follows: (a) ensuring safe and enjoyable eating for patients, (b) facilitating patient autonomy in health risk management, (c) facilitating patient engagement with peers, (d) balancing support with encouraging independence, (e) assessing and balancing independence and safety in patient caregiving, and (f) admiring patients' resilience and self-care innovation.</p><p><strong>Conclusions/implications for practice: </strong>This study highlights the vital roles of caregivers in adapting to the dynamic self-care motivations of children and adolescents and of healthcare professionals in facilitating communication and care strategies. Personalized approaches are essential for enhancing autonomy and well-being in pediatric patients.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and Quality of Life in Patients With Chronic Kidney Disease: A Mediation Analysis of Handgrip Strength and Demoralization.","authors":"Szu-Ying Lee, Yu-Wei Fang, Chieh-Yu Liu","doi":"10.1097/jnr.0000000000000645","DOIUrl":"10.1097/jnr.0000000000000645","url":null,"abstract":"<p><strong>Background: </strong>Chronic kidney disease (CKD) is a progressive disease impacting the physical function and mental health of sufferers. Depression is known to negatively impact quality of life, whereas handgrip strength and demoralization are important factors affecting physical and mental health. Lower handgrip strength has been associated with sarcopenia and higher risk of hospitalization in patients and higher workloads for nurse caregivers. Few studies have investigated the complex relations among these factors in patients with CKD.</p><p><strong>Purpose: </strong>This study was designed to investigate the mediating effects of grip strength and demoralization on the relationship between depression and quality of life in patients with CKD.</p><p><strong>Methods: </strong>Two hundred fifty patients with CKD comprised the study sample. The hypotheses were tested using the PROCESS macro.</p><p><strong>Results: </strong>Depression was found to be negatively associated with handgrip strength and quality of life but positively associated with demoralization. The results indicate that both handgrip strength and demoralization mediate the association between depression and quality of life. Moreover, the results of multiple mediation model analysis showed handgrip strength and demoralization both play important roles in the link between depression and quality of life.</p><p><strong>Conclusions: </strong>The results of this study indicate that handgrip strength and demoralization mediate the relationship between depression and quality of life in patients with CKD. Thus, increasing handgrip strength and decreasing demoralization levels may mitigate the impact of depression on quality of life. Therefore, nurses should better appreciate the importance of handgrip strength for patients with CKD and evaluate handgrip strength. Nurses should also develop physical and mental interventions to increase handgrip strength and decrease demoralization.</p>","PeriodicalId":94242,"journal":{"name":"The journal of nursing research : JNR","volume":" ","pages":"e361"},"PeriodicalIF":0.0,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142678150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}