Sulayman El Mathari, Rahul A Bhoera, Luuk H G A Hopman, Josephine Heidendael, Arjan Malekzadeh, Aart Nederveen, Pim van Ooij, Marco J W Götte, Jolanda Kluin
{"title":"Disparities in quantification of mitral valve regurgitation between cardiovascular magnetic resonance imaging and trans-thoracic echocardiography: a systematic review.","authors":"Sulayman El Mathari, Rahul A Bhoera, Luuk H G A Hopman, Josephine Heidendael, Arjan Malekzadeh, Aart Nederveen, Pim van Ooij, Marco J W Götte, Jolanda Kluin","doi":"10.1007/s10554-024-03280-y","DOIUrl":"10.1007/s10554-024-03280-y","url":null,"abstract":"<p><p>Primary mitral regurgitation (MR) is a prevalent valvular heart disease. Therapy stratification for MR depends on accurate assessment of MR severity and left ventricular (LV) dimensions. While trans-thoracic echocardiography (TTE) has been the standard/preferred assessment method, cardiovascular magnetic resonance imaging (CMR) has gained recognition for its superior assessment of LV dimensions and MR severity. Both imaging modalities have their own advantages and limitation for therapy guidance. However, the differences between the two modalities for assessing/grade severity and clinical impact of MR remains unclear. This systematic review aims to evaluate the differences between TTE and CMR in quantifying MR severity and LV dimensions, providing insights for optimal clinical management. A literature search was performed from inception up to March 21st 2023. This resulted in 2,728 articles. After screening, 22 articles were deemed eligible for inclusion in the meta-analysis. The included study variables were, mitral valve regurgitation volume (MR<sub>VOL</sub>), regurgitation fraction (MR<sub>FRAC</sub>), LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), LV stroke volume (LVSV), and LV ejection fraction (LVEF). TTE showed a significant higher MR<sub>VOL</sub> (10.4 ml, I<sup>2</sup> = 88%, p = 0.002) and MR<sub>FRAC</sub> (6.3%, I<sup>2</sup> = 51%, p = 0.05) compared to CMR, while CMR demonstrated a higher LVEDV (21.9 ml, I<sup>2</sup> = 66%, p = < 0.001) and LVESV (16.8 ml, I<sup>2</sup> = 0%, p = < 0.001) compared to TTE. Our findings demonstrate substantial disparities in TTE and CMR derived measurements for parameters that play a pivotal role in the clinical stratification guidelines. This discrepancy prompts a critical question regarding the prognostic value of both imaging modalities, which warrants future research.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"647-658"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sabin G Pop, Eva Hägler, Cristina Popescu, Irene A Burger, Alexander W Sauter
{"title":"Cardiotoxicity as important differential diagnosis for reduced myocardial blood flow during Rubidium cardiac PET/CT : Cardiotoxicity in Rubidium PET/CT.","authors":"Sabin G Pop, Eva Hägler, Cristina Popescu, Irene A Burger, Alexander W Sauter","doi":"10.1007/s10554-024-03315-4","DOIUrl":"10.1007/s10554-024-03315-4","url":null,"abstract":"<p><p>A 65-year-old woman with a history of ductal mammary carcinoma and recent autonomic dysfunction underwent a Rb-82 chloride (RbCl) cardiac PET/CT scan that showed no ischemia or scarring, but significantly reduced myocardial flow reserve (MFR) (global: 1.5) and a CAC-Score of 0. The patient's chemotherapy history (paclitaxel, carboplatin, epirubicin, pembrolizumab 2 years before) with elevated Troponin T and NT-pro-BNP levels at that time, and now reduced MFR with 0 CAC suggests cancer-therapy-related cardiotoxicity. An important differential diagnosis to the more common CAD-associated microvascular disease. Furthermore, tumor recurrence with a PET-avid lymph node metastasis was found additionally.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"817-819"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hasan Hadzalic, Daniel Fritschi, Luca Oechslin, Patric Biaggi
{"title":"Renal cell carcinoma tumor bulk extending to inferior vena cava and right atrium.","authors":"Hasan Hadzalic, Daniel Fritschi, Luca Oechslin, Patric Biaggi","doi":"10.1007/s10554-024-03303-8","DOIUrl":"10.1007/s10554-024-03303-8","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"815-816"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francesco Natale, Luigi Marotta, Paolo Golino, Giovanni Cimmino
{"title":"When a common sore throat unmasks a rare disease.","authors":"Francesco Natale, Luigi Marotta, Paolo Golino, Giovanni Cimmino","doi":"10.1007/s10554-025-03338-5","DOIUrl":"10.1007/s10554-025-03338-5","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"811-812"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143070132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"HFpEF correlated with better improvement of left atrial function in post-ablation patients with paroxysmal atrial fibrillation.","authors":"Keyue Sun, Xiaohan Qin, Dingding Zhang, Fang Fang, Rongqi Wan, Jiaqi Wang, Jiaqi Yu, Jinzhi Lai, Deyan Yang, Jingbo Fan, Zhongwei Cheng, Kangan Cheng, Peng Gao, Lihua Zhang, Hua Deng, Quan Fang, Taibo Chen, Yongtai Liu","doi":"10.1007/s10554-025-03359-0","DOIUrl":"10.1007/s10554-025-03359-0","url":null,"abstract":"<p><p>The extent of improvement in left atrial (LA) function after radiofrequency catheter ablation (RFCA) in patients with paroxysmal atrial fibrillation (PxAF) and its association with heart failure with preserved ejection fraction (HFpEF) remain unclear. This study aims to explore whether there is a