The international journal of cardiovascular imaging最新文献

Disparities in diagnosis and outcomes in American patients with transthyretin cardiac amyloidosis. 美国转甲状腺素型心脏淀粉样变性患者的诊断和预后差异。

The international journal of cardiovascular imaging Pub Date : 2025-06-05 DOI: 10.1007/s10554-025-03436-4

Joyce L Ngouchet Nouhossi, Iva Minga, Teodora Szasz, Vien T Truong, Amber E Johnson, Edward Yang, Srisha Kotlo, Varun Subashchandran, Frank Medina, Karolina M Zareba, Akash Goyal, Orlando P Simonetti, Amit R Patel, Cristiane C Singulane, Jai Singh, Vidya Nadig, Shaimaa Fadl, Cory R Trankle, Nitasha Sarswat, Hena N Patel, Victor Mor-Avi, Bryan Smith, Jeremy A Slivnick

{"title":"Disparities in diagnosis and outcomes in American patients with transthyretin cardiac amyloidosis.","authors":"Joyce L Ngouchet Nouhossi, Iva Minga, Teodora Szasz, Vien T Truong, Amber E Johnson, Edward Yang, Srisha Kotlo, Varun Subashchandran, Frank Medina, Karolina M Zareba, Akash Goyal, Orlando P Simonetti, Amit R Patel, Cristiane C Singulane, Jai Singh, Vidya Nadig, Shaimaa Fadl, Cory R Trankle, Nitasha Sarswat, Hena N Patel, Victor Mor-Avi, Bryan Smith, Jeremy A Slivnick","doi":"10.1007/s10554-025-03436-4","DOIUrl":"https://doi.org/10.1007/s10554-025-03436-4","url":null,"abstract":"Although Afro-Caribbean (AC) race has been associated with worse outcomes in many cardiovascular diseases, its potential association with transthyretin cardiac amyloidosis (ATTR-CA) is less understood. We aimed to assess the relationship between race and serum biomarkers, adverse cardiac remodeling, and outcomes in AC vs white ATTR-CA patients. 114 AC and 117 white patients confirmed ATTR-CA who underwent cardiac magnetic resonance (CMR) exam were identified. The relationship between race and the primary endpoint-defined by all-cause mortality or heart failure hospitalization-was assessed using Cox regression analysis. ATTR disease stage was significantly higher at diagnosis in AC vs white patients (p < 0.0001). Left (p = 0.001) and right ventricular ejection fractions (p = 0.0002) were lower and extracellular volume (58% vs 50%) higher in AC vs white patients. At a median follow up time of 365 (IQR, 97-879) days, 44% of patients had experienced the primary endpoint. AC race was strongly associated with the primary endpoint compared with White patients (HR 2.83, 95% CI 1.92-4.23, p < 0.0001). AC patients were found to be at more advanced disease stages at the time of ATTR-CA diagnosis and experienced poor outcomes more frequently, highlighting the need for targeted strategies to address these health inequities.","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144236357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of contrast medium volume on myocardial extracellular volume measurement accuracy in first-generation photon-counting detector CT. 第一代光子计数检测器CT造影剂体积对心肌细胞外体积测量精度的影响。

The international journal of cardiovascular imaging Pub Date : 2025-06-05 DOI: 10.1007/s10554-025-03437-3

Takanori Kokawa, Satoshi Nakamura, Masafumi Takafuji, Akio Yamazaki, Hajime Sakuma, Kakuya Kitagawa

