The international journal of cardiovascular imaging最新文献

筛选
英文 中文
Clinical utility and impact of myocardial viability imaging with F-18 FDG positron emission tomography to predict left ventricular function improvement following revascularization in ischemic heart disease : a single center retrospective study. F-18 FDG正电子发射断层显像对缺血性心脏病血运重建术后左心室功能改善的临床应用和影响:一项单中心回顾性研究
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-17 DOI: 10.1007/s10554-026-03843-1
Muhammad Ahmad Qureshi, Mariam Saleem, Karthikeyan Ananthasubramaniam
{"title":"Clinical utility and impact of myocardial viability imaging with F-18 FDG positron emission tomography to predict left ventricular function improvement following revascularization in ischemic heart disease : a single center retrospective study.","authors":"Muhammad Ahmad Qureshi, Mariam Saleem, Karthikeyan Ananthasubramaniam","doi":"10.1007/s10554-026-03843-1","DOIUrl":"https://doi.org/10.1007/s10554-026-03843-1","url":null,"abstract":"<p><p>Recent studies have questioned the benefit of myocardial viability identification and its clinical impact on revascularization decisions. We aimed to evaluate whether F-18 fluorodeoxyglucose (F-18 FDG)-positron emission tomography (PET) influences real-world revascularization decisions and whether PET-defined viability helps predict improvement in ejection fraction (LVEF). We conducted a retrospective chart review of Rubidium-82 (Rb-82)/F-18 FDG PET ischemia and viability studies performed from 2020 to 2024 at our institution. Baseline characteristics including comorbidities, ejection fraction (EF) at 3 months and 1 year and PET study results were evaluated. Among patients with viability, a linear mixed-effects model adjusted for baseline EF was performed to assess temporal changes and treatment strategy interaction. One hundred and eleven patients underwent rest-stress Rb-82 PET with F-18 FDG PET imaging, of whom 99 received FDG for myocardial viability assessment. Among these patients, 65 (65.6%) demonstrated ischemic viable myocardium, while 31 (31.3%) had non-viable myocardium. Viability-positive patients were more likely to undergo revascularization (57% (n = 37) vs. 36% (n = 28) received medical therapy only). At 3-month follow-up, both revascularization and medical therapy were associated with significant improvement in LVEF among viability-positive patients. In contrast, viability-negative patients did not demonstrate significant EF improvement. Among viability-positive patients with both 3-month and 1- year EF measurements (N = 28), linear mixed-effects model adjusted for baseline EF revealed that baseline EF was a strong independent predictor of follow-up EF (p < 0.0001). From 3 months to 1 year, the revascularization group demonstrated a significant increase in EF (+ 4.28%, p = 0.014), whereas the medical therapy group showed a non-significant change (+ 1.40%, p = 0.53). However, the overall EF improvement did not differ significantly between groups after adjustment (p = 0.30). EF changes in viability-negative patients remained non-significant over time. Symptomatic improvement was documented in 55.3% of viability-positive patients. Our single-center experience shows that FDG-PET viability test continues to guide management and decision making regarding revascularization and can predict functional recovery and symptomatic improvement.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149217791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cardiac CT demonstration of perivalvular extension in aortic valve infective endocarditis. 主动脉瓣感染性心内膜炎的心脏CT表现。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-17 DOI: 10.1007/s10554-026-03842-2
Anish Goel, Arzu Canan