difference in the improvement of LA function after RFCA in patients with PxAF combined with HFpEF compared to those without HFpEF. Patients with PxAF receiving RFCA were enrolled. LA volume index (LAVI), LA emptying fraction (LAEF), and LA peak reservoir strain (LA RS) were assessed using echocardiography at baseline and three months after RFCA. Changes in these parameters were compared between patients with a high probability of HFpEF (hp-HFpEF) and those with a medium or low probability of HFpEF (lp-HFpEF), as determined by the H2FPEF score. A total of 147 patients (mean age 62.6 years; 63.3% males) were recruited (hp-HFpEF = 30). Baseline LA function differed significantly between patients with hp-HFpEF and those with lp-HFpEF. Differences included LAVI, LAEF, and LA RS (all P < 0.01). The improvement in LA function 3 months after RFCA was significantly different between the two groups, even after adjusting for confounding factors. Specifically, patients with hp-HFpEF experienced greater reductions in LAVI, more improvement in LAEF, and greater improvement in LA RS compared to patients with lp-HFpEF. A high probability of HFpEF was correlated with greater improvement in LA function following RFCA in patients with PxAF. The clinical trial registration number: ClinicalTrials.gov NCT05266144.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"721-732"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Angeliki Papachristodoulou, Patrick Ghibes, Natalia Valeria Pentara, Maria Alexandratou, Abraham Levitin, Sameer Gadani, Sasan Partovi, Elizabeth Psoma, Vasileios Rafailidis, Panos Prassopoulos
{"title":"CT angiography of acute aortic syndrome in patients with chronic kidney disease.","authors":"Angeliki Papachristodoulou, Patrick Ghibes, Natalia Valeria Pentara, Maria Alexandratou, Abraham Levitin, Sameer Gadani, Sasan Partovi, Elizabeth Psoma, Vasileios Rafailidis, Panos Prassopoulos","doi":"10.1007/s10554-025-03336-7","DOIUrl":"10.1007/s10554-025-03336-7","url":null,"abstract":"<p><p>The term acute aortic syndrome (AAS) refers to a range of different entities, including dissection, intramural haematoma and penetrating atherosclerotic ulcer. Patients with chronic renal disease and particularly those with dominant polycystic kidney disease are susceptible to this pathology, given the underlying renal arteriopathy and hypertension. Imaging plays a crucial role in diagnosing, grading and guiding management of these patients, with computed tomography angiography (CTA) being on the frontline. Albeit of overlapping of imaging findings between these conditions, specific imaging characteristics help discriminate and guide treatment. Given the nephrotoxic contrast agent involved, tailored CTA protocols or alternative imaging modalities such as MRI or US are necessary in this patient population. This review article discusses the main imaging findings of entities found in the spectrum of AAS, as well as the appropriate use and protocol of imaging modalities, focusing on the appropriate use of nephrotoxic contrast agents, the preservation of renal function and maintenance of optimal diagnostic accuracy.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"681-693"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982094/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143030612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usefulness of two-dimensional speckle tracking echocardiography in assessment of left atrial fibrosis degree and its application in atrial fibrillation.","authors":"Yuzhe Song, Lijuan Huang, Cheng Jiang, Fang Du, Jing Zhang, Peng Chang","doi":"10.1007/s10554-025-03345-6","DOIUrl":"10.1007/s10554-025-03345-6","url":null,"abstract":"<p><p>This study aimed to establish a clinical prediction model for assessing the degree of left atrial fibrosis (LAF) in patients with atrial fibrillation (AF) by combining two-dimensional speckle tracking echocardiography (2D-STE). Additionally, the study sought to evaluate the predictive utility of 2D-STE for left atrial appendage thrombosis (LAAT) and the recurrence of AF after radiofrequency catheter ablation (RFA). A total of 195 patients with AF were included, and late gadolinium enhanced cardiac magnetic resonance was adopted to assess LAF degree. Fibrotic tissue as a percentage of total left atrial wall volume > 20% was defined as severe LAF. Echocardiographic parameters were obtained and analyzed using 2D-STE. The patients were randomly divided into two cohorts (7:3) as the training and testing cohorts. Independent predictors of severe LAF were determined via univariate and multivariate logistic regression, including age, CHA<sub>2</sub>DS<sub>2</sub>-VA score, left atrial appendage emptying fraction (LAA-EF), peak atrial longitudinal strain (PALS), left atrial stiffness index (LASI), left atrial strain during contraction phase (LASct) and left atrial strain during conduit phase (LAScd). The nomogram was established with the above variables and the area under the curve of the nomogram in testing cohorts was 0.89 (95% CI, 0.80-0.98). As validated by receiver operating characteristic curves, calibration curves and decision curve analysis, the nomogram model demonstrated promising potential for clinical application. Besides, by univariate and multivariate logistic regression analyses, CHA<sub>2</sub>DS<sub>2</sub>-VA score, uric acid, LAA-EF, left atrial appendage peak blood flow emptying velocity (LAA-PEV) and LASct were found to be independent predictors of LAAT, and left atrial appendage length, E/e' and LASct were found to be independent predictors of post-ablation AF recurrence. 