{"title":"Impact of contrast medium volume on myocardial extracellular volume measurement accuracy in first-generation photon-counting detector CT.","authors":"Takanori Kokawa, Satoshi Nakamura, Masafumi Takafuji, Akio Yamazaki, Hajime Sakuma, Kakuya Kitagawa","doi":"10.1007/s10554-025-03437-3","DOIUrl":"https://doi.org/10.1007/s10554-025-03437-3","url":null,"abstract":"Photon-counting detector CT (PCD-CT) holds promise for cardiac CT imaging, including the measurement of extracellular volume (ECV), due to its advanced imaging capabilities. The study aimed to compare the protocols with and without additional contrast medium after coronary CT angiography (CCTA) by evaluating (1) the stability of subtraction method-based ECV (ECVSUB) across various keV images and (2) the correlation and agreement of ECVSUB with iodine map-based ECV (ECVIOD). Forty patients with known or suspected coronary artery disease were divided into two groups. In Protocol A (n = 20), only the standard contrast dose for CCTA was administered, while in Protocol B (n = 20), additional contrast medium was given after CCTA. The difference between the largest and smallest ECVSUB among multiple keV images was defined as the variability of ECVSUB. Correlations and agreement between the methods were assessed using Pearson's correlation coefficient (r), intraclass correlation coefficient (ICC), and Bland-Altman analyses. The mean variability in ECVSUB was significantly higher in Protocol A (3.8 ± 2.1) compared to Protocol B (2.1 ± 0.9) (p = 0.008). In Protocol A, the correlation between ECVSUB and ECVIOD was poor (r = 0.43, p = 0.059) with a low ICC of 0.40. In this group, Bland-Altman analysis showed a mean difference of 3.7 and limits of agreement from -9.4 to 16.8. In Protocol B, a stronger correlation was observed (r = 0.74, p < 0.001) with an ICC of 0.68. In this group, the mean difference was 2.8 with narrower limits of agreement (-4.8 to 10.4). Additional contrast medium is essential for stable myocardial ECV measurements using PCD-CT.","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144228208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of image quality between photon-counting detector CT and energy-integrating detector coronary CT angiography in heart transplant patients. 光子计数检测器CT与能量积分检测器冠状动脉CT血管造影在心脏移植患者中的图像质量比较。

The international journal of cardiovascular imaging Pub Date : 2025-06-02 DOI: 10.1007/s10554-025-03433-7

Simran P Sharma, Ricardo P J Budde, Jan Willem Groen, Marcel L Dijkshoorn, Olivier C Manintveld, Alexander Hirsch

{"title":"Comparison of image quality between photon-counting detector CT and energy-integrating detector coronary CT angiography in heart transplant patients.","authors":"Simran P Sharma, Ricardo P J Budde, Jan Willem Groen, Marcel L Dijkshoorn, Olivier C Manintveld, Alexander Hirsch","doi":"10.1007/s10554-025-03433-7","DOIUrl":"https://doi.org/10.1007/s10554-025-03433-7","url":null,"abstract":"This study aims to compare the image quality between photon-counting detector computed tomography (PCD-CT) and energy-integrating CT (EID-CT) for coronary artery visualization post-heart transplant (HTx) patients, using a paired comparison within one patient. Consecutive HTx patients who underwent both 3rd generation dual source EID-CT and ultra-high-resolution PCD-CT scans as part of routine clinical care, with a maximum interval of two years between scans were included. Image quality was assessed subjectively using a 5-point Likert scale and quantitatively with the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR). Coronary segments were scored for presence, stenosis degree, presence of artifacts, and plaque composition. Thirty patients were included (mean age 50 ± 17 years; 21 (70%) men). The median interval between scans was 17[12-24] months. The median calcium score was 9[0-51] on the EID-CT scan and 25[0-92] on the PCD-CT. On the PCD-CT, 90% of coronary segments were rated very good or excellent compared to 71% on EID-CT (p < 0.001). Fewer segments were absent or non-evaluable due to size with PCD-CT compared to EID-CT (30% vs. 34%; p < 0.001). PCD-CT identified more mixed plaques (11% vs. 3%, p < 0.001). SNR and CNR were significantly higher on PCD-CT (22.1 ± 6.1 and 27.8 ± 6.8, p < 0.001) than on EID-CT (14.3 ± 3.4 and 16.9 ± 3.6, p < 0.001). The CT dose index volume was 6 [5-10] mGy on EID-CT and 19 [14-21] mGy on PCD-CT (p < 0.001). Ultra-high-resolution PCD-CT improves image quality compared to EID-CT in HTx patients. With superior SNR and CNR, and fewer non-evaluable segments, PCD-CT offers enhanced coronary artery visualization, though at the cost of an increased radiation dose.","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thoracic aortic calcifications on chest radiographs and incident major adverse limb events in cardiovascular disease patients. 心血管疾病患者胸片上的胸主动脉钙化与主要肢体不良事件的发生

The international journal of cardiovascular imaging Pub Date : 2025-06-02 DOI: 10.1007/s10554-025-03435-5

Netanja I Harlianto, Firdaus A A Mohamed Hoesein, Willem P T H Mali, Marjolein E Hol, Constantijn E V B Hazenberg, Joost A van Herwaarden, Wouter Foppen, Pim A de Jong