{"title":"Cardiac CT demonstration of perivalvular extension in aortic valve infective endocarditis.","authors":"Anish Goel, Arzu Canan","doi":"10.1007/s10554-026-03842-2","DOIUrl":"https://doi.org/10.1007/s10554-026-03842-2","url":null,"abstract":"<p><p>Delayed-phase cardiac CT depicts perivalvular abscess, demonstrating its adjunctive role to echocardiography in endocarditis evaluation.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149217813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Papillary fibroelastoma of the coumadin ridge as an unusual cause of recurrent ischemic stroke: a case report. 香豆素脊乳头状纤维弹性瘤是复发性缺血性脑卒中的罕见病因:1例报告。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-12 DOI: 10.1007/s10554-026-03840-4
Alexander Suchodolski, Agata Ogrodzka, Roksana Kemona-Kałwa, Rafał Skowronek, Jerzy Nożyński, Roch Pakuła, Karol Miszalski-Jamka, Tomasz Niklewski, Marek Waligóra, Zuzanna Jackowska, Jan Głowacki, Grzegorz Hirnle, Mariola Szulik
{"title":"Papillary fibroelastoma of the coumadin ridge as an unusual cause of recurrent ischemic stroke: a case report.","authors":"Alexander Suchodolski, Agata Ogrodzka, Roksana Kemona-Kałwa, Rafał Skowronek, Jerzy Nożyński, Roch Pakuła, Karol Miszalski-Jamka, Tomasz Niklewski, Marek Waligóra, Zuzanna Jackowska, Jan Głowacki, Grzegorz Hirnle, Mariola Szulik","doi":"10.1007/s10554-026-03840-4","DOIUrl":"https://doi.org/10.1007/s10554-026-03840-4","url":null,"abstract":"<p><p>Cardiac papillary fibroelastoma (PFE) is a rare benign endocardial tumor with significant embolic potential despite its non-malignant histology. We report the case of a 51-year-old woman with palpitations and a history of ischemic stroke involving the left medulla oblongata, accompanied by multiple posterior fossa infarcts. Extensive thrombophilic and autoimmune investigations were negative, and a patent foramen ovale was excluded. Multimodal cardiac imaging, including transesophageal echocardiography (TEE) and cardiac magnetic resonance imaging (CMR), identified a highly mobile pedunculated mass attached to the coumadin ridge near the left atrial appendage ostium. Differential diagnosis included thrombus, myxoma, and PFE. The lesion was successfully removed by surgical excision, and histopathological examination confirmed PFE. This case highlights the coumadin ridge as an exceptionally rare site of PFE attachment and a potential source of recurrent cardioembolism. TEE and CMR are crucial for diagnosis, while surgical resection provides definitive treatment.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149171614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventricular septal thickness for cardiomyopathic phenotype enrichment in patients with established left ventricular hypertrophy. 左室肥厚患者心肌病表型富集的室间隔厚度。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-12 DOI: 10.1007/s10554-026-03839-x
Wei-Ting Wang, Hui Chen, Wen-Chung Yu
{"title":"Interventricular septal thickness for cardiomyopathic phenotype enrichment in patients with established left ventricular hypertrophy.","authors":"Wei-Ting Wang, Hui Chen, Wen-Chung Yu","doi":"10.1007/s10554-026-03839-x","DOIUrl":"https://doi.org/10.1007/s10554-026-03839-x","url":null,"abstract":"<p><p>We evaluated whether interventricular septal thickness in diastole (IVSd) ≥ 15 mm enriches cardiomyopathic phenotypes among adults with established left ventricular hypertrophy (LVH) and whether broader clinical-echocardiographic features improve triage. We studied 1,127 adults undergoing echocardiography from 2017 to 2019 who met established LVH criteria (sex-specific left ventricular mass index elevation and both IVSd and posterior wall thickness ≥ 13 mm). The primary phenotype was hypertrophic cardiomyopathy, Fabry disease, or amyloidosis. The composite phenotype occurred in 108 patients (9.6%) and was more frequent with IVSd ≥ 15 mm than 13.0-14.9 mm (16.2% vs. 3.6%, p < 0.001). After adjustment, IVSd ≥ 15 mm remained associated with the composite phenotype (odds ratio 2.38, 95% CI 1.35-4.20), with a graded association per 1-mm increase (odds ratio 1.50, 95% CI 1.33-1.70). At 15 mm, sensitivity, specificity, positive predictive value, and negative predictive value were 80.6%, 55.7%, 16.2%, and 96.4%; at 18 mm, case-finding yield increased to 41.7% but 58 of 108 cases were missed. A five-variable model improved