The international journal of cardiovascular imaging最新文献

{"title":"Predicting the need for calcium modification techniques using computed tomography coronary angiography.","authors":"David Murphy, Benjamin Hudson, Stephen Lyen, Robert Lowe, Kevin Carson, Sri Raveen Kandan, Daniel McKenzie, Ali Khavandi, Jonathan Carl Luis Rodrigues","doi":"10.1007/s10554-025-03371-4","DOIUrl":"10.1007/s10554-025-03371-4","url":null,"abstract":"<p><p>Calcified coronary arteries pose a challenge to percutaneous coronary intervention (PCI). Calcium modification techniques (CMTs) increase procedural length, complexity and risk. Computed tomography coronary angiography (CTCA) is well suited to calcium identification and quantification and may offer valuable pre-procedural information. We hypothesised that CTCA could predict cases where CMT would be required during PCI. A single centre retrospective review (2021/2022) of consecutive patients who underwent PCI with a preceding CTCA demonstrating a calcified lesion in a major epicardial vessel. Blinded to the PCI strategy CTCA images were re-reviewed and calcium thickness, length, density and circumferential arc quantified. Receiver operating characteristic (ROC) curve for CMT defined optimum cut-off values. Calcium density (> 1000 HU) and calcific arc (> 180°) were proposed as a calcium planning score (CPS_CTCA), with 1 point assigned per criteria met. 76 PCI procedures were included (72 patients). CMT was used in 53% at the discretion of the operator. Calcific arc, density, length and thickness had an area under the curve (AUC) of 0.74, 0.7, 0.67 and 0.63 respectively. There was a step-wise increase in the proportion of cases requiring CMT with increasing CPS_CTCA. 0 vs. 1 point; OR 9 (1.1-82, p =.04), RR 5 (0.8-36, p =.09), 1 vs. 2 points; OR 3.2 (1.1-9.3, p =.03), RR 1.6 (1-2.3, p =.04), 0 vs. 2 points; OR 30 (3.3-272, p =.003), RR of 8 (1.3-54, p =.03). The incorporation of CTCA measured calcium density > 1000 HU and calcium arc > 180° into a calcium planning score may help with predicting the need for CMT at the time of PCI.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"773-781"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143598686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The prognostic value of preoperative CAD-RADS classification in patients undergoing isolated aortic valve surgery.","authors":"Kitae Kim, Byeong A Yoo, Hyun Jung Koo, Hong Rae Kim, Ho Jin Kim, Jae Suk Yoo, Joon Bum Kim, Cheol Hyun Chung, Sung-Ho Jung","doi":"10.1007/s10554-025-03358-1","DOIUrl":"10.1007/s10554-025-03358-1","url":null,"abstract":"<p><p>To investigate the association between preoperative coronary artery disease (CAD) severity, as classified by the Coronary Artery Disease Reporting and Data System (CAD-RADS), and clinical outcomes in patients undergoing isolated aortic valve replacement (AVR). A total of 897 patients (452 women; mean age, 66.1 ± 9.3 years) who underwent isolated AVR and preoperative coronary computed tomography angiography (CCTA) between 2004 and 2022 were stratified by the CAD-RADS score. The outcomes of interest were all-cause death and major adverse cardiac and cerebrovascular events (MACCE). The CAD-RADS score was 0 in 290 (32%) patients, 1 in 208 (23%), 2 in 255 (29%), 3 in 82 (9%), and 4 in 62 (7%) patients. The rates of all-cause death and MACCE tended to increase in parallel with CAD-RADS score (4%, 10.5%, 8.2%, 18.2%, 28.1% at 5 years and 14.4%, 15.1%, 16.7%, 26.9%, 38.4% at 5 years, both P < 0.001). CAD-RADS score ≥ 3 was associated with a higher risk of all-cause death (HR 2.44, 95% CI: 1.52-3.93) and MACCE (HR 1.79, 95% CI: 1.27-2.52) after adjusting for potential confounders. Notably, patients with CAD-RADS ≥ 3 who received medical therapy in addition to coronary angiography (CAG) improved overall survival compared to those who did not undergo CAG. Preoperative CCTA with CAD-RADS assessment would be useful for screening concomitant CAD and predicting long-term clinical outcomes including all-cause death and MACCE in patients undergoing isolated AVR. For patients with CAD-RADS ≥ 3, it is essential to implement medicinal therapy or intervention along with CAG.