The international journal of cardiovascular imaging最新文献

{"title":"Do flow-gradient groups determined by MDCT predict outcomes: validating CT stroke volume.","authors":"Faisal Rahman, Pallavi Pandey, Ankur Pandey, Matthew J Czarny, Jelani Grant, Stefan L Zimmerman","doi":"10.1007/s10554-025-03378-x","DOIUrl":"https://doi.org/10.1007/s10554-025-03378-x","url":null,"abstract":"<p><strong>Background: </strong>Identifying severe aortic stenosis can be difficult especially among patients with low-flow states compared to normal flow. Non-invasive modalities can aid in the diagnosis for timely treatment.</p><p><strong>Methods: </strong>In this retrospective, single-center study of patients with aortic stenosis who underwent transcatheter aortic valve replacement (TAVR), we calculated stroke volume using CT blood pool based (CT-blp) analysis, echocardiogram and right heart catheterization (cath) performed before TAVR. We compared the performance of each modality in predicting 30-day and 1-year outcomes.</p><p><strong>Results: </strong>Three-hundred and forty-five patients were included with a median age of 84 (79-88) years and 52.8% females. CT-blp correlated more strongly (r = 0.60) with cath-derived stroke volume than echo (r = 0.37). After stratifying patients into groups based on flow and gradient using echo or CT-blp, there was no difference in mortality with either modality among the groups. However, the composite of mortality and hospital readmission was significantly higher in the low-flow low-gradient group (CT-blp 30-day OR 2.6, 95% CI 1.3-5.3, p < 0.01; 1-year OR 1.9, 95% CI 1.0-3.6; p = 0.04) compared to patients with normal flow high gradients when grouping was performed with CT-blp or echo.</p><p><strong>Conclusion: </strong>Using the CT performed on patients pre-TAVR, CT-blp can provide an estimation of stroke volume that correlates well with invasive evaluation. The stroke volume may be used to stratify patient populations being evaluated for TAVR into flow gradient groups when echo is limited and avoid invasive catheterization to help identify patients with low-flow, low-gradient aortic stenosis. Further studies with larger cohorts are required to confirm our findings.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ruptured aneurysm of the non-coronary sinus of Valsalva with detachment of the tricuspid valve annulus: an unusual complication of a rare cardiac anomaly.","authors":"Nicola Ciocca, Philipp Carl Rösslhuemer, Volkhard Göber, Martha Veit, Florian Schönhoff, Emrush Rexhaj","doi":"10.1007/s10554-025-03391-0","DOIUrl":"https://doi.org/10.1007/s10554-025-03391-0","url":null,"abstract":"<p><p>Sinus of Valsalva aneurysm is a rare cardiac anomaly, often associated with ventricular septal defects, aortic valve dysfunction, and frequently asymptomatic until rupture. Acute rupture typically occurs into the right ventricle and requires prompt surgical intervention. In this article, we describe the case of a 36-year-old female patient in good overall health who presented with ruptured sinus of Valsalva aneurysm complicated by detachment of the commissure between the septal and anterior cusps of the tricuspid valve, resulting in severe regurgitation. The patient underwent emergent cardiac surgery, which included repair of the non-coronary sinus and tricuspid valve.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143789457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advanced cardiac imaging modalities in U.S. heart transplant centers: availability and distribution.","authors":"Maria Alwan, Attila Feher, Mahmoud Al Rifai, Ahmed Sayed, Ahmad El Yaman, Asim Shaikh, Mouaz H Al-Mallah","doi":"10.1007/s10554-025-03389-8","DOIUrl":"https://doi.org/10.1007/s10554-025-03389-8","url":null,"abstract":"<p><strong>Purpose: </strong>This study evaluates the availability of advanced imaging modalities, including cardiac computed tomography (CCT), cardiac magnetic resonance (CMR), cardiac positron emission tomography (PET), and intravascular ultrasound (IVUS)/optical coherence tomography (OCT), at Medicare-approved heart transplant centers across the United States.</p><p><strong>Methods: </strong>We retrieved the list of Medicare-approved heart transplant centers and data on physicians billing for cardiac imaging procedures from the CMS website. Addresses of billing physicians were matched with those of heart transplant centers to determine the availability of imaging modalities at each center. Additionally, we calculated the number of available imaging modalities and the median volume of studies per center. Further, we mapped heart transplant centers along with their available modalities.