discrimination over IVSd alone (area under the curve [AUC] 0.839 vs. 0.787; ΔAUC 0.052; p = 0.007; derivation AUC 0.857, temporal validation AUC 0.788), whereas adding binary IVSd ≥ 15 mm to conventional clinical-echocardiographic variables yielded minimal incremental discrimination (ΔAUC 0.003) and minimal additional net benefit. In established LVH, IVSd ≥ 15 mm identifies cardiomyopathic enrichment, with the composite association driven predominantly by hypertrophic cardiomyopathy, but is best used as a prompt for etiologic review rather than a diagnostic rule. A compact five-variable model may support triage.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of visual estimation of coronary artery calcifications on low-dose CT from oncologic FDG PET/CT. 肿瘤FDG PET/CT低剂量CT视觉估计冠状动脉钙化的准确性。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-12 DOI: 10.1007/s10554-026-03825-3
Florian Enderlin, Antonio G Gennari, Stephan Skawran, Thomas Sartoretti, Alexia Rossi, Thierry Schoeb, Alexander Maurer, Moritz Schwyzer, Joan E Walter, Martin W Huellner, Catherine Gebhard, Michael Messerli
{"title":"Accuracy of visual estimation of coronary artery calcifications on low-dose CT from oncologic FDG PET/CT.","authors":"Florian Enderlin, Antonio G Gennari, Stephan Skawran, Thomas Sartoretti, Alexia Rossi, Thierry Schoeb, Alexander Maurer, Moritz Schwyzer, Joan E Walter, Martin W Huellner, Catherine Gebhard, Michael Messerli","doi":"10.1007/s10554-026-03825-3","DOIUrl":"https://doi.org/10.1007/s10554-026-03825-3","url":null,"abstract":"<p><p>To evaluate the feasibility and accuracy of visual ordinal coronary artery calcium (CAC) scoring on low-dose, non-gated CT scans acquired as part of oncologic PET/CT, using CAC scoring from ECG-gated non-contrast cardiac CT as the reference standard. 210 oncological patients who underwent both PET/CT and single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) with ECG-gated non-contrast cardiac CT within 6 months were retrospectively included. Four independent readers graded image quality and assessed CAC burden using a visual ordinal scoring system (scores ranging from 0 to 12) on non-gated CT images from PET/CT. CAC scores as well as information on presence of myocardial ischemia and/or scars were recorded from the dedicated cardiac diagnostic workup and were used for comparison. Image quality was considered diagnostic in 99.6% of scans. Interreader agreement of ordinal scores was excellent among all four readers (Krippendorff's alpha = 0.95). Non-gated CT demonstrated favorable diagnostic performance for detecting CAC per-patient, with a sensitivity/specificity/positive predictive value/negative predictive value of 92.2%/95%/99.3%/62.1%. Ordinal scores showed a strong correlation with quantitative reference standard CAC scores (Spearman's rho = 0.9, p < 0.001). Receiver operating characteristic (ROC) analysis indicated that ordinal scores effectively differentiated patients based on reference standard CAC score cutoffs of 100, 400, and 1000, with AUC values of 0.96, 0.92, and 0.95, respectively. Additionally, using ordinal scores, ROC analysis yielded an AUC of 0.7 for differentiating patients with and without ischemia/scars. Visual ordinal scoring of CAC burden on low-dose non-gated CT of oncologic PET/CT scans is accurate, effective and strongly correlates with reference standard measurements. The lower negative predictive value indicates that (mild) coronary calcifications are occasionally underestimated.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coronary artery imaging in Kawasaki disease: recent updates in imaging techniques and clinical indications. 川崎病的冠状动脉影像学:影像学技术和临床适应症的最新进展
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-12 DOI: 10.1007/s10554-026-03836-0
Karnkawin Patharateeranart, Hyun Woo Goo, Akiyuki Kotoku, Abdul Latiff Haifa, Lingyi Wen