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"709-720"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of sampling rate during dynamic myocardial CT perfusion on coronary flow reserve and ischemia analysis.","authors":"Nobuo Tomizawa, Hiromi Ozu, Satoru Kamio, Shinichiro Fujimoto, Yui O Nozaki, Ruiheng Fan, Yuko O Kawaguchi, Kazuhisa Takamura, Makoto Hiki, Tadao Aikawa, Satoshi Kadowaki, Fuki Ikeda, Kanako K Kumamaru, Hirotaka Watada, Tohru Minamino, Shigeki Aoki","doi":"10.1007/s10554-025-03361-6","DOIUrl":"10.1007/s10554-025-03361-6","url":null,"abstract":"<p><p>Radiation dose is a major concern in dynamic myocardial CT perfusion scan. The purpose of this study was to investigate the effect of reducing the sampling rate on quantitative and semi-quantitative values. This single-center prospective study included 45 patients with type 2 diabetes mellitus (mean age, 58 ± 10 years [SD]; 30 men). Stress and rest dynamic CT perfusion scans were performed every heartbeat for 25 s. Coronary flow reserve (CFR) was calculated as the ratio of stress to rest myocardial blood flow. The summed difference score (SDS) was evaluated using stress and rest myocardial blood flow. CFR and SDS values were compared using the original dataset (1RR) and datasets with reduced sampling rates of 2 and 3 RR intervals (2RR and 3RR). Simulated effective doses were also compared. The mean CFR using the 1RR dataset was 5.89 ± 2.53, unchanged using the 2RR dataset (5.67 ± 2.42, p = 0.08) and decreased to 5.47 ± 2.45 (p = 0.001) using the 3RR dataset. The median SDS (interquartile range) using the 1RR, 2RR and 3RR datasets were 0 (0, 5.75), 0.5 (0, 7) and 0 (0, 6), respectively, with no difference (p > 0.05). The effective doses simulated using the 2RR and 3RR data were 6.7 ± 1.4 mSv and 5.8 ± 1.3 mSv, respectively, significantly lower than the original dose (9.2 ± 1.8 mSv, p < 0.001). A sampling rate of 2RR might be feasible for both semi-quantitative and quantitative evaluation in dynamic myocardial CT perfusion exams.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"743-753"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143485216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Triple threat endocarditis: a perfect storm of severe aortic regurgitation complicated by pseudoaneurysm, gerbode defect, and right atrial vegetation\".","authors":"Chelsea Meloche, Srikanth Koneru, Luba Frank","doi":"10.1007/s10554-025-03349-2","DOIUrl":"10.1007/s10554-025-03349-2","url":null,"abstract":"<p><p>Infective endocarditis (IE) remains a life-threatening condition. Perivalvular complications, such as pseudoaneurysms and intracardiac fistulae are life-threatening if untreated (Delgado in Eur Heart J 44:3948-4042, 2023). Multimodality imaging provides key information to assess and guide management of local IE complications (Delgado in Eur Heart J 44:3948-4042, 2023; Hubers et al. in Mayo Clin Proc 95:982-997, 2020).</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"809-810"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143722905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnosis of bicuspid aortic valves: CT vs. TTE.","authors":"Amy Sylivris, Zhao Feng Liu, James Theuerle, Ruth P Lim","doi":"10.1007/s10554-024-03290-w","DOIUrl":"10.1007/s10554-024-03290-w","url":null,"abstract":"<p><p>Bicuspid aortic valfves (BAV) are a relatively common cardiac abnormality, with an associated risk of aortic stenosis, aortic regurgitation and aortopathy. First-line diagnosis is via transthoracic echocardiography (TTE), which may be impacted by valve calcification and operator variability. Electrocardiogram-gated computed tomography (CT) offers an alternative form of assessment. The aim of this systematic review and meta-analysis is to evaluate the diagnostic performance of TTE versus CT for BAV. Eligible studies were retrieved from inception through to March 2024 on OVID Medline, Embase and Cochrane Library. All primary studies regarding the diagnostic performance of TTE and/or CT with regards to BAV were included. The QUADAS-2 tool was utilized for quality assessment. Sensitivity and specificity data were statistically analyzed. Of 4698 records, 19 were eligible for inclusion, and 16 had sufficient data for inclusion in the meta-analysis. There was only data regarding TTE vs. retrospectively ECG-gated CT. There was a significant difference between the sensitivity of retrospectively ECG-gated cardiac CT (95.5% (95% CI: [91.3-97.5%]) and TTE (79.7%, 95% CI: [71.6-86.0%]) for identifying BAV. The specificity was high and not significantly different for both CT and TTE (96%, 95% CI: [92.5-98.2%] and 91.3%, 95% CI: [87.3-93.8%], respectively). Retrospectively ECG-gated CT demonstrates greater sensitivity for diagnosis of BAV compared to TTE. Both modalities are non-invasive and demonstrate good specificity for excluding BAV. Given that CT scans are easily accessible, they offer a reasonable second-line investigation for diagnosis of BAV when an initial TTE is inconclusive.