</p><p><strong>Results: </strong>Of 129 Medicare-approved heart transplant centers, 90.7% offered CCT, 85.3% provided CMR, 74.4% had IVUS/OCT, and 55% offered cardiac PET. Only 39.5% of centers had all four modalities available. Geographic disparities were observed, with clustering of centers and modalities in the Northeast and West Coast and fewer centers in the Midwest.</p><p><strong>Conclusion: </strong>This study highlights disparities in the availability of advanced imaging modalities in heart transplant centers across the United States. While CCT and CMR are widely available, the availability of cardiac PET and IVUS/OCT remains limited.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143782328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Speckle-tracking echocardiography of left and right ventricle and acute cellular rejection in orthotropic heart transplantation: a systematic review and meta-analysis.","authors":"Eleni Xourgia, Kristina Brignoli, Olivier Linder, Alexandra-Maria Neagoe, Lukas Capek, Jolie Bruno, Eva Strickler, Adam Bakula, Maryam Pavlicek-Bahlo, Monika Fürholz, Christian Muster, Patrizia Malagutti, Michele Martinelli, Lukas Hunziker, Bruno Schnegg","doi":"10.1007/s10554-024-03297-3","DOIUrl":"10.1007/s10554-024-03297-3","url":null,"abstract":"<p><p>After a cardiac transplantation, the steering of immunosuppression requires an active search for acute cellular rejection (ACR). Surveillance with endomyocardial biopsy (EMB) is the gold standard. Given the costs and potential complications, there is growing interest in the use of non-invasive screening methods. Thus, we have conducted a systematic review and meta-analysis to evaluate the role of speckle-tracking echocardiography as a screening method for ACR. We searched PubMed (CENTRAL) and gray literature for studies presenting data on speckle tracking echocardiography in heart-transplant patients experiencing acute cellular rejection. The primary outcomes of the meta-analysis were left and right ventricular global longitudinal strain. We used random effects models for all our calculations. We pre-registered our meta-analysis with PROSPERO (CRD42024508654). By incorporating data from over 2000 biopsies included in 18 studies, we found that both left (LVGLS, MD -1.96, 95% CI -2.85 to -1.07, p < 0.0001), and right (RVGLS, MD -2.90, 95% CI -4.03 to -1.76, p < 0.00001) ventricular longitudinal strain were lower among patients without ACR. The change of LVGLS from baseline over time was also greater among patients experiencing ACR (MD -2.43, 95% CI -4.82 to -0.05, p = 0.045). Current data suggest that myocardial strain measured by speckle tracking echocardiography is affected in ACR and could potentially be used for early rejection detection as a rule-out strategy, leading to reduction of routine EMB in heart transplant follow-up.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"669-679"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142788325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Value of upfront coronary computed tomography angiography in patients with non-ST-segment elevation acute coronary syndrome.","authors":"Zhong-Fei Lu, Wei-Hua Yin, Bin Lu","doi":"10.1007/s10554-025-03360-7","DOIUrl":"10.1007/s10554-025-03360-7","url":null,"abstract":"<p><p>This study aimed to evaluate the diagnostic performance of coronary computed tomography angiography (CCTA) in ruling out coronary artery stenosis ≥ 70% across all segments and its role in providing preprocedural guidance for chronic total occlusion (CTO) management in patients with non-ST-segment elevation acute coronary syndrome (NSTE-ACS). This study was a post hoc analysis of a prospective, multicenter cohort comprising 347 patients with NSTE-ACS. All patients underwent CCTA immediately after being diagnosed with NSTE-ACS, followed by invasive coronary angiography (ICA) within 1 day. The diagnostic performance of CCTA in ruling out obstructive coronary stenosis was assessed using negative predictive value (NPV). Additionally, segments distal to CTO were analyzed to compare the detection capabilities of CCTA and ICA. The NPV of CCTA for ruling out coronary stenosis ≥ 70% was robust, ranging from 94.7 to 100.0% across the 18-segment model at the segment level, and 25.9% of patients had no significant stenosis and could have avoided unnecessary ICA based on CCTA findings. CCTA identified 71.0% of segments distal to CTO, significantly higher than ICA (48.8%, P < 0.001). 