{"title":"Thoracic aortic calcifications on chest radiographs and incident major adverse limb events in cardiovascular disease patients.","authors":"Netanja I Harlianto, Firdaus A A Mohamed Hoesein, Willem P T H Mali, Marjolein E Hol, Constantijn E V B Hazenberg, Joost A van Herwaarden, Wouter Foppen, Pim A de Jong","doi":"10.1007/s10554-025-03435-5","DOIUrl":"https://doi.org/10.1007/s10554-025-03435-5","url":null,"abstract":"Thoracic aortic calcifications (TAC) are a common finding in medical imaging. We assessed the association between TAC on chest radiographs and major adverse limb events (MALE), other cardiovascular outcomes, and mortality in cardiovascular disease patients. A total of 4680 patients were included from the prospective Utrecht Cardiovascular Cohort-Second Manifestation of ARTerial disease cohort. TAC severity was classified based on chest radiographs by certified readers as mild, moderate, and severe. Multivariate cox proportional hazard models were utilized to assess associations between TAC and incident MALE defined as major amputation, peripheral revascularization or thrombolysis in the lower limb. Secondary endpoints included major adverse cardiovascular events (MACE: stroke, myocardial infarction, and vascular death), and all-cause mortality. A total of 4680 patients were included. TAC was present in 1789 (38%) patients. After a median follow-up of 11.8 years (interquartile range: 7.6-15.7 years), 426 MALE, 992 MACE, and 1387 deaths occurred. TAC presence was associated with incident MALE after adjustments, (hazard ratio (HR):2.14;95%CI:1.73-2.65) and this risk increased with TAC severity (HRmild: 1.97; 95%CI:1.51-2.57, HRmoderate: 2.04; 95%CI:1.56-2.68, and HRsevere: 2.71; 95%CI: 2.02-3.65). Moreover, TAC was associated with incident MACE (HR:1.22;95%CI:1.06-1.40), ischemic stroke (HR: 1.45; 95%CI: 1.11-1.91), and vascular death (HR: 1.35; 95%CI: 1.13-1.63). TAC was only associated with all-cause mortality (HR:1.34;95%CI:1.18-1.52) in patients who experienced a previous cardiovascular event. In cardiovascular disease patients, TAC on chest radiographs is associated with an increased risk for incident MALE. In addition, we found that TAC was associated with incident ischemic stroke, MACE and all-cause mortality.","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144210612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Disentangling ejection fraction from partial volume effects and blood flow autoregulation. 从部分体积效应和血流自动调节中分离射血分数。

The international journal of cardiovascular imaging Pub Date : 2025-06-01 DOI: 10.1007/s10554-025-03427-5

Nils P Johnson

引用次数: 0

Ruptured aneurysm of the non-coronary sinus of Valsalva with detachment of the tricuspid valve annulus: an unusual complication of a rare cardiac anomaly. Valsalva非冠状窦动脉瘤破裂伴三尖瓣环脱离：罕见心脏异常的罕见并发症。

The international journal of cardiovascular imaging Pub Date : 2025-06-01 Epub Date: 2025-04-04 DOI: 10.1007/s10554-025-03391-0

Nicola Ciocca, Philipp Carl Rösslhuemer, Volkhard Göber, Martha Veit, Florian Schönhoff, Emrush Rexhaj

引用次数: 0

Do flow-gradient groups determined by MDCT predict outcomes: validating CT stroke volume. 由多层螺旋CT确定的血流梯度组能预测结果吗？

The international journal of cardiovascular imaging Pub Date : 2025-06-01 Epub Date: 2025-04-09 DOI: 10.1007/s10554-025-03378-x

Faisal Rahman, Pallavi Pandey, Ankur Pandey, Matthew J Czarny, Jelani Grant, Stefan L Zimmerman