{"title":"Coronary artery imaging in Kawasaki disease: recent updates in imaging techniques and clinical indications.","authors":"Karnkawin Patharateeranart, Hyun Woo Goo, Akiyuki Kotoku, Abdul Latiff Haifa, Lingyi Wen","doi":"10.1007/s10554-026-03836-0","DOIUrl":"https://doi.org/10.1007/s10554-026-03836-0","url":null,"abstract":"<p><p>Coronary artery involvement in Kawasaki disease should be evaluated throughout all disease stages. Generally, multimodality imaging is necessary for both the acute and chronic phases of coronary artery abnormalities. This review summarizes current clinical indications and recent technical advances in coronary artery imaging in Kawasaki disease with an emphasis on the roles of computed tomography and magnetic resonance imaging. Echocardiography remains the first-line modality in all disease stages for evaluating coronary artery lesions and ventricular function. Recent technical developments in coronary computed tomography angiography can provide the accurate diagnosis of coronary artery lesions including stenosis and thrombus at substantially reduced radiation dose, supporting its selective use in serial follow-up. Cardiac magnetic resonance imaging offers the comprehensive evaluation of inducible myocardial ischemia, ventricular function, inflammation, and fibrosis. Invasive catheter angiography is reserved for complex or interventional cases. This review also addresses technical considerations and potential pitfalls for each imaging modality. Continued technical developments and their optimization with standardized imaging protocols and reports are expected to enhance diagnostic precision and eventually improve clinical outcomes in children with Kawasaki disease.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Molecular phenotyping of atrial remodeling in atrial fibrillation using 18F-FDG and 18F-FAPI PET. 利用18F-FDG和18F-FAPI PET对房颤的心房重构进行分子表型分析。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-05 DOI: 10.1007/s10554-026-03838-y
Shi-Da Duan, Lina Li, Bi-Xi Chen, Min-Fu Yang
{"title":"Molecular phenotyping of atrial remodeling in atrial fibrillation using <sup>18</sup>F-FDG and <sup>18</sup>F-FAPI PET.","authors":"Shi-Da Duan, Lina Li, Bi-Xi Chen, Min-Fu Yang","doi":"10.1007/s10554-026-03838-y","DOIUrl":"https://doi.org/10.1007/s10554-026-03838-y","url":null,"abstract":"<p><p>Atrial remodeling in atrial fibrillation (AF) involves multiple biological processes, including metabolic alterations, inflammation-related metabolic activity, and fibroblast activation, which can be assessed non-invasively with <sup>18</sup>F-fluorodeoxyglucose (FDG) and fibroblast activation protein inhibitors (FAPI) PET, respectively. We aimed to characterize and compare the atrial uptake patterns of these two tracers in patients with AF. In this post hoc cardinality-matched analysis of two prospective PET/CT cohorts, 90 patients with AF were included (45 imaged with ¹⁸F-FDG and 45 with ¹⁸F-FAPI). Left atrial volume index (LAVI) was measured using the echocardiographic ellipsoid method. The prevalence, intensity, and spatial distribution of atrial tracer uptake were compared between tracers, and clinical correlates of abnormal uptake were assessed using univariable analyses and logistic regression. ¹⁸F-FAPI showed a higher left atrial (LA) target-to-background ratio than ¹⁸F-FDG (P = 0.007). Abnormal uptake was more frequent with ¹⁸F-FDG in the left atrial appendage (LAA; 83.3% vs. 23.1%, P < 0.001), and more frequent with ¹⁸F-FAPI in the LA anterior wall (84.6% vs. 38.9%, P = 0.002) and LA roof (69.2% vs. 33.3%, P = 0.019). These differences persisted in persistent AF (PsAF); in paroxysmal AF, only the higher LAA ¹⁸F-FDG uptake remained (P = 0.015). Abnormal right atrial ¹⁸F-FDG uptake was associated with PsAF (P = 0.010), whereas abnormal LA ¹⁸F-FAPI uptake was associated with higher LAVI (P = 0.021) and lower low-density lipoprotein cholesterol (P = 0.006). ¹⁸F-FDG and ¹⁸F-FAPI PET demonstrated spatially divergent atrial uptake patterns in AF, suggesting cohort-level complementary information on metabolically active atrial remodeling and activated fibroblast-associated remodeling. This complementarity requires within-patient validation.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149121374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: Prevalence of impaired flow-mediated epicardial vasodilation among different types of coronary flow regulation. 致编辑的信:在不同类型的冠状动脉血流调节中,血流介导的心外膜血管舒张受损的患病率。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-01 Epub Date: 2026-06-24 DOI: 10.1007/s10554-026-03763-0