25.1% of patients had CTO, where CCTA provided valuable preprocedural guidance for revascularization. CCTA demonstrated high diagnostic accuracy in ruling out significant stenosis and provided critical information for CTO revascularization, highlighting its potential as a triaging and planning tool in NSTE-ACS.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"733-742"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143569308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A case of constrictive pericarditis with aortic insufficiency: the role of cardiac magnetic resonance imaging.","authors":"Juthipong Benjanuwattra, Nicholas Biondi, Jonathan D Feazell, Sara A Dressman, David M Harris","doi":"10.1007/s10554-025-03373-2","DOIUrl":"10.1007/s10554-025-03373-2","url":null,"abstract":"<p><p>Transthoracic echocardiography is recommended as a diagnostic test of choice for constrictive pericarditis. Nevertheless, several limitations exist. Hereby, we present the role of cardiac magnetic resonance imaging in a case of constrictive pericarditis with concurrent aortic insufficiency that masked the echocardiographic features of ventricular interdependence.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"793-798"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability of spectral Doppler in handheld ultrasonographic device.","authors":"Dominika Filipiak-Strzecka, Jarosław D Kasprzak, Piotr Lipiec","doi":"10.1007/s10554-025-03372-3","DOIUrl":"10.1007/s10554-025-03372-3","url":null,"abstract":"<p><p>To verify and validate the reliability of diastolic function parameters and valvular flow velocities acquired during the handheld ultrasound device (HUD) echocardiographic examination. Study population consisted of the consecutive patients referred for consultation due to dyspnea or impaired exercise tolerance. All patients underwent brief bedside echocardiographic screening with HUD. Within the next 24 h all patients underwent full echocardiographic examination (treated as reference). 105 patients (58 men, mean age 65 ± 14 years) were enrolled in the study. All correlations of HUD and standard echo derived measurements were high or very high. Bland-Altman plot analysis revealed the underestimation bias for mitral inflow velocities- early (E) and late (A), ), mitral annular peak early diastolic velocity (e') was not burdened with bias. The agreement between the major HFA-PEFF score parameters showed either substantial or almost perfect agreement, minor parameter- moderate agreement. The correlation of the measurements of maximum mitral velocity was high with no clinically relevant bias. Kappa coefficient showed very good agreement between HUD and reference echocardiography for detecting accelerated blood flow through the mitral valve (Kappa coefficient 0.83). The assessment of the aortic valve showed a very good correlation, with a slight underestimation bias of -0.17 m/sec (P <.001). Kappa coefficient showed good agreement between HUD and reference echocardiography for detecting accelerated blood flow (Kappa coefficient 0.74). HUD equipped with pulse and continuous wave Doppler modality enables reliable measurements of the parameters used during the left ventricle diastolic function assessment. Similarly, aortic and mitral peak jet velocities can be accurately measured using the mentioned devices.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"783-791"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bicuspid aortic valve imaging: one modality to rule them all?","authors":"Marco Guglielmo, Francesca Coraducci","doi":"10.1007/s10554-025-03385-y","DOIUrl":"10.1007/s10554-025-03385-y","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"645-646"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143766201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intramyocardial fatty infiltration lesion in sporadic inclusion body myositis: a case report.","authors":"Betim Redzepi, Marie Théaudin, Samir Bengueddache, Sofia Petropoulou-Natsou, Ambra Masi, David Rodrigues, Georgios Tzimas, Juerg Schwitter, Panagiotis