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"659-667"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142804162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Redundant and aneurysmal interatrial septum motion: a commentary on anatomical factors and clinical implications.","authors":"Altair Heidemann, Murilo Foppa","doi":"10.1007/s10554-025-03340-x","DOIUrl":"10.1007/s10554-025-03340-x","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"807"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143076750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disparities in quantification of mitral valve regurgitation between cardiovascular magnetic resonance imaging and trans-thoracic echocardiography: a systematic review.","authors":"Sulayman El Mathari, Rahul A Bhoera, Luuk H G A Hopman, Josephine Heidendael, Arjan Malekzadeh, Aart Nederveen, Pim van Ooij, Marco J W Götte, Jolanda Kluin","doi":"10.1007/s10554-024-03280-y","DOIUrl":"10.1007/s10554-024-03280-y","url":null,"abstract":"<p><p>Primary mitral regurgitation (MR) is a prevalent valvular heart disease. Therapy stratification for MR depends on accurate assessment of MR severity and left ventricular (LV) dimensions. While trans-thoracic echocardiography (TTE) has been the standard/preferred assessment method, cardiovascular magnetic resonance imaging (CMR) has gained recognition for its superior assessment of LV dimensions and MR severity. Both imaging modalities have their own advantages and limitation for therapy guidance. However, the differences between the two modalities for assessing/grade severity and clinical impact of MR remains unclear. This systematic review aims to evaluate the differences between TTE and CMR in quantifying MR severity and LV dimensions, providing insights for optimal clinical management. A literature search was performed from inception up to March 21st 2023. This resulted in 2,728 articles. After screening, 22 articles were deemed eligible for inclusion in the meta-analysis. The included study variables were, mitral valve regurgitation volume (MR_VOL), regurgitation fraction (MR_FRAC), LV end-diastolic volume (LVEDV), LV end-systolic volume (LVESV), LV stroke volume (LVSV), and LV ejection fraction (LVEF). TTE showed a significant higher MR_VOL (10.4 ml, I² = 88%, p = 0.002) and MR_FRAC (6.3%, I² = 51%, p = 0.05) compared to CMR, while CMR demonstrated a higher LVEDV (21.9 ml, I² = 66%, p =  < 0.001) and LVESV (16.8 ml, I² = 0%, p =  < 0.001) compared to TTE. Our findings demonstrate substantial disparities in TTE and CMR derived measurements for parameters that play a pivotal role in the clinical stratification guidelines. This discrepancy prompts a critical question regarding the prognostic value of both imaging modalities, which warrants future research.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"647-658"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Renal cell carcinoma tumor bulk extending to inferior vena cava and right atrium.","authors":"Hasan Hadzalic, Daniel Fritschi, Luca Oechslin, Patric Biaggi","doi":"10.1007/s10554-024-03303-8","DOIUrl":"10.1007/s10554-024-03303-8","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"815-816"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142793082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visualization of complex mitral valve anatomy using real-time three-dimensional computer graphics.","authors":"Kunihiko Joo, Yoshie Ochiai, Shigehiko Tokunaga","doi":"10.1007/s10554-024-03319-0","DOIUrl":"10.1007/s10554-024-03319-0","url":null,"abstract":"","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"821-822"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142916749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiotoxicity as important differential diagnosis for reduced myocardial blood flow during Rubidium cardiac PET/CT : Cardiotoxicity in Rubidium PET/CT.","authors":"Sabin G Pop, Eva Hägler, Cristina Popescu, Irene A Burger, Alexander W Sauter","doi":"10.1007/s10554-024-03315-4","DOIUrl":"10.1007/s10554-024-03315-4","url":null,"abstract":"<p><p>A 65-year-old woman with a history of ductal mammary carcinoma and recent autonomic dysfunction underwent a Rb-82 chloride (RbCl) cardiac PET/CT scan that showed no ischemia or scarring, but significantly reduced myocardial flow reserve (MFR) (global: 1.5) and a CAC-Score of 0. The patient's chemotherapy history (paclitaxel, carboplatin, epirubicin, pembrolizumab 2 years before) with elevated Troponin T and NT-pro-BNP levels at that time, and now reduced MFR with 0 CAC suggests cancer-therapy-related cardiotoxicity. An important differential diagnosis to the more common CAD-associated microvascular disease. Furthermore, tumor recurrence with a PET-avid lymph node metastasis was found additionally.</p>","PeriodicalId":94227,"journal":{"name":"The international journal of cardiovascular imaging","volume":" ","pages":"817-819"},"PeriodicalIF":0.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}