2D-STE can be applied to evaluate LAF degree of AF patients and predict LAAT and AF recurrence.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"695-708"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11982115/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mitral annuloplasty ring migration.","authors":"Nauman Hussain, Cheng Ting Lin, Claire Brookmeyer","doi":"10.1007/s10554-025-03388-9","DOIUrl":"https://doi.org/10.1007/s10554-025-03388-9","url":null,"abstract":"<p><p>Mitral annuloplasty ring dehiscence is a rare post-operative complication [1, 2]. Even more rarely, dehiscent annuloplasty rings can migrate leading to vascular complications like aortic rupture and pseudoaneurysm formation [3]. This case highlights rare but severe complications of annuloplasty ring dehiscence and migration, and challenges of managing these high-risk patients.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143744537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel Raskin, Levester Kirksey, Abraham Levitin, Ali Khalifeh, Jon G Quatromoni, Sean P Lyden, Cassandra Kovach, Patrick Ghibes, Amrit Khooblall, Sasan Partovi
{"title":"Cross-sectional imaging for presurgical planning of dialysis circuit vascular access creation in the end stage renal disease patient population.","authors":"Daniel Raskin, Levester Kirksey, Abraham Levitin, Ali Khalifeh, Jon G Quatromoni, Sean P Lyden, Cassandra Kovach, Patrick Ghibes, Amrit Khooblall, Sasan Partovi","doi":"10.1007/s10554-025-03357-2","DOIUrl":"https://doi.org/10.1007/s10554-025-03357-2","url":null,"abstract":"<p><p>This systematic review explores the role of cross-sectional imaging modalities-computed tomography angiography (CTA) and magnetic resonance angiography (MRA)-in the preoperative planning of dialysis vascular access for patients with end-stage renal disease (ESRD). A systematic search was conducted using PubMed and Cochrane databases, yielding 45 studies meeting inclusion criteria. These modalities are particularly valuable in cases of complex vascular anatomy, central venous stenosis, and prior surgical interventions. Findings emphasize the advantages of CTA for detailed anatomical mapping and MRA for cases requiring soft-tissue contrast or preservation of renal function. Representative clinical cases illustrate how imaging findings directly influence surgical and endovascular decision-making, optimizing patient outcomes. This manuscript describes the role of cross-sectional imaging for dialysis circuit vascular access interventions including representative clinical examples.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143574946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dengao Li, Wen Xing, Jumin Zhao, Changcheng Shi, Fei Wang
{"title":"Multimodal deep learning for predicting in-hospital mortality in heart failure patients using longitudinal chest X-rays and electronic health records.","authors":"Dengao Li, Wen Xing, Jumin Zhao, Changcheng Shi, Fei Wang","doi":"10.1007/s10554-025-03322-z","DOIUrl":"10.1007/s10554-025-03322-z","url":null,"abstract":"<p><p>Amid an aging global population, heart failure has become a leading cause of hospitalization among older people. Its high prevalence and mortality rates underscore the importance of accurate mortality prediction for swift disease progression assessment and better patient outcomes. The evolution of artificial intelligence (AI) presents new avenues for predicting heart failure mortality. Yet current research has predominantly leveraged structured data and unstructured clinical notes from electronic health records (EHR), underutilizing the prognostic value of chest X-rays (CXRs). This study aims to harness deep learning methodologies to explore the feasibility of enhancing the precision of predicting in-hospital all-cause mortality in heart failure patients using CXRs data. We propose a novel multimodal deep learning network based on the spatially and temporally decoupled Transformer (MN-STDT) for in-hospital mortality prediction in heart failure by integrating longitudinal CXRs and structured EHR data. The MN-STDT captures spatial and temporal information from CXRs through a Hybrid Spatial Encoder and a Distance-Aware Temporal Encoder, ultimately fusing features from both modalities for predictive modeling. Initial pre-training of the spatial encoder was conducted on CheXpert, followed by full model training and evaluation on the MIMIC-IV and MIMIC-CXR datasets for mortality prediction tasks. In a comprehensive view, the MN-STDT demonstrated the best performance, with an AUC-ROC of 0.8620, surpassing all baseline models. Comparative analysis revealed that the AUC-ROC of the multimodal model (0.8620) was significantly higher than that of models using only structured data (0.8166) or chest X-ray data alone (0.7479). This study demonstrates the value of CXRs in the prognosis of heart failure, showing that the combination of longitudinal CXRs with structured EHR data can significantly improve the accuracy of mortality prediction in heart failure. Feature importance analysis based on SHAP provides interpretable decision support, paving the way for potential clinical applications.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"427-440"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}