Antiochos","doi":"10.1007/s10554-024-03271-z","DOIUrl":"10.1007/s10554-024-03271-z","url":null,"abstract":"<p><p>Sporadic inclusion body myositis (sIBM), the most common inflammatory muscle disorder in adults over 50 years, is often misdiagnosed due to its gradual onset and its common but unspecific muscle weakness in older adults. Diagnosis relies on clinical, radiological, and pathological features. Cardiac involvement is rare, prompting this case description and a comprehensive literature analysis. A 73-year-old woman diagnosed with sIBM in 2021 through muscle biopsy had been experiencing muscular symptoms since 2015. Her condition progressively worsened, affecting daily activities. Annual follow-ups revealed a moderate obstructive syndrome on respiratory testing, prompting a cardiac evaluation. Cardiac magnetic resonance (CMR) imaging identified intramyocardial lesions consistent with fatty infiltration, highlighting the interest of advanced imaging in sIBM management. Cardiac involvement in sIBM is presumed rare compared to other idiopathic inflammatory myopathies, though the exact frequency remains unclear. Early identification of heart alterations by CMR in sIBM can be prognostically valuable, guiding follow-up and interventions. However, literature on this subject is limited to small cohort studies and case reports describing complications. Given the slow progression of sIBM and the limited efficacy of current treatments, the discovery of myocardial lesions could warrant closer cardiological monitoring. Larger cohort studies are needed to explore potential new therapeutic approaches. Our case underscores the importance of CMR in detecting subtle cardiac manifestations in sIBM and illustrates the potential prognostic value of cardiac assessment in the management of sIBM.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"799-805"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142524031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Non-invasive derivation of instantaneous free-wave ratio from invasive coronary angiography using a new deep learning artificial intelligence model and comparison with human operators' performance.","authors":"Catarina Oliveira, Marta Vilela, João Silva Marques, Cláudia Jorge, Tiago Rodrigues, Ana Rita Francisco, Rita Marante de Oliveira, Beatriz Silva, João Lourenço Silva, Arlindo L Oliveira, Fausto J Pinto, Miguel Nobre Menezes","doi":"10.1007/s10554-025-03369-y","DOIUrl":"10.1007/s10554-025-03369-y","url":null,"abstract":"<p><p>Invasive coronary physiology is underused and carries risks/costs. Artificial Intelligence (AI) might enable non-invasive physiology from invasive coronary angiography (CAG), possibly outperforming humans, but has seldom been explored, especially for instantaneous wave-free Ratio (iFR). We aimed to develop binary iFR lesion classification AI models and compare them with human performance. single-center retrospective study of patients undergoing CAG and iFR. A validated encoder-decoder convolutional neural network (CNN) performed segmentation. Manual annotation of target vessel and pressure sensor location on a segmented telediastolic frame followed. Three AI models classified lesions as positive (≤ 0.89) or negative (> 0.89). Model 1 uses preprocessed vessel diameters with a transformer. Models 2/3 are EfficientNet-B5 CNNs using concatenated angiography and segmentation - Model 3 employs class-frequency-weighted Cross-Entropy Loss. Previous findings demonstrated Model 3's superiority for left anterior descending (LAD) and Model 1's for circumflex (Cx)/right coronary artery (RCA) - they were therefore unified into a vessel-based model. Ten-fold patient-level cross-validation enabled full sample training/testing. Three experienced operators performed binary iFR classification using single frames of raw/segmented images. Comparison metrics were accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV). Across 250 measurements, AI accuracy was 72%, PPV 48%, NPV 90%, sensitivity 77%, and specificity 71%. Human accuracy ranged from 54 to 74%. NPV was high for the Cx/RCA (AI: 96/98%; operators: 94/97%), but AI significantly outperformed humans in the LAD (78% vs. 60-64%). An AI model capable of binary iFR lesions classification mildly outperformed interventional cardiologists, supporting further validation studies.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"755-771"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}