Syed Tawassul Hassan, Syeda Lyba Onaiz
{"title":"Letter to the Editor: Prevalence of impaired flow-mediated epicardial vasodilation among different types of coronary flow regulation.","authors":"Syed Tawassul Hassan, Syeda Lyba Onaiz","doi":"10.1007/s10554-026-03763-0","DOIUrl":"10.1007/s10554-026-03763-0","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"2033-2034"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148311136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Feasibility of 12-lead ECG reconstruction at rest and during adenosine stress perfusion inside a 3-Tesla MR scanner. 3特斯拉磁共振扫描仪内静息和腺苷应激灌注时12导联心电图重建的可行性。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-01 Epub Date: 2026-07-21 DOI: 10.1007/s10554-026-03772-z
Debbie Falconer, Maroua Mehri, Mohammed Bhiri, Matthew Webber, Isabelle Whitmore, Emma Martin, Lorena Topala, Giovanni Vagliani, Franca Morselli, Haytham Shah, Swapnanil De, Thomas A Treibel, Michele Orini, Nish Chaturvedi, Iain Pierce, Peter Kellman, Pier D Lambiase, James C Moon, Alun D Hughes, Freddy Odille, Guillaume Calmon, Gabriella Captur
{"title":"Feasibility of 12-lead ECG reconstruction at rest and during adenosine stress perfusion inside a 3-Tesla MR scanner.","authors":"Debbie Falconer, Maroua Mehri, Mohammed Bhiri, Matthew Webber, Isabelle Whitmore, Emma Martin, Lorena Topala, Giovanni Vagliani, Franca Morselli, Haytham Shah, Swapnanil De, Thomas A Treibel, Michele Orini, Nish Chaturvedi, Iain Pierce, Peter Kellman, Pier D Lambiase, James C Moon, Alun D Hughes, Freddy Odille, Guillaume Calmon, Gabriella Captur","doi":"10.1007/s10554-026-03772-z","DOIUrl":"10.1007/s10554-026-03772-z","url":null,"abstract":"<p><p>Background Electrocardiographic (ECG) devices in magnetic resonance (MR) scanners have a narrow bandwidth and suffer from signal distortion, preventing measurement of QRS/ QT durations, or detection of ST/ T-wave changes during ischaemia. We integrated an external device with novel post-processing software into a 3 Tesla (T) scanner to assess feasibility and accuracy for reconstructing 12-lead ECGs prior to and during adenosine infusion. Methods Reference 12-lead ECGs were first recorded outside the MR-environment. Using three MR-safe electrode patches, in-bore ECGs were then recorded prior to and during adenosine infusion. Post-processing removed artefacts and 12-lead ECGs were reconstructed from the raw signal using a subject-specific matrix. In-bore and reference ECGs were compared using Pearson's correlation coefficient on the PQRST waveform and by manual measurements of QRS and QT durations. Adenosine-induced ischaemic changes were compared with corresponding territories on stress perfusion maps. Results In 26 participants (70.8 ± 13.0 years; 34.6% female), in-bore ECGs were recorded without additional scan time. Reconstruction took < 2 min per participant. In-bore and reference ECGs were strongly correlated (r = 0.81, interquartile range 0.72-0.88), and mean differences in QRS and QT durations were small (-12.5 ms [95% limits of agreement - 42.5, 17.5 ms], and - 5.5 ms [-54.6, 43.6 ms] respectively). Ischaemic ECG changes during adenosine predicted stress myocardial blood flow (MBF) < 1.75 ml/g/min with sensitivity 91.7% (95% confidence interval 66.7, 100.0), specificity 59.3% (39.6, 77.6), positive predictive value (PPV) 33.3% (11.4, 57.7), negative predictive value (NPV) 97.0% (90.0, 100.0) and area under curve 0.74 (0.61, 0.86). Conclusion In this proof-of-concept study, in-bore ECGs correlated closely with reference ECGs. In-bore ECGs during stress perfusion have high specificity and NPV, but low sensitivity and PPV for predicting stress MBF < 1.5 ml/g/min. This may hold value for improving R-peak detection, patient monitoring and stress perfusion map interpretation.