{"title":"Do flow-gradient groups determined by MDCT predict outcomes: validating CT stroke volume.","authors":"Faisal Rahman, Pallavi Pandey, Ankur Pandey, Matthew J Czarny, Jelani Grant, Stefan L Zimmerman","doi":"10.1007/s10554-025-03378-x","DOIUrl":"10.1007/s10554-025-03378-x","url":null,"abstract":"Background: Identifying severe aortic stenosis can be difficult especially among patients with low-flow states compared to normal flow. Non-invasive modalities can aid in the diagnosis for timely treatment.Methods: In this retrospective, single-center study of patients with aortic stenosis who underwent transcatheter aortic valve replacement (TAVR), we calculated stroke volume using CT blood pool based (CT-blp) analysis, echocardiogram and right heart catheterization (cath) performed before TAVR. We compared the performance of each modality in predicting 30-day and 1-year outcomes.Results: Three-hundred and forty-five patients were included with a median age of 84 (79-88) years and 52.8% females. CT-blp correlated more strongly (r = 0.60) with cath-derived stroke volume than echo (r = 0.37). After stratifying patients into groups based on flow and gradient using echo or CT-blp, there was no difference in mortality with either modality among the groups. However, the composite of mortality and hospital readmission was significantly higher in the low-flow low-gradient group (CT-blp 30-day OR 2.6, 95% CI 1.3-5.3, p < 0.01; 1-year OR 1.9, 95% CI 1.0-3.6; p = 0.04) compared to patients with normal flow high gradients when grouping was performed with CT-blp or echo.Conclusion: Using the CT performed on patients pre-TAVR, CT-blp can provide an estimation of stroke volume that correlates well with invasive evaluation. The stroke volume may be used to stratify patient populations being evaluated for TAVR into flow gradient groups when echo is limited and avoid invasive catheterization to help identify patients with low-flow, low-gradient aortic stenosis. Further studies with larger cohorts are required to confirm our findings.","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1051-1063"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143813228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Deep learning-based post hoc denoising for 3D volume-rendered cardiac CT in mitral valve prolapse. 基于深度学习的三维体渲染心脏CT二尖瓣脱垂的事后去噪。

The international journal of cardiovascular imaging Pub Date : 2025-06-01 Epub Date: 2025-04-23 DOI: 10.1007/s10554-025-03403-z

Tatsuya Nishii, Tomoro Morikawa, Hiroki Nakajima, Yasutoshi Ohta, Takuma Kobayashi, Kensuke Umehara, Junko Ota, Takashi Kakuta, Satsuki Fukushima, Tetsuya Fukuda

{"title":"Deep learning-based post hoc denoising for 3D volume-rendered cardiac CT in mitral valve prolapse.","authors":"Tatsuya Nishii, Tomoro Morikawa, Hiroki Nakajima, Yasutoshi Ohta, Takuma Kobayashi, Kensuke Umehara, Junko Ota, Takashi Kakuta, Satsuki Fukushima, Tetsuya Fukuda","doi":"10.1007/s10554-025-03403-z","DOIUrl":"10.1007/s10554-025-03403-z","url":null,"abstract":"We hypothesized that deep learning-based post hoc denoising could improve the quality of cardiac CT for the 3D volume-rendered (VR) imaging of mitral valve (MV) prolapse. We aimed to evaluate the quality of denoised 3D VR images for visualizing MV prolapse and assess their diagnostic performance and efficiency. We retrospectively reviewed the cardiac CTs of consecutive patients who underwent MV repair in 2023. The original images were iteratively reconstructed and denoised with a residual dense network. 3DVR images of the \"surgeon's view\" were created with blood chamber transparency to display the MV leaflets. We compared the 3DVR image quality between the original and denoised images with a 100-point scoring system. Diagnostic confidence for prolapse was evaluated across eight MV segments: A1-3, P1-3, and the anterior and posterior commissures. Surgical findings were used as the reference to assess diagnostic ability with the area under curve (AUC). The interpretation time for the denoised 3DVR images was compared with that for multiplanar reformat images. For fifty patients (median age 64 years, 30 males), denoising the 3DVR images significantly improved their image quality scores from 50 to 76 (P <.001). The AUC in identifying MV prolapse improved from 0.91 (95% CI 0.87-0.95) to 0.94 (95% CI 0.91-0.98) (P =.009). The denoised 3DVR images were interpreted five-times faster than the multiplanar reformat images (P <.001). Deep learning-based denoising enhanced the quality of 3DVR imaging of the MV, improving the performance and efficiency in detecting MV prolapse on cardiac CT.","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1161-1172"},"PeriodicalIF":0.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ruptured coronary aneurysm with fatal bleeding: a tricky differential diagnosis. 冠状动脉瘤破裂伴致命出血：一个棘手的鉴别诊断。

The international journal of cardiovascular imaging Pub Date : 2025-06-01 Epub Date: 2025-04-22 DOI: 10.1007/s10554-025-03402-0

Pietro G Lacaita, Gudrun M Feuchtner

引用次数: 0

Correction: Beyond hypertrophic cardiomyopathy: unmasking alternative causes of LVOT obstruction on CMR. 更正：除了肥厚性心肌病：在CMR上揭示LVOT阻塞的其他原因。

The international journal of cardiovascular imaging Pub Date : 2025-06-01 DOI: 10.1007/s10554-025-03399-6

Tanushree Banerjee, Avanti Gulhane, Aarohi Bhatt, Mathew Cham

引用次数: 0