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1983-1998"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13646000/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148537902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A simplified geometric CMR method for reproducible quantification of left ventricular thrombus volume : Left Ventricular thrombus: a standardized measurement method. 一种简化的几何CMR方法可重复定量左室血栓体积:左室血栓:一种标准化的测量方法。
IF 1.5
The international journal of cardiovascular imaging Pub Date : 2026-10-01 Epub Date: 2026-06-15 DOI: 10.1007/s10554-026-03752-3
Antonin Fuzeau, Denis Angoulvant, Julien Pucheux, Nicolas Cazeneuve, Claire Bouleti, Loïc Biere, Didier Bresson, Ahmad Hayek, Charles De Bourguignon, Cyrille Bergerot, Naoual El Jonhy, Simon Leboube, Marine Tortigue, Benoit Lattuca, François Roubille, Nathan Mewton, Pierre Croisille
{"title":"A simplified geometric CMR method for reproducible quantification of left ventricular thrombus volume : Left Ventricular thrombus: a standardized measurement method.","authors":"Antonin Fuzeau, Denis Angoulvant, Julien Pucheux, Nicolas Cazeneuve, Claire Bouleti, Loïc Biere, Didier Bresson, Ahmad Hayek, Charles De Bourguignon, Cyrille Bergerot, Naoual El Jonhy, Simon Leboube, Marine Tortigue, Benoit Lattuca, François Roubille, Nathan Mewton, Pierre Croisille","doi":"10.1007/s10554-026-03752-3","DOIUrl":"10.1007/s10554-026-03752-3","url":null,"abstract":"<p><p>Left ventricular thrombus (LVT) is a frequent complication after myocardial infarction and is associated with increased risk of systemic embolism and adverse cardiovascular outcomes. However, the relationship between thrombus characteristics and its clinical evolution remains poorly understood, partly due to the lack of standardized and reproducible measurement methods. This study evaluated the feasibility and reproducibility of a simplified geometric CMR approach for standardized LVT volume assessment. This post-hoc analysis included patients from the COVERT-MI trial who underwent cardiac magnetic resonance (CMR) imaging 5 days after reperfusion for ST-segment elevation myocardial infarction. LVT volume was estimated using a simplified geometric method based on three orthogonal measurements (ABC/2 formula). Thrombus morphology, surface area, and insertion circumference were also assessed. Inter- and intra-reader reproducibility were evaluated using Bland-Altman analysis and Cohen's kappa coefficients. Associations with thrombus persistence at 3 months and clinical outcomes at 1 year were explored as secondary analyses. Among 161 patients who underwent baseline CMR, 25 (15.5%) had LVT. The mean estimated thrombus volume was 1.03 ± 1.09 cm³. At 3 months, thrombus regression occurred in 80% of patients. The ABC/2 method showed high reproducibility. Inter-observer reproducibility demonstrated a bias of 0.07 cm³, whereas intra-observer reproducibility showed a bias of 0.03 cm³. Inter-observer correlation was high (r = 0.86, SEE = 0.51 cm³), while intra-observer correlation was excellent (r = 0.99, SEE = 0.15 cm³). Accounting for thrombus shape had minimal impact on volume estimation (mean difference 0.035 cm³). No thrombus characteristic was significantly associated with thrombus persistence, and no cardioembolic events occurred during the 1-year follow-up. A simplified geometric CMR approach based on the ABC/2 formula provides a feasible and highly reproducible framework for estimating LVT volume. Further studies in larger cohorts are needed to determine the clinical and prognostic relevance of quantitative thrombus assessment.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"1869-1880"},"PeriodicalIF":1.5,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13645997/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148255301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信
小红书